Skip to main content

Coronavirus (COVID-19): Visitor Restrictions, Resources, and Updates

Explore URMC
menu

William H. Merigan, Jr., Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-4872

Research Labs

Faculty Appointments

  • Professor - Department of Ophthalmology (SMD)
  • Professor - Department of Center for Visual Science A&S (RC) - Joint
  • Professor - Department of Brain/Cognitive Sciences RC (RC) - Joint

Biography

Professional Background

Dr. Merigan's research examines the role of retinal ganglion cells in visual perception in the primate (human and macaque). The primate retina contains at least 14 different types of retinal ganglion cells, and each type forms a complete network across the retina. Because the size, shape and projections of each of the cell types is distinctive, it is thought that they may play quite different and possibly independent roles invisual function,but at present relatively little is known about this question. Some clues about possible functions of different ganglion cell classes comes from their structure (some extend across large swaths of retina, while others get input from tiny regions of retina), their physiology (some ganglion cells respond to color, while others are color blind), and their projections into the brain (some ganglion cells project to visual cortex while others reach the suprachiasmatic nucleus, which is thought to be important in diurnal rhythms).

Credentials

Education

1967
BA | Boston College
Psychology

1972
MS | Univ of Maryland
Psychology

1975
PhD | Univ of Maryland
Psychology, All Other

Publications

Journal Articles

7/21/2020
Aboualizadeh E, Phillips MJ, McGregor JE, DiLoreto DA, Strazzeri JM, Dhakal KR, Bateman B, Jager LD, Nilles KL, Stuedemann SA, Ludwig AL, Hunter JJ, Merigan WH, Gamm DM, Williams DR. "Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution." Stem cell reports.. 2020 Jul 21; Epub 2020 Jul 21.

5/21/2020
Byrne LC, Day TP, Visel M, Strazzeri JA, Fortuny C, Dalkara D, Merigan WH, Schaffer DV, Flannery JG. "In vivo-directed evolution of adeno-associated virus in the primate retina." JCI insight.. 2020 May 21; 5(10)Epub 2020 May 21.

4/3/2020
McGregor JE, Godat T, Dhakal KR, Parkins K, Strazzeri JM, Bateman BA, Fischer WS, Williams DR, Merigan WH. "Optogenetic restoration of retinal ganglion cell activity in the living primate." Nature communications.. 2020 Apr 3; 11(1):1703. Epub 2020 Apr 03.

VIEW ALL PUBLICATIONS