Research Bio
As an environmental epidemiologist, Dr. Jusko's research interests concern the environmental causes of human disease. Within this broad area, Dr. Jusko's research primarily focuses on how environmental chemicals contribute to adverse immunological development over the entire lifespan. He is interested in the immune system as both a disease outcome (e.g., asthma, lowered vaccine response, development of autoimmunity), and as a mechanism of susceptibility for other disease outcomes, such as neurobehavioral development.
Dr. Jusko is exploring these questions in a diverse set of populations. For instance, he is investigating whether in utero and early postnatal exposure to persistent pollutants is associated with measures of immune system function in a cohort of children in eastern Slovakia. In adults, he is examining whether chemical exposures are associated with antinuclear antibodies (ANA), autoantibodies frequently observed in individuals with systemic autoimmune diseases such as systemic lupus erythematosus (SLE). He is also a longtime collaborator on the Rochester Lead Study, which examines the potential neurobehavioral effects of early life lead exposure in a cohort of children in Rochester NY, and an NIEHS-led project examining neurodevelopment in a birth cohort of approximately 10,000 mother-infant pairs (the Generation R Study) in relation to in utero exposure to organophosphate pesticide metabolites.
2016 Oct
Koštiaková V, Moleti A, Wimmerová S, Jusko TA, Palkovi?ová Murínová ?, Sisto R, Richterová D, Ková? J, ?onka K, Patayová H, Tihányi J, Trnovec T. "DPOAEs in infants developmentally exposed to PCBs show two differently time spaced exposure sensitive windows." Chemosphere. 2016 Oct; 161:518-26. Epub 2016 Jul 26. |
2016 Aug 30
Wimmerová S, van den Berg M, Chovancová J, Patayová H, Jusko TA, van Duursen MB, Palkovi?ová Murínová ?, Canton RF, van Ede KI, Trnovec T. "Relative effect potency estimates of dioxin-like activity for dioxins, furans, and dioxin-like PCBs in adults based on cytochrome P450 1A1 and 1B1 gene expression in blood." Environment international. 2016 Aug 30; 96:24-33. Epub 2016 Aug 30. |
2016 Aug 20
Palkovi?ová Murínová ?, Moleti A, Sisto R, Wimmerová S, Jusko TA, Tihányi J, Jure?ková D, Ková? J, Koštiaková V, Drobná B, Trnovec T. "PCB exposure and cochlear function at age 6 years." Environmental research. 2016 Aug 20; 151:428-435. Epub 2016 Aug 20. |
2016 Jul 5
Jusko T, Oktapodas M, Palkovi?ová Murinová ?, Babinska K, Babjakova J, Verner MA, DeWitt J, Thevenet-Morrison K, Conka K, Drobná B, Chovancova J, Thurston S, Lawrence BP, Dozier A, Jarvinen K, Patayova H, Trnovec T, Legler J, Hertz-Picciotto I, Lamoree MH. "Demographic, Reproductive, and Dietary Determinants of Perfluorooctane Sulfonic (PFOS) and Perfluorooctanoic Acid (PFOA) Concentrations in Human Colostrum." Environmental science & technology. 2016 Jul 5; 50(13):7152-62. Epub 2016 Jun 14. |
2016 Jun
Jusko TA, De Roos AJ, Lee SY, Thevenet-Morrison K, Schwartz SM, Verner MA, Palkovicova Murinova L, Drobná B, Ko?an A, Fabišiková A, ?onka K, Trnovec T, Hertz-Picciotto I, Lawrence BP. "A Birth Cohort Study of Maternal and Infant Serum PCB-153 and DDE Concentrations and Responses to Infant Tuberculosis Vaccination." Environmental health perspectives. 2016 Jun; 124(6):813-21. Epub 2015 Dec 09. |
