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Stephen Dewhurst, Ph.D.


Showing all 202 journal articles & 0 books available

Journal Articles

Zhou T, Gilliam NJ, Li S, Spandau S, Osborn RM, Connor S, Anderson CS, Mariani TJ, Thakar J, Dewhurst S, Mathews DH, Huang L, Sun Y. "Generation and Functional Analysis of Defective Viral Genomes during SARS-CoV-2 Infection." mBio.. 2023 Apr 19; :e0025023. Epub 2023 Apr 19.

Osborn RM, Leach J, Zanche M, Ashton JM, Chu C, Thakar J, Dewhurst S, Rosenberger S, Pavelka M, Pryhuber GS, Mariani TJ, Anderson CS. "Preparation of noninfectious scRNAseq samples from SARS-CoV-2-infected epithelial cells." PloS one.. 2023 18(2):e0281898. Epub 2023 Feb 24.

Zhou T, Gilliam NJ, Li S, Spaudau S, Osborn RM, Anderson CS, Mariani TJ, Thakar J, Dewhurst S, Mathews DH, Huang L, Sun Y. "Generation and functional analysis of defective viral genomes during SARS-CoV-2 infection." bioRxiv : the preprint server for biology.. 2022 Sep 23; Epub 2022 Sep 23.

Nogales A, Steel J, Liu WC, Lowen AC, Rodriguez L, Chiem K, Cox A, García-Sastre A, Albrecht RA, Dewhurst S, Martínez-Sobrido L. "Mutation L319Q in the PB1 Polymerase Subunit Improves Attenuation of a Candidate Live-Attenuated Influenza A Virus Vaccine." Microbiology spectrum.. 2022 May 18; :e0007822. Epub 2022 May 18.

Raymonda MH, Ciesla JH, Monaghan M, Leach J, Asantewaa G, Smorodintsev-Schiller LA, Lutz MM, Schafer XL, Takimoto T, Dewhurst S, Munger J, Harris IS. "Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro." Virology.. 2021 Nov 27; 566:60-68. Epub 2021 Nov 27.

Sherby MR, Kalb LG, Coller RJ, DeMuri GP, Butteris S, Foxe JJ, Zand MS, Freedman EG, Dewhurst S, Newland JG, Gurnett CA. "Supporting COVID-19 School Safety for Children With Disabilities and Medical Complexity." Pediatrics.. 2021 Nov 4; Epub 2021 Nov 04.

Chojnacki M, Dobrotka C, Osborn R, Johnson W, Young M, Meyer B, Laskey E, Wozniak RAF, Dewhurst S, Dunman PM. "Evaluating the Antimicrobial Properties of Commercial Hand Sanitizers." mSphere.. 2021 Mar 3; 6(2)Epub 2021 Mar 03.

Cox A, Schmierer J, D'Angelo J, Smith A, Levenson D, Treanor J, Kim B, Dewhurst S. "A Mutated PB1 Residue 319 Synergizes with the PB2 N265S Mutation of the Live Attenuated Influenza Vaccine to Convey Temperature Sensitivity." Viruses.. 2020 Oct 31; 12(11)Epub 2020 Oct 31.

Simpson SR, Singh MV, Dewhurst S, Schifitto G, Maggirwar SB. "Platelets function as an acute viral reservoir during HIV-1 infection by harboring virus and T-cell complex formation." Blood advances.. 2020 Sep 22; 4(18):4512-4521.

Piekna-Przybylska D, Bambara RA, Maggirwar SB, Dewhurst S. "G-quadruplex ligands targeting telomeres do not inhibit HIV promoter activity and cooperate with latency reversing agents in killing latently infected cells." Cell cycle.. 2020 Aug 17; :1-16. Epub 2020 Aug 17.

Ma Q, Schifitto G, Venuto C, Ocque A, Dewhurst S, Morse GD, Aalinkeel R, Schwartz SA, Mahajan SD. "Effect of Dolutegravir and Sertraline on the Blood Brain Barrier (BBB)." Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.. 2020 Mar; 15(1):7-9. Epub 2020 Jan 15.

Smith A, Rodriguez L, El Ghouayel M, Nogales A, Chamberlain JM, Sortino K, Reilly E, Feng C, Topham DJ, Martínez-Sobrido L, Dewhurst S. "A Live Attenuated Influenza Vaccine Elicits Enhanced Heterologous Protection When the Internal Genes of the Vaccine Are Matched to Those of the Challenge Virus." Journal of virology.. 2020 Jan 31; 94(4)Epub 2020 Jan 31.

Rodriguez L, Blanco-Lobo P, Reilly EC, Maehigashi T, Nogales A, Smith A, Topham DJ, Dewhurst S, Kim B, Martínez-Sobrido L. "Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines." Viruses.. 2019 Oct 10; 11(10)Epub 2019 Oct 10.

Chamberlain J, Sortino K, Sethna P, Bae A, Lanier R, Bambara RA, Dewhurst S. "Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via Both Non-Obligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus." Antimicrobial agents and chemotherapy.. 2018 Nov 5; Epub 2018 Nov 05.

Mathew E, Zhu H, Connelly SM, Sullivan MA, Brewer MG, Piepenbrink MS, Kobie JJ, Dewhurst S, Dumont ME. "Display of the HIV envelope protein at the yeast cell surface for immunogen development." PloS one.. 2018 13(10):e0205756. Epub 2018 Oct 18.

Sheik DA, Dewhurst S, Yang J. "Natural Seminal Amyloids as Targets for Development of Synthetic Inhibitors of HIV Transmission." Accounts of chemical research.. 2017 Sep 19; 50(9):2159-2166. Epub 2017 Aug 15.

Hilimire TA, Chamberlain JM, Anokhina V, Bennett RP, Swart O, Myers JR, Ashton JM, Stewart RA, Featherston AL, Gates K, Helms ED, Smith HC, Dewhurst S, Miller BL. "HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi-Drug-Resistant HIV in Human Cells." ACS chemical biology.. 2017 Jun 16; 12(6):1674-1682. Epub 2017 May 05.

Sheik DA, Chamberlain JM, Brooks L, Clark M, Kim YH, Leriche G, Kubiak CP, Dewhurst S, Yang J. "Hydrophobic Nanoparticles Reduce the ?-Sheet Content of SEVI Amyloid Fibrils and Inhibit SEVI-Enhanced HIV Infectivity." Langmuir : the ACS journal of surfaces and colloids.. 2017 Mar 14; 33(10):2596-2602. Epub 2017 Mar 01.

Brewer MG, DiPiazza A, Acklin J, Feng C, Sant AJ, Dewhurst S. "Nanoparticles decorated with viral antigens are more immunogenic at low surface density." Vaccine.. 2017 Feb 1; 35(5):774-781. Epub 2017 Jan 03.

Buckley G, Smith S, DeCaro J, Barnett S, Dewhurst S. "Building community for deaf scientists." Science.. 2017 Jan 20; 355(6322):255.

Mattiacio JL, Brewer M, Dewhurst S. "Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform." Methods in molecular biology.. 2017 1581:245-253.

Blanchard C, Brooks L, Beckley A, Colquhoun J, Dewhurst S, Dunman PM. "Neomycin Sulfate Improves the Antimicrobial Activity of Mupirocin-Based Antibacterial Ointments." Antimicrobial agents and chemotherapy.. 2016 Feb; 60(2):862-72. Epub 2015 Nov 23.

