Jeffery Michael Purkerson, Ph.D.

Jeffery Michael Purkerson, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 777
Rochester, NY 14642

Office: (585) 273-3974

Journal Articles

Showing all 21 journal articles available.

Chambrey, R.; Kurth. I.;Peti-Peterdi J.;Houillier, P.;Purkerson, J.;Leviel,F.;Zbedik, A.;Schwartz,G.J.;Huebner,C.;Eladari, D. "Renal Intercalated cells are rather energized by a proton than a sodium-pump." PNAS. 2013; .
Purkerson JM; Tsuruoka S; Suter DZ; Nakamori A; Schwartz GJ. "Adaptation to metabolic acidosis and its recovery are associated with changes in anion exchanger distribution and expression in the cortical collecting duct". Kindney International. 2010; 78(10): 993-1005.
2009 Dec
Peng H, Vijayakumar S, Schiene-Fischer C, Li H, Purkerson JM, Malesevic M, Liebscher J, Al-Awqati, Schwartz GJ. "Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation." Journal of Biological Chemistry. 2009; 284(10): 6465-75.
Peng H; Vijayakumar S; Schiene-Fischer C; Li H; Purkerson JM; Malesevic M; Liebscher J; Al-Awqati Q; Schwartz GJ. "Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation." Journal of Biological Chemistry. 2008; 284(10): 6465-75.
2007 Mar
Purkerson JM, Kittelberger AM, Schwartz GJ. "Basolateral carbonic anhydrase IV in the proximal tubule is a glycosylphosphatidylinositol-anchored protein." Kidney international. 2007 Mar; 71(5):407-16. Epub 2007 Jan 17.
2006 Oct
Tsuruoka S, Watanabe S, Purkerson JM, Fujimura A, Schwartz GJ. "Endothelin and nitric oxide mediate adaptation of the cortical collecting duct to metabolic acidosis." American journal of physiology. Renal physiology. 2006 Oct; 291(4):F866-73. Epub 2006 May 16.
2005 Oct
Purkerson JM, Smith RS, Pollock SJ, Phipps RP. "The TRAF6, but not the TRAF2/3, binding domain of CD40 is required for cytokine production in human lung fibroblasts." European journal of immunology. 2005 Oct; 35(10):2920-8.
2005 May
Purkerson JM, Schwartz GJ. "Expression of membrane-associated carbonic anhydrase isoforms IV, IX, XII, and XIV in the rabbit: induction of CA IV and IX during maturation." American journal of physiology. Regulatory, integrative and comparative physiology. 2005 May; 288(5):R1256-63.
2003 Jun
Tsuruoka S, Schwartz GJ, Wakaumi M, Nishiki K, Yamamoto H, Purkerson JM, Fujimura A. "Nitric oxide production modulates cyclosporin A-induced distal renal tubular acidosis in the rat." The Journal of pharmacology and experimental therapeutics. 2003 Jun; 305(3):840-5. Epub 2003 Mar 06.
2000 Feb
Hwang Y, Nahm MH, Briles DE, Thomas D, Purkerson JM. "Acquired, but not innate, immune responses to Streptococcus pneumoniae are compromised by neutralization of CD40L." Infection and immunity. 2000 Feb; 68(2):511-7.
2000 Jan 15
Evans DE, Munks MW, Purkerson JM, Parker DC. "Resting B lymphocytes as APC for naive T lymphocytes: dependence on CD40 ligand/CD40." The Journal of immunology : official journal of the American Association of Immunologists. 2000 Jan 15; 164(2):688-97.
1998 Mar 1
Purkerson JM, Parker DC. "Differential coupling of membrane Ig and CD40 to the extracellularly regulated kinase signaling pathway." The Journal of immunology : official journal of the American Association of Immunologists. 1998 Mar 1; 160(5):2121-9.
Weber JD; Isakson PC; Purkerson JM. "IL-5 receptor expression and Ig secretion from murine B lymphocytes requires coordinated signaling by membrane Ig , IL-4, and IL-5." Journal of Immunology. 1996; 157(10): 4428-35.
1994 Jun 1
Purkerson JM, Isakson PC. "Independent regulation of DNA recombination and immunoglobulin (Ig) secretion during isotype switching to IgG1 and IgE." The Journal of experimental medicine. 1994 Jun 1; 179(6):1877-83.
1992 Nov
Purkerson J, Isakson P. "A two-signal model for regulation of immunoglobulin isotype switching." FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1992 Nov; 6(14):3245-52.
1992 Apr 1
Purkerson JM, Isakson PC. "Interleukin 5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglobulin (Ig) G1 and IgE." The Journal of experimental medicine. 1992 Apr 1; 175(4):973-82.
Catron KM; Purkerson JM; Isakson PC; Bender TP. "Constitutive versus cell cycle regulation of c-myb mRNA expression correlates with developmental stages in murine B lymphoid tumors." Journal of Immunology. 1992; 148(3): 934-42.
1991 Dec 15
Isakson PC, Purkerson J, Catron K, Bender TP. "A novel method for synchronizing a B cell lymphoma." Journal of immunological methods. 1991 Dec 15; 145(1-2):137-42.
1991 Mar
Purkerson JM, Isakson PC. "Isotype switching in anti-immunoglobulin-activated B lymphoblasts: differential requirements for interleukin 4 and other lymphokines to elicit membrane vs. secreted IgG1." European journal of immunology. 1991 Mar; 21(3):707-14.
Catron KM, Toth CR, Purkerson J, Isakson P, Bender TP. "Constitutive and cell cycle regulated expression of c-myc mRNA is related to the state of differentiation in murine B-lymphoid tumors." Current topics in microbiology and immunology. 1990 166:197-202.
1988 Sep 1
Purkerson JM, Newberg M, Wise G, Lynch KR, Isakson PC. "Interleukin 5 and interleukin 2 cooperate with interleukin 4 to induce IgG1 secretion from anti-Ig-treated B cells." The Journal of experimental medicine. 1988 Sep 1; 168(3):1175-80.


Carolyn J. Baglole, Richard P. Phipps, Jeffrey M. Purkerson, Patricia J. Sime. "Targeting of the CD40-CD40 (CD154) Ligand System as Therapeutic Intervention for the Tratment of Atherosclerosis". Trends in Atherosclerosis Research. Leon V. Clark. New York, NY: Nova Science Publishers Inc., 2004.
Parker DC, Purkerson JM. "B-cell activation and maturation to immunoglobulin secretion". Cytokine regulation of humoral immunity: Basic and clinical aspects. CM Snapper. New York, NY: John Wiley & Sons, 1996. 99