Charles E. Sparks, M.D.
Contact
Charles E. Sparks, M.D.
About Me
Faculty Appointments
Professor Emeritus - Department of Pathology and Laboratory Medicine (SMD)
Credentials
Post-doctoral Training & Residency
Fellow, Biochemistry
Medical College of Pennsylvania 1976 - 1977
Fellow, Cardiopulmonary Medicine
University of Pennsylvania 1975 - 1976
Resident
Hospital of the University of
Pennsylvania (Clinical Pathology) 1972 - 1975
Intern
New York Hospital, Cornell (Medicine)
Naval Hospital, St. Albans (Rotating) 1968 - 1969
Education
MD | Jefferson Medical College. Medicine. 1968
BS | Mass Inst Technology. Biochemistry. 1963
Awards
Secretarial Appointee. Department of Veterans Affairs Medical Research Service Merit Review Subcommittee for Endocrinology (Chair: Endocrinology-A Review Board, Fall 2003, Spring & Fall 2004) 2002 - 2005
Co-Chair. Thrombogenic Factors and Recurrent Coronary Events Symposium, Perugia, Italy 1998
Co-Chair. National Symposium Meeting, American Diabetes Association, Lipoproteins, Diabetes and Atherosclerosis. 1988
Invited Speaker. Gordon Research Conference on Atherosclerosis: "Is intestinal apo B a determinant for lipoprotein recognition?" 1981
Conferee. Lipid Metabolism and Atherosclerosis, 1978, '79, '80, '81, '84, '86, '88, '90, '92, '96, '00, '04 Gordon Research Conference, Kimball Union Academy, Meriden, NH 1978 - 2004
Individual Research Service Award Grantee, National Institutes of Health 1975 - 1977
Chief Resident in Pathology, University of Pennsylvania 1974 - 1975
Research
Importance of the research is related to the role of apo B in lipid transport and as a factor associated with risk of arterial disease. Additional research focuses on the role of apo B as a risk factor in developing heart attacks, strokes, and in recurrent heart attacks in human populations.
Patents
Particle Stabilized Epitopes for Standardization
Issue date: June 16, 1997
Patent #: 171813
Country: Denmark
Inventors: Charles E Sparks, Janet D Sparks, Michael Violante
Particle Stabilized Epitopes for Standardization and Control of Immunoassays
Issue date: April 27, 1993
Patent #: 5,206,086
Country: United States
Inventors: Charles E Sparks, Janet D Sparks, Michael Violante
Particle Stabilized Epitopes for Standardization and Control of Immunoassays
Issue date: June 16, 1997
Patent #: 0312173
Country: Europe
Inventors: Charles E Sparks, Janet D Sparks, Michael Violante
Particle-Stabilized Epitopes for Standardization and Control of Immunoassays
Issue date: November 24, 1998
Patent #: 1,340,139
Country: Canada
Inventors: Charles E Sparks, Janet D Sparks, Michael Violante
Identifying Risk of a Medical Event
Issue date: March 17, 2015
Patent #: 8,979,753
Country: United States
Inventors: James P Corsetti, Arthur J Moss, Daniel H Ryan, Charles E Sparks
Publications
Journal Articles
Corsetti JP, Gansevoort RT, Bakker SJ, Sparks CE, Vart P, Dullaart RP
Journal of the American Society of Nephrology : JASN.. 2014 December 25 (12):2906-15. Epub 05/22/2014.
Sparks CE, Corsetti JP, Sparks JD
Current opinion in lipidology.. 2014 June 25 (3):230-2. Epub 1900 01 01.
Sparks CE, Sparks JD
Current opinion in lipidology.. 2013 October 24 (5):450-2. Epub 1900 01 01.
Corsetti JP, Salzman P, Ryan D, Moss AJ, Zareba W, Sparks CE
PloS one.. 2013 8 (7):e68920. Epub 07/09/2013.
Sparks JD, Sparks CE, Adeli K
Arteriosclerosis, thrombosis, and vascular biology.. 2012 September 32 (9):2104-12. Epub 07/12/2012.
Sparks CE, Sparks JD
Current opinion in lipidology.. 2012 August 23 (4):395-7. Epub 1900 01 01.
Corsetti JP, Gansevoort RT, Bakker SJ, Navis G, Sparks CE, Dullaart RP
Metabolism: clinical and experimental.. 2012 July 61 (7):996-1002. Epub 01/05/2012.
