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Laura M. Calvi, M.D.


Showing all 70 journal articles & 0 books available

Journal Articles

Zhang H, Liesveld JL, Calvi LM, Lipe BC, Xing L, Becker MW, Schwarz EM, Yeh SA. "The roles of bone remodeling in normal hematopoiesis and age-related hematological malignancies." Bone research.. 2023 Mar 14; 11(1):15. Epub 2023 Mar 14.

Lynch OF, Calvi LM. "Immune Dysfunction, Cytokine Disruption, and Stromal Changes in Myelodysplastic Syndrome: A Review." Cells.. 2022 Feb 8; 11(3)Epub 2022 Feb 08.

Ruffolo LI, Jackson KM, Kuhlers PC, Dale BS, Figueroa Guilliani NM, Ullman NA, Burchard PR, Qin SS, Juviler PG, Keilson JM, Morrison AB, Georger M, Jewell R, Calvi LM, Nywening TM, O'Dell MR, Hezel AF, De Las Casas L, Lesinski GB, Yeh JJ, Hernandez-Alejandro R, Belt BA, Linehan DC. "GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity." Gut.. 2021 Aug 19; Epub 2021 Aug 19.

Saunders J, Niswander LM, McGrath KE, Koniski A, Catherman SC, Ture SK, Medhora M, Kingsley PD, Calvi LM, Williams JP, Morrell CN, Palis J. "Long-acting PGE2 and Lisinopril Mitigate H-ARS." Radiation research.. 2021 Jun 21; Epub 2021 Jun 21.

Ackun-Farmmer MA, Soto CA, Lesch ML, Byun D, Yang L, Calvi LM, Benoit DSW, Frisch BJ. "Reduction of leukemic burden via bone-targeted nanoparticle delivery of an inhibitor of C-chemokine (C-C motif) ligand 3 (CCL3) signaling." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2021 Apr; 35(4):e21402.

Seyfried AN, McCabe A, Smith JNP, Calvi LM, MacNamara KC. "CCR5 maintains macrophages in the bone marrow and drives hematopoietic failure in a mouse model of severe aplastic anemia." Leukemia.. 2021 Mar 20; Epub 2021 Mar 20.

Calvi LM. "FGF-23: a novel actor in stem cell mobilization." Blood.. 2021 Mar 18; 137(11):1434-1436.

Calvi LM. "Improved in vivo Experimental Screening Identifies an Anabolic Analog of 1,25 Dihydroxyvitamin D3 With Minimal Bone Resorption Activity." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2020 Jan 6; Epub 2020 Jan 06.

Calvi LM, Li AJ, Becker MW. "What is the role of the microenvironment in MDS?" Best practice & research. Clinical haematology.. 2019 Dec; 32(4):101113. Epub 2019 Oct 28.

Azadniv M, Myers JR, McMurray HR, Guo N, Rock P, Coppage ML, Ashton J, Becker MW, Calvi LM, Liesveld JL. "Bone marrow mesenchymal stromal cells from acute myelogenous leukemia patients demonstrate adipogenic differentiation propensity with implications for leukemia cell support." Leukemia.. 2019 Sep 6; Epub 2019 Sep 06.

Calvi LM, Frisch BJ, Kingsley PD, Koniski AD, Love TM, Williams JP, Palis J. "Acute and late effects of combined internal and external radiation exposures on the hematopoietic system." International journal of radiation biology.. 2019 Jul 30; :1-15. Epub 2019 Jul 30.

Banerjee T, Calvi LM, Becker MW, Liesveld JL. "Flaming and fanning: The Spectrum of inflammatory influences in myelodysplastic syndromes." Blood reviews.. 2019 Jul; 36:57-69. Epub 2019 Apr 18.

Calvi LM, Hofbauer LC. "A Novel Strategy for Repairing Multiple Myeloma Bone Lesions: Lessons From Murine Models." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2019 May; 34(5):781-782. Epub 2019 May 09.

