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Hiroshi Takayanagi, M.D., Ph.D.

Hiroshi Takayanagi, M.D., Ph.D.

Contact

Call Center (585) 276-3000

About Me

Faculty Appointments

Interim Professor (part-time) - Department of Microbiology and Immunology (SMD)

Interim Professor (part-time) - Department of Orthopaedics, Center for Musculoskeletal Research (SMD) - Joint

Publications

Journal Articles

HSP47 in Mitochondria: Roles in Apoptosis, Signal Transduction, and Protein and Virus Transportation.

Surinkaew S, Hosoya N, Ito H, Abe H, Nakanishi I, Matsumoto KI, Imai M, Kawakami F, Kubo M, Ichikawa T, Ichikawa H, Yonei Y, Beppu HJ, Suka J, Boonhok R, Chatatikun M, Sukati S, Piya-Amornphan N, Rungruangbaiyok C, Lektip C, Somsak V, Chaiswing L, Sompol P, Urano J, Moi ML, Takayanagi H, Indo HP, Majima HJ

Cells.. 2026 September 215 (17)Epub 09/02/2026.

A distinct antigen presentation pathway drives potent T cell immunity in lipid nanoparticle-based mRNA vaccines.

Muro R, Wang S, Ito-Kureha T, Huynh HH, Kobiyama K, Sugita T, Okamoto K, Nakano K, Okamura T, Kubo M, Ishii KJ, Nitta T, Takayanagi H

Science advances.. 2026 July 1712 (29):eaec7827. Epub 07/17/2026.

Inherent tissue homeostasis of the juvenile metaphysis provides a foundation for osteosarcoma development.

Saito M, Nakasuka F, Sankoda N, Wang Y, Taguchi J, Ohta S, Yamada Y, Ozawa M, Sakurai S, Kondo A, Ushiku T, Nakayama R, Nakamura M, Takayanagi H, Shibata A, Yamamoto T, Yamada Y

Nature communications.. 2026 June 2617 (1)Epub 06/26/2026.

Self-reinforcing IL-1β signaling accelerates the development and recurrence of TCF3::HLF-positive B-ALL.

Suzuki A, Shigehiro T, Hirakawa M, Hirano R, Tamai M, Akahane K, Okamoto K, Takayanagi H, Terashima Y, Ueha S, Kitami T, Takagi M, Keino D, Kato K, Kawaguchi H, Hino M, Yoshimura A, Inukai T, Ikawa T

Blood.. 2026 May 21147 (21):2472-2488. Epub 1900 01 01.

Activin A secretion by muscle-repairing macrophages induces heterotopic ossification in mice.

Yin W, Okamoto K, Terashima A, Pluemsakunthai W, Ono T, Ito-Kureha T, Akira S, Hashizume Y, Baron R, Ueha S, Matsushima K, Matzuk MM, Mishina Y, Takayanagi H

The Journal of clinical investigation.. 2026 March 2136 (5)Epub 03/02/2026.