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Tongtong Wu, Ph.D.

Tongtong Wu, Ph.D.

Contact

Office (585) 276-6858

About Me

Faculty Appointments

Professor - Department of Biostatistics and Computational Biology (SMD)

Research

Dr. Tong Tong Wu is a tenured Associate Professor in the Department of Biostatistics and Computational Biology (DBCB) at the University of Rochester. She is the Director of the M.A. in Statistics and M.S. in Medical Statistics programs in DBCB. She is also the Biostatistics Unit Leader in Core E (Bi...
Dr. Tong Tong Wu is a tenured Associate Professor in the Department of Biostatistics and Computational Biology (DBCB) at the University of Rochester. She is the Director of the M.A. in Statistics and M.S. in Medical Statistics programs in DBCB. She is also the Biostatistics Unit Leader in Core E (Biostatistics, Bioinformatics and Computational Biology) of Center for AIDS Research (CFAR) at UofR. She has been serving as an Associate Editor for the Annals of Applied Statistics since 2012.

Dr. Wu received her Ph.D. in Biostatistics from the Department of Biostatistics, UCLA School of Public Health in 2006. She then held a postdoctoral researcher position in the Department of Human Genetics, UCLA when visiting the Department of Statistics at Stanford University for about a year. She started as an Assistant Professor in the Department of Epidemiology and Biostatistics at the University of Maryland, College Park in 2007 and had been working at UMD for six years before moving to UofR in 2013.

As a biostatistician, Dr. Wu has interests in high-dimensional data analysis, survival analysis, machine learning, computational statistics, and computational biology and statistical genetics. She is also interested in statistical applications and collaborations in various health, medical, and scientific areas, such as cancer, HIV, epidemiology, psychology, and medical engineering. Dr. Wu was a co-Principal Investigator for a multi-site, collaborative NSF grant and a co-Principal Investigator for an NIH R21 grant. She has also served as a co-Investigator for many NIH funded R01 and R21 projects, as she directed and supervised the biostatistical aspects of those studies.

Publications

Journal Articles

Effect of Zinc on improving silver diamine fluoride-derived tooth discoloration in vitro.

Almulhim A, Valdivia-Tapia AC, Rocha GR, Wu Y, Mao X, Alomeir N, Benoit D, Hara AT, Wu TT, Xiao J, Li Y

BMC oral health.. 2024 November 1924 (1):1410. Epub 11/19/2024.

Effect of Zinc on Improving Silver Diamine Fluoride-derived Tooth Discoloration in Vitro.

Almulhim A, Valdivia-Tapia AC, Rocha GR, Wu Y, Mao X, Alomeir N, Benoit D, Hara AT, Wu TT, Xiao J, Li Y

Research square.. 2024 November 13 Epub 11/13/2024.

The role of regulatory focus types in the improvement of perinatal oral health knowledge among dental residents.

Kar KS, Cui S, Sanders M, Meng Y, Jallad NA, Wu T, Cacciato R, Xiao J

Journal of dental education.. 2024 October 27 Epub 10/27/2024.

Perception of Virtual Education Learning among Dental Residents and Faculty during the COVID-19 Pandemic: A Cross-Sectional Study.

Cui S, Kar KS, Vasani S, Al Jallad N, Sanders MR, Cacciato R, Wu TT, Xiao J, Malmstrom H

Dentistry journal.. 2024 July 2312 (8)Epub 07/23/2024.

The Health Benefits of Probiotic Lactiplantibacillus plantarum: A Systematic Review and Meta-Analysis.

Aljohani A, Rashwan N, Vasani S, Alkhawashki A, Wu TT, Lu X, Castillo DA, Xiao J

Probiotics and antimicrobial proteins.. 2024 May 31 Epub 05/31/2024.

Association between Salivary Hormones, Dental Caries, and Cariogenic Microorganisms during Pregnancy.

Yang R, Lu X, Alomeir N, Quataert S, Wu T, Xiao J

Journal of clinical medicine.. 2024 May 2913 (11)Epub 05/29/2024.

Parent-proxy pediatric CMT quality of life outcome measure: Validation of the Italian version.