Frisch BJ, Hoffman CM, Latchney SE, LaMere MW, Myers J, Ashton J, Li AJ, Saunders J, Palis J, Perkins AS, McCabe A, Smith JN, McGrath KE, Rivera-Escalera F, McDavid A, Liesveld JL, Korshunov VA, Elliott MR, MacNamara KC, Becker MW, Calvi LM. "Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B." JCI insight.. 2019 Apr 18; 5Epub 2019 Apr 18.

Ayoub E, Wilson MP, McGrath KE, Li AJ, Frisch BJ, Palis J, Calvi LM, Zhang Y, Perkins AS. "EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription." Nature communications.. 2018 Oct 12; 9(1):4239. Epub 2018 Oct 12.

Staversky RJ, Byun DK, Georger MA, Zaffuto BJ, Goodman A, Becker MW, Calvi LM, Frisch BJ. "The Chemokine CCL3 Regulates Myeloid Differentiation and Hematopoietic Stem Cell Numbers." Scientific reports.. 2018 Oct 2; 8(1):14691. Epub 2018 Oct 02.

Hoffman CM, Han J, Calvi LM. "Impact of aging on bone, marrow and their interactions." Bone.. 2018 Jul 16; Epub 2018 Jul 16.

Li AJ, Calvi LM. "The microenvironment in myelodysplastic syndromes: Niche-mediated disease initiation and progression." Experimental hematology.. 2017 Nov; 55:3-18. Epub 2017 Aug 18.

Lawal RA, Zhou X, Batey K, Hoffman CM, Georger MA, Radtke F, Hilton MJ, Xing L, Frisch BJ, Calvi LM. "The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2017 Jun; 32(6):1320-1331. Epub 2017 Mar 09.

Oleksyn D, Zhao J, Vosoughi A, Zhao JC, Misra R, Pentland AP, Ryan D, Anolik J, Ritchlin C, Looney J, Anandarajah AP, Schwartz G, Calvi LM, Georger M, Mohan C, Sanz I, Chen L. "PKK deficiency in B cells prevents lupus development in Sle lupus mice." Immunology letters.. 2017 May; 185:1-11. Epub 2017 Mar 06.

Latchney SE, Calvi LM. "The aging hematopoietic stem cell niche: Phenotypic and functional changes and mechanisms that contribute to hematopoietic aging." Seminars in hematology.. 2017 Jan; 54(1):25-32. Epub 2016 Oct 19.

Lee CC, Kimmell KT, Lalonde A, Salzman P, Miller MC, Calvi LM, Manuylova E, Shafiq I, Edward Vates G. "Geographic variation in cost of care for pituitary tumor surgery." Pituitary.. 2016 Oct; 19(5):515-21.

Balderman SR, Li AJ, Hoffman CM, Frisch BJ, Goodman AN, LaMere MW, Georger MA, Evans AG, Liesveld JL, Becker MW, Calvi LM. "Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome." Blood.. 2016 Feb 4; 127(5):616-25. Epub 2015 Dec 04.

Manuylova E, Calvi LM, Hastings C, Vates GE, Johnson MD, Cave WT, Shafiq I. "Late presentation of acromegaly in medically controlled prolactinoma patients." Endocrinology, diabetes & metabolism case reports.. 2016 2016Epub 2016 Oct 17.

Calvi LM, Link DC. "The hematopoietic stem cell niche in homeostasis and disease." Blood.. 2015 Nov 26; 126(22):2443-51. Epub 2015 Oct 14.

Manuylova E, Calvi LM, Vates GE, Hastings C, Shafiq I. "MORNING SERUM CORTISOL LEVEL AFTER TRANSSPHENOIDAL SURGERY FOR PITUITARY ADENOMA PREDICTS HYPOTHALAMIC-PITUITARY-ADRENAL FUNCTION DESPITE INTRAOPERATIVE DEXAMETHASONE USE." Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.. 2015 Aug; 21(8):897-902. Epub 2015 Jun 29.

