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Jeffrey Michael Purkerson, Ph.D.


Showing all 25 journal articles & 2 books available

Journal Articles

Saxena V, Hains DS, Ketz J, Chanley M, Spencer JD, Becknell B, Pierce KR, Nelson RD, Purkerson JM, Schwartz GJ, Schwaderer AL. "Cell-specific qRT-PCR of renal epithelial cells reveals a novel innate immune signature in murine collecting duct." American journal of physiology. Renal physiology.. 2018 Oct 1; 315(4):F812-F823. Epub 2017 May 03.

Peng H, Purkerson JM, Schwaderer AL, Schwartz GJ. "Metabolic acidosis stimulates the production of the antimicrobial peptide cathelicidin in rabbit urine." American journal of physiology. Renal physiology.. 2017 Nov 1; 313(5):F1061-F1067. Epub 2017 Jul 26.

Schwartz GJ, Gao X, Tsuruoka S, Purkerson JM, Peng H, D'Agati V, Picard N, Eladari D, Al-Awqati Q. "SDF1 induction by acidosis from principal cells regulates intercalated cell subtype distribution." The Journal of clinical investigation.. 2015 Oct 26; 125(12):4365-74. Epub 2015 Oct 26.

Purkerson JM, Schwaderer AL, Nakamori A, Schwartz GJ. "Distinct ?-intercalated cell morphology and its modification by acidosis define regions of the collecting duct." American journal of physiology. Renal physiology.. 2015 Sep 1; 309(5):F464-73. Epub 2015 Jun 17.

Chambrey, R.; Kurth. I.;Peti-Peterdi J.;Houillier, P.;Purkerson, J.;Leviel,F.;Zbedik, A.;Schwartz,G.J.;Huebner,C.;Eladari, D. "Renal Intercalated cells are rather energized by a proton than a sodium-pump." PNAS. 2013; .

Purkerson JM; Tsuruoka S; Suter DZ; Nakamori A; Schwartz GJ. "Adaptation to metabolic acidosis and its recovery are associated with changes in anion exchanger distribution and expression in the cortical collecting duct". Kindney International. 2010; 78(10): 993-1005.

Peng H, Vijayakumar S, Schiene-Fischer C, Li H, Purkerson JM, Malesevic M, Liebscher J, Al-Awqati, Schwartz GJ. "Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation." Journal of Biological Chemistry. 2009; 284(10): 6465-75.

Peng H; Vijayakumar S; Schiene-Fischer C; Li H; Purkerson JM; Malesevic M; Liebscher J; Al-Awqati Q; Schwartz GJ. "Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation." Journal of Biological Chemistry. 2008; 284(10): 6465-75.

Purkerson JM, Kittelberger AM, Schwartz GJ. "Basolateral carbonic anhydrase IV in the proximal tubule is a glycosylphosphatidylinositol-anchored protein." Kidney international.. 2007 Mar 0; 71(5):407-16. Epub 2007 Jan 17.

Tsuruoka S, Watanabe S, Purkerson JM, Fujimura A, Schwartz GJ. "Endothelin and nitric oxide mediate adaptation of the cortical collecting duct to metabolic acidosis." American journal of physiology. Renal physiology.. 2006 Oct 0; 291(4):F866-73. Epub 2006 May 16.

Purkerson JM, Smith RS, Pollock SJ, Phipps RP. "The TRAF6, but not the TRAF2/3, binding domain of CD40 is required for cytokine production in human lung fibroblasts." European journal of immunology.. 2005 Oct 0; 35(10):2920-8.

Purkerson JM, Schwartz GJ. "Expression of membrane-associated carbonic anhydrase isoforms IV, IX, XII, and XIV in the rabbit: induction of CA IV and IX during maturation." American journal of physiology. Regulatory, integrative and comparative physiology.. 2005 May 0; 288(5):R1256-63.

