Skip to main content
Explore URMC

Marc W. Halterman, M.D., Ph.D.


Showing all 51 journal articles & 0 books available

Journal Articles

Li Y, Schor J, Bartko J, Albert G, Halterman MW. "The transcription factor C/EBP? promotes vascular endothelial growth factor A expression and neural stem cell expansion." FEBS letters.. 2022 May 20; Epub 2022 May 20.

Li Y, Halterman MW. "The MAP Kinase Phosphatase MKP-1 Modulates Neurogenesis via Effects on BNIP3 and Autophagy." Biomolecules.. 2021 Dec 14; 11(12)Epub 2021 Dec 14.

Mai N, Knowlden SA, Miller-Rhodes K, Prifti V, Sims M, Grier M, Nelson M, Halterman MW. "Effects of 9-t-butyl doxycycline on the innate immune response to CNS ischemia-reperfusion injury." Experimental and molecular pathology.. 2020 Dec 29; :104601. Epub 2020 Dec 29.

Simpkins AN, Busl KM, Amorim E, Barnett-Tapia C, Cervenka MC, Dhakar MB, Etherton MR, Fung C, Griggs R, Holloway RG, Kelly AG, Khan IR, Lizarraga KJ, Madagan HG, Onweni CL, Mestre H, Rabinstein AA, Rubinos C, Dionisio-Santos DA, Youn TS, Merck LH, Maciel CB, . "Proceedings from the Neurotherapeutics Symposium on Neurological Emergencies: Shaping the Future of Neurocritical Care." Neurocritical care.. 2020 Sep 21; Epub 2020 Sep 21.

Mai N, Prifti V, Lim K, O'Reilly MA, Kim M, Halterman MW. "Lung SOD3 limits neurovascular reperfusion injury and systemic immune activation following transient global cerebral ischemia." Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.. 2020 Sep; 29(9):104942. Epub 2020 May 14.

Bartko JC, Li Y, Sun Z, Halterman MW. "Phosphorylation within the bipartite NLS alters the localization and toxicity of the ER stress response factor DDIT3/CHOP." Cellular signalling.. 2020 Jul 13; :109713. Epub 2020 Jul 13.

Mai N, Prifti V, Kim M, Halterman MW. "Characterization of neutrophil-neuronal co-cultures to investigate mechanisms of post-ischemic immune-mediated neurotoxicity." Journal of neuroscience methods.. 2020 May 20; :108782. Epub 2020 May 20.

Trzeciak A, Lerman YV, Kim TH, Kim MR, Mai N, Halterman MW, Kim M. "Long-Term Microgliosis Driven by Acute Systemic Inflammation." The Journal of immunology : official journal of the American Association of Immunologists.. 2019 Oct 16; Epub 2019 Oct 16.

Mai N, Miller-Rhodes K, Prifti V, Kim M, O'Reilly MA, Halterman MW. "Lung-Derived SOD3 Attenuates Neurovascular Injury After Transient Global Cerebral Ischemia." Journal of the American Heart Association.. 2019 May 7; 8(9):e011801.

Mai N, Miller-Rhodes K, Knowlden S, Halterman MW. "The post-cardiac arrest syndrome: A case for lung-brain coupling and opportunities for neuroprotection." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2019 Mar 13; :271678X19835552. Epub 2019 Mar 13.

Sims MH, Hodges Shaw M, Gilbertson S, Storch J, Halterman MW. "Legal and ethical issues surrounding the use of crowdsourcing among healthcare providers." Health informatics journal.. 2018 Sep 7; :1460458218796599. Epub 2018 Sep 07.

Buczynski BW, Mai N, Yee M, Allen JL, Prifti L, Cory-Slechta DA, Halterman MW, O'Reilly MA. "Lung-Specific Extracellular Superoxide Dismutase Improves Cognition of Adult Mice Exposed to Neonatal Hyperoxia." Frontiers in medicine.. 2018 5:334. Epub 2018 Dec 10.

Mills BN, Albert GP, Halterman MW. "Expression Profiling of the MAP Kinase Phosphatase Family Reveals a Role for DUSP1 in the Glioblastoma Stem Cell Niche." Cancer microenvironment : official journal of the International Cancer Microenvironment Society.. 2017 Dec; 10(1-3):57-68. Epub 2017 Aug 18.

Mai N, Prifti L, Rininger A, Bazarian H, Halterman MW. "Endotoxemia induces lung-brain coupling and multi-organ injury following cerebral ischemia-reperfusion." Experimental neurology.. 2017 Nov; 297:82-91. Epub 2017 Jul 28.

Pröschel C, Hansen JN, Ali A, Tuttle E, Lacagnina M, Buscaglia G, Halterman MW, Paciorkowski AR. "Epilepsy-causing sequence variations in SIK1 disrupt synaptic activity response gene expression and affect neuronal morphology." European journal of human genetics : EJHG.. 2017 Feb; 25(2):216-221. Epub 2016 Dec 14.