Sparks JD, Chamberlain J, O'Dell C, Khatun I, Hussain MM, Sparks CE
Biochemical and biophysical research communications.. 2011 March 11406 (2):252-6. Epub 02/18/2011.
Sparks JD, Cianci J, Jokinen J, Chen LS, Sparks CE
American journal of physiology. Gastrointestinal and liver physiology.. 2010 October 299 (4):G980-9. Epub 07/22/2010.
Corsetti JP, Ryan D, Rainwater DL, Moss AJ, Zareba W, Sparks CE
Arteriosclerosis, thrombosis, and vascular biology.. 2010 August 30 (8):1657-64. Epub 05/20/2010.
Corsetti JP, Gansevoort RT, Sparks CE, Dullaart RP
European journal of clinical investigation.. 2010 June 40 (6):483-9. Epub 04/14/2010.
Sparks CE, Sparks JD
Current opinion in lipidology.. 2010 June 21 (3):280-1. Epub 1900 01 01.
Corsetti JP, Ryan D, Rainwater DL, Moss AJ, Zareba W, Block RC, Sparks CE
Obesity.. 2008 December 16 (12):2717-22. Epub 10/16/2008.
Sparks JD, Sparks CE
The Journal of clinical investigation.. 2008 June 118 (6):2012-5. Epub 1900 01 01.
Corsetti JP, Ryan D, Moss AJ, Rainwater DL, Zareba W, Sparks CE
Arteriosclerosis, thrombosis, and vascular biology.. 2008 March 28 (3):548-54. Epub 12/20/2007.
Corsetti JP, Ryan D, Moss AJ, Zareba W, Sparks CE
Atherosclerosis.. 2008 January 196 (1):461-468. Epub 01/09/2007.
Corsetti, J.P.; Ryan, D.; Moss, A.J.; Rainwater, D.L.; Zareba, W.; Sparks, C.E.;.
Arterioscler Thromb Vasc Biol. 2008; 28(3): 548-54.
Sparks, J.D.; Sparks, C.E.;.
J Clin Invest. 2008; 118(6): 2012-5.
Corsetti JP, Ryan D, Moss AJ, Rainwater DL, Zareba W, Sparks CE
Diabetes.. 2007 May 56 (5):1429-35. Epub 02/15/2007.
Chirieac DV, Davidson NO, Sparks CE, Sparks JD
American journal of physiology. Gastrointestinal and liver physiology.. 2006 September 291 (3):G382-8. Epub 06/22/2006.
Corsetti JP, Zareba W, Moss AJ, Rainwater DL, Sparks CE
Atherosclerosis.. 2006 July 187 (1):191-7. Epub 10/20/2005.
Corsetti JP, Rainwater DL, Moss AJ, Zareba W, Sparks CE
Clinical chemistry.. 2006 July 52 (7):1331-8. Epub 05/18/2006.
Sparks JD, Collins HL, Chirieac DV, Cianci J, Jokinen J, Sowden MP, Galloway CA, Sparks CE
The Biochemical journal.. 2006 April 15395 (2):363-71. Epub 1900 01 01.
Corsetti JP, Zareba W, Moss AJ, Sparks CE
Atherosclerosis.. 2005 December 183 (2):293-300. Epub 05/31/2005.
Moss AJ, Ryan D, Oakes D, Goldstein RE, Greenberg H, Bodenheimer MM, Brown MW, Case RB, Dwyer EM, Eberly SW, Francis CW, Gillespie JA, Krone RJ, Lichstein E, MacCluer JW, Marcus FI, McCarthy J, Sparks CE, Zareba W
The American journal of cardiology.. 2005 July 1596 (2):177-82. Epub 1900 01 01.
Corsetti JP, Zareba W, Moss AJ, Sparks CE
Atherosclerosis.. 2004 December 177 (2):367-73. Epub 1900 01 01.
Chirieac DV, Collins HL, Cianci J, Sparks JD, Sparks CE
American journal of physiology. Endocrinology and metabolism.. 2004 July 287 (1):E42-9. Epub 02/17/2004.
Corsetti JP, Zareba W, Moss AJ, Ridker PM, Marder VJ, Rainwater DL, Sparks CE
Atherosclerosis.. 2003 December 171 (2):351-8. Epub 1900 01 01.
Fadl YY, Zareba W, Moss AJ, Marder VJ, Sparks CS, Miller Watelet LF, Carroll ER
Hypertension.. 2003 April 41 (4):943-9. Epub 03/10/2003.