Hutchinson K, Jahangiri S, Calvi LM, Barr P, Friedberg JW, Kelly JL. "Impact of dietary supplements, obesity and treatment initiation on serum vitamin D levels in patients with lymphoma." Leukemia & lymphoma.. 2015 Feb; 56(2):508-11. Epub 2014 Jul 15.

Evans AG, Calvi LM. "Notch signaling in the malignant bone marrow microenvironment: implications for a niche-based model of oncogenesis." Annals of the New York Academy of Sciences.. 2015 Jan; 1335:63-77. Epub 2014 Oct 28.

Sivagnanalingam U, Balys M, Eberhardt A, Wang N, Myers JR, Ashton JM, Becker MW, Calvi LM, Mendler JH. "Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia." PloS one.. 2015 10(7):e0132375. Epub 2015 Jul 15.

Balderman SR, Calvi LM. "Biology of BM failure syndromes: role of microenvironment and niches." Hematology. 2014 Dec 5; 2014(1):71-6. Epub 2014 Nov 18.

Hoffman CM, Calvi LM. "Minireview: complexity of hematopoietic stem cell regulation in the bone marrow microenvironment." Molecular endocrinology.. 2014 Oct; 28(10):1592-601. Epub 2014 Aug 01.

Calvi LM, Link DC. "Cellular complexity of the bone marrow hematopoietic stem cell niche." Calcified tissue international.. 2014 Jan; 94(1):112-24. Epub 2013 Oct 08.

Frisch BJ, Calvi LM. "Hematopoietic stem cell cultures and assays." Methods in molecular biology.. 2014 1130:315-324.

Frisch BJ, Calvi LM. "Osteoblasts as leukemia-initiating cells." BoneKEy reports. 2014 3:572. Epub 2014 Sep 03.

Li JY, Adams J, Calvi LM, Lane TF, Weitzmann MN, Pacifici R. "Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B." Blood.. 2013 Oct 3; 122(14):2346-57. Epub 2013 Aug 16.

Calvi LM. "Osteolineage cells and regulation of the hematopoietic stem cell." Best practice & research. Clinical haematology.. 2013 Sep; 26(3):249-52. Epub 2013 Oct 16.

Smith JN, Calvi LM. "Concise review: Current concepts in bone marrow microenvironmental regulation of hematopoietic stem and progenitor cells." Stem cells.. 2013 Jun; 31(6):1044-50.

Yeaney GA, Brathwaite JM, Dashnaw ML, Vates GE, Calvi LM. "Pituitary adenoma with mucin cells in a man with an unusual presentation of Carney complex." Endocrine pathology.. 2013 Jun; 24(2):106-9.

Dhillon RS, Xie C, Tyler W, Calvi LM, Awad HA, Zuscik MJ, O'Keefe RJ, Schwarz EM. "PTH-enhanced structural allograft healing is associated with decreased angiopoietin-2-mediated arteriogenesis, mast cell accumulation, and fibrosis." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2013 Mar; 28(3):586-97.

Porter RL, Georger M, Bromberg O, McGrath KE, Frisch BJ, Becker MW, Calvi LM. "Prostaglandin E2 increases hematopoietic stem cell survival and accelerates hematopoietic recovery after radiation injury." Stem cells.. 2013 Feb; 31(2):372-83.

Steinman RA, De Castro IO, Shrayyef M, Chengazi V, Giampoli E, Van Der Sloot P, Calvi LM, Wittlin SD, Hammes SR, Hou R. "Two cases of malignant struma ovarii with metastasis to pelvic bone." Gynecologic and obstetric investigation.. 2013 75(2):139-44. Epub 2013 Feb 06.

