Helene McMurray, Ph.D.

(Pronouns: she/her/hers)

Contact Information

Phone Numbers

Office: (585) 276-4368

Research Labs

Clinical Interests

Visit Clinical Interests Lab Website

Research Projects

Visit Research Projects Lab Website

Locations

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 626
Rochester, NY 14642

Faculty Appointments

Associate Professor - Department of Pathology and Laboratory Medicine (SMD)

Biography

Professional Background

Dr. Helene R. McMurray, Ph.D., is currently Director-in-Training in the Tissue Typing / Histocompatibility Laboratory, which provides state-of-the-art compatibility testing for the solid organ and stem cell transplantation services including HLA typing by molecular methods, antibody screening and identification, and cross-matching.

Research

Dr. McMurray conducts collaborative research projects using approaches in genomics, bioinformatics, biostatistics, genetics and cell and molecular biology. With Dr. Hartmut "Hucky" Land, she examines molecular mechanisms underlying malignant cell transformation to find cancer cell vulnerabilities. To identify pharmacologic means of targeting such vulnerabilities, Dr. McMurray collaborates with Dr. Mark Noble. She also regularly contributes her bioinformatics and genomics expertise to projects with colleagues in biostatistics, neuroscience, and most recently, dermatology.

Credentials

Education

1998
BS | Cornell University
Biological Science

2003
PhD | University of Rochester School of Medicine & Dentistry
Microbiology

Post-doctoral Training & Residency

2003 - 2009
Postdoctoral Fellow, Laboratory of Dr. Hartmut Land, Department of Biomedical Genetics, University of Rochester, School of Medicine and Dentistry, Rochester, NY

Awards

2014
The Graduate Student Society Faculty Award
Sponsor: Graduate Student Society
Location: University of Rochester School of Medicine and Dentistry

2008
Wilson A. Stone Memorial Award
Location: University of Texas, M. D. Anderson Cancer Center, Houston, TX

2008
Outstanding Poster by a Post-Doctoral Fellow, University Day in Genetics
Sponsor: University of Rochester Post-Doctoral Association
Location: University of Rochester, Rochester, NY

2003 - 2006
Postdoctoral Fellowship
Sponsor: National Institutes of Health
Location: James P. Wilmot Cancer Center, University of Rochester, School o

2002
GSS Merit Award
Sponsor: Graduate Student Society
Location: University of Rochester, Rochester, NY

2001 - 2003
Pre-Doctoral Fellowship
Sponsor: National Institutes of Health
Location: Center for Oral Biology, University of Rochester, School of Medi

1996 - 1997
Cornell Tradition Summer Research Fellowship
Location: Cornell University, Ithaca, NY

1994 - 1998
Cornell Tradition Fellowship
Location: Cornell University, Ithaca, NY

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Publications

Journal Articles

9/30/2022
McMurray HR, Stern HA, Ambeskovic A, Land H, McCall MN. "Protocol to use TopNet for gene regulatory network modeling using gene expression data from perturbation experiments." STAR protocols.. 2022 Sep 30; 3(4):101737. Epub 2022 Sep 30.

12/21/2021
McMurray HR, Ambeskovic A, Newman LA, Aldersley J, Balakrishnan V, Smith B, Stern HA, Land H, McCall MN. "Gene network modeling via TopNet reveals functional dependencies between diverse tumor-critical mediator genes." Cell reports.. 2021 Dec 21; 37(12):110136.

11/26/2020
Sherina V, McMurray HR, Powers W, Land H, Love TMT, McCall MN. "Multiple imputation and direct estimation for qPCR data with non-detects." BMC bioinformatics.. 2020 Nov 26; 21(1):545. Epub 2020 Nov 26.

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