Nishimura C, Polesskaya O, Dewhurst S, Silva JN. "Quantification of Cerebral Vascular Architecture using Two-photon Microscopy in a Mouse Model of HIV-induced Neuroinflammation." Journal of visualized experiments : JoVE.. 2016 Jan 12; (107):e53582. Epub 2016 Jan 12.

Blanchard C, Brooks L, Ebsworth-Mojica K, Didione L, Wucher B, Dewhurst S, Krysan D, Dunman PM, Wozniak RA. "Zinc Pyrithione Improves the Antibacterial Activity of Silver Sulfadiazine Ointment." mSphere.. 2016 1(5)Epub 2016 Sep 14.

Cox A, Dewhurst S. "A Single Mutation at PB1 Residue 319 Dramatically Increases the Safety of PR8 Live Attenuated Influenza Vaccine in a Murine Model without Compromising Vaccine Efficacy." Journal of virology.. 2015 Dec 16; 90(5):2702-5. Epub 2015 Dec 16.

Puccini JM, Marker DF, Fitzgerald T, Barbieri J, Kim CS, Miller-Rhodes P, Lu SM, Dewhurst S, Gelbard HA. "Leucine-rich repeat kinase 2 modulates neuroinflammation and neurotoxicity in models of human immunodeficiency virus 1-associated neurocognitive disorders." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2015 Apr 1; 35(13):5271-83.

Cox A, Baker SF, Nogales A, Martínez-Sobrido L, Dewhurst S. "Development of a mouse-adapted live attenuated influenza virus that permits in vivo analysis of enhancements to the safety of live attenuated influenza virus vaccine." Journal of virology.. 2015 Mar; 89(6):3421-6. Epub 2014 Dec 31.

Sheik DA, Brooks L, Frantzen K, Dewhurst S, Yang J. "Inhibition of the enhancement of infection of human immunodeficiency virus by semen-derived enhancer of virus infection using amyloid-targeting polymeric nanoparticles." ACS nano.. 2015 Feb 24; 9(2):1829-1836. Epub 2015 Feb 02.

Ying B, Tollefson AE, Spencer JF, Balakrishnan L, Dewhurst S, Capella C, Buller RM, Toth K, Wold WS. "Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters." Antimicrobial agents and chemotherapy.. 2014 Dec; 58(12):7171-81. Epub 2014 Sep 15.

Silva JN, Polesskaya O, Wei HS, Rasheed IY, Chamberlain JM, Nishimura C, Feng C, Dewhurst S. "Chronic central nervous system expression of HIV-1 Tat leads to accelerated rarefaction of neocortical capillaries and loss of red blood cell velocity heterogeneity." Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2014 Oct; 21(7):664-76.

Nogales A, Baker SF, Ortiz-Riaño E, Dewhurst S, Topham DJ, Martínez-Sobrido L. "Influenza A virus attenuation by codon deoptimization of the NS gene for vaccine development." Journal of virology.. 2014 Sep; 88(18):10525-40. Epub 2014 Jun 25.

Polesskaya O, Wong C, Lebron L, Chamberlain JM, Gelbard HA, Goodfellow V, Kim M, Daiss JL, Dewhurst S. "MLK3 regulates fMLP-stimulated neutrophil motility." Molecular immunology.. 2014 Apr; 58(2):214-22. Epub 2014 Jan 03.

Domm W, Brewer M, Baker SF, Feng C, Martínez-Sobrido L, Treanor J, Dewhurst S. "Use of bacteriophage particles displaying influenza virus hemagglutinin for the detection of hemagglutination-inhibition antibodies." Journal of virological methods.. 2014 Mar; 197:47-50. Epub 2013 Dec 06.

Lewis CA, Dewhurst S, McMahon JM, Bunce CA, Keefer MC, Alio AP. "Theoretical model of critical issues in informed consent in HIV vaccine trials." AIDS care.. 2014 26(11):1452-60. Epub 2014 May 28.

Rhoo KH, Granger M, Sur J, Feng C, Gelbard HA, Dewhurst S, Polesskaya O. "Pharmacologic inhibition of MLK3 kinase activity blocks the in vitro migratory capacity of breast cancer cells but has no effect on breast cancer brain metastasis in a mouse xenograft model." PloS one.. 2014 9(9):e108487. Epub 2014 Sep 29.

Easterhoff D, Dimaio JT, Liyanage W, Lo CW, Bae W, Doran TM, Smrcka A, Nilsson BL, Dewhurst S. "Fluorescence detection of cationic amyloid fibrils in human semen." Bioorganic & medicinal chemistry letters.. 2013 Sep 15; 23(18):5199-202. Epub 2013 Jul 08.

Lu N, Silva J, Gu Y, Gerber S, Wu H, Gelbard H, Dewhurst S, Miao H. "Directional Histogram Ratio at Random Probes: A Local Thresholding Criterion for Capillary Images." Pattern recognition. 2013 Jul 1; 46(7):1933-1948. Epub 2013 Jan 18.

Marker DF, Tremblay ME, Puccini JM, Barbieri J, Gantz Marker MA, Loweth CJ, Muly EC, Lu SM, Goodfellow VS, Dewhurst S, Gelbard HA. "The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2013 Jun 12; 33(24):9998-10010.

Easterhoff D, Ontiveros F, Brooks LR, Kim Y, Ross B, Silva JN, Olsen JS, Feng C, Hardy DJ, Dunman PM, Dewhurst S. "Semen-derived enhancer of viral infection (SEVI) binds bacteria, enhances bacterial phagocytosis by macrophages, and can protect against vaginal infection by a sexually transmitted bacterial pathogen." Antimicrobial agents and chemotherapy.. 2013 Jun; 57(6):2443-50. Epub 2013 Mar 18.

Arany S, Benoit DS, Dewhurst S, Ovitt CE. "Nanoparticle-mediated gene silencing confers radioprotection to salivary glands in vivo." Molecular therapy : the journal of the American Society of Gene Therapy.. 2013 Jun; 21(6):1182-94. Epub 2013 Mar 19.

Ma Q, Gelbard HA, Maggirwar SB, Dewhurst S, Gendelman HE, Peterson DR, Difrancesco R, Hochreiter JS, Morse GD, Schifitto G. "Pharmacokinetic interactions of CEP-1347 and atazanavir in HIV-infected patients." Journal of neurovirology.. 2013 Jun; 19(3):254-60. Epub 2013 Jun 05.

Sullivan MA, Brooks LR, Weidenborner P, Domm W, Mattiacio J, Xu Q, Tiberio M, Wentworth T, Kobie J, Bryk P, Zheng B, Murphy M, Sanz I, Dewhurst S. "Anti-idiotypic monobodies derived from a fibronectin scaffold." Biochemistry.. 2013 Mar 12; 52(10):1802-13. Epub 2013 Mar 01.

Mapstone M, Hilton TN, Yang H, Guido JJ, Luque AE, Hall WJ, Dewhurst S, Shah K. "Poor Aerobic Fitness May Contribute to Cognitive Decline in HIV-infected Older Adults." Aging and disease.. 2013 4(6):311-9. Epub 2013 Aug 27.

Alcéna DC, Kobie JJ, Kaminski DA, Rosenberg AF, Mattiacio JL, Brewer M, Dewhurst S, Dykes C, Jin X, Keefer MC, Sanz I. "9G4+ antibodies isolated from HIV-infected patients neutralize HIV-1 and have distinct autoreactivity profiles." PloS one.. 2013 8(12):e85098. Epub 2013 Dec 26.

Silva J, Polesskaya O, Knight W, Zheng JT, Granger M, Lopez T, Ontiveros F, Feng C, Yan C, Kasischke KA, Dewhurst S. "Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5." Journal of neuroinflammation.. 2012 Nov 20; 9:253. Epub 2012 Nov 20.