Li JY, Adams J, Calvi LM, Lane TF, Dipaolo R, Weitzmann MN, Pacifici R. "PTH expands short-term murine hemopoietic stem cells through T cells." Blood.. 2012 Nov 22; 120(22):4352-62. Epub 2012 Sep 05.

Bromberg O, Frisch BJ, Weber JM, Porter RL, Civitelli R, Calvi LM. "Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells." Blood.. 2012 Jul 12; 120(2):303-13. Epub 2012 May 17.

Calvi LM, Bromberg O, Rhee Y, Weber JM, Smith JN, Basil M, Frisch BJ, Bellido T. "Osteoblastic expansion induced by parathyroid hormone receptor signaling in murine osteocytes is not sufficient to increase hematopoietic stem cells." Blood.. 2012 Mar 15; 119(11):2489-99. Epub 2012 Jan 18.

Frisch BJ, Ashton JM, Xing L, Becker MW, Jordan CT, Calvi LM. "Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia." Blood.. 2012 Jan 12; 119(2):540-50. Epub 2011 Sep 28.

Loiselle AE, Frisch BJ, Wolenski M, Jacobson JA, Calvi LM, Schwarz EM, Awad HA, O'Keefe RJ. "Bone marrow-derived matrix metalloproteinase-9 is associated with fibrous adhesion formation after murine flexor tendon injury." PloS one.. 2012 7(7):e40602. Epub 2012 Jul 11.

Lawal RA, Calvi LM. "The niche as a target for hematopoietic manipulation and regeneration." Tissue engineering. Part B, Reviews.. 2011 Dec; 17(6):415-22. Epub 2011 Sep 27.

Calvi LM. "Agrin complicates the niche." Blood.. 2011 Sep 8; 118(10):2641-2.

Calvi L, Daniels GH. "Acute thyrotoxicosis secondary to destructive thyroiditis associated with cardiac catheterization contrast dye." Thyroid : official journal of the American Thyroid Association.. 2011 Apr; 21(4):443-9.

Smith JN, Calvi LM. "Regulatory Interactions in the Bone Marrow Microenvironment." IBMS boneKEy. 2011 8(2):96-111.

Kelly JL, Friedberg JW, Calvi LM, van Wijngaarden E, Fisher SG. "A case-control study of ultraviolet radiation exposure, vitamin D, and lymphoma risk in adults." Cancer causes & control : CCC.. 2010 Aug; 21(8):1265-75. Epub 2010 Apr 07.

Weber JM, Calvi LM. "Notch signaling and the bone marrow hematopoietic stem cell niche." Bone.. 2010 Feb; 46(2):281-5. Epub 2009 Aug 11.

Frisch BJ, Porter RL, Gigliotti BJ, Olm-Shipman AJ, Weber JM, O'Keefe RJ, Jordan CT, Calvi LM. "In vivo prostaglandin E2 treatment alters the bone marrow microenvironment and preferentially expands short-term hematopoietic stem cells." Blood.. 2009 Nov 5; 114(19):4054-63. Epub 2009 Sep 02.

Kelly JL, Friedberg JW, Calvi LM, van Wijngaarden E, Fisher SG. "Vitamin D and non-Hodgkin lymphoma risk in adults: a review." Cancer investigation.. 2009 Nov; 27(9):942-51.

Porter RL, Calvi LM. "Key endothelial signals required for hematopoietic recovery." Cell stem cell.. 2009 Mar 6; 4(3):187-8.

Coleman RE, Guise TA, Lipton A, Roodman GD, Berenson JR, Body JJ, Boyce BF, Calvi LM, Hadji P, McCloskey EV, Saad F, Smith MR, Suva LJ, Taichman RS, Vessella RL, Weilbaecher KN. "Advancing treatment for metastatic bone cancer: consensus recommendations from the Second Cambridge Conference." Clinical cancer research : an official journal of the American Association for Cancer Research.. 2008 Oct 15; 14(20):6387-95.

