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Hongyue Wang, Ph.D.

About Me

Faculty Appointments

Research Associate Professor - Department of Biostatistics and Computational Biology (SMD)



PhD | University of Rochester. Statistics. 2007

MA | University of Rochester,. Statistics. 2001

BS | University of Science and Technology of China. Science and English. 1995


My research interests include the statistical methods of skewed data, longitudinal data analysis and survival analysis, and statistical methods in clinical trials and public health sciences.


Journal Articles

High-Intensity Telemedicine Decreases Emergency Department Use by Senior Living Community Residents.

Shah MN, Wasserman EB, Wang H, Gillespie SM, Noyes K, Wood NE, Nelson D, Dozier A, McConnochie KM

Telemedicine journal and e-health : the official journal of the American Telemedicine Association.. 2016 March 22 (3):251-8. Epub 08/07/2015.

High-Intensity Telemedicine Decreases Emergency Department Use for Ambulatory Care Sensitive Conditions by Older Adult Senior Living Community Residents.

Shah MN, Wasserman EB, Gillespie SM, Wood NE, Wang H, Noyes K, Nelson D, Dozier A, McConnochie KM

Journal of the American Medical Directors Association.. 2015 December 16 (12):1077-81. Epub 08/17/2015.

Urinary phthalate metabolite concentrations in relation to history of infertility and use of assisted reproductive technology.

Alur S, Wang H, Hoeger K, Swan SH, Sathyanarayana S, Redmon BJ, Nguyen R, Barrett ES

Fertility and sterility.. 2015 November 104 (5):1227-35. Epub 08/11/2015.

Observed parent-child relationship quality predicts antibody response to vaccination in children.

O'Connor TG, Wang H, Moynihan JA, Wyman PA, Carnahan J, Lofthus G, Quataert SA, Bowman M, Burke AS, Caserta MT

Brain, behavior, and immunity.. 2015 August 48 :265-73. Epub 04/09/2015.

Preterm cord blood CD4? T cells exhibit increased IL-6 production in chorioamnionitis and decreased CD4? T cells in bronchopulmonary dysplasia.

Misra R, Shah S, Fowell D, Wang H, Scheible K, Misra S, Huyck H, Wyman C, Ryan RM, Reynolds AM, Mariani T, Katzman PJ, Pryhuber GS

Human immunology.. 2015 May 76 (5):329-338. Epub 03/20/2015.

Unbound unconjugated hyperbilirubinemia is associated with central apnea in premature infants.

Amin SB, Wang H

The Journal of pediatrics.. 2015 March 166 (3):571-5. Epub 01/14/2015.

The Gluten-Free/Casein-Free Diet: A Double-Blind Challenge Trial in Children with Autism.

Hyman, S. L., Stewart, P. A., Foley, J., Cain, U., Peck, R., Morris, D. D., Wang, H., and Smith T.

Journal of Autism and Developmental Disorders. 2015; .

Some theoretical comparisons of negative binomial and zero-inflated Poisson distributions

Feng, C., Wang, H., Yu, H., Xia, Y., Lu, N., and Tu, X. M.

Communications in Statistics: Theory and Methods. 2015; 44(15): 3266-3277.

Generalized definition of the geometric mean of a nonnegative random variable.

Feng, C., Wang, H., Zhang, Y., Han, Y., Liang, Y., and Tu, X. M.

Communications in Statistics – Theory and Methods. 2015; : DOI:10.1080/03610926.2015.1066818.

On Testing Proportionality in the Cox Regression Model by Andersen's Plot

Feng, C., Wang, H., Zhang, Y., Han, Y., Liang, Y., and Tu, X. M.

Communications in Statistics – Theory and Methods. 2015; .

Auditory Neural Myelination is Associated with Early Childhood Language Development in Premature Infants

Amin, S.B., Vogler, D., Orlando, M., and Wang, H.

Early Human Development. 2014; 90(10): 673-678.

Early Developmental Outcomes of Children With Congenital HHV-6 Infection

Caserta, M. T., Hall, C. B., Canfield, R. L., Davidson, P., Lofthus, G., Schnabel, K., Carnahan, J., Shelley, L., and Wang, H.

Pediatrics. 2014; 134(6): 1111-1118.

Log-transformation and Its Implications for Data Analysis

Feng, C., Wang, H., Lu, N., Chen, T., He, H., Lu. Y., and Tu, X. M.

Shanghai Archives of Psychiatry. 2014; 26(2): 105-109.

On exact forms of Taylor's theorem for vector-valued functions

Feng, C., Wang, H., Chen, T. and Tu, X. M.

Biometrika. 2014; 101(4): 1003.

Parenteral Nutrition-Associated Cholestasis in Premature Infants: Role of Macronutrients

Gupta, K., Wang, H., and Amin, S. B.