Chirieac DV, Cianci J, Collins HL, Sparks JD, Sparks CE
Biochemical and biophysical research communications.. 2002 September 13297 (1):134-7. Epub 1900 01 01.
Harb TS, Zareba W, Moss AJ, Ridker PM, Marder VJ, Rifai N, Miller Watelet LF, Arora R, Brown MW, Case RB, Dwyer EM, Gillespie JA, Goldstein RE, Greenberg H, Hochman J, Krone RJ, Liang CS, Lichstein E, Little W, Marcus FI, Oakes D, Sparks CE, VanVoorhees L,
The American journal of cardiology.. 2002 January 1589 (2):216-21. Epub 1900 01 01.
Zareba W, Pancio G, Moss AJ, Kalaria VG, Marder VJ, Weiss HJ, Watelet LF, Sparks CE
Thrombosis and haemostasis.. 2001 September 86 (3):791-9. Epub 1900 01 01.
Chirieac DV, Chirieac LR, Corsetti JP, Cianci J, Sparks CE, Sparks JD
American journal of physiology. Endocrinology and metabolism.. 2000 November 279 (5):E1003-11. Epub 1900 01 01.
Sparks JD, Shaw WN, Corsetti JP, Bolognino M, Pesek JF, Sparks CE
Metabolism: clinical and experimental.. 2000 November 49 (11):1424-30. Epub 1900 01 01.
Fisher SD, Zareba W, Moss AJ, Marder VJ, Sparks CE, Hochman J, Liang C, Krone RJ,
The American journal of cardiology.. 2000 October 1586 (8):813-8. Epub 1900 01 01.
Collins HL, Sparks CE, Sparks JD
Biochemical and biophysical research communications.. 2000 July 14273 (3):1156-60. Epub 1900 01 01.
Kalaria VG, Zareba W, Moss AJ, Pancio G, Marder VJ, Morrissey JH, Weiss HJ, Sparks CE, Greenberg H, Dwyer E, Goldstein R, Watelet LF
The American journal of cardiology.. 2000 June 1585 (12):1401-8. Epub 1900 01 01.
Corsetti JP, Sparks JD, Peterson RG, Smith RL, Sparks CE
Atherosclerosis.. 2000 February 148 (2):231-41. Epub 1900 01 01.
Sowden MP, Collins HL, Smith HC, Garrow TA, Sparks JD, Sparks CE
The Biochemical journal.. 1999 August 1341 ( Pt 3) (Pt 3):639-45. Epub 1900 01 01.
Moss AJ, Goldstein RE, Marder VJ, Sparks CE, Oakes D, Greenberg H, Weiss HJ, Zareba W, Brown MW, Liang CS, Lichstein E, Little WC, Gillespie JA, Van Voorhees L, Krone RJ, Bodenheimer MM, Hochman J, Dwyer EM, Arora R, Marcus FI, Watelet LF, Case RB
Circulation.. 1999 May 1899 (19):2517-22. Epub 1900 01 01.
Van Mater D, Sowden MP, Cianci J, Sparks JD, Sparks CE, Ballatori N, Smith HC
Biochemical and biophysical research communications.. 1998 November 18252 (2):334-9. Epub 1900 01 01.
Sparks JD, Phung TL, Bolognino M, Cianci J, Khurana R, Peterson RG, Sowden MP, Corsetti JP, Sparks CE
Metabolism: clinical and experimental.. 1998 November 47 (11):1315-24. Epub 1900 01 01.
Moyer MP, Tracy RP, Tracy PB, van't Veer C, Sparks CE, Mann KG
Arteriosclerosis, thrombosis, and vascular biology.. 1998 March 18 (3):458-65. Epub 1900 01 01.
Phung TL, Roncone A, Jensen KL, Sparks CE, Sparks JD
The Journal of biological chemistry.. 1997 December 5272 (49):30693-702. Epub 1900 01 01.
Phung TL, Mooney RA, Kulas DT, Sparks CE, Sparks JD
Biochemical and biophysical research communications.. 1997 August 18237 (2):367-71. Epub 1900 01 01.
Sparks JD, Collins HL, Sabio I, Sowden MP, Smith HC, Cianci J, Sparks CE
Biochimica et biophysica acta.. 1997 July 121347 (1):51-61. Epub 1900 01 01.
