Robert C. Griggs, M.D.

Robert C. Griggs, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box CU 420669
Rochester, NY 14642

Office: (585) 275-3707
Fax: (585) 276-2056

Professional Bio

Dr. Griggs is Professor of Neurology, Medicine, Pathology and Laboratory Medicine, Pediatrics and Center for Human Experimental Therapeutics at the University of Rochester School of Medicine and Dentistry. He was Chair of the Department of Neurology at the University of Rochester (1986-2008). He received his BA from the University of Delaware and his M.D. from the University of Pennsylvania. He received training in Internal Medicine at Case Western Reserve University and the University of Rochester where he was Chief Resident in Medicine and Fellow in Immunology. He trained in Neurology at the National Institute of Neurological Disorders and Stroke and the University of Rochester. Dr. Griggs is an internist/neurologist specializing in neuromuscular diseases with a focus on experimental therapeutics. He has directed an NIH-funded training program in the Experimental Therapeutics of Neurological Disease since 1989. He has published over 350 scientific papers and 24 texts which span the fields of medicine and neurology. He served as President of the Association of University Professor of Neurology (1994-1996). He has served on the Council of the American Neurological Association. He served as Editor-in-Chief of Neurology (1997-2007).

He is Neurology Editor of Cecil Textbook of Medicine and an Editor of Cecil Essentials of Medicine. He was elected to the Institute of Medicine of the National Academy of Sciences in 1998. Dr. Griggs was President (2009-2011) of the American Academy of Neurology.

Research Bio

Dr. Griggs is Professor of Neurology, Medicine, Pathology and Laboratory Medicine, Pediatrics Center for Human Experimental Therapeutics at the University of Rochester School of Medicine and Dentistry. He served as Chair of the Department of Neurology and Neurologist-in-Chief at Strong Memorial Hospital 1986-2008. He received his BA from the University of Delaware and his M.D. from the University of Pennsylvania. He received training in Internal Medicine at Case Western Reserve University and the University of Rochester where he was Chief Resident in Medicine and Fellow in Immunology. He trained in Neurology at the National Institute of Neurological Disorders and Stroke (NINDS) and the University of Rochester where he was Chief Resident in Neurology.



Dr. Griggs' research interests are focused on developing new treatments for neuromuscular diseases. He has developed treatments for the periodic paralyses, non-dystrophic myotonia, Duchenne muscular dystrophy and inflammatory myopathies. He has directed an NIH-funded (1990-2015) training program in the Experimental Therapeutics of Neurological Disease since 1989.

Since 1998, Dr. Griggs has chaired the Executive Committee of the Muscle Study Group (MSG), an international consortium of investigators focused on developing new treatments for neuromuscular disease. The MSG is supported by grants from the National Institute of Health, Food and Drug Administration, industry, and a number of foundations. Dr. Griggs is currently principal investigator of the NIH-funded studies: "Acetazolamide vs Dichlorphenamide vs Placebo in Periodic Paralysis (HYP HOP), Double-blind Randomized Trial to Optimize Steroid Regimen in Duchenne Muscular Dystrophy (FOR-DMD) – a 40 center, 5 country study, and a 10 center Rare Disease Consortium: Clinical Investigation of Neurological Channelopathies (CINCH) which focuses on periodic paralysis, non-dystrophic myotonia and episodic ataxia.

Awards & Honors (Local)

Amicus 8, Faculty of Medicine, Jagiellonian University, Krakow, Poland 2007 - Present
Woodward/White, Inc., The Best Doctors in America (listed since 1981) 2003
Honorary Member, French Neurological Society 2000
Rochester Academy of Medicine Award of Merit, Rochester, New York 1998
Elected, Institute of Medicine of the National Academy of Sciences 1998
Visiting Fellow, Department of Biochemistry, University of Leicester (Training in molecular biology in the laboratory of David Critchley, Ph.D.) 1990 - 1990
Burroughs Wellcome Traveling Research Fellowship, Leicester, U.K. (Laboratory of D. Critchley, Ph.D.) 1990
Mentor Award, University of Rochester 1984 - 1985
Albert H. Douglas, M.D. Memorial Award for Excellence in Clinical Teaching. Medical Society of the State of New York 1984
Senior Fellow, Fogarty International Center, National Institutes of Health 1981 - 1982
Dr. Henry C. and Bertha H. Buswell Distinguished Service Fellow, School of Medicine, University of Rochester 1980 - 1981
Fellow, Neuroscience Research Program; Boulder, Colorado 1972
American College of Physicians Research and Teaching Scholarship 1971 - 1974
Special Research Fellowship, National Institute of Neurological Diseases and Stroke; Bethesda, Maryland 1970 - 1971

Recent Journal Articles

Showing the 5 most recent journal articles. 337 available »

2016 Apr 12
Sansone VA, Burge J, McDermott MP, Smith PC, Herr B, Tawil R, Pandya S, Kissel J, Ciafaloni E, Shieh P, Ralph JW, Amato A, Cannon SC, Trivedi J, Barohn R, Crum B, Mitsumoto H, Pestronk A, Meola G, Conwit R, Hanna MG, Griggs RC, . "Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis." Neurology. 2016 Apr 12; 86(15):1408-16. Epub 2016 Feb 10.
2016 Apr
Jen JC, Ashizawa T, Griggs RC, Waters MF. "Rare neurological channelopathies--networks to study patients, pathogenesis and treatment." Nature reviews. Neurology. 2016 Apr; 12(4):195-203. Epub 2016 Mar 04.
2016 Feb
Tomlinson SE, Tan SV, Burke D, Labrum RW, Haworth A, Gibbons VS, Sweeney MG, Griggs RC, Kullmann DM, Bostock H, Hanna MG. "In vivo impact of presynaptic calcium channel dysfunction on motor axons in episodic ataxia type 2." Brain : a journal of neurology. 2016 Feb; 139(Pt 2):380-91.
2016 Jan
Gatheridge MA, Kwon JM, Mendell JM, Scheuerbrandt G, Moat SJ, Eyskens F, Rockman-Greenberg C, Drousiotou A, Griggs RC. "Identifying Non-Duchenne Muscular Dystrophy-Positive and False Negative Results in Prior Duchenne Muscular Dystrophy Newborn Screening Programs: A Review." JAMA neurology. 2016 Jan; 73(1):111-6.
2015 Sep 15
Pieper KM, Griggs RC. "WriteClick nonresponders: Waiting, waffling, or weasling?" Neurology. 2015 Sep 15; 85(11):924.

Current Appointments

Professor - Department of Neurology (SMD) - Primary
Professor - Department of Medicine (SMD)
Professor - Department of Pathology and Laboratory Medicine (SMD)
Professor - Department of Pediatrics (SMD)

Specialties

Neurology - American Board of Psychiatry and Neurology
Vascular Neurology - American Board of Psychiatry and Neurology
Internal Medicine - American Board of Internal Medicine

Education

MD | Medicine | Univ Pennsylvania Sch Medicine1964
BA | Chemistry | University of Delaware1960

Post-Doctoral Training & Residency

Residency in Internal Medicine at University of Rochester Medical Center09/01/1968 - 06/30/1971
Residency in Neurology at National Institutes of Neurological Diseases and Blindness09/01/1966 - 06/30/1968
Internship in Internal Medicine at Case Western Reserve University School of Dentistry09/01/1964 - 06/30/1966