Capella C, Beltejar MJ, Brown C, Fong V, Daddacha W, Kim B, Dewhurst S. "Selective modification of adenovirus replication can be achieved through rational mutagenesis of the adenovirus type 5 DNA polymerase." Journal of virology.. 2012 Oct; 86(19):10484-93. Epub 2012 Jul 18.

Arany S, Xu Q, Hernady E, Benoit DS, Dewhurst S, Ovitt CE. "Pro-apoptotic gene knockdown mediated by nanocomplexed siRNA reduces radiation damage in primary salivary gland cultures." Journal of cellular biochemistry.. 2012 Jun; 113(6):1955-65.

Olsen JS, Dimaio JT, Doran TM, Brown C, Nilsson BL, Dewhurst S. "Seminal plasma accelerates semen-derived enhancer of viral infection (SEVI) fibril formation by the prostatic acid phosphatase (PAP248-286) peptide." The Journal of biological chemistry.. 2012 Apr 6; 287(15):11842-9. Epub 2012 Feb 21.

Polesskaya O, Sun A, Salahura G, Silva JN, Dewhurst S, Kasischke K. "Detection of microregional hypoxia in mouse cerebral cortex by two-photon imaging of endogenous NADH fluorescence." Journal of visualized experiments : JoVE.. 2012 Feb 21; (60)Epub 2012 Feb 21.

Kobie JJ, Alcena DC, Zheng B, Bryk P, Mattiacio JL, Brewer M, Labranche C, Young FM, Dewhurst S, Montefiori DC, Rosenberg AF, Feng C, Jin X, Keefer MC, Sanz I. "9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity." PloS one.. 2012 7(4):e35356. Epub 2012 Apr 18.

Olsen JS, Easterhoff D, Dewhurst S. "Advances in HIV microbicide development." Future medicinal chemistry.. 2011 Dec; 3(16):2101-16.

Aggarwal S, Dewhurst S, Takimoto T, Kim B. "Biochemical impact of the host adaptation-associated PB2 E627K mutation on the temperature-dependent RNA synthesis kinetics of influenza A virus polymerase complex." The Journal of biological chemistry.. 2011 Oct 7; 286(40):34504-13. Epub 2011 Aug 04.

Hazard M, Steele S, Wang D, Pearson T, Scheideler M, Dewhurst S. "CTSA-IP: a solution to identifying and aggregating intellectual property across the NIH Clinical Translational Science Award (CTSA) consortium of biomedical research institutes." Clinical and translational science.. 2011 Oct; 4(5):328-31.

Domm W, Brooks L, Chung HL, Feng C, Bowers WJ, Watson G, McGrath JL, Dewhurst S. "Robust antigen-specific humoral immune responses to sublingually delivered adenoviral vectors encoding HIV-1 Env: association with mucoadhesion and efficient penetration of the sublingual barrier." Vaccine.. 2011 Sep 16; 29(40):7080-9. Epub 2011 Jul 27.

Bussey KA, Desmet EA, Mattiacio JL, Hamilton A, Bradel-Tretheway B, Bussey HE, Kim B, Dewhurst S, Takimoto T. "PA residues in the 2009 H1N1 pandemic influenza virus enhance avian influenza virus polymerase activity in mammalian cells." Journal of virology.. 2011 Jul; 85(14):7020-8. Epub 2011 May 11.

Caserta MT, Dewhurst S. "Dazed and confused by HHV-6." Blood.. 2011 May 12; 117(19):5016-8.

Mattiacio J, Walter S, Brewer M, Domm W, Friedman AE, Dewhurst S. "Dense display of HIV-1 envelope spikes on the lambda phage scaffold does not result in the generation of improved antibody responses to HIV-1 Env." Vaccine.. 2011 Mar 21; 29(14):2637-47. Epub 2011 Feb 18.

Easterhoff D, Dimaio JT, Doran TM, Dewhurst S, Nilsson BL. "Enhancement of HIV-1 infectivity by simple, self-assembling modular peptides." Biophysical journal.. 2011 Mar 2; 100(5):1325-34.

Polesskaya O, Silva J, Sanfilippo C, Desrosiers T, Sun A, Shen J, Feng C, Polesskiy A, Deane R, Zlokovic B, Kasischke K, Dewhurst S. "Methamphetamine causes sustained depression in cerebral blood flow." Brain research.. 2011 Feb 10; 1373:91-100. Epub 2010 Dec 13.

Lu SM, Tremblay MÈ, King IL, Qi J, Reynolds HM, Marker DF, Varrone JJ, Majewska AK, Dewhurst S, Gelbard HA. "HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells." PloS one.. 2011 6(9):e23915. Epub 2011 Sep 02.

Fong V, Osterbur M, Capella C, Kim YE, Hine C, Gorbunova V, Seluanov A, Dewhurst S. "Adenoviral vector driven by a minimal Rad51 promoter is selective for p53-deficient tumor cells." PloS one.. 2011 6(12):e28714. Epub 2011 Dec 09.

Polesskaya O, Cunningham LL, Francis SP, Luebke AE, Zhu X, Collins D, Vasilyeva ON, Sahler J, Desmet EA, Gelbard HA, Maggirwar SB, Walton JP, Frisina RD, Dewhurst S. "Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure." Hearing research.. 2010 Dec 1; 270(1-2):21-7. Epub 2010 Oct 27.

Olsen JS, Brown C, Capule CC, Rubinshtein M, Doran TM, Srivastava RK, Feng C, Nilsson BL, Yang J, Dewhurst S. "Amyloid-binding small molecules efficiently block SEVI (semen-derived enhancer of virus infection)- and semen-mediated enhancement of HIV-1 infection." The Journal of biological chemistry.. 2010 Nov 12; 285(46):35488-96. Epub 2010 Sep 10.

Gelbard HA, Dewhurst S, Maggirwar SB, Kiebala M, Polesskaya O, Gendelman HE. "Rebuilding synaptic architecture in HIV-1 associated neurocognitive disease: a therapeutic strategy based on modulation of mixed lineage kinase." Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics.. 2010 Oct; 7(4):392-8.

Gorantla S, Makarov E, Finke-Dwyer J, Gebhart CL, Domm W, Dewhurst S, Gendelman HE, Poluektova LY. "CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice." The Journal of immunology : official journal of the American Association of Immunologists.. 2010 Jun 15; 184(12):7082-91. Epub 2010 May 21.

Love TM, Thurston SW, Keefer MC, Dewhurst S, Lee HY. "Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequences." Journal of virology.. 2010 Jun; 84(11):5802-14. Epub 2010 Mar 24.

Desmet EA, Hollenbaugh JA, Sime PJ, Wright TW, Topham DJ, Sant AJ, Takimoto T, Dewhurst S, Maggirwar SB. "Mixed Lineage Kinase 3 deficiency delays viral clearance in the lung and is associated with diminished influenza-induced cytopathic effect in infected cells." Virology.. 2010 May 10; 400(2):224-32. Epub 2010 Feb 25.

Aggarwal S, Bradel-Tretheway B, Takimoto T, Dewhurst S, Kim B. "Biochemical characterization of enzyme fidelity of influenza A virus RNA polymerase complex." PloS one.. 2010 Apr 29; 5(4):e10372. Epub 2010 Apr 29.

Eggert D, Dash PK, Gorantla S, Dou H, Schifitto G, Maggirwar SB, Dewhurst S, Poluektova L, Gelbard HA, Gendelman HE. "Neuroprotective activities of CEP-1347 in models of neuroAIDS." The Journal of immunology : official journal of the American Association of Immunologists.. 2010 Jan 15; 184(2):746-56. Epub 2009 Dec 04.