J Parenter Enteral Nutr. 2014; : pii: 0148607114555161.

Prompting Asthma Intervention in Rochester-Uniting Parents and Providers (PAIR-UP): A Randomized Trial

Halterman, J. S., Fagnano, M., Tremblay, P. J., Fisher, S. G., Wang, H., Rand, C., Szilagyi, P., and Butz, A.

JAMA Pediatr. 2014; 168(10): e141983. doi: 10.1001/jamapediatrics.2014.1983.

Log-transformation: Application and Interpretation in Biomedical Research

Feng, C. Wang, H., Lu, N., and Tu, X. M.

Statistics in Medicine. 2013; 33(2): 230-239.

Latent iron deficiency in utero is associated with abnormal auditory neural myelination in ? 35 weeks gestational age infants

Amin, S.B., Orlando, M., and Wang, H.

The Journal of pediatrics. 2013; 163(5): 1267-1271.

Interdisciplinary simulation-based training to improve delivery room communication

Dadiz, R., Weinschreider, J., Schriefer, J., Arnold, C., Greves, C. D., Crosby, E. C., Wang, H., Pressman, E. K., and Guillet R.

Simul Healthc. 2013; 8(5): 279-291.

Geometric Mean of Nonnegative Random Variable

Feng, C., Wang, H., and Tu, X. M.

Communication in Statistics – Theory and Methods. 2013; 42(15): 2714-2717.

The mean value theorem and Taylor's expansion in statistics

Feng, C., Wang, H., Han, Y., Xia, Y., and Tu, X. M.

The American Statistician. 2013; 67(4): 245-248.

Percutaneous balloon dilation of Carpentier-Edwards porcine-valved right ventricle-to-pulmonary artery conduits

Hall, A. C., Miga, D. E., Leonard, G. T., Wang, H., Kavey, R. E., and Alfieris, G. M.

Pediatr Cardiol. 2013; 34(4): 978-983.

A Single Blinded Clinical Trial Comparing Polytrim and Moxifloxacin for Treatment of Conjunctivitis

Williams, L., Malhotra, Y., Murante, B., Laverty, S., Cook S., Topa, D., Hardy, D., Wang, H., and Gigliotti, F.

The Journal of Pediatrics. 2013; 162(4): 857-861.

Considerations in prophylaxis for tumor-associated epilepsy: prevention of status epilepticus and tolerability of newer generation AEDs

Wychowski, T., Wang, H., Buniak, L., Henry, J. C., and Mohile, N.

Clin Neurol Neurosurg. 2013; 115(11): 2365-2369.

Stability of T cell phenotype and functional assays following heparinized umbilical cord blood collection.

Scheible K, Secor-Socha S, Wightman T, Wang H, Mariani TJ, Topham DJ, Pryhuber G, Quataert S

Cytometry. Part A : the journal of the International Society for Analytical Cytology.. 2012 November 81 (11):937-49. Epub 10/01/2012.

Using Right Statistical Methods: Discussion of a Paper in Psychological Research

Feng, C., Wang, H. and Tu, X. M.

Surveys in Mathematics and Mathematical Sciences. 2012; 1(2): 81-87.

Association between neonatal iron overload and early human brain development in premature infants

Amin, S. B., Myers, G., Wang, H.

Early Hum Dev. 2012; 88(8): 583-587.

Proportionality of hazards in competing risk analysis

Feng, C. and Wang, H.

Statistics: A Journal of Theoretical and Applied Statistics. 2012; 47(4): 654-661.

A unified definition of conditional expectation and its application in survival analysis

Feng, C. Wang, H., and Tu, X. M.

Advances and Applications in Statistics. 2012; 27(2): 81-95.

The Asymptotic Distribution of a Likelihood Ratio Test for the Poisson Distribution

Feng, C., Wang, H., and Tu, X. M.

Sankhyá. 2012; 74(2): 263-268.

A Note on Generalized Inverses of Distribution Function and Quantile Transformation

Feng, C., Wang, H., Tu, X. M., and Kowalski, J.

Applied Mathematics. 2012; 2012(3): 2098-2100.

A Comparison of Two Test Statistics for Poisson Overdispersion/ Underdispersion

Wang, H., Feng, C., Tu, X. M., and Kowalski, J.

Applied Mathematics. 2012; 2012(3): 795-799.

Is Neonatal Jaundice Associated with Autism Spectrum Disorders: A Systematic Review

Amin, S. B., Smith, T., and Wang, H.

Journal of Autism and Developmental Disorders. 2011; 41(11): 1455-1463.

Associations among Depression, Perceived Self-Efficacy, and Immune Function and Health in Preadolescent Children

Caserta, M. T., Wyman, P. A., Wang, H., Moynihan, J., and O'Connor, T. G.

Development and Psychopathology. 2011; 23(4): 1139-1147.

