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David Oakes, Ph.D.

Contact Information

Faculty Appointments

Biography

Research

After a period as Assistant Professor of Statistics at Harvard University I returned to London in 1977 as Senior Lecturer in Occupational Health Statistics at the London School of Hygiene and Tropical Medicine, where I became involved in the design and analysis of epidemiologic studies of cancer and respiratory diseases, and in the education of occupational health professionals.

Since coming to Rochester in 1983 I have become deeply involved in clinical trials of treatments for Parkinson's disease and Huntington's disease, and in cardiology. I have maintained my interest in environmental medicine through a long association with the Environmental Health Sciences Center. .

I have taught courses in undergraduate probability and statistics and a variety of graduate level courses, including probability, stochastic processes, statistical inference, statistical modeling techniques and survival analysis. I have been involved in the education of medical students and fellows. I hold a training grant in environmental health sciences biostatistics and am co-director of a training grant in experimental therapeutics in neurology. I have Chaired the Departments of Statistics (1989-95) and of Biostatistics (1995-2002 and 2007-2012)

My major research interests are in the area of univariate and multiivariate survival analysis and in the analysis of multiple event-time data. I have advised ten graduate students, Three (Ben Armstrong at London, Amita Manatunga at Emory. and Jong-Hyeon Jeong at Pittsburgh) are now full professors. Four others hold academic positions.

I am a Fellow of the American Statistical Association and the Institute of Mathematical Statistics and an elected member of the International Statistical Institute. I served on the NIH Study Sections "Biostatistical Methods and Research Design" and "Epidemiology of Cancer". I served as associate editor of the leading journal Biometrika from 1979-2008 , and am one of three Editors of the journal Lifetime Data Analysis. I have authored or co-authored over 150 publications. including methodologic papers in the statistical and biostatistical literature and collaborative works, in the medical literature. A selection of the methodologic papers is given below. My e-CV gives a complete list

Credentials

Education

1968
BA | UK - Non-Medical School
Arts & Sciences

1972
PhD | UK - Non-Medical School
Arts & Sciences

Awards

2005
Fellow
Sponsor: Institute of Mathematical Statistics

1994
Elected Member
Sponsor: International Statistical Institute

1993
Fellow
Sponsor: American Statistical Association

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Publications

Journal Articles

10/15/2022
Frank S, Testa C, Edmondson MC, Goldstein J, Kayson E, Leavitt BR, Oakes D, O'Neill C, Vaughan C, Whaley J, Gross N, Gordon MF, Savola JM, . "The Safety of Deutetrabenazine for Chorea in Huntington Disease: An Open-Label Extension Study." CNS drugs.. 2022 Oct 15; Epub 2022 Oct 15.

8/8/2022
Feigin A, Evans EE, Fisher TL, Leonard JE, Smith ES, Reader A, Mishra V, Manber R, Walters KA, Kowarski L, Oakes D, Siemers E, Kieburtz KD, Zauderer M, . "Pepinemab antibody blockade of SEMA4D in early Huntington's disease: a randomized, placebo-controlled, phase 2 trial." Nature medicine.. 2022 Aug 8; Epub 2022 Aug 08.

7/16/2022
Luo S, Zou H, Stebbins GT, Schwarzschild MA, Macklin EA, Chan J, Oakes D, Simuni T, Goetz CG, . "Dissecting the Domains of Parkinson's Disease: Insights from Longitudinal Item Response Theory Modeling." Movement disorders : official journal of the Movement Disorder Society.. 2022 Jul 16; Epub 2022 Jul 16.

Books & Chapters

2005
Chapter Title: On characterizing joint survivor functions by minima
Book Title: Proceedings of the Second Seattle Symposium in Biostatistics
Author List: Oakes, D
Edited By: D Y Lin and P J Heagerty
Published By: Springer 2005 in New York

2003
Book Title: Crossing Boundaries: Statistical Essays in Honor of Jack Hall
Author List: Kolassa, J.E. and Oakes, D (Eds.)
Published By: Institute of Mathematical Statistics Lecture Notes, Monographs Series # 43 2003

2001
Chapter Title: Biometrika Centenary: Survival Analysis
Book Title: Biometrika: One Hundred Years
Author List: Oakes, D
Edited By: D M Titterington and D R Cox
Published By: Oxford U.P. 2001 in Oxford

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Videos

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Rochester Panel Members Weigh In on Avandia Recommendation to FDA

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Rochester Panel Members Weigh In on Avandia Recommendation to FDA