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Brian J. Altman, Ph.D.


Showing all 23 journal articles & 2 books available

Journal Articles

Pariollaud M, Ibrahim LH, Irizarry E, Mello RM, Chan AB, Altman BJ, Shaw RJ, Bollong MJ, Wiseman RL, Lamia KA. "Circadian disruption enhances HSF1 signaling and tumorigenesis in -driven lung cancer." Science advances.. 2022 Sep 30; 8(39):eabo1123. Epub 2022 Sep 28.

Yee M, McDavid AN, Cohen ED, Huyck HL, Poole C, Altman BJ, Maniscalco WM, Deutsch GH, Pryhuber GS, O'Reilly MA. "Neonatal Hyperoxia Activates ATF4 to Stimulate Folate Metabolism and AT2 Cell Proliferation." American journal of respiratory cell and molecular biology.. 2022 Jan 19; Epub 2022 Jan 19.

Kleckner AS, Altman BJ, Reschke JE, Kleckner IR, Culakova E, Dunne RF, Mustian KM, Peppone LJ. "Time-restricted Eating to Address Cancer-related Fatigue among Cancer Survivors: A Single-arm Pilot Study." Journal of integrative oncology.. 2022 11(4)Epub 2022 May 30.

Burchett JB, Knudsen-Clark AM, Altman BJ. "MYC Ran Up the Clock: The Complex Interplay between MYC and the Molecular Circadian Clock in Cancer." International journal of molecular sciences.. 2021 Jul 20; 22(14)Epub 2021 Jul 20.

Bu Y, Yoshida A, Chitnis N, Altman BJ, Tameire F, Oran A, Gennaro V, Armeson KE, McMahon SB, Wertheim GB, Dang CV, Ruggero D, Koumenis C, Fuchs SY, Diehl JA. "A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival." Nature cell biology.. 2018 Jan; 20(1):104-115. Epub 2017 Dec 11.

Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM. "Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism." Cell metabolism.. 2017 Apr 4; 25(4):961-974.e4.

Altman BJ, Hsieh AL, Gouw AM, Dang CV. "Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERB?." Nature communications.. 2017 Mar 23; 8:14862. Epub 2017 Mar 23.

Altman BJ, Stine ZE, Dang CV. "From Krebs to clinic: glutamine metabolism to cancer therapy." Nature reviews. Cancer.. 2016 Oct; 16(10):619-34. Epub 2016 Jul 29.

Altman BJ. "Cancer Clocks Out for Lunch: Disruption of Circadian Rhythm and Metabolic Oscillation in Cancer." Frontiers in cell and developmental biology.. 2016 4:62. Epub 2016 Jun 24.

Altman BJ, Hsieh AL, Sengupta A, Krishnanaiah SY, Stine ZE, Walton ZE, Gouw AM, Venkataraman A, Li B, Goraksha-Hicks P, Diskin SJ, Bellovin DI, Simon MC, Rathmell JC, Lazar MA, Maris JM, Felsher DW, Hogenesch JB, Weljie AM, Dang CV. "MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells." Cell metabolism.. 2015 Dec 1; 22(6):1009-19. Epub 2015 Sep 17.

Stine ZE, Walton ZE, Altman BJ, Hsieh AL, Dang CV. "MYC, Metabolism, and Cancer." Cancer discovery.. 2015 Oct; 5(10):1024-39. Epub 2015 Sep 17.

Hsieh AL, Walton ZE, Altman BJ, Stine ZE, Dang CV. "MYC and metabolism on the path to cancer." Seminars in cell & developmental biology.. 2015 Jul; 43:11-21. Epub 2015 Aug 12.

Xiang Y, Stine ZE, Xia J, Lu Y, O'Connor RS, Altman BJ, Hsieh AL, Gouw AM, Thomas AG, Gao P, Sun L, Song L, Yan B, Slusher BS, Zhuo J, Ooi LL, Lee CG, Mancuso A, McCallion AS, Le A, Milone MC, Rayport S, Felsher DW, Dang CV. "Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis." The Journal of clinical investigation.. 2015 Jun; 125(6):2293-306. Epub 2015 Apr 27.

Altman BJ, Rathmell JC. "Metabolic stress in autophagy and cell death pathways." Cold Spring Harbor perspectives in biology.. 2012 Sep 1; 4(9):a008763. Epub 2012 Sep 01.

Altman BJ, Dang CV. "Normal and cancer cell metabolism: lymphocytes and lymphoma." The FEBS journal.. 2012 Aug; 279(15):2598-609. Epub 2012 Jul 03.

Wang X, Eno CO, Altman BJ, Zhu Y, Zhao G, Olberding KE, Rathmell JC, Li C. "ER stress modulates cellular metabolism." The Biochemical journal.. 2011 Apr 1; 435(1):285-96.

Coloff JL, Mason EF, Altman BJ, Gerriets VA, Liu T, Nichols AN, Zhao Y, Wofford JA, Jacobs SR, Ilkayeva O, Garrison SP, Zambetti GP, Rathmell JC. "Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells." The Journal of biological chemistry.. 2011 Feb 18; 286(7):5921-33. Epub 2010 Dec 15.

Altman BJ, Rathmell JC. "Autophagy: not good OR bad, but good AND bad." Autophagy.. 2009 May; 5(4):569-70.

Wieman HL, Horn SR, Jacobs SR, Altman BJ, Kornbluth S, Rathmell JC. "An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking." The Biochemical journal.. 2009 Mar 1; 418(2):345-67.

Altman BJ, Wofford JA, Zhao Y, Coloff JL, Ferguson EC, Wieman HL, Day AE, Ilkayeva O, Rathmell JC. "Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis." Molecular biology of the cell.. 2009 Feb; 20(4):1180-91. Epub 2008 Dec 24.

Zhao Y, Altman BJ, Coloff JL, Herman CE, Jacobs SR, Wieman HL, Wofford JA, Dimascio LN, Ilkayeva O, Kelekar A, Reya T, Rathmell JC. "Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1." Molecular and cellular biology.. 2007 Jun; 27(12):4328-39. Epub 2007 Mar 19.

Lue NF, Bosoy D, Moriarty TJ, Autexier C, Altman B, Leng S. "Telomerase can act as a template- and RNA-independent terminal transferase." Proceedings of the National Academy of Sciences of the United States of America.. 2005 Jul 12; 102(28):9778-83. Epub 2005 Jun 30.

Macfarlan T, Kutney S, Altman B, Montross R, Yu J, Chakravarti D. "Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor." The Journal of biological chemistry.. 2005 Feb 25; 280(8):7346-58. Epub 2004 Nov 23.

Books & Chapters

Chapter Title: Circadian Clock's Cancer Connections
Book Title: Annual Review of Cancer Biology
Author List: Walton ZE, Altman BJ, Brooks RC, and Dang CV
Published By: Annual Reviews2018

Chapter Title: Deregulation of the cellular energetics of cancer cells
Book Title: Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanism
Author List: Stine ZE, Altman BJ, Hsieh AL, Gouw AM, and Dang CV
Published By: Elsevier2014