Danti FR, Pagliano E, Pareyson D, Foscan M, Marchi A, Feoli A, Bruschi F, Piscosquito G, Shy ME, Ramchandren S, Moroni I, Wu TT

Journal of the peripheral nervous system : JPNS.. 2024 March 29 (1):107-110. Epub 02/08/2024.

Multilocus sequence typing of Candida albicans oral isolates reveals high genetic relatedness of mother-child dyads in early life.

Alkhars N, Al Jallad N, Wu TT, Xiao J

PloS one.. 2024 19 (1):e0290938. Epub 01/17/2024.

Maternal and infant oral health benefits from mothers receiving prenatal total oral rehabilitation: a pilot prospective birth cohort study.

Yang R, Rashwan N, Al Jallad N, Wu Y, Lu X, Wu T, Xiao J

Frontiers in oral health.. 2024 5 :1443337. Epub 08/13/2024.

Neuropathy due to bi-allelic SH3TC2 variants: genotype-phenotype correlation and natural history.

Rehbein T, Wu TT, Treidler S, Pareyson D, Lewis R, Yum SW, McCray BA, Ramchandren S, Burns J, Li J, Finkel RS, Scherer SS, Zuchner S, Shy ME, Reilly MM, Herrmann DN,

Brain : a journal of neurology.. 2023 September 1146 (9):3826-3835. Epub 1900 01 01.

Validation of the parent-proxy version of the pediatric Charcot-Marie-Tooth disease quality of life instrument for children aged 0-7?years.

Wu TT, Finkel RS, Siskind CE, Feely SME, Burns J, Reilly MM, Muntoni F, Milev E, Estilow OTT, Shy ME, Ramchandren S,

Journal of the peripheral nervous system : JPNS.. 2023 September 28 (3):382-389. Epub 05/18/2023.

Acceptance and Usability of an Innovative mDentistry eHygiene Model Amid the COVID-19 Pandemic Within the US National Dental Practice-Based Research Network: Mixed Methods Study.

Xiao J, Kopycka-Kedzierawski D, Ragusa P, Mendez Chagoya LA, Funkhouser K, Lischka T, Wu TT, Fiscella K, Kar KS, Al Jallad N, Rashwan N, Ren J, Meyerowitz C,

JMIR human factors.. 2023 August 1810 :e45418. Epub 08/18/2023.

Effects of Nystatin oral rinse on oral Candida species and Streptococcus mutans among healthy adults.

Aljaffary M, Jang H, Alomeir N, Zeng Y, Alkhars N, Vasani S, Almulhim A, Wu TT, Quataert S, Bruno J, Lee A, Xiao J

Clinical oral investigations.. 2023 July 27 (7):3557-3568. Epub 03/24/2023.

Dose-Dependent Inhibitory Effect of Probiotic on - Cross-Kingdom Microorganisms.

Bao J, Huang X, Zeng Y, Wu TT, Lu X, Meng G, Ren Y, Xiao J

Pathogens.. 2023 June 2012 (6)Epub 06/20/2023.

Impact of Nystatin Oral Rinse on Salivary and Supragingival Microbial Community among Adults with Oral Candidiasis.

Zhang L, Manning S, Wu TT, Zeng Y, Lee A, Wu Y, Paster BJ, Chen G, Fiscella K, Xiao J

Microorganisms.. 2023 June 511 (6)Epub 06/05/2023.

Model-based clustering of high-dimensional longitudinal data via regularization.

Yang L, Wu TT

Biometrics.. 2023 June 79 (2):761-774. Epub 04/28/2022.

Validation of the parent-proxy pediatric Charcot-Marie-Tooth disease quality of life outcome measure.

Wu TT, Finkel RS, Siskind CE, Feely SME, Burns J, Reilly MM, Muntoni F, Estilow T, Shy ME, Ramchandren S,

Journal of the peripheral nervous system : JPNS.. 2023 June 28 (2):237-251. Epub 02/17/2023.

Antifungal Susceptibility of Oral Isolates from Mother-Infant Dyads to Nystatin, Fluconazole, and Caspofungin.

Alkhars N, Gaca A, Zeng Y, Al-Jallad N, Rustchenko E, Wu TT, Eliav E, Xiao J

Journal of fungi.. 2023 May 179 (5)Epub 05/17/2023.

