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Marilyn R. Brown, M.D.

Pediatrics

Clinical Interests

Advanced Nutrition Support; Gastroenterology, Nutrition

Contact Information

Phone Numbers

Appointment: (585) 275-2647

Office: (585) 275-2647

Fax: (585) 275-0707

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Biography

My main interests are in Parenteral Nutrition, Pediatric Nutrition & Inflammatory Bowel Disorders.

Professional Background

Dr. Brown is a Professor of Pediatrics at the Golisano Children's Hospital at the University of Rochester Medical Center (URMC). She is the Director of Education for Medical Students and Residents within the Division of Pediatric GI/Nutrition and she is also a member of the Scholarship Oversight Committee which oversees scholarly activity throughout each Pediatric Fellow's training.

Dr. Brown teaches a Pediatric Gastroenterology Elective for Pediatric Residents and fourth year medical students as well as coordinates the Pediatric GI electives for medical students and residents.

Dr. Brown earned her medical degree from the Unviersity of Rochester School of Medicine in Rochester, New York. Subsequently, she completed her residency in Pediatrics at The Genesee Hospital, Rochester General Hospital and Strong Memorial Hospital. She also completed a Fellowship in Physiology at the University of Rochester in Rochester, New York.

Research

Dr. Brown's primary research interest is Parenteral Nutrition.

Prokinetic agents in the treatment of gastroesophageal reflux in premature infants with Abhay Bhatt MD, Robert Sinkin MD, and Ronnie Guillet MD, 1998.

Limited Access Protocol for the Use of Oral Cisapride in the Treatment of Pediatric Patients with Refractory Gastroesophageal Reflux Disease and other Gastrointestinal Motility Disorders with Thomas M Rossi MD, 1999-2009.

3rd Generation Low Profile Balloon Gastrostomy Tube Insertion, Removal and Performance Study with Ross Products Division of Abbott Laboratories. Marilyn R. Brown with TM Rossi, TL Miller and RE Quiros 2001-2.

An open label, randomized, multiple dose, parallel multicenter study of Axid (Nizatidine) in the treatment of gastroesophageal reflux symptoms in pediatric subjects age 5days –18 years. Reliant Pharmaceuticals. Tracie L.Miller, Marilyn R. Brown. 2001.

Phase 3 double-masked, placebo-controlled study of alicaforsen (ISIS 2302), an Antisense Inhibitor of ICAM-1, for the treatment of patients with active Crohn's disease. ISIS Pharmaceuticals. Tracie L.Miller, Marilyn R. Brown, 2002.

A Phase II, Multi-Center, Open-Label Long-Term Study of the Safety Tolerability and Effectiveness of Intravenous antergren (natalizumab) in Adolescent Crohn's Disease. ELAN Pharmaceuticals. Tracie L. Miller, Brown MR. Completed 2005.

Pathways of differentiation of blood mononuclear cells in children with inflammatory bowel disease with Christopher Ritchlin, Juan Villalona, Cary Qualia, Marilyn R. Brown,Thomas Rossi, Koorosh Kooros and Natalie Sikka. IRB approved 05, several patients studied.

Brown MR, Nicchitta, J. Healthy habit goals for elevated body mass index: A program for the PCP. Tested in three Pediatric offices. Review done, Summer 2006.

Duration of pancreatic enzyme elevation in acute pancreatitis. Cary Qualia, Thomas Rossi, Brown MR, Asad Ullah. IRB approval 3/07

Specificity of the polyclonal antibody test system for human elastase-1 in stool in Cystic Fibrosis. Villalona J, Qualia C, Brown MR, Ren CL, Rossi T,. Data collection completed 3/07. Dr. Villalona writing up.

Eosinophilic Esophagitis in children: A retrospective review. Villalona, J, Brown MR, Rossi, TR, Katzman,P, Mathur, J. Finished in spring 06, waiting for Juan Villalona to finish the manuscript.

Evaluation of esophageal mucosa for filaggrin expression in patients with eosinophilic esophagitis. Qualia, C, Brown MR, Lisa Beck, Rossi, TR. Letter to Journal of Allergy and Clinical Immunology by Dr. Beck.