Immunogenicity of Trivalent Influenza Vaccine in Extremely Low-birth-weight, Premature Versus Term Infants

D'Angio, C. T., Heyne, R. J., Duara, S., Holmes, L. C., O?shea, T. M., Wang, H., Wang, D., Sánchez, P.J., Welliver, R.C., Ryan, R.M., Schnabel, K.C., and Hall, C.B.

Pediatr Infect Dis J. 2011; 30(7): 570-574.

Likelihood Ratio Test Based Confidence Interval for the Relative Risk of Two Independent Binomial Samples

Feng, C., Wang, H., and Tu, X. M.

Journal of Applied Statistical Science,. 2011; 18(3): Article 10.

Randomized controlled trial to improve care for urban children with asthma: results of the School-Based Asthma Therapy trial

Halterman, J. S., Szilagyi, P. G., Fisher, S. G., Fagnano, M., Tremblay, P., Conn, K. M., Wang, H., and Borrelli, B.

Arch Pediatr Adolesc Med. 2011; 165(3): 262-268.

Restrictive Anorexia Nervosa and Set-Shifting in Adolescents: A Biobehavioral Interface

McAnarney, E. R., Zarcone, J. R., Singh, P, Welsh, S, Litteer, T, Wang, H., Klein, J.

Journal of Adolescent Health. 2011; 49(1): 99-101.

Histologic chorioamnionitis and acute neurologic impairment in premature infants

Amin, S. B., and Wang, H.

J Matern Fetal Neonatal Med. 2010; 23(10): 1165-1171.

Diagnostic assays for active infection with human herpesvirus 6 (HHV-6)

Caserta, M., Hall, C., Schnabel, K., Lofthus, G., Marino, A., Shelley, L., Yoo, C., Carnahan, J., Anderson, L., and Wang, H.

J Clin Virol. 2010; 48(1): 55-57.

A note on the concordance correlation coefficient

Feng, C., Ma, Y., Tu, X. M., and Wang, H.

Advances and Applications in Statistics. 2010; 15: 195-205.

Power Loss of Stratified Log-Rank Test in Homogeneous Samples

Feng, C., Wang, H., and Tu, X. M.

International Journal of Quality, Statistics, and Reliability. 2010; 2010: doi:10.1155/2010/942184.

A duality of sample size calculation based on odds ratio and on risk difference

Feng, C., Zhang, H., Wang, H., and Tu, X. M.

JP Journal of Biostatistics. 2010; 4(2): 203-212.

A Simple Method of Measuring Proximal Aortic Pulse Wave Velocity in Children: Methods and Normal Values

Jo, C., Lande, M., Meagher, C., Wang, H., and Vermilion, R.

Journal of the American Society of Echocardiography. 2010; 23(7): 735-740.

Parental Assessment of Executive Function and Internalizing and Externalizing Behavior in Primary Hypertension after Anti-Hypertensive Therapy

Lande, M., Adams, H., Falkner, B., Waldstein, S. R., Schwartz, G. J., Szilagyi, P. G., Wang, H., and Palumbo, D.

Journal of Pediatrics. 2010; 157(1): 114-119.

Product-Convolution of R-symmetric Unimodal Distributions: An Analogue of Wintner's Theorem

Mudholkar, G. S., and Wang, H.

Journal of Statistical Theory and Practice. 2010; 4(4): 803-811.

Perceptions of Weight and Appearance by Persons with Prader-Willi Syndrome and their Parents.

Zarcone, J., Napolitano, D., and Wang, H.

American Journal on Intellectual and Developmental Disabilities. 2010; 115(1): 43-53.

Confidence Bounds for the Relative Risk of Two Independent Binomial Distributions

Feng, C., Wang, H., and Tu, X. M.

Journal of Applied Statistical Science. 2010; 17: 583-592.

Parental Assessments of Internalizing and Externalizing Behavior and Executive Function in Children with Primary Hypertension

Lande, M., Adams, H., Falkner, B., Waldstein, S. R., Schwartz, G. J., Szilagyi, P. G., Wang, H., and Palumbo, D.

Journal of Pediatrics. 2009; 154(2): 207-212.

Intravenous Lipid and Bilirubin-Albumin Binding Variables in Premature Infants.

Amin, S. B., Harte, T., Scholer, L., and Wang, H.

Pediatrics. 2009; 124(1): 211-217.

In utero Iron Status and Auditory Neural Maturation in Premature Infants as Evaluated by Auditory Brainstem Response

Amin, S., MacDonald, M., Orlando, M., Eddins, A., Puccia, D., Moncznski, C., Lim, A., and Wang, H.

Journal of Pediatrics. 2009; 156(3): 377-381.

A Simple Nonparametric Approach of Survival Data with Two-Stage Outcomes of Different Scales

Feng, C., Ercoli, C., and Wang, H.

Advances and Applications in Statistics. 2009; 12(1): 1-9.