Sims MH, Fagnano M, Halterman JS, Halterman MW. "Provider impressions of the use of a mobile crowdsourcing app in medical practice." Health informatics journal.. 2016 Jun; 22(2):221-31. Epub 2014 Aug 28.

Hansen J, Snow C, Tuttle E, Ghoneim DH, Yang CS, Spencer A, Gunter SA, Smyser CD, Gurnett CA, Shinawi M, Dobyns WB, Wheless J, Halterman MW, Jansen LA, Paschal BM, Paciorkowski AR. "De novo mutations in SIK1 cause a spectrum of developmental epilepsies." American journal of human genetics.. 2015 Apr 2; 96(4):682-90.

Sims MH, Bigham J, Kautz H, Halterman MW. "Crowdsourcing medical expertise in near real time." Journal of hospital medicine.. 2014 Jul; 9(7):451-6. Epub 2014 Apr 17.

Matthews TA, Abel A, Demme C, Sherman T, Pan PW, Halterman MW, Parkkila S, Nehrke K. "Expression of the CHOP-inducible carbonic anhydrase CAVI-b is required for BDNF-mediated protection from hypoxia." Brain research.. 2014 Jan 16; 1543:28-37. Epub 2013 Nov 23.

Rininger A, Dejesus C, Totten A, Wayland A, Halterman MW. "MKP-1 antagonizes C/EBP? activity and lowers the apoptotic threshold after ischemic injury." Cell death and differentiation.. 2012 Oct; 19(10):1634-43. Epub 2012 Apr 20.

Rininger A, Wayland A, Prifti V, Halterman MW. "Assessment of CA1 injury after global ischemia using supervised 2D analyses of nuclear pyknosis." Journal of neuroscience methods.. 2012 Jun 15; 207(2):181-8. Epub 2012 Apr 21.

Segel GB, Halterman MW, Lichtman MA. "The paradox of the neutrophil's role in tissue injury." Journal of leukocyte biology.. 2011 Mar; 89(3):359-72. Epub 2010 Nov 19.

Halterman MW. "An improved method for the study of apoptosis-related genes using the tet-on system." Journal of biomolecular screening.. 2011 Mar; 16(3):332-7. Epub 2011 Feb 18.

Qazi A, Halterman MW, Mi Z, Zhang T, Schor NF. "Chopper is prodeath regardless of the effect of p75ICD on sensitivity to oxidative stress." Oxidative medicine and cellular longevity.. 2011 2011:391659. Epub 2011 Sep 05.

Halterman MW, Gill M, Dejesus C, Ogihara M, Schor NF, Federoff HJ. "The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death." The Journal of biological chemistry.. 2010 Jul 9; 285(28):21329-40. Epub 2010 May 06.

Halterman MW, Giuliano R, Dejesus C, Schor NF. "In-tube transfection improves the efficiency of gene transfer in primary neuronal cultures." Journal of neuroscience methods.. 2009 Mar 15; 177(2):348-54. Epub 2008 Oct 30.

Halterman MW, De Jesus C, Rempe DA, Schor NF, Federoff HJ. "Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons." Molecular and cellular neurosciences.. 2008 Jun; 38(2):125-37. Epub 2008 Feb 13.

Halterman MW, Vates GE, Riggs G. "Teaching NeuroImage: tremor in aqueductal stenosis and response to endoscopic third ventriculostomy." Neurology.. 2007 May 8; 68(19):E29-31.

Halterman MW, Giuliano RE, Bowers WJ, Federoff HJ. "Improved HSV-1 amplicon packaging using virion host shutoff mutants lacking mRNAse activity." The journal of gene medicine.. 2006 Nov; 8(11):1320-8.

Abeysinghe HR, Pollock SJ, Guckert NL, Veyberman Y, Keng P, Halterman M, Federoff HJ, Rosenblatt JP, Wang N. "The role of the THY1 gene in human ovarian cancer suppression based on transfection studies." Cancer genetics and cytogenetics.. 2004 Feb; 149(1):1-10.

Delman KA, Zager JS, Bennett JJ, Malhotra S, Ebright MI, McAuliffe PF, Halterman MW, Federoff HJ, Fong Y. "Efficacy of multiagent herpes simplex virus amplicon-mediated immunotherapy as adjuvant treatment for experimental hepatic cancer." Annals of surgery.. 2002 Sep; 236(3):337-42; discussion 342-3.

Detrait ER, Bowers WJ, Halterman MW, Giuliano RE, Bennice L, Federoff HJ, Richfield EK. "Reporter gene transfer induces apoptosis in primary cortical neurons." Molecular therapy : the journal of the American Society of Gene Therapy.. 2002 Jun; 5(6):723-30.

Carew JF, Kooby DA, Halterman MW, Kim SH, Federoff HJ, Fong Y. "A novel approach to cancer therapy using an oncolytic herpes virus to package amplicons containing cytokine genes." Molecular therapy : the journal of the American Society of Gene Therapy.. 2001 Sep; 4(3):250-6.

