David Oakes, Ph.D.

David Oakes, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 630
Rochester, NY 14642

Research Bio

After a period as Assistant Professor of Statistics at Harvard University I returned to London in 1977 as Senior Lecturer in Occupational Health Statistics at the London School of Hygiene and Tropical Medicine, where I became involved in the design and analysis of epidemiologic studies of cancer and respiratory diseases, and in the education of occupational health professionals.

Since coming to Rochester in 1983 I have become deeply involved in clinical trials of treatments for Parkinson's disease and Huntington's disease, and in cardiology. I have maintained my interest in environmental medicine through a long association with the Environmental Health Sciences Center. .

I have taught courses in undergraduate probability and statistics and a variety of graduate level courses, including probability, stochastic processes, statistical inference, statistical modeling techniques and survival analysis. I have been involved in the education of medical students and fellows. I hold a training grant in environmental health sciences biostatistics and am co-director of a training grant in experimental therapeutics in neurology. I have Chaired the Departments of Statistics (1989-95) and of Biostatistics (1995-2002 and 2007-2012)

My major research interests are in the area of univariate and multiivariate survival analysis and in the analysis of multiple event-time data. I have advised ten graduate students, Three (Ben Armstrong at London, Amita Manatunga at Emory. and Jong-Hyeon Jeong at Pittsburgh) are now full professors. Four others hold academic positions.

I am a Fellow of the American Statistical Association and the Institute of Mathematical Statistics and an elected member of the International Statistical Institute. I served on the NIH Study Sections "Biostatistical Methods and Research Design" and "Epidemiology of Cancer". I served as associate editor of the leading journal Biometrika from 1979-2008 , and am one of three Editors of the journal Lifetime Data Analysis. I have authored or co-authored over 150 publications. including methodologic papers in the statistical and biostatistical literature and collaborative works, in the medical literature. A selection of the methodologic papers is given below. My e-CV gives a complete list

Awards & Honors (National)

Fellow | Institute of Mathematical Statistics 2005
Elected Member | International Statistical Institute 1994
Fellow | American Statistical Association 1993

Recent Journal Articles

Showing the 5 most recent journal articles. 138 available »

2015 Nov 16
, Biglan KM, Shoulson I, Kieburtz K, Oakes D, Kayson E, Shinaman MA, Zhao H, Romer M, Young A, Hersch S, Penney J, Marder K, Paulsen J, Quaid K, Siemers E, Tanner C, Mallonee W, Suter G, Dubinsky R, Gray C, Nance M, Bundlie S, Radtke D, Kostyk S, Baic C, Caress J, Walker F, Hunt V, O'Neill C, Chouinard S, Factor S, Greenamyre T, Wood-Siverio C, Corey-Bloom J, Song D, Peavy G, Moskowitz C, Wesson M, Samii A, Bird T, Lipe H, Blindauer K, Marshall F, Zimmerman C, Goldstein J, Rosas D, Novak P, Caviness J, Adler C, Duffy A, Wheelock V, Tempkin T, Richman D, Seeberger L, Albin R, Chou KL, Racette B, Perlmutter JS, Perlman S, Bordelon Y, Martin W, Wieler M, Leavitt B, Raymond L, Decolongon J, Clarke L, Jankovic J, Hunter C, Hauser RA, Sanchez-Ramos J, Furtado S, Suchowersky O, Klimek ML, Guttman M, Sethna R, Feigin A, Cox M, Shannon B, Percy A, Dure L, Harrison M, Johnson W, Higgins D, Molho E, Nickerson C, Evans S, Hobson D, Singer C, Galvez-Jimenez N, Shannon K, Comella C, Ross C, Saint-Hilaire MH, Testa C, Rosenblatt A, Hogarth P, Weiner W, Como P, Kumar R, Cotto C, Stout J, Brocht A, Watts A, Eberly S, Weaver C, Foroud T, Gusella J, MacDonald M, Myers R, Fahn S, Shults C. "Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials." JAMA neurology. 2015 Nov 16; :1-9. Epub 2015 Nov 16.
2015 Sep 29
Oster E, Eberly SW, Dorsey ER, Kayson-Rubin E, Oakes D, Shoulson I. "Informativeness of Early Huntington Disease Signs about Gene Status." Journal of Huntington's disease. 2015 Sep 29; 4(3):271-7.
2015 Sep
Locascio JJ, Eberly S, Liao Z, Liu G, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Dhima K, Hung AY, Flaherty AW, Schwarzschild MA, Hayes MT, Wills AM, Shivraj Sohur U, Mejia NI, Selkoe DJ, Oakes D, Shoulson I, Dong X, Marek K, Zheng B, Ivinson A, Hyman BT, Growdon JH, Sudarsky LR, Schlossmacher MG, Ravina B, Scherzer CR. "Association between ?-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease." Brain : a journal of neurology. 2015 Sep; 138(Pt 9):2659-71. Epub 2015 Jul 28.
2015 Jun 15
Benhorin J, Bodenheimer M, Brown M, Case R, Dwyer EM, Eberly S, Francis C, Gillespie JA, Goldstein RE, Greenberg H, Haigney M, Krone RJ, Klein H, Lichstein E, Locati E, Marcus FI, Moss AJ, Oakes D, Ryan DH, Bloch Thomsen PE, Zareba W, . "Improving clinical practice guidelines for practicing cardiologists." The American journal of cardiology. 2015 Jun 15; 115(12):1773-6. Epub 2015 Mar 24.
Farmpton, M.W.; Pietropaoli, A., Dentler, M.; Chalupa, D; Little, E. L; Stewart L.; Frasier, M.; Oakes, D.; Wiltshire, J.; Vora, R.; and Utell, M.J. "Cardiovascualr effects of ozone in healthy subjects with and without deletion of glutathione S-transferase M1." Inhalation Toxicology. 2015; 27: 113-119.

Current Appointments

Professor - Department of Biostatistics and Computational Biology (SMD) - Primary
Professor - Department of Statistics A&S (RC)


PhD | Arts & Sciences | UK - Non-Medical School1972
BA | Arts & Sciences | UK - Non-Medical School1968