Anti-cariogenic Properties of in the Utilization of Galacto-Oligosaccharide.

Huang X, Bao J, Zeng Y, Meng G, Lu X, Wu TT, Ren Y, Xiao J

Nutrients.. 2023 April 2215 (9)Epub 04/22/2023.

Metagenomic analysis examines oral microbiome changes and interplay with immune response following prenatal total oral rehabilitation.

Wu TT, Sohn M, Manning S, Beblavy R, Gill S, Quataert S, Vasani S, Jang H, Zeng Y, Bruno J, Vazquez A, Fiscella K, Xiao J

Journal of translational medicine.. 2023 March 421 (1):172. Epub 03/04/2023.

Novel Clustering Methods Identified Three Caries Status-Related Clusters Based on Oral Microbiome in Thai Mother-Child Dyads.

Manning S, Xiao J, Li Y, Saraithong P, Paster BJ, Chen G, Wu Y, Wu TT

Genes.. 2023 March 314 (3)Epub 03/03/2023.

Effect of Probiotic on and Clinical Isolates from Children with Early Childhood Caries.

Zeng Y, Fadaak A, Alomeir N, Wu Y, Wu TT, Qing S, Xiao J

International journal of molecular sciences.. 2023 February 324 (3)Epub 02/03/2023.

Effect of Nystatin on Candida albicans - Streptococcus mutans duo-species biofilms.

Alomeir N, Zeng Y, Fadaak A, Wu TT, Malmstrom H, Xiao J

Archives of oral biology.. 2023 January 145 :105582. Epub 11/09/2022.

Dual transcriptome of and interplay in biofilms.

Xiao J, Zeng Y, Rustchenko E, Huang X, Wu TT, Falsetta ML

Journal of oral microbiology.. 2023 15 (1):2144047. Epub 11/09/2022.

Dynamics of oral microbiome acquisition in healthy infants: A pilot study.

Li Y, Saraithong P, Zhang L, Dills A, Paster BJ, Xiao J, Wu TT, Jones Z

Frontiers in oral health.. 2023 4 :1152601. Epub 03/30/2023.

Racial and oral health disparity associated with perinatal oral health care utilization among underserved US pregnant women.

Al Jallad N, Vasani S, Wu TT, Cacciato R, Thomas M, Lababede N, Lababede A, Xiao J

Quintessence international.. 2022 October 2153 (10):892-902. Epub 1900 01 01.

Validation of the Italian version of the pediatric CMT quality of life outcome measure.

Moroni I, Danti FR, Pareyson D, Pagliano E, Piscosquito G, Foscan M, Marchi A, Ardissone A, Genitrini S, Wu TT, Shy ME, Ramchandren S

Journal of the peripheral nervous system : JPNS.. 2022 June 27 (2):127-130. Epub 05/03/2022.

Semiparametric mixed-effects model for analysis of non-invasive longitudinal hemodynamic responses during bone graft healing.

Leon S, Ren J, Choe R, Wu TT

PloS one.. 2022 17 (4):e0265471. Epub 04/05/2022.

Disrupts Cross-Kingdom Biofilms.

Zeng Y, Fadaak A, Alomeir N, Wu TT, Rustchenko E, Qing S, Bao J, Gilbert C, Xiao J

Frontiers in cellular and infection microbiology.. 2022 12 :872012. Epub 03/22/2022.

Cerebral Blood Flow Hemispheric Asymmetry in Comatose Adults Receiving Extracorporeal Membrane Oxygenation.

Johnson TW, Dar IA, Donohue KL, Xu YY, Santiago E, Selioutski O, Marinescu MA, Maddox RK, Wu TT, Schifitto G, Gosev I, Choe R, Khan IR

Frontiers in neuroscience.. 2022 16 :858404. Epub 04/11/2022.

Clustering of longitudinal physical activity trajectories among young females with selection of associated factors.

Yang L, Young DR, Wu TT

PloS one.. 2022 17 (5):e0268376. Epub 05/12/2022.

Multimodal Data Integration Reveals Mode of Delivery and Snack Consumption Outrank Salivary Microbiome in Association With Caries Outcome in Thai Children.