Kennedy EM, Hergott C, Dewhurst S, Kim B. "The mechanistic architecture of thermostable Pyrococcus furiosus family B DNA polymerase motif A and its interaction with the dNTP substrate." Biochemistry.. 2009 Dec 1; 48(47):11161-8.

Bimber BN, Chugh P, Giorgi EE, Kim B, Almudevar AL, Dewhurst S, O'Connor DH, Lee HY. "Nef gene evolution from a single transmitted strain in acute SIV infection." Retrovirology.. 2009 Jun 8; 6:57. Epub 2009 Jun 08.

Schifitto G, Zhong J, Gill D, Peterson DR, Gaugh MD, Zhu T, Tivarus M, Cruttenden K, Maggirwar SB, Gendelman HE, Dewhurst S, Gelbard HA. "Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment." Journal of neurovirology.. 2009 Apr; 15(2):176-86.

Volcy K, Dewhurst S. "Proteasome inhibitors enhance bacteriophage lambda (lambda) mediated gene transfer in mammalian cells." Virology.. 2009 Feb 5; 384(1):77-87. Epub 2008 Dec 06.

Bradel-Tretheway BG, Kelley Z, Chakraborty-Sett S, Takimoto T, Kim B, Dewhurst S. "The human H5N1 influenza A virus polymerase complex is active in vitro over a broad range of temperatures, in contrast to the WSN complex, and this property can be attributed to the PB2 subunit." The Journal of general virology.. 2008 Dec; 89(Pt 12):2923-32.

Sapinoro R, Volcy K, Rodrigo WW, Schlesinger JJ, Dewhurst S. "Fc receptor-mediated, antibody-dependent enhancement of bacteriophage lambda-mediated gene transfer in mammalian cells." Virology.. 2008 Apr 10; 373(2):274-86. Epub 2008 Jan 14.

Chugh P, Bradel-Tretheway B, Monteiro-Filho CM, Planelles V, Maggirwar SB, Dewhurst S, Kim B. "Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy." Retrovirology.. 2008 Jan 31; 5:11. Epub 2008 Jan 31.

Taylor SR, Gonzalez-Begne M, Dewhurst S, Chimini G, Higgins CF, Melvin JE, Elliott JI. "Sequential shrinkage and swelling underlie P2X7-stimulated lymphocyte phosphatidylserine exposure and death." The Journal of immunology : official journal of the American Association of Immunologists.. 2008 Jan 1; 180(1):300-8.

Norman JP, Perry SW, Reynolds HM, Kiebala M, De Mesy Bentley KL, Trejo M, Volsky DJ, Maggirwar SB, Dewhurst S, Masliah E, Gelbard HA. "HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization." PloS one.. 2008 3(11):e3731. Epub 2008 Nov 14.

Sapinoro R, Maguire CA, Burgess A, Dewhurst S. "Enhanced transduction of dendritic cells by FcgammaRI-targeted adenovirus vectors." The journal of gene medicine.. 2007 Dec; 9(12):1033-45.

Duke CM, Maguire CA, Keefer MC, Federoff HJ, Bowers WJ, Dewhurst S. "HSV-1 amplicon vectors elicit polyfunctional T cell responses to HIV-1 Env, and strongly boost responses to an adenovirus prime." Vaccine.. 2007 Oct 16; 25(42):7410-21. Epub 2007 Aug 30.

Santos K, Sanfilippo CM, Narrow WC, Casey AE, Rodriguez-Colon SM, McDermott MP, Federoff HJ, Bowers WJ, Dewhurst S. "Infectivity of herpes simplex virus type-1 (HSV-1) amplicon vectors in dendritic cells is determined by the helper virus strain used for packaging." Journal of virological methods.. 2007 Oct; 145(1):37-46. Epub 2007 Jul 02.

Lankes HA, Zanghi CN, Santos K, Capella C, Duke CM, Dewhurst S. "In vivo gene delivery and expression by bacteriophage lambda vectors." Journal of applied microbiology.. 2007 May; 102(5):1337-49.

Malboeuf CM, Simon DA, Lee YE, Lankes HA, Dewhurst S, Frelinger JG, Rose RC. "Human papillomavirus-like particles mediate functional delivery of plasmid DNA to antigen presenting cells in vivo." Vaccine.. 2007 Apr 30; 25(17):3270-6. Epub 2007 Jan 22.

Sui Z, Sniderhan LF, Schifitto G, Phipps RP, Gelbard HA, Dewhurst S, Maggirwar SB. "Functional synergy between CD40 ligand and HIV-1 Tat contributes to inflammation: implications in HIV type 1 dementia." The Journal of immunology : official journal of the American Association of Immunologists.. 2007 Mar 1; 178(5):3226-36.

Gorantla S, Sneller H, Walters L, Sharp JG, Pirruccello SJ, West JT, Wood C, Dewhurst S, Gendelman HE, Poluektova L. "Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice." Journal of virology.. 2007 Mar; 81(6):2700-12. Epub 2006 Dec 20.

Dewhurst S, Maggirwar SB, Schifitto G, Gendelman HE, Gelbard HA. "Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS." Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.. 2007 Mar; 2(1):93-6. Epub 2006 Dec 16.

Santos K, Duke CM, Rodriguez-Colon SM, Dakwar A, Fan S, Keefer MC, Federoff HJ, Frelinger JG, Bowers WJ, Dewhurst S. "Effect of promoter strength on protein expression and immunogenicity of an HSV-1 amplicon vector encoding HIV-1 Gag." Vaccine.. 2007 Feb 19; 25(9):1634-46. Epub 2006 Nov 15.

Chugh P, Fan S, Planelles V, Maggirwar SB, Dewhurst S, Kim B. "Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line." Journal of molecular biology.. 2007 Feb 9; 366(1):67-81. Epub 2006 Nov 10.

Santos K, Simon DA, Conway E, Bowers WJ, Mitra S, Foster TH, Lugade A, Lord EM, Federoff HJ, Dewhurst S, Frelinger JG. "Spatial and temporal expression of herpes simplex virus type 1 amplicon-encoded genes: implications for their use as immunization vectors." Human gene therapy.. 2007 Feb; 18(2):93-105.

Gorantla, S., Sneller, H., Walters, L., Sharp, J.G., Pirruccello, S.J., West, J., Wood, C., Dewhurst, S., Gendelman, H.E., Poluektova, L. "A new paradigm for studies of HIV-1 pathobiology in humanized Balb/c-Rag2-/-?c-/- mice. J. Virol. PMCID: PMC1865995". 2007; : 81:2700-2712.

Zanghi CN, Sapinoro R, Bradel-Tretheway B, Dewhurst S. "A tractable method for simultaneous modifications to the head and tail of bacteriophage lambda and its application to enhancing phage-mediated gene delivery." Nucleic acids research.. 2007 35(8):e59. Epub 2007 Mar 28.

Sui Z, Fan S, Sniderhan L, Reisinger E, Litzburg A, Schifitto G, Gelbard HA, Dewhurst S, Maggirwar SB. "Inhibition of mixed lineage kinase 3 prevents HIV-1 Tat-mediated neurotoxicity and monocyte activation." The Journal of immunology : official journal of the American Association of Immunologists.. 2006 Jul 1; 177(1):702-11.

Santos K, Duke CM, Dewhurst S. "Amplicons as vaccine vectors." Current gene therapy.. 2006 Jun; 6(3):383-92.

