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Elizabeth M. Pritchett, Ph.D.

Elizabeth M. Pritchett, Ph.D.

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Office (585) 275-7272

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About Me

Dr. Pritchett earned her bachelor’s degree in Biological Sciences from Georgia State University and her Ph.D. from the University of Delaware, where she studied gene expression changes in poultry across development and in response to heat stress. She joined the University of Rochester Genomics Resea...
Dr. Pritchett earned her bachelor’s degree in Biological Sciences from Georgia State University and her Ph.D. from the University of Delaware, where she studied gene expression changes in poultry across development and in response to heat stress. She joined the University of Rochester Genomics Research Center (GRC) in 2016, became faculty in 2026, and currently serves as Co-Director of the GRC.
At the GRC, Dr. Pritchett oversees complex genomics projects, guiding experimental design, sequencing strategy, and integration with downstream bioinformatics. She has extensive expertise in developing and optimizing library preparation methods across diverse and challenging sample types and has played a key role in implementing and expanding spatial transcriptomics technologies.
In addition to her technical leadership, Dr. Pritchett manages core laboratory operations and is deeply committed to education and outreach. She develops workshops, seminars, and training resources to support the research community and mentors trainees in emerging spatial technologies. She also extends these efforts into the broader community, engaging local students of all ages to promote STEM education and awareness of genomics.
She enjoys working closely with the research community to effectively leverage cutting-edge genomics technologies to answer complex biological questions.

Faculty Appointments

Research Assistant Professor - Department of Pediatrics, Center for Pediatric Biomedical Research (SMD)

Research

Publications

Journal Articles

Two riboswitch classes that share a common ligand-binding fold show major differences in the ability to accommodate mutations.

Srivastava Y, Akinyemi O, Rohe TC, Pritchett EM, Baker CD, Sharma A, Jenkins JL, Mathews DH, Wedekind JE

Nucleic acids research.. 2024 November 2752 (21):13152-13173. Epub 1900 01 01.

A riboswitch separated from its ribosome-binding site still regulates translation.

Schroeder GM, Akinyemi O, Malik J, Focht CM, Pritchett EM, Baker CD, McSally JP, Jenkins JL, Mathews DH, Wedekind JE

Nucleic acids research.. 2023 March 2151 (5):2464-2484. Epub 1900 01 01.

Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.

Kenney HM, Rangel-Moreno J, Peng Y, Chen KL, Bruno J, Embong A, Pritchett E, Fox JI, Becerril-Villanueva E, Gamboa-Domínguez A, Quataert S, Muthukrishnan G, Wood RW, Korman BD, Anolik JH, Xing L, Ritchlin CT, Schwarz EM, Wu CL

Frontiers in immunology.. 2023 14 :1237498. Epub 08/25/2023.

Defining the spatial-molecular map of fibrotic tendon healing and the drivers of Scleraxis-lineage cell fate and function.

Ackerman JE, Best KT, Muscat SN, Pritchett EM, Nichols AEC, Wu CL, Loiselle AE

Cell reports.. 2022 November 2241 (8):111706. Epub 1900 01 01.

Characterizing Neonatal Heart Maturation, Regeneration, and Scar Resolution Using Spatial Transcriptomics.

Misra A, Baker CD, Pritchett EM, Burgos Villar KN, Ashton JM, Small EM

Journal of cardiovascular development and disease.. 2021 December 219 (1)Epub 12/21/2021.

Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation.

Schroeder GM, Dutta D, Cavender CE, Jenkins JL, Pritchett EM, Baker CD, Ashton JM, Mathews DH, Wedekind JE

Nucleic acids research.. 2020 August 2048 (14):8146-8164. Epub 1900 01 01.

Transcriptomic changes throughout post-hatch development in Gallus gallus pituitary.

Pritchett EM, Lamont SJ, Schmidt CJ

Journal of molecular endocrinology.. 2017 January 58 (1):43-55. Epub 11/17/2016.

I. Evaluation of the impact of alternative light technology on male broiler chicken growth, feed conversion, and allometric characteristics.

Rogers AG, Pritchett EM, Alphin RL, Brannick EM, Benson ER

Poultry science.. 2015 March 94 (3):408-14. Epub 01/26/2015.

II. Evaluation of the impact of alternative light technology on male broiler chicken stress.

Rogers AG, Pritchett EM, Alphin RL, Brannick EM, Benson ER

Poultry science.. 2015 March 94 (3):331-7. Epub 02/25/2015.

Third Report on Chicken Genes and Chromosomes 2015.

Schmid M, Smith J, Burt DW, Aken BL, Antin PB, Archibald AL, Ashwell C, Blackshear PJ, Boschiero C, Brown CT, Burgess SC, Cheng HH, Chow W, Coble DJ, Cooksey A, Crooijmans RP, Damas J, Davis RV, de Koning DJ, Delany ME, Derrien T, Desta TT, Dunn IC, Dunn M, Ellegren H, Eöry L, Erb I, Farré M, Fasold M, Fleming D, Flicek P, Fowler KE, Frésard L, Froman DP, Garceau V, Gardner PP, Gheyas AA, Griffin DK, Groenen MA, Haaf T, Hanotte O, Hart A, Häsler J, Hedges SB, Hertel J, Howe K, Hubbard A, Hume DA, Kaiser P, Kedra D, Kemp SJ, Klopp C, Kniel KE, Kuo R, Lagarrigue S, Lamont SJ, Larkin DM, Lawal RA, Markland SM, McCarthy F, McCormack HA, McPherson MC, Motegi A, Muljo SA, Münsterberg A, Nag R, Nanda I, Neuberger M, Nitsche A, Notredame C, Noyes H, O'Connor R, O'Hare EA, Oler AJ, Ommeh SC, Pais H, Persia M, Pitel F, Preeyanon L, Prieto Barja P, Pritchett EM, Rhoads DD, Robinson CM, Romanov MN, Rothschild M, Roux PF, Schmidt CJ, Schneider AS, Schwartz MG, Searle SM, Skinner MA, Smith CA, Stadler PF, Steeves TE, Steinlein C, Sun L, Takata M, Ulitsky I, Wang Q, Wang Y, Warren WC, Wood JM, Wragg D, Zhou H

Cytogenetic and genome research.. 2015 145 (2):78-179. Epub 07/14/2015.

Application of the wireless electroencephalogram to measure stress in White Pekin ducks.

Pritchett EM, Rogers AG, Caputo MP, Benson ER, Alphin RL, Johnson AL

Research in veterinary science.. 2014 August 97 (1):162-8. Epub 06/06/2014.

Contextual modulation of androgen effects on agonistic interactions.

Pradhan DS, Connor KR, Pritchett EM, Grober MS

Hormones and behavior.. 2014 January 65 (1):47-56. Epub 12/05/2013.

Comparison of water-based foam and carbon dioxide gas mass emergency depopulation of White Pekin ducks.

Caputo MP, Benson ER, Pritchett EM, Hougentogler DP, Jain P, Patil C, Johnson AL, Alphin RL

Poultry science.. 2012 December 91 (12):3057-64. Epub 1900 01 01.