CONTACT INFORMATIONCREDENTIALSPUBLICATIONSIngrid H. Sarelius, Ph.D.Contact InformationPhone NumbersOffice: (585) 275-7729Fax: (585) 273-2652Research LabsVisit Lab WebsiteLocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 711Rochester, NY 14642Faculty AppointmentsProfessor Emeritus - Department of Pharmacology and Physiology (SMD) BiographyResearchMy research focus is on vascular cell communication and signaling. Our lab is specifically interested in how the cells of the blood vessel wall communicate with each other, with the surrounding tissue, and with the blood itself. Basically, we're interested in figuring out how microvessels work! Since cardiovascular disease is a major killer of adult populations, and since much of this is vascular disease or disorder, understanding normal blood vessel function seems like a good place to start. The major tool that we use to ask our questions is confocal immunofluorescent intravital microscopy; we are one of a handful of labs worldwide that is able to image local events in cells of the vascular wall in real time in blood perfused microvessels in living animals. We also use single microparticle tracking to define the local fluid dynamic environment in vivo, and confocal imaging of signaling molecules and leukocyte populations in the in situ blood vessel.CredentialsEducation1968BSc | Massey UniversityPhysiology1972MSc(Hons) | Massey UniversityPhysiology1978PhD | University of Auckland, New ZealandPhysiologyPublicationsJournal Articles2/1/2016Sarelius IH, Titus PA, Maimon N, Okech W, Wilke-Mounts SJ, Brennan JR, Hocking DC. "Extracellular matrix fibronectin initiates endothelium-dependent arteriolar dilatation via the heparin-binding, matricryptic RWRPK sequence of the first type III repeat of fibrillar fibronectin." The Journal of physiology.. 2016 Feb 1; 594(3):687-97. Epub 2016 Jan 15. 11/1/2015Murrant CL, Sarelius IH. "Local control of blood flow during active hyperaemia: what kinds of integration are important?" The Journal of physiology.. 2015 Nov 1; 593(21):4699-711. Epub 2015 Sep 29. 2015Sarelius IH, Glading AJ. "Control of vascular permeability by adhesion molecules." Tissue barriers. 2015 3(1-2):e985954. Epub 2015 Apr 03. Books & Chapters2005 Chapter Title: Vascular control mechanisms in skeletal muscle. Book Title: Microvascular Research: Biology and Pathology Author List: Sarelius, I.H. Edited By: D. Shepro Published By: Academic Press 2005VIEW ALL PUBLICATIONSClose WindowSchedule an appointment with Ingrid H. Sarelius, Ph.D.Please answer the following questions to help us find the right appointment for you.Important: If you believe that you have a medical or psychiatric emergency, please call 911 or go to the nearest hospital. This website is not intended for emergency care.Have you seen this provider in the last 2 years?YesNoExisting Patient Schedule or request a follow up appointment online through MyChart. If you do not have a MyChart account, please close this window and call the appointment phone number. Ingrid H. Sarelius, Ph.D. is currently scheduling for the following appointment type(s): Our policy does not permit patients to establish care with multiple providers within the same practice or specialty without prior approval. If you choose a new provider in the same office, we will cancel the appointment. Please contact the office directly with questions on this policy.