Sui Z, Sniderhan LF, Fan S, Kazmierczak K, Reisinger E, Kovács AD, Potash MJ, Dewhurst S, Gelbard HA, Maggirwar SB. "Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons." The European journal of neuroscience.. 2006 May; 23(10):2623-34.

Hall CB, Caserta MT, Schnabel KC, McDermott MP, Lofthus GK, Carnahan JA, Gilbert LM, Dewhurst S. "Characteristics and acquisition of human herpesvirus (HHV) 7 infections in relation to infection with HHV-6." The Journal of infectious diseases.. 2006 Apr 15; 193(8):1063-9. Epub 2006 Mar 06.

Maguire CA, Sapinoro R, Girgis N, Rodriguez-Colon SM, Ramirez SH, Williams J, Dewhurst S. "Recombinant adenovirus type 5 vectors that target DC-SIGN, ChemR23 and alpha(v)beta3 integrin efficiently transduce human dendritic cells and enhance presentation of vectored antigens." Vaccine.. 2006 Jan 30; 24(5):671-82. Epub 2005 Aug 24.

Zeng L, Planelles V, Sui Z, Gartner S, Maggirwar SB, Dewhurst S, Ye L, Nerurkar VR, Yanagihara R, Lu Y. "HIV-1-based defective lentiviral vectors efficiently transduce human monocytes-derived macrophages and suppress replication of wild-type HIV-1." The journal of gene medicine.. 2006 Jan; 8(1):18-28.

Zanghi CN, Lankes HA, Bradel-Tretheway B, Wegman J, Dewhurst S. "A simple method for displaying recalcitrant proteins on the surface of bacteriophage lambda." Nucleic acids research.. 2005 Oct 13; 33(18):e160. Epub 2005 Oct 13.

Dou H, Ellison B, Bradley J, Kasiyanov A, Poluektova LY, Xiong H, Maggirwar S, Dewhurst S, Gelbard HA, Gendelman HE. "Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2005 Sep 14; 25(37):8375-85.

Zhen Z, Bradel-Tretheway B, Sumagin S, Bidlack JM, Dewhurst S. "The human herpesvirus 6 G protein-coupled receptor homolog U51 positively regulates virus replication and enhances cell-cell fusion in vitro." Journal of virology.. 2005 Sep; 79(18):11914-24.

Perry SW, Norman JP, Litzburg A, Zhang D, Dewhurst S, Gelbard HA. "HIV-1 transactivator of transcription protein induces mitochondrial hyperpolarization and synaptic stress leading to apoptosis." The Journal of immunology : official journal of the American Association of Immunologists.. 2005 Apr 1; 174(7):4333-44.

Fan S, Maguire CA, Ramirez SH, Bradel-Tretheway B, Sapinoro R, Sui Z, Chakraborty-Sett S, Dewhurst S. "Valproic acid enhances gene expression from viral gene transfer vectors." Journal of virological methods.. 2005 Apr; 125(1):23-33. Epub 2005 Jan 16.

Jin N, Kovács AD, Sui Z, Dewhurst S, Maggirwar SB. "Opposite effects of lithium and valproic acid on trophic factor deprivation-induced glycogen synthase kinase-3 activation, c-Jun expression and neuronal cell death." Neuropharmacology.. 2005 Mar; 48(4):576-83. Epub 2005 Jan 25.

Gorantla S, Santos K, Meyer V, Dewhurst S, Bowers WJ, Federoff HJ, Gendelman HE, Poluektova L. "Human dendritic cells transduced with herpes simplex virus amplicons encoding human immunodeficiency virus type 1 (HIV-1) gp120 elicit adaptive immune responses from human cells engrafted into NOD/SCID mice and confer partial protection against HIV-1 challenge." Journal of virology.. 2005 Feb; 79(4):2124-32.

Fan S, Ramirez SH, Garcia TM, Dewhurst S. "Dishevelled promotes neurite outgrowth in neuronal differentiating neuroblastoma 2A cells, via a DIX-domain dependent pathway." Brain research. Molecular brain research.. 2004 Dec 6; 132(1):38-50.

Diamond TL, Roshal M, Jamburuthugoda VK, Reynolds HM, Merriam AR, Lee KY, Balakrishnan M, Bambara RA, Planelles V, Dewhurst S, Kim B. "Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase." The Journal of biological chemistry.. 2004 Dec 3; 279(49):51545-53. Epub 2004 Sep 26.

Renda MJ, Bradel-Tretheway B, Planelles V, Bambara RA, Dewhurst S. "Inhibition of HIV type 1 replication using lentiviral-mediated delivery of mutant tRNA(Lys3)A58U." AIDS research and human retroviruses.. 2004 Dec; 20(12):1324-34.

Hall CB, Caserta MT, Schnabel KC, Boettrich C, McDermott MP, Lofthus GK, Carnahan JA, Dewhurst S. "Congenital infections with human herpesvirus 6 (HHV6) and human herpesvirus 7 (HHV7)." The Journal of pediatrics.. 2004 Oct; 145(4):472-7.

Caserta MT, McDermott MP, Dewhurst S, Schnabel K, Carnahan JA, Gilbert L, Lathan G, Lofthus GK, Hall CB. "Human herpesvirus 6 (HHV6) DNA persistence and reactivation in healthy children." The Journal of pediatrics.. 2004 Oct; 145(4):478-84.

Zhen Z, Bradel-Tretheway BG, Dewhurst S, Bidlack JM. "Transient overexpression of kappa and mu opioid receptors using recombinant adenovirus vectors." Journal of neuroscience methods.. 2004 Jul 30; 136(2):133-9.

Ramirez SH, Fan S, Maguire CA, Perry S, Hardiek K, Ramkumar V, Gelbard HA, Dewhurst S, Maggirwar SB. "Activation of adenosine A2A receptor protects sympathetic neurons against nerve growth factor withdrawal." Journal of neuroscience research.. 2004 Jul 15; 77(2):258-69.

Dewhurst S. "Human herpesvirus type 6 and human herpesvirus type 7 infections of the central nervous system." Herpes : the journal of the IHMF.. 2004 Jun; 11 Suppl 2:105A-111A.

Latchney LR, Fallon MA, Culp DJ, Gelbard HA, Dewhurst S. "Immunohistochemical assessment of fractalkine, inflammatory cells, and human herpesvirus 7 in human salivary glands." The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.. 2004 May; 52(5):671-81.

Lu Y, Liu C, Zeng L, Lin Z, Dewhurst S, Gartner S, Planelles V. "Efficient gene transfer into human monocyte-derived macrophages using defective lentiviral vectors." Cellular and molecular biology.. 2003 Nov; 49(7):1151-6.

Dou H, Birusingh K, Faraci J, Gorantla S, Poluektova LY, Maggirwar SB, Dewhurst S, Gelbard HA, Gendelman HE. "Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2003 Oct 8; 23(27):9162-70.

Diamond TL, Souroullas G, Weiss KK, Lee KY, Bambara RA, Dewhurst S, Kim B. "Mechanistic understanding of an altered fidelity simian immunodeficiency virus reverse transcriptase mutation, V148I, identified in a pig-tailed macaque." The Journal of biological chemistry.. 2003 Aug 8; 278(32):29913-24. Epub 2003 May 08.

Bradel-Tretheway BG, Zhen Z, Dewhurst S. "Effects of codon-optimization on protein expression by the human herpesvirus 6 and 7 U51 open reading frame." Journal of virological methods.. 2003 Aug; 111(2):145-56.

