Dr. Brown's primary research interest is Parenteral Nutrition.
Prokinetic agents in the treatment of gastroesophageal reflux in premature infants with Abhay Bhatt MD, Robert Sinkin MD, and Ronnie Guillet MD, 1998.
Limited Access Protocol for the Use of Oral Cisapride in the Treatment of Pediatric Patients with Refractory Gastroesophageal Reflux Disease and other Gastrointestinal Motility Disorders with Thomas M Rossi MD, 1999-2009.
3rd Generation Low Profile Balloon Gastrostomy Tube Insertion, Removal and Performance Study with Ross Products Division of Abbott Laboratories. Marilyn R. Brown with TM Rossi, TL Miller and RE Quiros 2001-2.
An open label, randomized, multiple dose, parallel multicenter study of Axid (Nizatidine) in the treatment of gastroesophageal reflux symptoms in pediatric subjects age 5days –18 years. Reliant Pharmaceuticals. Tracie L.Miller, Marilyn R. Brown. 2001.
Phase 3 double-masked, placebo-controlled study of alicaforsen (ISIS 2302), an Antisense Inhibitor of ICAM-1, for the treatment of patients with active Crohn's disease. ISIS Pharmaceuticals. Tracie L.Miller, Marilyn R. Brown, 2002.
A Phase II, Multi-Center, Open-Label Long-Term Study of the Safety Tolerability and Effectiveness of Intravenous antergren (natalizumab) in Adolescent Crohn's Disease. ELAN Pharmaceuticals. Tracie L. Miller, Brown MR. Completed 2005.
Pathways of differentiation of blood mononuclear cells in children with inflammatory bowel disease with Christopher Ritchlin, Juan Villalona, Cary Qualia, Marilyn R. Brown,Thomas Rossi, Koorosh Kooros and Natalie Sikka. IRB approved 05, several patients studied.
Brown MR, Nicchitta, J. Healthy habit goals for elevated body mass index: A program for the PCP. Tested in three Pediatric offices. Review done, Summer 2006.
Duration of pancreatic enzyme elevation in acute pancreatitis. Cary Qualia, Thomas Rossi, Brown MR, Asad Ullah. IRB approval 3/07
Specificity of the polyclonal antibody test system for human elastase-1 in stool in Cystic Fibrosis. Villalona J, Qualia C, Brown MR, Ren CL, Rossi T,. Data collection completed 3/07. Dr. Villalona writing up.
Eosinophilic Esophagitis in children: A retrospective review. Villalona, J, Brown MR, Rossi, TR, Katzman,P, Mathur, J. Finished in spring 06, waiting for Juan Villalona to finish the manuscript.
Evaluation of esophageal mucosa for filaggrin expression in patients with eosinophilic esophagitis. Qualia, C, Brown MR, Lisa Beck, Rossi, TR. Letter to Journal of Allergy and Clinical Immunology by Dr. Beck.
Review of Bravo pH studies in the Golisano Children's Hospital @ Strong Pediatric GI practice. Wahaj Zaidi, Thomas Rossi, Marilyn R. Brown. Poster In progress.
A phase 3, multi-center, randomized study to evaluate the safety, efficacy and pharmokinetics of the Human Anti-TNF Monoclonal antibody Adalimumab in pediatric subjects with moderate to severe Crohn's disease. Abbott Laboratories. Marilyn R. Brown. 2007-2009.
Hepatic portal eosinophilia in an adolescent girl taking tacrolimus after liver transplantation. Rene P. Myers, Anne B.Fender, Marilyn R. Brown, Charlotte K Ryan. Submitted to Pediatric Transplantation, August 2007, rejected
Choledochal cysts in children: Experience in New Delhi, India. Deepak Sobti, Devendra Gupta, Marilyn R. Brown. Poster presentation at Annual Poster Session of the Department of Pediatrics, October 2007.
Microarray analysis of peripheral blood and tissues of patients with immunemediated inflammatory diseases. Christopher Ritchlin, Edward Schwartz and others. IRB approval 6/07.
2007-present Co-Investigator, Autism Treatment Network: University of Rochester
ATN-INV-07-16. Principal investigator, Susan Hyman, MD. (Total direct costs: $150,000/yr x 3 yrs)
Koorosh Kooros, Heidi Connelly, Susan Hyman, Marilyn R. Brown. Sleep Studies with gastroesophageal reflux studies in children with autism spectrum disorder, 2010.