Tsuruoka S, Schwartz GJ, Wakaumi M, Nishiki K, Yamamoto H, Purkerson JM, Fujimura A. "Nitric oxide production modulates cyclosporin A-induced distal renal tubular acidosis in the rat." The Journal of pharmacology and experimental therapeutics.. 2003 Jun 0; 305(3):840-5. Epub 2003 Mar 06.

Hwang Y, Nahm MH, Briles DE, Thomas D, Purkerson JM. "Acquired, but not innate, immune responses to Streptococcus pneumoniae are compromised by neutralization of CD40L." Infection and immunity.. 2000 Feb 0; 68(2):511-7.

Evans DE, Munks MW, Purkerson JM, Parker DC. "Resting B lymphocytes as APC for naive T lymphocytes: dependence on CD40 ligand/CD40." The Journal of immunology : official journal of the American Association of Immunologists.. 2000 Jan 15; 164(2):688-97.

Purkerson JM, Parker DC. "Differential coupling of membrane Ig and CD40 to the extracellularly regulated kinase signaling pathway." The Journal of immunology : official journal of the American Association of Immunologists.. 1998 Mar 1; 160(5):2121-9.

Weber JD; Isakson PC; Purkerson JM. "IL-5 receptor expression and Ig secretion from murine B lymphocytes requires coordinated signaling by membrane Ig , IL-4, and IL-5." Journal of Immunology. 1996; 157(10): 4428-35.

Purkerson JM, Isakson PC. "Independent regulation of DNA recombination and immunoglobulin (Ig) secretion during isotype switching to IgG1 and IgE." The Journal of experimental medicine.. 1994 Jun 1; 179(6):1877-83.

Purkerson J, Isakson P. "A two-signal model for regulation of immunoglobulin isotype switching." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 1992 Nov 0; 6(14):3245-52.

Purkerson JM, Isakson PC. "Interleukin 5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglobulin (Ig) G1 and IgE." The Journal of experimental medicine.. 1992 Apr 1; 175(4):973-82.

Catron KM; Purkerson JM; Isakson PC; Bender TP. "Constitutive versus cell cycle regulation of c-myb mRNA expression correlates with developmental stages in murine B lymphoid tumors." Journal of Immunology. 1992; 148(3): 934-42.

Isakson PC, Purkerson J, Catron K, Bender TP. "A novel method for synchronizing a B cell lymphoma." Journal of immunological methods.. 1991 Dec 15; 145(1-2):137-42.

Purkerson JM, Isakson PC. "Isotype switching in anti-immunoglobulin-activated B lymphoblasts: differential requirements for interleukin 4 and other lymphokines to elicit membrane vs. secreted IgG1." European journal of immunology.. 1991 Mar 0; 21(3):707-14.

Catron KM, Toth CR, Purkerson J, Isakson P, Bender TP. "Constitutive and cell cycle regulated expression of c-myc mRNA is related to the state of differentiation in murine B-lymphoid tumors." Current topics in microbiology and immunology.. 1990 166:197-202.

Purkerson JM, Newberg M, Wise G, Lynch KR, Isakson PC. "Interleukin 5 and interleukin 2 cooperate with interleukin 4 to induce IgG1 secretion from anti-Ig-treated B cells." The Journal of experimental medicine.. 1988 Sep 1; 168(3):1175-80.

Books & Chapters

Chapter Title: Targeting of the CD40-CD40 (CD154) Ligand System as Therapeutic Intervention for the Treatment of Atherosclerosis
Book Title: Trends in Atherosclerosis Research
Author List: Carolyn J. Baglole, Richard P. Phipps, Jeffrey M. Purkerson, Patricia J. Sime
Edited By: Leon V. Clark
Published By: Nova Science Publishers Inc.2004 in New York, NY

Chapter Title: B-cell activation and maturation to immunoglobulin secretion
Book Title: Cytokine regulation of humoral immunity: Basic and clinical aspects
Author List: Parker DC, Purkerson JM
Edited By: CM Snapper
Published By: John Wiley & Sons1996 in New York, NY