Wu TT, Xiao J, Manning S, Saraithong P, Pattanaporn K, Paster BJ, Chen T, Vasani S, Gilbert C, Zeng Y, Li Y

Frontiers in cellular and infection microbiology.. 2022 12 :881899. Epub 05/23/2022.

Artificial intelligence-powered smartphone application, AICaries, improves at-home dental caries screening in children: Moderated and unmoderated usability test.

Al-Jallad N, Ly-Mapes O, Hao P, Ruan J, Ramesh A, Luo J, Wu TT, Dye T, Rashwan N, Ren J, Jang H, Mendez L, Alomeir N, Bullock S, Fiscella K, Xiao J

PLOS digital health.. 2022 1 (6)Epub 06/02/2022.

Assessment of an Innovative Mobile Dentistry eHygiene Model Amid the COVID-19 Pandemic in the National Dental Practice-Based Research Network: Protocol for Design, Implementation, and Usability Testing.

Xiao J, Meyerowitz C, Ragusa P, Funkhouser K, Lischka T, Mendez Chagoya LA, Al Jallad N, Wu TT, Fiscella K, Ivie E, Strange M, Collins J, Kopycka-Kedzierawsk DT

JMIR research protocols.. 2021 October 2610 (10):e32345. Epub 10/26/2021.

Assessing a Smartphone App (AICaries) That Uses Artificial Intelligence to Detect Dental Caries in Children and Provides Interactive Oral Health Education: Protocol for a Design and Usability Testing Study.

Xiao J, Luo J, Ly-Mapes O, Wu TT, Dye T, Al Jallad N, Hao P, Ruan J, Bullock S, Fiscella K

JMIR research protocols.. 2021 October 2210 (10):e32921. Epub 10/22/2021.

Oral microflora and pregnancy: a systematic review and meta-analysis.

Jang H, Patoine A, Wu TT, Castillo DA, Xiao J

Scientific reports.. 2021 August 1911 (1):16870. Epub 08/19/2021.

Changes in , and oral health conditions following Prenatal Total Oral Rehabilitation among underserved pregnant women.

Jang H, Al Jallad N, Wu TT, Zeng Y, Fadaak A, Malmstrom H, Fiscella K, Xiao J

Heliyon.. 2021 August 7 (8):e07871. Epub 08/26/2021.

Chlorthalidone with potassium citrate decreases calcium oxalate stones and increases bone quality in genetic hypercalciuric stone-forming rats.

Krieger NS, Asplin J, Granja I, Chen L, Spataru D, Wu TT, Grynpas M, Bushinsky DA

Kidney international.. 2021 May 99 (5):1118-1126. Epub 01/05/2021.

Development and Validation of the Pediatric Charcot-Marie-Tooth Disease Quality of Life Outcome Measure.

Ramchandren S, Wu TT, Finkel RS, Siskind CE, Feely SME, Burns J, Reilly MM, Estilow T, Shy ME,

Annals of neurology.. 2021 February 89 (2):369-379. Epub 12/07/2020.

Identification of Novel Biomarkers and Pathways for Coronary Artery Calcification in Nondiabetic Patients on Hemodialysis Using Metabolomic Profiling.

Chen W, Fitzpatrick J, Sozio SM, Jaar BG, Estrella MM, Riascos-Bernal DF, Wu TT, Qiu Y, Kurland IJ, Dubin RF, Chen Y, Parekh RS, Bushinsky DA, Sibinga NES

Kidney360.. 2021 February 2 (2):279-289. Epub 1900 01 01.

Machine Learning Approach Identified Multi-Platform Factors for Caries Prediction in Child-Mother Dyads.

Wu TT, Xiao J, Sohn MB, Fiscella KA, Gilbert C, Grier A, Gill AL, Gill SR

Frontiers in cellular and infection microbiology.. 2021 11 :727630. Epub 08/19/2021.

The Accuracy of Self-Reported Body Weight Is High but Dependent on Recent Weight Change and Negative Affect in Teenage Girls.

Koebnick C, Saksvig B, Li X, Sidell M, Wu TT, Young DR

International journal of environmental research and public health.. 2020 November 617 (21)Epub 11/06/2020.