Frisch BJ, Porter RL, Calvi LM. "Hematopoietic niche and bone meet." Current opinion in supportive and palliative care.. 2008 Sep; 2(3):211-7.

Calvi LM, Bushinsky DA. "When is it appropriate to order an ionized calcium?" Journal of the American Society of Nephrology : JASN.. 2008 Jul; 19(7):1257-60. Epub 2008 Jan 23.

Proulx ST, Kwok E, You Z, Papuga MO, Beck CA, Shealy DJ, Calvi LM, Ritchlin CT, Awad HA, Boyce BF, Xing L, Schwarz EM. "Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging." Arthritis and rheumatism.. 2008 Jul; 58(7):2019-29.

Porter RL, Calvi LM. "Communications between bone cells and hematopoietic stem cells." Archives of biochemistry and biophysics.. 2008 May 15; 473(2):193-200. Epub 2008 Apr 07.

Adams GB, Martin RP, Alley IR, Chabner KT, Cohen KS, Calvi LM, Kronenberg HM, Scadden DT. "Therapeutic targeting of a stem cell niche." Nature biotechnology.. 2007 Feb; 25(2):238-43. Epub 2007 Jan 21.

Weber JM, Forsythe SR, Christianson CA, Frisch BJ, Gigliotti BJ, Jordan CT, Milner LA, Guzman ML, Calvi LM. "Parathyroid hormone stimulates expression of the Notch ligand Jagged1 in osteoblastic cells." Bone.. 2006 Sep; 39(3):485-93. Epub 2006 May 02.

Calvi LM. "Osteoblastic activation in the hematopoietic stem cell niche." Annals of the New York Academy of Sciences.. 2006 Apr; 1068:477-88.

Stier S, Ko Y, Forkert R, Lutz C, Neuhaus T, Grünewald E, Cheng T, Dombkowski D, Calvi LM, Rittling SR, Scadden DT. "Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size." The Journal of experimental medicine.. 2005 Jun 6; 201(11):1781-91. Epub 2005 May 31.

Kuznetsov SA, Riminucci M, Ziran N, Tsutsui TW, Corsi A, Calvi L, Kronenberg HM, Schipani E, Robey PG, Bianco P. "The interplay of osteogenesis and hematopoiesis: expression of a constitutively active PTH/PTHrP receptor in osteogenic cells perturbs the establishment of hematopoiesis in bone and of skeletal stem cells in the bone marrow." The Journal of cell biology.. 2004 Dec 20; 167(6):1113-22.

Calvi LM, Shin HI, Knight MC, Weber JM, Young MF, Giovannetti A, Schipani E. "Constitutively active PTH/PTHrP receptor in odontoblasts alters odontoblast and ameloblast function and maturation." Mechanisms of development.. 2004 Apr; 121(4):397-408.

Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, Martin RP, Schipani E, Divieti P, Bringhurst FR, Milner LA, Kronenberg HM, Scadden DT. "Osteoblastic cells regulate the haematopoietic stem cell niche." Nature.. 2003 Oct 23; 425(6960):841-6.

Chiusaroli R, Maier A, Knight MC, Byrne M, Calvi LM, Baron R, Krane SM, Schipani E. "Collagenase cleavage of type I collagen is essential for both basal and parathyroid hormone (PTH)/PTH-related peptide receptor-induced osteoclast activation and has differential effects on discrete bone compartments." Endocrinology.. 2003 Sep; 144(9):4106-16.

Calvi LM, Sims NA, Hunzelman JL, Knight MC, Giovannetti A, Saxton JM, Kronenberg HM, Baron R, Schipani E. "Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone." The Journal of clinical investigation.. 2001 Feb; 107(3):277-86.

Calvi LM, Schipani E. "The PTH/PTHrP receptor in Jansen's metaphyseal chondrodysplasia." Journal of endocrinological investigation.. 2000 Sep; 23(8):545-54.