Wang X, Messerle M, Sapinoro R, Santos K, Hocknell PK, Jin X, Dewhurst S. "Murine cytomegalovirus abortively infects human dendritic cells, leading to expression and presentation of virally vectored genes." Journal of virology.. 2003 Jul; 77(13):7182-92.

Wang X, Wiley RD, Evans TG, Bowers WJ, Federoff HJ, Dewhurst S. "Cellular immune responses to helper-free HSV-1 amplicon particles encoding HIV-1 gp120 are enhanced by DNA priming." Vaccine.. 2003 Jun 2; 21(19-20):2288-97.

Richards JL, Abend JR, Miller ML, Chakraborty-Sett S, Dewhurst S, Whetter LE. "A peptide containing a novel FPGN CD40-binding sequence enhances adenoviral infection of murine and human dendritic cells." European journal of biochemistry. 2003 May; 270(10):2287-94.

Richards J, Miller M, Abend J, Koide A, Koide S, Dewhurst S. "Engineered fibronectin type III domain with a RGDWXE sequence binds with enhanced affinity and specificity to human alphavbeta3 integrin." Journal of molecular biology.. 2003 Mar 7; 326(5):1475-88.

Perry SW, Dewhurst S, Bellizzi MJ, Gelbard HA. "Tumor necrosis factor-alpha in normal and diseased brain: Conflicting effects via intraneuronal receptor crosstalk?" Journal of neurovirology.. 2002 Dec; 8(6):611-24.

Hocknell PK, Wiley RD, Wang X, Evans TG, Bowers WJ, Hanke T, Federoff HJ, Dewhurst S. "Expression of human immunodeficiency virus type 1 gp120 from herpes simplex virus type 1-derived amplicons results in potent, specific, and durable cellular and humoral immune responses." Journal of virology.. 2002 Jun; 76(11):5565-80.

Caserta MT, Mock DJ, Dewhurst S. "Human herpesvirus 6." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2001 Sep 15; 33(6):829-33. Epub 2001 Aug 10.

Ramirez SH, Sanchez JF, Dimitri CA, Gelbard HA, Dewhurst S, Maggirwar SB. "Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism." Journal of neurochemistry.. 2001 Aug; 78(4):874-89.

Tong N, Sanchez JF, Maggirwar SB, Ramirez SH, Guo H, Dewhurst S, Gelbard HA. "Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons." The European journal of neuroscience.. 2001 May; 13(10):1913-22.

Skrincosky D, Willis RA, Hocknell PK, Frelinger JG, Mirandola P, Wang X, Dewhurst S. "Epitope mapping of human herpesvirus-7 gp65 using monoclonal antibodies." Archives of virology.. 2001 146(9):1705-22.

Bal HP, Chroboczek J, Schoehn G, Ruigrok RW, Dewhurst S. "Adenovirus type 7 penton purification of soluble pentamers from Escherichia coli and development of an integrin-dependent gene delivery system." European journal of biochemistry. 2000 Oct; 267(19):6074-81.

Skrincosky D, Hocknell P, Whetter L, Secchiero P, Chandran B, Dewhurst S. "Identification and analysis of a novel heparin-binding glycoprotein encoded by human herpesvirus 7." Journal of virology.. 2000 May; 74(10):4530-40.

Tong N, Perry SW, Zhang Q, James HJ, Guo H, Brooks A, Bal H, Kinnear SA, Fine S, Epstein LG, Dairaghi D, Schall TJ, Gendelman HE, Dewhurst S, Sharer LR, Gelbard HA. "Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system." The Journal of immunology : official journal of the American Association of Immunologists.. 2000 Feb 1; 164(3):1333-9.

Maggirwar SB, Ramirez S, Tong N, Gelbard HA, Dewhurst S. "Functional interplay between nuclear factor-kappaB and c-Jun integrated by coactivator p300 determines the survival of nerve growth factor-dependent PC12 cells." Journal of neurochemistry.. 2000 Feb; 74(2):527-39.

Dewhurst SL, da Cruz RL, Whetter L. "Pathogenesis and treatment of HIV-1 infection: recent developments (Y2K update)." Frontiers in bioscience : a journal and virtual library.. 2000 Jan 1; 5:D30-49. Epub 2000 Jan 01.

Norton RA, Caserta MT, Hall CB, Schnabel K, Hocknell P, Dewhurst S. "Detection of human herpesvirus 6 by reverse transcription-PCR." Journal of clinical microbiology.. 1999 Nov; 37(11):3672-5.

Dominguez G, Dambaugh TR, Stamey FR, Dewhurst S, Inoue N, Pellett PE. "Human herpesvirus 6B genome sequence: coding content and comparison with human herpesvirus 6A." Journal of virology.. 1999 Oct; 73(10):8040-52.

Hodge S, de Rosayro J, Glenn A, Ojukwu IC, Dewhurst S, McClure HM, Bischofberger N, Anderson DC, Klumpp SA, Novembre FJ. "Postinoculation PMPA treatment, but not preinoculation immunomodulatory therapy, protects against development of acute disease induced by the unique simian immunodeficiency virus SIVsmmPBj." Journal of virology.. 1999 Oct; 73(10):8630-9.

Maggirwar SB, Tong N, Ramirez S, Gelbard HA, Dewhurst S. "HIV-1 Tat-mediated activation of glycogen synthase kinase-3beta contributes to Tat-mediated neurotoxicity." Journal of neurochemistry.. 1999 Aug; 73(2):578-86.

Wilhelm K, Parker G, Dewhurst-Savellis J, Asghari A. "Psychological predictors of single and recurrent major depressive episodes." Journal of affective disorders.. 1999 Jul; 54(1-2):139-47.

Whetter LE, Ojukwu IC, Novembre FJ, Dewhurst S. "Pathogenesis of simian immunodeficiency virus infection." The Journal of general virology.. 1999 Jul; 80 ( Pt 7):1557-68.

Fine SM, Maggirwar SB, Elliott PR, Epstein LG, Gelbard HA, Dewhurst S. "Proteasome blockers inhibit TNF-alpha release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia." Journal of neuroimmunology.. 1999 Mar 1; 95(1-2):55-64.

Hodge S, Novembre FJ, Whetter L, Gelbard HA, Dewhurst S. "Induction of fas ligand expression by an acutely lethal simian immunodeficiency virus, SIVsmmPBj14." Virology.. 1998 Dec 20; 252(2):354-63.

Maggirwar SB, Sarmiere PD, Dewhurst S, Freeman RS. "Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1998 Dec 15; 18(24):10356-65.

Rotola A, Ravaioli T, Gonelli A, Dewhurst S, Cassai E, Di Luca D. "U94 of human herpesvirus 6 is expressed in latently infected peripheral blood mononuclear cells and blocks viral gene expression in transformed lymphocytes in culture." Proceedings of the National Academy of Sciences of the United States of America.. 1998 Nov 10; 95(23):13911-6.

Deng SX, Panahian N, James H, Gelbard HA, Federoff HJ, Dewhurst S, Epstein LG. "Luciferase: a sensitive and quantitative probe for blood-brain barrier disruption." Journal of neuroscience methods.. 1998 Sep 1; 83(2):159-64.

Hodge S, Novembre FJ, Dewhurst S. "Endogenous tumor necrosis factor-alpha contributes to lymphoproliferation induced by simian immunodeficiency virus variant, SIVsmmPBj14." Immunology letters.. 1998 Aug; 63(1):49-51.