Spatial frequency domain imaging for the longitudinal monitoring of vascularization during mouse femoral graft healing.

Ren J, Ramirez GA, Proctor AR, Wu TT, Benoit DSW, Choe R

Biomedical optics express.. 2020 October 111 (10):5442-5455. Epub 09/03/2020.

Oral health and Candida carriage in socioeconomically disadvantaged US pregnant women.

Xiao J, Fogarty C, Wu TT, Alkhers N, Zeng Y, Thomas M, Youssef M, Wang L, Cowen L, Abdelsalam H, Nikitkova A

BMC pregnancy and childbirth.. 2019 December 519 (1):480. Epub 12/05/2019.

Chlorthalidone Is Superior to Potassium Citrate in Reducing Calcium Phosphate Stones and Increasing Bone Quality in Hypercalciuric Stone-Forming Rats.

Krieger NS, Asplin JR, Granja I, Ramos FM, Flotteron C, Chen L, Wu TT, Grynpas MD, Bushinsky DA

Journal of the American Society of Nephrology : JASN.. 2019 July 30 (7):1163-1173. Epub 05/17/2019.

Penalized Empirical Likelihood for the Sparse Cox Regression Model.

Wang D, Wu TT, Zhao Y

Journal of statistical planning and inference.. 2019 July 201 :71-85. Epub 12/15/2018.

Patients with advanced chronic kidney disease and vascular calcification have a large hydrodynamic radius of secondary calciprotein particles.

Chen W, Anokhina V, Dieudonne G, Abramowitz MK, Kashyap R, Yan C, Wu TT, de Mesy Bentley KL, Miller BL, Bushinsky DA

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.. 2019 June 134 (6):992-1000. Epub 1900 01 01.

Diabetes Mellitus Modifies the Associations of Serum Magnesium Concentration With Arterial Calcification and Stiffness in Incident Hemodialysis Patients.

Chen W, Fitzpatrick J, Monroy-Trujillo JM, Sozio SM, Jaar BG, Estrella MM, Wu TT, Melamed ML, Parekh RS, Bushinsky DA

Kidney international reports.. 2019 June 4 (6):806-813. Epub 03/13/2019.

Human genes influence the interaction between Streptococcus mutans and host caries susceptibility: a genome-wide association study in children with primary dentition.

Meng Y, Wu T, Billings R, Kopycka-Kedzierawski DT, Xiao J

International journal of oral science.. 2019 May 3011 (2):19. Epub 05/30/2019.

Fully automated analysis of OCT imaging of human kidneys for prediction of post-transplant function.

Konkel B, Lavin C, Wu TT, Anderson E, Iwamoto A, Rashid H, Gaitian B, Boone J, Cooper M, Abrams P, Gilbert A, Tang Q, Levi M, Fujimoto JG, Andrews P, Chen Y

Biomedical optics express.. 2019 April 110 (4):1794-1821. Epub 03/13/2019.

Longitudinal Sedentary Time Among Females Aged 17 to 23 Years.

Young DR, Sidell MA, Koebnick C, Saksvig BI, Mohan Y, Cohen DA, Wu TT

American journal of preventive medicine.. 2019 April 56 (4):540-547. Epub 02/15/2019.

Social Network Spatial Model.

Ciminelli JT, Love T, Wu TT

Spatial statistics.. 2019 March 29 :129-144. Epub 11/20/2018.

A Randomized Controlled Trial of Liposomal Bupivacaine Parasternal Intercostal Block for Sternotomy.

Lee CY, Robinson DA, Johnson CA, Zhang Y, Wong J, Joshi DJ, Wu TT, Knight PA

The Annals of thoracic surgery.. 2019 January 107 (1):128-134. Epub 08/28/2018.

Prenatal Oral Health Care and Early Childhood Caries Prevention: A Systematic Review and Meta-Analysis.

Xiao J, Alkhers N, Kopycka-Kedzierawski DT, Billings RJ, Wu TT, Castillo DA, Rasubala L, Malmstrom H, Ren Y, Eliav E

Caries research.. 2019 53 (4):411-421. Epub 01/10/2019.

Obesity candidate genes, gestational weight gain, and body weight changes in pregnant women.

