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William H. Merigan, Jr., Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-4872

Research Labs

Faculty Appointments

  • Professor - Department of Ophthalmology (SMD)
  • Professor - Department of Center for Visual Science A&S (RC) - Joint
  • Professor - Department of Brain/Cognitive Sciences RC (RC) - Joint


Professional Background

Dr. Merigan's research examines the role of retinal ganglion cells in visual perception in the primate (human and macaque). The primate retina contains at least 14 different types of retinal ganglion cells, and each type forms a complete network across the retina. Because the size, shape andprojections of each of the cell types is distinctive, it is thought that they may play quite different and possibly independent roles invisual function,but at present relatively little is known about this question. Some clues about possible functions of different ganglion cell classes comes from their structure (some extend across large swaths of retina, while others get input from tiny regions of retina), their physiology (some ganglion cells respond to color, while others are color blind), and their projections into the brain (some ganglion cells project to visual cortex while others reach the superchiasmatic nucleus, which is thought to be important in diurnal rhythms).



BA | Boston College

MS | Univ of Maryland

PhD | Univ of Maryland
Psychology, All Other


Journal Articles

McGregor JE, Yin L, Yang Q, Godat T, Huynh KT, Zhang J, Williams DR, Merigan WH. "Functional architecture of the foveola revealed in the living primate." PloS one.. 2018 13(11):e0207102. Epub 2018 Nov 28.

Kotterman MA, Yin L, Strazzeri JM, Flannery JG, Merigan WH, Schaffer DV. "Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates." Gene therapy.. 2015 Feb 0; 22(2):116-26. Epub 2014 Dec 11.

Yang Q, Yin L, Nozato K, Zhang J, Saito K, Merigan WH, Williams DR, Rossi EA. "Calibration-free sinusoidal rectification and uniform retinal irradiance in scanning light ophthalmoscopy." Optics letters.. 2015 Jan 1; 40(1):85-8.