Zager JS, Delman KA, Malhotra S, Ebright MI, Bennett JJ, Kates T, Halterman M, Federoff H, Fong Y. "Combination vascular delivery of herpes simplex oncolytic viruses and amplicon mediated cytokine gene transfer is effective therapy for experimental liver cancer." Molecular medicine.. 2001 Aug; 7(8):561-8.

Tolba KA, Bowers WJ, Hilchey SP, Halterman MW, Howard DF, Giuliano RE, Federoff HJ, Rosenblatt JD. "Development of herpes simplex virus-1 amplicon-based immunotherapy for chronic lymphocytic leukemia." Blood.. 2001 Jul 15; 98(2):287-95.

Bowers WJ, Howard DF, Brooks AI, Halterman MW, Federoff HJ. "Expression of vhs and VP16 during HSV-1 helper virus-free amplicon packaging enhances titers." Gene therapy.. 2001 Jan; 8(2):111-20.

Bennett JJ, Kooby DA, Delman K, McAuliffe P, Halterman MW, Federoff H, Fong Y. "Antitumor efficacy of regional oncolytic viral therapy for peritoneally disseminated cancer." Journal of molecular medicine : official organ of the "Gesellschaft Deutscher Naturforscher und A?rzte".. 2000 78(3):166-74.

Van de Water TR, Staecker H, Halterman MW, Federoff HJ. "Gene therapy in the inner ear. Mechanisms and clinical implications." Annals of the New York Academy of Sciences.. 1999 Nov 28; 884:345-60.

Halterman MW, Federoff HJ. "HIF-1alpha and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia." Experimental neurology.. 1999 Sep; 159(1):65-72.

D'Angelica M, Tung C, Allen P, Halterman M, Delman K, Delohery T, Klimstra D, Brownlee M, Federoff H, Fong Y. "Herpes simplex virus (HSV)-mediated ICAM-1 gene transfer abrogates tumorigenicity and induces anti-tumor immunity." Molecular medicine.. 1999 Sep; 5(9):606-16.

Halterman MW, Miller CC, Federoff HJ. "Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1999 Aug 15; 19(16):6818-24.

Kooby DA, Carew JF, Halterman MW, Mack JE, Bertino JR, Blumgart LH, Federoff HJ, Fong Y. "Oncolytic viral therapy for human colorectal cancer and liver metastases using a multi-mutated herpes simplex virus type-1 (G207)." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 1999 Aug; 13(11):1325-34.

Carew JF, Kooby DA, Halterman MW, Federoff HJ, Fong Y. "Selective infection and cytolysis of human head and neck squamous cell carcinoma with sparing of normal mucosa by a cytotoxic herpes simplex virus type 1 (G207)." Human gene therapy.. 1999 Jul 1; 10(10):1599-606.

White SM, Renda M, Nam NY, Klimatcheva E, Zhu Y, Fisk J, Halterman M, Rimel BJ, Federoff H, Pandya S, Rosenblatt JD, Planelles V. "Lentivirus vectors using human and simian immunodeficiency virus elements." Journal of virology.. 1999 Apr; 73(4):2832-40.

Brooks AI, Halterman MW, Federoff HJ. "Focal hippocampal gain of NGF function elicits specific septal cholinergic reorganization." Neuroreport.. 1999 Feb 5; 10(2):337-44.

Kutubuddin M, Federoff HJ, Challita-Eid PM, Halterman M, Day B, Atkinson M, Planelles V, Rosenblatt JD. "Eradication of pre-established lymphoma using herpes simplex virus amplicon vectors." Blood.. 1999 Jan 15; 93(2):643-54.

D'Angelica M, Karpoff H, Halterman M, Ellis J, Klimstra D, Edelstein D, Brownlee M, Federoff H, Fong Y. "In vivo interleukin-2 gene therapy of established tumors with herpes simplex amplicon vectors." Cancer immunology, immunotherapy : CII.. 1999 Jan; 47(5):265-71.

Carew JF, Federoff H, Halterman M, Kraus DH, Savage H, Sacks PG, Schantz SP, Shah JP, Fong Y. "Efficient gene transfer to human squamous cell carcinomas by the herpes simplex virus type 1 amplicon vector." American journal of surgery.. 1998 Nov; 176(5):404-8.

Parry S, Holder J, Halterman MW, Weitzman MD, Davis AR, Federoff H, Strauss JF. "Transduction of human trophoblastic cells by replication-deficient recombinant viral vectors. Promoting cellular differentiation affects virus entry." The American journal of pathology.. 1998 Jun; 152(6):1521-9.

Brooks AI, Halterman MW, Chadwick CA, Davidson BL, Haak-Frendscho M, Radel C, Porter C, Federoff HJ. "Reproducible and efficient murine CNS gene delivery using a microprocessor-controlled injector." Journal of neuroscience methods.. 1998 Apr 30; 80(2):137-47.

Federoff HJ, Halterman MW, Brooks AI. "Use of the herpes amplicon system as a vehicle for somatic gene transfer." Advanced drug delivery reviews.. 1997 Aug 11; 27(1):29-39.