Perry SW, Hamilton JA, Tjoelker LW, Dbaibo G, Dzenko KA, Epstein LG, Hannun Y, Whittaker JS, Dewhurst S, Gelbard HA. "Platelet-activating factor receptor activation. An initiator step in HIV-1 neuropathogenesis." The Journal of biological chemistry.. 1998 Jul 10; 273(28):17660-4.

New DR, Maggirwar SB, Epstein LG, Dewhurst S, Gelbard HA. "HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism." The Journal of biological chemistry.. 1998 Jul 10; 273(28):17852-8.

Whetter L, Novembre FJ, Saucier M, Gummuluru S, Dewhurst S. "Costimulatory pathways in lymphocyte proliferation induced by the simian immunodeficiency virus SIVsmmPBj14." Journal of virology.. 1998 Jul; 72(7):6155-8.

Saucier M, Hodge S, Dewhurst S, Gibson T, Gibson JP, McClure HM, Novembre FJ. "The tyrosine-17 residue of Nef in SIVsmmPBj14 is required for acute pathogenesis and contributes to replication in macrophages." Virology.. 1998 May 10; 244(2):261-72.

Deng H, Dewhurst S. "Functional identification and analysis of cis-acting sequences which mediate genome cleavage and packaging in human herpesvirus 6." Journal of virology.. 1998 Jan; 72(1):320-9.

Hall CB, Caserta MT, Schnabel KC, Long C, Epstein LG, Insel RA, Dewhurst S. "Persistence of human herpesvirus 6 according to site and variant: possible greater neurotropism of variant A." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 1998 Jan; 26(1):132-7.

Bulboaca GH, Deng H, Dewhurst S, Calos MP. "Telomeric sequences from human herpesvirus 6 do not mediate nuclear retention of episomal DNA in human cells." Archives of virology.. 1998 143(3):563-70.

Bar-Peled O, Ben-Hur H, Biegon A, Groner Y, Dewhurst S, Furuta A, Rothstein JD. "Distribution of glutamate transporter subtypes during human brain development." Journal of neurochemistry.. 1997 Dec; 69(6):2571-80.

Dewhurst S, Skrincosky D, van Loon N. "Human herpesvirus 7." Expert reviews in molecular medicine. 1997 Nov 18; 1997:1-10. Epub 1997 Nov 18.

Dewhurst S, Skrincosky D, van Loon N. "Human herpesvirus 6." Expert reviews in molecular medicine. 1997 Nov 5; 1997:1-17. Epub 1997 Nov 05.

Walker P, Hitch GJ, Dewhurst SA, Whiteley HE, Brandimonte MA. "The representation of nonstructural information in visual memory: evidence from image combination." Memory & cognition.. 1997 Jul; 25(4):484-91.

Krajewski S, James HJ, Ross J, Blumberg BM, Epstein LG, Gendelman HE, Gummuluru S, Dewhurst S, Sharer LR, Reed JC, Gelbard HA. "Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis." Neuropathology and applied neurobiology.. 1997 Jun; 23(3):242-53.

Dykes C, Chan H, Krenitsky DM, Dewhurst S. "Stringent structural and sequence requirements of the human herpesvirus 6B lytic-phase origin of DNA replication." The Journal of general virology.. 1997 May; 78 ( Pt 5):1125-9.

van Loon N, Dykes C, Deng H, Dominguez G, Nicholas J, Dewhurst S. "Identification and analysis of a lytic-phase origin of DNA replication in human herpesvirus 7." Journal of virology.. 1997 Apr; 71(4):3279-84.

Dewhurst S, Whetter L. "Pathogenesis and treatment of HIV-1 infection: recent developments." Frontiers in bioscience : a journal and virtual library.. 1997 Mar 1; 2:d147-59. Epub 1997 Mar 01.

Gummuluru S, Novembre FJ, Lewis M, Gelbard HA, Dewhurst S. "Apoptosis correlates with immune activation in intestinal lymphoid tissue from macaques acutely infected by a highly enteropathic simian immunodeficiency virus, SIVsmmPBj14." Virology.. 1996 Nov 1; 225(1):21-32.

Fine SM, Angel RA, Perry SW, Epstein LG, Rothstein JD, Dewhurst S, Gelbard HA. "Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia." The Journal of biological chemistry.. 1996 Jun 28; 271(26):15303-6.

Dewhurst S, Sander DM, Sgro JY. "Resources for HIV/AIDS on the Internet." Molecular medicine today. 1996 Feb; 2(2):52-7.

Gummuluru S, Novembre FJ, Seshi B, Dewhurst S. "SIVsmmPBj14 induces expression of a mucosal integrin on macaque lymphocytes." Virology.. 1996 Jan 1; 215(1):97-100.

Dewhurst S, Gelbard HA, Fine SM. "Neuropathogenesis of AIDS." Molecular medicine today. 1996 Jan; 2(1):16-23.

Secchiero P, Nicholas J, Deng H, Xiaopeng T, van Loon N, Ruvolo VR, Berneman ZN, Reitz MS, Dewhurst S. "Identification of human telomeric repeat motifs at the genome termini of human herpesvirus 7: structural analysis and heterogeneity." Journal of virology.. 1995 Dec; 69(12):8041-5.

Dollard SC, James HJ, Sharer LR, Epstein LG, Gelbard HA, Dewhurst S. "Activation of nuclear factor kappa B in brains from children with HIV-1 encephalitis." Neuropathology and applied neurobiology.. 1995 Dec; 21(6):518-28.

van Loon NM, Gummuluru S, Sherwood DJ, Marentes R, Hall CB, Dewhurst S. "Direct sequence analysis of human herpesvirus 6 (HHV-6) sequences from infants and comparison of HHV-6 sequences from mother/infant pairs." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 1995 Oct; 21(4):1017-9.

Frenkel LM, Wagner LE, Demeter LM, Dewhurst S, Coombs RW, Murante BL, Reichman RC. "Effects of zidovudine use during pregnancy on resistance and vertical transmission of human immunodeficiency virus type 1." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 1995 May; 20(5):1321-6.

Talley AK, Dewhurst S, Perry SW, Dollard SC, Gummuluru S, Fine SM, New D, Epstein LG, Gendelman HE, Gelbard HA. "Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA." Molecular and cellular biology.. 1995 May; 15(5):2359-66.

Saito Y, Sharer LR, Dewhurst S, Blumberg BM, Hall CB, Epstein LG. "Cellular localization of human herpesvirus-6 in the brains of children with AIDS encephalopathy." Journal of neurovirology.. 1995 Mar; 1(1):30-9.

Frenkel LM, Wagner LE, Atwood SM, Cummins TJ, Dewhurst S. "Specific, sensitive, and rapid assay for human immunodeficiency virus type 1 pol mutations associated with resistance to zidovudine and didanosine." Journal of clinical microbiology.. 1995 Feb; 33(2):342-7.

Dollard SC, Gummuluru S, Tsang S, Fultz PN, Dewhurst S. "Enhanced responsiveness to nuclear factor kappa B contributes to the unique phenotype of simian immunodeficiency virus variant SIVsmmPBj14." Journal of virology.. 1994 Dec; 68(12):7800-9.

Caserta MT, Hall CB, Schnabel K, McIntyre K, Long C, Costanzo M, Dewhurst S, Insel R, Epstein LG. "Neuroinvasion and persistence of human herpesvirus 6 in children." The Journal of infectious diseases.. 1994 Dec; 170(6):1586-9.

Dewhurst S, Krenitsky DM, Dykes C. "Human herpesvirus 6B origin: sequence diversity, requirement for two binding sites for origin-binding protein, and enhanced replication from origin multimers." Journal of virology.. 1994 Oct; 68(10):6799-803.