Review of Bravo pH studies in the Golisano Children's Hospital @ Strong Pediatric GI practice. Wahaj Zaidi, Thomas Rossi, Marilyn R. Brown. Poster In progress.

A phase 3, multi-center, randomized study to evaluate the safety, efficacy and pharmokinetics of the Human Anti-TNF Monoclonal antibody Adalimumab in pediatric subjects with moderate to severe Crohn's disease. Abbott Laboratories. Marilyn R. Brown. 2007-2009.

Hepatic portal eosinophilia in an adolescent girl taking tacrolimus after liver transplantation. Rene P. Myers, Anne B.Fender, Marilyn R. Brown, Charlotte K Ryan. Submitted to Pediatric Transplantation, August 2007, rejected

Choledochal cysts in children: Experience in New Delhi, India. Deepak Sobti, Devendra Gupta, Marilyn R. Brown. Poster presentation at Annual Poster Session of the Department of Pediatrics, October 2007.

Microarray analysis of peripheral blood and tissues of patients with immunemediated inflammatory diseases. Christopher Ritchlin, Edward Schwartz and others. IRB approval 6/07.

2007-present Co-Investigator, Autism Treatment Network: University of Rochester
ATN-INV-07-16. Principal investigator, Susan Hyman, MD. (Total direct costs: $150,000/yr x 3 yrs)

Koorosh Kooros, Heidi Connelly, Susan Hyman, Marilyn R. Brown. Sleep Studies with gastroesophageal reflux studies in children with autism spectrum disorder, 2010.

Credentials

Faculty Appointments

Specialties

  • Pediatric Gastroenterology
  • Pediatrics - American Board of Pediatrics

Education

1957
A.B. | Cornell University

1962
MD | University of Rochester School of Medicine and Dentistry
Medicine

1957-1960
| Cornell University Medical College
Medicine

Post-doctoral Training & Residency

07/01/1962 - 06/30/1963
Internship in at The Genesee Hospital

07/01/1963 - 06/30/1965
Residency in Pediatrics at University of Rochester Medical Center

Awards

2013
Albert Kaiser Medal of the Rochester Academy of Medicine

2010
Cambridge Who's Who

2007 - 2013
Best Doctors in America

2005
Rochester Academy of Medicine Award of Merit
Sponsor: University of Rochester
Location: Rochester, NY

2004
Ruth A Lawrence Faculty Service Award
Sponsor: University of Rochester
Location: Rochester, NY

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Publications

Journal Articles

2010
Mallah H.S.; Brown, M.R.; Rossi, T.R.; Block, R. "Parenteral Fish Oil-Associated Spur Cell Anemia". Journal of Pediatrics. 2010; 156 (2): 324-6.

2009
Katzman P J, Villalona J, Rossi TM, Brown MR. "Jejunal Atresia and Cystic Fibrosis in a Newborn Male Infant: A Case Report." Internet Journal of Pediatrics and Neonatology. 2009; 9: 1-6.

9/2008
Qualia CM, Baldwin CD, Rossi TM, Wang H, Brown MR. "Pediatric gastroenterology fellows, class of 2007: how well are they prepared for the future?" Journal of pediatric gastroenterology and nutrition.. 2008 Sep 0; 47(3):327-33.

Books & Chapters

1994
Chapter Title: Obesity in Adolescence
Book Title: Merck Manual
Author List: Brown MR
Published By: Merck and Company1994

1994
Chapter Title: Gastrointestinal Bleeding (Revised 1997, 2003, 2005 for new editions)
Book Title: Principles and Practice of Pediatrics
Author List: Brown MR
Edited By: F Oski, C DeAngelis, R Feigin, J Warshaw
Published By: J.B. Lippincott Company1994 in Philadelphia, PA

1992
Chapter Title: Constipation in the Adolescent
Book Title: Textbook of Adolescent Medicine
Author List: Brown MR
Edited By: McAnarney ER, Kreipe RE, Orr DP, Comerci GD
Published By: W.B. Saunders Company1992 in Philadelphia, PA

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