Phung TL, Sowden MP, Sparks JD, Sparks CE, Smith HC
Metabolism: clinical and experimental.. 1996 September 45 (9):1056-8. Epub 1900 01 01.
Schock D, Kuo SR, Steinburg MF, Bolognino M, Sparks JD, Sparks CE, Smith HC
Proceedings of the National Academy of Sciences of the United States of America.. 1996 February 693 (3):1097-102. Epub 1900 01 01.
Sparks JD, Phung TL, Bolognino M, Sparks CE
The Biochemical journal.. 1996 January 15313 ( Pt 2) (Pt 2):567-74. Epub 1900 01 01.
Sparks JD, Sparks CE
Methods in enzymology.. 1996 263 :104-20. Epub 1900 01 01.
Sparks JD, Sparks CE
Biochemical and biophysical research communications.. 1994 November 30205 (1):417-22. Epub 1900 01 01.
Sparks JD, Sparks CE
Biochimica et biophysica acta.. 1994 November 171215 (1-2):9-32. Epub 1900 01 01.
Sparks JD, Corsetti JP, Sparks CE
Metabolism: clinical and experimental.. 1994 June 43 (6):681-90. Epub 1900 01 01.
Björnsson OG, Sparks JD, Sparks CE, Gibbons GF
European journal of clinical investigation.. 1994 February 24 (2):137-48. Epub 1900 01 01.
Harris SG, Sabio I, Mayer E, Steinberg MF, Backus JW, Sparks JD, Sparks CE, Smith HC
The Journal of biological chemistry.. 1993 April 5268 (10):7382-92. Epub 1900 01 01.
Corsetti JP, Sparks JD, Sikora B, Sparks CE
Hepatology : official journal of the American Association for the Study of Liver Diseases.. 1993 April 17 (4):645-50. Epub 1900 01 01.
Gibbons GF, Bartlett SM, Sparks CE, Sparks JD
The Biochemical journal.. 1992 November 1287 ( Pt 3) (Pt 3):749-53. Epub 1900 01 01.
Björnsson OG, Sparks JD, Sparks CE, Gibbons GF
Journal of lipid research.. 1992 July 33 (7):1017-27. Epub 1900 01 01.
Corsetti JP, Way BA, Sparks CE, Sparks JD
Hepatology : official journal of the American Association for the Study of Liver Diseases.. 1992 June 15 (6):1117-24. Epub 1900 01 01.
Sparks JD, Zolfaghari R, Sparks CE, Smith HC, Fisher EA
The Journal of clinical investigation.. 1992 May 89 (5):1418-30. Epub 1900 01 01.
Björnsson OG, Duerden JM, Bartlett SM, Sparks JD, Sparks CE, Gibbons GF
The Biochemical journal.. 1992 January 15281 ( Pt 2) (Pt 2):381-6. Epub 1900 01 01.
Corsetti JP, Sterry JA, Sparks JD, Sparks CE, Weintraub M
Clinical chemistry.. 1991 July 37 (7):1191-5. Epub 1900 01 01.
Corsetti JP, Weidner CH, Cianci J, Sparks CE
Analytical biochemistry.. 1991 May 15195 (1):122-8. Epub 1900 01 01.
Smith HC, Kuo SR, Backus JW, Harris SG, Sparks CE, Sparks JD
Proceedings of the National Academy of Sciences of the United States of America.. 1991 February 1588 (4):1489-93. Epub 1900 01 01.
Backus JW, Eagleton MJ, Harris SG, Sparks CE, Sparks JD, Smith HC
Biochemical and biophysical research communications.. 1990 July 31170 (2):513-8. Epub 1900 01 01.
Sparks JD, Sparks CE
The Journal of biological chemistry.. 1990 May 25265 (15):8854-62. Epub 1900 01 01.
Greenland P, Bowley NL, Meiklejohn B, Doane KL, Sparks CE
Clinical chemistry.. 1990 April 36 (4):628-30. Epub 1900 01 01.
Greenland P, Bowley NL, French CA, Meiklejohn B, Gagliano S, Sparks CE
American journal of public health.. 1990 February 80 (2):181-4. Epub 1900 01 01.
Kwong TC, Sparks JD, Pryce DJ, Cianci JF, Sparks CE
The Biochemical journal.. 1989 October 15263 (2):411-5. Epub 1900 01 01.