Groth SW, LaLonde A, Wu T, Fernandez ID

Nutrition.. 2018 April 48 :61-66. Epub 12/02/2017.

Candida albicans and Early Childhood Caries: A Systematic Review and Meta-Analysis.

Xiao J, Huang X, Alkhers N, Alzamil H, Alzoubi S, Wu TT, Castillo DA, Campbell F, Davis J, Herzog K, Billings R, Kopycka-Kedzierawski DT, Hajishengallis E, Koo H

Caries research.. 2018 52 (1-2):102-112. Epub 12/21/2017.

Optical coherence tomography and computer-aided diagnosis of a murine model of chronic kidney disease.

Wang B, Wang HW, Guo H, Anderson E, Tang Q, Wu T, Falola R, Smith T, Andrews PM, Chen Y

Journal of biomedical optics.. 2017 December 22 (12):1-11. Epub 1900 01 01.

High expression of Claudin-2 in esophageal carcinoma and precancerous lesions is significantly associated with the bile salt receptors VDR and TGR5.

Abu-Farsakh S, Wu T, Lalonde A, Sun J, Zhou Z

BMC gastroenterology.. 2017 February 1717 (1):33. Epub 02/17/2017.

Pre-existing neutralizing antibody mitigates B cell dysregulation and enhances the Env-specific antibody response in SHIV-infected rhesus macaques.

Jaworski JP, Bryk P, Brower Z, Zheng B, Hessell AJ, Rosenberg AF, Wu TT, Sanz I, Keefer MC, Haigwood NL, Kobie JJ

PloS one.. 2017 12 (2):e0172524. Epub 02/21/2017.

Bile salt receptor TGR5 is highly expressed in esophageal adenocarcinoma and precancerous lesions with significantly worse overall survival and gender differences.

Pang C, LaLonde A, Godfrey TE, Que J, Sun J, Wu TT, Zhou Z

Clinical and experimental gastroenterology. 2017 10 :29-37. Epub 02/07/2017.

An Exploration of Gene-Gene Interactions and Their Effects on Hypertension.

Meng Y, Groth S, Quinn JR, Bisognano J, Wu TT

International journal of genomics.. 2017 2017 :7208318. Epub 05/31/2017.

Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography.

Tang Q, Wang J, Frank A, Lin J, Li Z, Chen CW, Jin L, Wu T, Greenwald BD, Mashimo H, Chen Y

Biomedical optics express.. 2016 December 17 (12):5218-5232. Epub 11/21/2016.

Survival analysis with functional covariates for partial follow-up studies.

Fang HB, Wu TT, Rapoport AP, Tan M

Statistical methods in medical research.. 2016 December 25 (6):2405-2419. Epub 02/24/2014.

MCM4 and MCM7, potential novel proliferation markers, significantly correlated with Ki-67, Bmi1, and cyclin E expression in esophageal adenocarcinoma, squamous cell carcinoma, and precancerous lesions.

Choy B, LaLonde A, Que J, Wu T, Zhou Z

Human pathology.. 2016 November 57 :126-135. Epub 07/29/2016.

Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy.

Ramirez G, Proctor AR, Jung KW, Wu TT, Han S, Adams RR, Ren J, Byun DK, Madden KS, Brown EB, Foster TH, Farzam P, Durduran T, Choe R

Biomedical optics express.. 2016 September 17 (9):3610-3630. Epub 08/24/2016.

Matrix Completion Discriminant Analysis.

Wu TT, Lange K

Computational statistics & data analysis.. 2015 December 92 :115-125. Epub 1900 01 01.

Empirical Likelihood for Censored Linear Regression and Variable Selection.

Wu TT, Li G, Tang C

Scandinavian journal of statistics, theory and applications.. 2015 September 42 (3):798-812. Epub 01/27/2015.

High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7.

Huber AR, Tan D, Sun J, Dean D, Wu T, Zhou Z

BMC gastroenterology.. 2015 July 915 :80. Epub 07/09/2015.

Multilevel correlates of physical activity for early, mid, and late adolescent girls.

Young D, Saksvig BI, Wu TT, Zook K, Li X, Champaloux S, Grieser M, Lee S, Treuth MS

Journal of physical activity & health.. 2014 July 11 (5):950-60. Epub 05/13/2013.

