Research Associate, Mass Spectrometry Resource Lab, Center for Advanced Research Technologies, University of Rochester School of Medicine & Dentistry 2021 - 2022

Education

Ph.D. | University of Rochester. Cell, Developmental, and Molecular Biology. 2021

M.S. | University of Rochester. Cell, Developmental, and Molecular Biology. 2017

B.S. | Lycoming College. Molecular & Cellular Biology. 2014

Awards

NERLSCD ABRF2025 Meeting Travel Award. 2025

ABRF Outstanding Scientist Scholarship. 2025

Travel Grant Award. 2019

Travel Grant Award. 2018

Upward Bound Fellowship. 2017

Research

Publications

Journal Articles

Long-lived mammals contain more phosphorylation sites in the SIRT6 C-terminus that enhance PARP1 interaction and resistance to oxidative stress.

Gigas J, Meadow ME, Guo J, Lan C, Hillpot E, Martinez JC, Tombline G, Bellomio P, Almodovar VR, Welle KA, Swovick K, Hryhorenko JR, Ablaeva J, Ghaemmaghami S, Seluanov A, Gorbunova V

bioRxiv : the preprint server for biology.. 2026 April 24 Epub 04/24/2026.

Taurine from tumour niche drives glycolysis to promote leukaemogenesis.

Sharma S, Rodems BJ, Baker CD, Kaszuba CM, Franco EI, Smith BR, Ito T, Swovick K, Welle K, Zhang Y, Rock P, Chaves FA, Ghaemmaghami S, Calvi LM, Ganguly A, Burack WR, Becker MW, Liesveld JL, Brookes PS, Munger JC, Jordan CT, Ashton JM, Bajaj J

Nature.. 2025 August 644 (8075):263-272. Epub 05/14/2025.

Proteome Birthdating: A Single-Sample Approach for Measuring Global Turnover Dynamics and "Protein Age".

Meadow ME, Broas S, Hoare M, Ahmed M, Alimohammadi F, Welle KA, Swovick K, Hryhorenko JR, Jain A, Martinez JC, Seluanov A, Gorbunova V, Buchwalter A, Ghaemmaghami S

Bio-protocol.. 2025 May 515 (9):e5296. Epub 05/05/2025.

Enzymatic Synthesis of Isotopically Labeled Hydrogen Peroxide for Mass Spectrometry-Based Applications.

Hoare M, Tan R, Militi I, Welle KA, Swovick K, Hryhorenko JR, Ghaemmaghami S

Journal of the American Society for Mass Spectrometry.. 2024 December 435 (12):3308-3312. Epub 10/04/2024.

Formylation facilitates the reduction of oxidized initiator methionines.

Tan R, Hoare M, Bellomio P, Broas S, Camacho K, Swovick K, Welle KA, Hryhorenko JR, Ghaemmaghami S

Proceedings of the National Academy of Sciences of the United States of America.. 2024 November 12121 (46):e2403880121. Epub 11/05/2024.

Proteome Birthdating Reveals Age-Selectivity of Protein Ubiquitination.

Meadow ME, Broas S, Hoare M, Alimohammadi F, Welle KA, Swovick K, Hryhorenko JR, Martinez JC, Biashad SA, Seluanov A, Gorbunova V, Buchwalter A, Ghaemmaghami S

Molecular & cellular proteomics : MCP.. 2024 July 23 (7):100791. Epub 05/24/2024.

Long lifetime and tissue-specific accumulation of lamin A/C in Hutchinson-Gilford progeria syndrome.

Hasper J, Welle K, Swovick K, Hryhorenko J, Ghaemmaghami S, Buchwalter A

The Journal of cell biology.. 2024 January 1223 (1)Epub 11/15/2023.

Protein extraction and sample preparation for LC-MS/MS (PDF)

Swovick, K.; Ghaemmaghami, S.

SUB Göttingen. 2024; 4(22/23): 1-3.

Folding stabilities of ribosome-bound nascent polypeptides probed by mass spectrometry.

Tan R, Hoare M, Welle KA, Swovick K, Hryhorenko JR, Ghaemmaghami S

Proceedings of the National Academy of Sciences of the United States of America.. 2023 August 15120 (33):e2303167120. Epub 08/08/2023.

Long lifetime and selective accumulation of the A-type lamins accounts for the tissue specificity of Hutchinson-Gilford progeria syndrome.

Hasper J, Welle K, Swovick K, Hryhorenko J, Ghaemmaghami S, Buchwalter A

bioRxiv : the preprint server for biology.. 2023 April 28 Epub 04/28/2023.

Folding stabilities of ribosome-bound nascent polypeptides probed by mass spectrometry

Ruiyue Tan; Margaret Hoare; Kevin A. Welle; Kyle Swovick; Jennifer R. Hryhorenko; Sina Ghaemmaghami.

PNAS. 2023; 120(33).

Interspecies Differences in Proteome Turnover Kinetics Are Correlated With Life Spans and Energetic Demands.

Swovick K, Firsanov D, Welle KA, Hryhorenko JR, Wise JP, George C, Sformo TL, Seluanov A, Gorbunova V, Ghaemmaghami S

Molecular & cellular proteomics : MCP.. 2021 20 :100041. Epub 01/07/2021.

Cross-species Comparison of Proteome Turnover Kinetics.

Swovick K, Welle KA, Hryhorenko JR, Seluanov A, Gorbunova V, Ghaemmaghami S

Molecular & cellular proteomics : MCP.. 2018 April 17 (4):580-591. Epub 01/10/2018.