Sparks JD, Sparks CE, Miller LL
The Biochemical journal.. 1989 July 1261 (1):83-8. Epub 1900 01 01.
Jackson TK, Salhanick AI, Sparks JD, Sparks CE, Bolognino M, Amatruda JM
Diabetes.. 1988 September 37 (9):1234-40. Epub 1900 01 01.
Sparks JD, Sparks CE, Bolognino M, Roncone AM, Jackson TK, Amatruda JM
The Journal of clinical investigation.. 1988 July 82 (1):37-43. Epub 1900 01 01.
Sparks JD, Sparks CE, Roncone AM, Amatruda JM
The Journal of biological chemistry.. 1988 April 15263 (11):5001-4. Epub 1900 01 01.
Tetrault GA, Meiklejohn BA, Sparks CE
Clinical chemistry.. 1987 September 33 (9):1662-4. Epub 1900 01 01.
Sparks CE, Sparks JD, Bolognino M, Salhanick A, Strumph PS, Amatruda JM
Metabolism: clinical and experimental.. 1986 December 35 (12):1128-36. Epub 1900 01 01.
Sparks JD, Bolognino M, Trax PA, Sparks CE
Atherosclerosis.. 1986 September 61 (3):205-11. Epub 1900 01 01.
Sparks JD, Sparks CE, Kritchevsky D
Atherosclerosis.. 1986 May 60 (2):183-96. Epub 1900 01 01.
Shah NM, Eskin BA, Krouse TB, Sparks CE
Proceedings of the Society for Experimental Biology and Medicine.. 1986 March 181 (3):443-9. Epub 1900 01 01.
Kwong TC, Sparks JD, Sparks CE
Proceedings of the Society for Experimental Biology and Medicine.. 1985 February 178 (2):313-6. Epub 1900 01 01.
Sparks JD, Sparks CE
Advances in lipid research. 1985 21 :1-46. Epub 1900 01 01.
Garber DW, Gottlieb BA, Marsh JB, Sparks CE
The Journal of clinical investigation.. 1984 October 74 (4):1375-83. Epub 1900 01 01.
Krebs KE, Phillips MC, Sparks CE
Biochimica et biophysica acta.. 1983 May 16751 (3):470-3. Epub 1900 01 01.
Sparks CE, Rader DJ, Marsh JB
Journal of lipid research.. 1983 February 24 (2):156-66. Epub 1900 01 01.
Marsh JB, Sparks CE
Proceedings of the Society for Experimental Biology and Medicine.. 1982 June 170 (2):178-81. Epub 1900 01 01.
Rash JM, Rothblat GH, Sparks CE
Biochimica et biophysica acta.. 1981 November 23666 (2):294-8. Epub 1900 01 01.
Sparks CE, Hnatiuk O, Marsh JB
Canadian journal of biochemistry.. 1981 August 59 (8):693-9. Epub 1900 01 01.
Sparks CE, Tennenberg SD, Marsh JB
Biochimica et biophysica acta.. 1981 July 24665 (1):8-12. Epub 1900 01 01.
Sparks CE, Tennenberg SD, Marsh JB
Metabolism: clinical and experimental.. 1981 April 30 (4):354-8. Epub 1900 01 01.
Sparks CE, Marsh JB
Journal of lipid research.. 1981 March 22 (3):514-8. Epub 1900 01 01.
Sparks CE, Marsh JB
Journal of lipid research.. 1981 March 22 (3):519-27. Epub 1900 01 01.
Marsh JB, Sparks CE
The Journal of clinical investigation.. 1979 November 64 (5):1229-37. Epub 1900 01 01.
Marsh JB, Sparks CE
Metabolism: clinical and experimental.. 1979 October 28 (10):1040-5. Epub 1900 01 01.
Capuzzi DM, Sparks CE, DeHoff JL
Biochemical and biophysical research communications.. 1979 September 2790 (2):587-95. Epub 1900 01 01.
Sparks CE, Dehoff JL, Capuzzi DM, Pietra G, Marsh JB
Biochimica et biophysica acta.. 1978 April 28529 (1):123-30. Epub 1900 01 01.
Pietra GG, Spagnoli LG, Capuzzi DM, Sparks CE, Fishman AP, Marsh JB
The Journal of cell biology.. 1976 July 70 (1):33-46. Epub 1900 01 01.
BAGLIONI C, SPARKS CE
Developmental biology.. 1963 December 8 :272-85. Epub 1900 01 01.