Hall CB, Long CE, Schnabel KC, Caserta MT, McIntyre KM, Costanzo MA, Knott A, Dewhurst S, Insel RA, Epstein LG. "Human herpesvirus-6 infection in children. A prospective study of complications and reactivation." The New England journal of medicine.. 1994 Aug 18; 331(7):432-8.

Thomson BJ, Dewhurst S, Gray D. "Structure and heterogeneity of the a sequences of human herpesvirus 6 strain variants U1102 and Z29 and identification of human telomeric repeat sequences at the genomic termini." Journal of virology.. 1994 May; 68(5):3007-14.

Dewhurst S, Dollard SC, Pellett PE, Dambaugh TR. "Identification of a lytic-phase origin of DNA replication in human herpesvirus 6B strain Z29." Journal of virology.. 1993 Dec; 67(12):7680-3.

Krohn KJ, Hakkarainen K, Aavik E, Dewhurst S, Sadaie R, Mullins JI. "Transcomplementation of simian immunodeficiency virus Rev with human T-cell leukemia virus type I Rex." Journal of virology.. 1993 Sep; 67(9):5681-4.

Dewhurst S, McIntyre K, Schnabel K, Hall CB. "Human herpesvirus 6 (HHV-6) variant B accounts for the majority of symptomatic primary HHV-6 infections in a population of U.S. infants." Journal of clinical microbiology.. 1993 Feb; 31(2):416-8.

Dewhurst S, Chandran B, McIntyre K, Schnabel K, Hall CB. "Phenotypic and genetic polymorphisms among human herpesvirus-6 isolates from North American infants." Virology.. 1992 Sep; 190(1):490-3.

Dewhurst S, Embretson JE, Fultz PN, Mullins JI. "Molecular clones from a non-acutely pathogenic derivative of SIVsmmPBj14: characterization and comparison to acutely pathogenic clones." AIDS research and human retroviruses.. 1992 Jun; 8(6):1179-87.

Iglewski WJ, Dewhurst S. "Cellular mono(ADP-ribosyl) transferase inhibits protein synthesis." FEBS letters.. 1991 Jun 3; 283(2):235-8.

Dewhurst S, Embretson JE, Anderson DC, Mullins JI, Fultz PN. "Sequence analysis and acute pathogenicity of molecularly cloned SIVSMM-PBj14." Nature.. 1990 Jun 14; 345(6276):636-40.

Smith DB, Mosely RP, Begent RH, Coakham HB, Glaser MG, Dewhurst S, Kelly A, Bagshawe KD. "Quantitative distribution of 131I-labelled monoclonal antibodies administered by the intra-ventricular route." European journal of cancer : official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR).. 1990 Feb; 26(2):129-36.

Fultz PN, Anderson DC, McClure HM, Dewhurst S, Mullins JI. "SIVsmm infection of macaque and mangabey monkeys: correlation between in vivo and in vitro properties of different isolates." Developments in biological standardization. 1990 72:253-8.

Mullins JI, Hoover EA, Donahue PR, Dewhurst S, Quackenbush SL, Murphey-Corb M, Martin LN, Fultz PN, Gallo MV, Reinhart TA. "The FeLV and SIV AIDS pathogenesis models: search for and analysis of molecularly defined pathogens." Developments in biological standardization. 1990 72:167-71.

Green AJ, Dewhurst SE, Begent RH, Bagshawe KD, Riggs SJ. "Accurate quantification of 131I distribution by gamma camera imaging." European journal of nuclear medicine.. 1990 16(4-6):361-5.

Sakai K, Dewhurst S, Ma XY, Volsky DJ. "Differences in cytopathogenicity and host cell range among infectious molecular clones of human immunodeficiency virus type 1 simultaneously isolated from an individual." Journal of virology.. 1988 Nov; 62(11):4078-85.

Dewhurst S, Sakai K, Zhang XH, Wasiak A, Volsky DJ. "Establishment of human glial cell lines chronically infected with the human immunodeficiency virus." Virology.. 1988 Jan; 162(1):151-9.

Dewhurst S, Sakai K, Bresser J, Stevenson M, Evinger-Hodges MJ, Volsky DJ. "Persistent productive infection of human glial cells by human immunodeficiency virus (HIV) and by infectious molecular clones of HIV." Journal of virology.. 1987 Dec; 61(12):3774-82.

Dewhurst S, Stevenson M, Volsky DJ. "Expression of the T4 molecule (AIDS virus receptor) by human brain-derived cells." FEBS letters.. 1987 Mar 9; 213(1):133-7.

Dewhurst S, Bresser J, Stevenson M, Sakai K, Evinger-Hodges MJ, Volsky DJ. "Susceptibility of human glial cells to infection with human immunodeficiency virus (HIV)." FEBS letters.. 1987 Mar 9; 213(1):138-43.

Dewhurst S, Stevenson M, McComb RD, Volsky DJ. "Expression of glial fibrillary acidic protein in human glioma cell lines as detected by molecular hybridization." Acta neuropathologica.. 1987 73(4):383-6.

Smith DM, Dewhurst S, Shepherd S, Volsky DJ, Goldsmith JC. "False-positive enzyme-linked immunosorbent assay reactions for antibody to human immunodeficiency virus in a population of midwestern patients with congenital bleeding disorders." Transfusion.. 1987 27(1):112.

Volsky DJ, Sakai K, Stevenson M, Dewhurst S. "Retroviral etiology of the acquired immune deficiency syndrome (AIDS)." AIDS research. 1986 Dec; 2 Suppl 1:S35-48.

Goldsmith JC, Dewhurst S, Hedenskog M, Casareale D, Volsky DJ. "High prevalence and high titers of LAV/HTLV-III antibodies in healthy hemophiliacs in the midwestern United States." The American journal of medicine.. 1986 Oct; 81(4):579-83.

Hedenskog M, Dewhurst S, Ludvigsen C, Sinangil F, Rodriguez L, Wu YT, Volsky DJ. "Testing for antibodies to AIDS-associated retrovirus (HTLV-III/LAV) by indirect fixed cell immunofluorescence: specificity, sensitivity, and applications." Journal of medical virology.. 1986 Aug; 19(4):325-34.

Dewhurst S, Volsky DJ. "A simple method for the production of specific antiserum to the second nuclear antigen (EBNA-2) of Epstein-Barr virus (EBV)." Journal of immunological methods.. 1986 Mar 13; 87(2):283-7.

Volsky DJ, Wu YT, Stevenson M, Dewhurst S, Sinangil F, Merino F, Rodriguez L, Godoy G. "Antibodies to HTLV-III/LAV in Venezuelan patients with acute malarial infections." The New England journal of medicine.. 1986 Mar 6; 314(10):647-8.

Volsky DJ, Rodriguez L, Dewhurst S, Sinangil F, Sakai K, Merino F, Esparza B, De Salvo L. "Antibodies to acquired immune deficiency syndrome (AIDS)-associated virus (HTLV-III/LAV) in Venezuelan populations." AIDS research. 1986 2(2):79-92.

Rodriquez L, Dewhurst S, Sinangil F, Merino F, Godoy G, Volsky DJ. "Antibodies to HTLV-III/LAV among aboriginal Amazonian Indians in Venezuela." Lancet.. 1985 Nov 16; 2(8464):1098-100.

Casareale D, Dewhurst S, Sonnabend J, Sinangil F, Purtilo DT, Volsky DJ. "Prevalence of AIDS-associated retrovirus and antibodies among male homosexuals at risk for AIDS in Greenwich Village." AIDS research. 1984 1(6):407-21.