Physical activity trajectories and multilevel factors among adolescent girls.

Zook KR, Saksvig BI, Wu TT, Young DR

The Journal of adolescent health : official publication of the Society for Adolescent Medicine.. 2014 January 54 (1):74-80. Epub 08/29/2013.

Statistical Learning Methods for Longitudinal High-dimensional Data.

Chen S, Grant E, Wu TT, Bowman FD

Wiley interdisciplinary reviews. Computational statistics.. 2014 January 6 (1):10-18. Epub 1900 01 01.

Pathway-gene identification for pancreatic cancer survival via doubly regularized Cox regression.

Gong H, Wu TT, Clarke EM

BMC systems biology.. 2014 8 Suppl 1 (Suppl 1):S3. Epub 01/24/2014.

Allostatic load may not be associated with chronic stress in pregnant women, NHANES 1999-2006.

Morrison S, Shenassa ED, Mendola P, Wu T, Schoendorf K

Annals of epidemiology.. 2013 May 23 (5):294-7. Epub 1900 01 01.

Nonlinear Vertex Discriminant Analysis with Reproducing Kernels.

Wu TT, Wu Y

Statistical analysis and data mining.. 2012 April 5 (2):167-176. Epub 1900 01 01.

A transcriptome analysis by lasso penalized Cox regression for pancreatic cancer survival.

Wu TT, Gong H, Clarke EM

Journal of bioinformatics and computational biology.. 2011 December 9 Suppl 1 :63-73. Epub 1900 01 01.

SEMIPARAMETRIC ADDITIVE RISKS REGRESSION FOR TWO-STAGE DESIGN SURVIVAL STUDIES.

Li G, Wu TT

Statistica Sinica.. 2010 October 20 (4):1581-1607. Epub 1900 01 01.

Nitric oxide is negatively correlated to pain during acute inflammation.

Hamza M, Wang XM, Wu T, Brahim JS, Rowan JS, Dionne RA

Molecular pain. 2010 September 156 :55. Epub 09/15/2010.

Quality of life in sarcoidosis: comparing the impact of ocular and non-ocular involvement of the disease.

Saligan LN, Levy-Clarke G, Wu T, Faia LJ, Wroblewski K, Yeh S, Nussenblatt RB, Sen HN

Ophthalmic epidemiology.. 2010 August 17 (4):217-24. Epub 1900 01 01.

Genome-wide association analysis by lasso penalized logistic regression.

Wu TT, Chen YF, Hastie T, Sobel E, Lange K

Bioinformatics.. 2009 March 1525 (6):714-21. Epub 01/28/2009.

A method for analyzing censored survival phenotype with gene expression data.

Wu T, Sun W, Yuan S, Chen CH, Li KC

BMC bioinformatics.. 2008 October 69 :417. Epub 10/06/2008.

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids.

Park CC, Ahn S, Bloom JS, Lin A, Wang RT, Wu T, Sekar A, Khan AH, Farr CJ, Lusis AJ, Leahy RM, Lange K, Smith DJ

Nature genetics.. 2008 April 40 (4):421-9. Epub 03/23/2008.

Repeated measures analyses of dose timing of antiretroviral medication and its relationship to HIV virologic outcomes.

Liu H, Miller LG, Golin CE, Hays RD, Wu T, Wenger NS, Kaplan AH

Statistics in medicine.. 2007 February 2826 (5):991-1007. Epub 1900 01 01.

Repeated measures longitudinal analyses of HIV virologic response as a function of percent adherence, dose timing, genotypic sensitivity, and other factors.

Liu H, Miller LG, Hays RD, Golin CE, Wu T, Wenger NS, Kaplan AH

Journal of acquired immune deficiency syndromes : JAIDS.. 2006 March 41 (3):315-22. Epub 1900 01 01.

Books

Molecular Diagnostics and Treatment of Pancreatic Cancer: Systems and Network Biology Approaches (2014)

Chapter: Statistical Analysis of High-Dimensional Data for Pancreatic Cancer

Authors: Gong, H.*, Wu, T.T.*$, and Clarke, E. (*: joint first authors) ($: corresponding author)

Publisher: Elsevier Academic Press 2014