Testing Normality for Longitudinal Studies with Missing Data

Feng, C., Su, H., Wang, H., Tang, W., Yu, Q., and Tu, X. M.

Far East Journal of Theoretical Statistics. 2009; 28(2): 133-155.

Telemedicine Reduces Emergency Department Utilization and Overall Healthcare Expenditures for Illness Visits in Urban Children

McConnochie, K. M., Wood, N., Heredeen, H. E., Ng, P., Wang, H., and Roghmann, K.

Pediatrics. 2009; 123(6): 989-995.

R-Symmetry and the Power Function of the Tests for Inverse Gaussian Mean.

Mudholkar, G. S. and Wang, H.

Communication in Statistics, Theory meth. 2009; 38(13): 2178-2186.

Risk stratification for primary implantation of a cardioverter-defibrillator in patients with ischemic left ventricular dysfunction.

Goldenberg I, Vyas AK, Hall WJ, Moss AJ, Wang H, He H, Zareba W, McNitt S, Andrews ML,

Journal of the American College of Cardiology.. 2008 January 2251 (3):288-96. Epub 1900 01 01.

The Associations between Psychosocial Stress and the Frequency of Illness, and Innate and Adaptive Immune Function in Children

Caserta, M., O'Connor, T., Wyman, P., Wang, H., Moynihan, J., Cross, W., Tu, X., and Jin, X.

Brain, Behavior and Immunity. 2008; 22(6): 933-940.

Left ventricular mass index in children with white coat hypertension

Lande, M, Meagher, C., Fisher, S., Belani, P, Wang, H., and Rashid, M.

Journal of Pediatrics. 2008; 153(1): 50-54.

Pediatric Gastroenterology Fellows, Class of 2007: How well are they prepared for the future?

Qualia, C., Rossi, T. M., Wang, H., Baldwin, C., and Brown, M. R.

Journal of Pediatric Gastroenterology and Nutrition. 2008; 47: 327-333.

Development and validation of the general module of the system of quality of life instruments for cancer patients (QLICP-GM)

Wan, C. Yang, Z., Meng, Q., Feng, C., Wang, H., Tang, X., Zhang, C., Lu, Y., Luo, J., and Zhang, X.

International Journal of Cancer. 2008; 122(1): 190-196.

IG-symmetry and R-symmetry: Interrelations and Applications to the Inverse Gaussian Theory

Mudholkar, G. S. and Wang, H.

Journal of Statistical Planning and Inference. 2007; 137(1): 3655-3671.

Correlation Analysis for Longitudinal Data: Applications to HIV and Psychosocial Research

Tu, X. M., Feng, C., Kowalski, J., Tang, W., Wang, H., Wan, C., and Ma, Y.

Statistics in Medicine. 2007; 26(22): 4116-4138.

Validation of the simplified Chinese version of the FACT-B for measuring quality of life for patients with breast cancer

Wan, C., Zhang, D., Yang, Z., Tu, X. M., Tang, W., Feng, C., Wang, H., and Tang, X.

Breast Cancer Research and Treatment. 2007; 106(3): 413-418.

The Cost Effectiveness of Implantable Cardioverter-Defibrillators: Results from the Multicenter Automatic Defibrillator Implantation Trial (MADIT)-II.

Zwanziger, J., Hall, W. J., Dick, A. W., Zhao, H., Mushlin, A. I., Hahn, R. M., Wang, H., Andrews, M. L., Mooney, C., Wang, H., and Moss, A. J.

J Am Coll Cardiol. 2006; 47(11): 2310-2319.

Factors Influencing Appropriate Firing of the Implanted Defibrillator for Ventricular Tachycardia/Fibrillation

Singh, J. P., Hall, W. J., McNitt, S., Wang, H., Daubert, J. P., Zareba, W., Ruskin, J. N., and Moss, A. J.

Journal of the American College of Cardiology. 2005; 46(9): 1712-1720.

Clinical Course and Implantable Cardioverter Defibrillator Therapy in Postinfarction Women with Severe Left Ventricular Dysfunction

Zareba, W., Moss, A. J., Hall, W. J., Wilber, D. J., Ruskin, J. N., McNitt, S., Brown, M., and Wang, H.

Journal of Cardiovascular Electrophysiology. 2005; 16(12): 1265-1270.


Advances in Multivariate Statistical Methods (2009)

Chapter: The G-IG Analogies and Robust Tests for Inverse Gaussian Scale Parameters

Authors: Mudholkar, G. S., Wang, H., and Natarajan, R

Publisher: World Scientific, New Jersey 2009

Encyclopedia of Epidemiology (2007)

Chapter: Descriptive and Analytical Epidemiology

Authors: Hsieh, J. J., Feng, C., and Wang, H

Publisher: SAGE Publications, Thousand Oaks, CA 2007