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Robert H. Dworkin, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-8214

Fax: (585) 244-7271

Faculty Appointments

Biography

Professional Background

1. Director, Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION), a public-private partnership with the U.S. Food and Drug Administration (FDA) [www.acttion.org]
2. Special Government Employee, Center for Drug Evaluation and Research, FDA
3. Professional Advisory Board, American Chronic Pain Association
4. Selection Committee, David Sackett Trial of the Year, Society for Clinical Trials
5. Associate Editor: Pain; Editorial Boards: Canadian Journal of Pain, Journal of Pain

Research

My major research interests are (1) methodologic aspects of analgesic clinical trials and (2) treatment and prevention of chronic neuropathic and musculoskeletal pain. The primary focus of my current research involves the identification of factors that increase the assay sensitivity of randomized clinical trials to detect differences between an efficacious treatment and a placebo control or comparison intervention. In ongoing studies, we are evaluating the research designs and methods, clinical outcome assessments, and statistical analyses used in clinical trials of treatments for acute and chronic pain. These studies and other efforts to improve the efficiency and informativeness of clinical trials of analgesic, addiction, anesthesiology, and peripheral neuropathy interventions are being conducted under the auspices of the ACTTION public-private partnership with the FDA, of which I serve as Director.

Current Funding (as Principal Investigator)
1. NIH/NINDS, U24 NS113850 (9/30/19-8/31/24): Clinical coordinating center for the HEAL initiative early phase pain investigation clinical network.
2. FDA, U01 FD005936 (9/15/16-8/31/21): Analgesic, anesthetic, and addiction clinical trial translations, innovations, opportunities, and networks (ACTTION) public-private partnership.

Credentials

Education

1971
BA | University of Pennsylvania
Psychology, Sociology

1977
PhD | Harvard University
Psychology

Awards

2020
John D. Loeser Award
Sponsor: International Association for the Study of Pain

2018
Founders Award
Sponsor: American Academy of Pain Medicine

2018
Raymond W. Houde Award
Sponsor: Eastern Pain Association

2015
Mitchell B. Max Award for Neuropathic Pain
Sponsor: American Academy of Neurology

2014
John and Emma Bonica Public Service Award
Sponsor: American Pain Society

2011
John J. Bonica Award
Sponsor: Eastern Pain Association

2008
Frontiers in Pain Lecture
Sponsor: McGill University

2007
Advisory Committee Service Award
Sponsor: US Food and Drug Administration

2007
Gunn-Loke Lecture
Sponsor: University of Washington

2005
Wilbert Fordyce Clinical Investigator Award
Sponsor: American Pain Society

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Publications

Journal Articles

10/14/2020
Freeman R, Gewandter JS, Faber CG, Gibbons C, Haroutounian S, Lauria G, Levine T, Malik RA, Singleton JR, Smith AG, Bell J, Dworkin RH, Feldman E, Herrmann DN, Hoke A, Kolb N, Mansikka H, Oaklander AL, Peltier A, Polydefkis M, Ritt E, Russell JW, Sainati S, Steiner D, Treister R, Üçeyler N. "Idiopathic distal sensory polyneuropathy: ACTTION diagnostic criteria." Neurology.. 2020 Oct 14; Epub 2020 Oct 14.

9/29/2020
Haroutounian S, Todorovic MS, Leinders M, Campagnolo M, Gewandter JS, Dworkin RH, Freeman R. "Diagnostic criteria for idiopathic small fiber neuropathy: A systematic review." Muscle & nerve.. 2020 Sep 29; Epub 2020 Sep 29.

9/2020
Smith SM, Fava M, Jensen MP, Mbowe OB, McDermott MP, Turk DC, Dworkin RH. "John D. Loeser Award Lecture: Size does matter, but it isn't everything: the challenge of modest treatment effects in chronic pain clinical trials." Pain.. 2020 Sep 0; 161 Suppl 1:S3-S13.

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