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Lianping Xing, B.Med., Ph.D.

Publications

Showing all 130 journal articles & 3 books available

Journal Articles

9/2017
Huang QQ, Birket R, Doyle RE, Haines GK, Perlman H, Shi B, Homan P, Xing L, Pope RM. "Association of Increased F4/80 Macrophages With Suppression of Serum-Transfer Arthritis in Mice With Reduced FLIP in Myeloid Cells." Arthritis & rheumatology.. 2017 Sep 0; 69(9):1762-1771. Epub 2017 Aug 01.

7/2017
Sun W, Zhang H, Wang H, Chiu YG, Ritchlin CT, Kiernan A, Boyce BF, Xing L. "Targeting Notch-Activated M1 Macrophages Attenuates Joint Tissue Damage in a Mouse Model of Inflammatory Arthritis." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2017 Jul 0; 32(7):1469-1480. Epub 2017 Apr 10.

6/2017
Bouta EM, Kuzin I, de Mesy Bentley K, Wood RW, Rahimi H, Ji RC, Ritchlin CT, Bottaro A, Xing L, Schwarz EM. "Brief Report: Treatment of Tumor Necrosis Factor-Transgenic Mice With Anti-Tumor Necrosis Factor Restores Lymphatic Contractions, Repairs Lymphatic Vessels, and May Increase Monocyte/Macrophage Egress." Arthritis & rheumatology.. 2017 Jun 0; 69(6):1187-1193. Epub 2017 Apr 04.

6/2017
Lawal RA, Zhou X, Batey K, Hoffman CM, Georger MA, Radtke F, Hilton MJ, Xing L, Frisch BJ, Calvi LM. "The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2017 Jun 0; 32(6):1320-1331. Epub 2017 Mar 09.

5/23/2017
Xing L, Higuma T, Wang Z, Aguirre AD, Mizuno K, Takano M, Dauerman HL, Park SJ, Jang Y, Kim CJ, Kim SJ, Choi SY, Itoh T, Uemura S, Lowe H, Walters DL, Barlis P, Lee S, Lerman A, Toma C, Tan JWC, Yamamoto E, Bryniarski K, Dai J, Zanchin T, Zhang S, Yu B, Lee H, Fujimoto J, Fuster V, Jang IK. "Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study." Journal of the American College of Cardiology.. 2017 May 23; 69(20):2502-2513.

5/2017
Wang W, Wang H, Zhou X, Li X, Sun W, Dellinger M, Boyce BF, Xing L. "Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2017 May 0; 32(5):939-950. Epub 2017 Jan 31.

3/2017
Liu J, Li X, Zhang H, Gu R, Wang Z, Gao Z, Xing L. "Ubiquitin E3 ligase Itch negatively regulates osteoblast function by promoting proteasome degradation of osteogenic proteins." Bone & joint research.. 2017 Mar 0; 6(3):154-161.

2/1/2017
Li X, Sun W, Li J, Wang M, Zhang H, Pei L, Boyce BF, Wang Z, Xing L. "Clomipramine causes osteoporosis by promoting osteoclastogenesis via E3 ligase Itch, which is prevented by Zoledronic acid." Scientific reports.. 2017 Feb 1; 7:41358. Epub 2017 Feb 01.

2017
Xu H, Bouta EM, Wood RW, Schwarz EM, Wang Y, Xing L. "Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis." Bone research.. 2017 5:17012. Epub 2017 Jun 13.

12/4/2016
Li J, Chen Y, Zhang L, Xing L, Xu H, Wang Y, Shi Q, Liang Q. "Total saponins of panaxnotoginseng promotes lymphangiogenesis by activation VEGF-C expression of lymphatic endothelial cells." Journal of ethnopharmacology.. 2016 Dec 4; 193:293-302. Epub 2016 Aug 21.

10/1/2016
Huang QQ, Hossain MM, Sun W, Xing L, Pope RM, Jin JP. "Deletion of calponin 2 in macrophages attenuates the severity of inflammatory arthritis in mice." American journal of physiology. Cell physiology.. 2016 Oct 1; 311(4):C673-C685. Epub 2016 Aug 03.

9/1/2016
Rahimi H, Bell R, Bouta EM, Wood RW, Xing L, Ritchlin CT, Schwarz EM. "Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential." Arthritis research & therapy.. 2016 Sep 1; 18:194. Epub 2016 Sep 01.

9/2016
Zhang H, Sun W, Li X, Wang M, Boyce BF, Hilton MJ, Xing L. "Use of Hes1-GFP reporter mice to assess activity of the Hes1 promoter in bone cells under chronic inflammation." Bone.. 2016 Sep 0; 90:80-9. Epub 2016 Jun 04.

4/2016
Meednu N, Zhang H, Owen T, Sun W, Wang V, Cistrone C, Rangel-Moreno J, Xing L, Med B, Anolik JH. "Production of RANKL by Memory B Cells: A Link Between B Cells and Bone Erosion in Rheumatoid Arthritis." Arthritis & rheumatology.. 2016 Apr 0; 68(4):805-16.

3/12/2016
Liang Q, Ju Y, Chen Y, Wang W, Li J, Zhang L, Xu H, Wood RW, Schwarz EM, Boyce BF, Wang Y, Xing L. "Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice." Arthritis research & therapy.. 2016 Mar 12; 18:62. Epub 2016 Mar 12.

2016
Chen Y, Li J, Li Q, Wang T, Xing L, Xu H, Wang Y, Shi Q, Zhou Q, Liang Q. "Du-Huo-Ji-Sheng-Tang Attenuates Inflammation of TNF-Tg Mice Related to Promoting Lymphatic Drainage Function." Evidence-based complementary and alternative medicine : eCAM.. 2016 2016:7067691. Epub 2016 Apr 27.

9/2015
Liang QQ, Shi Q, Wood RW, Xing LP, Wang YJ. "Peri-articular lymphatic system and "Bi" theory of Chinese medicine in the pathogenesis and treatment of arthritis." Chinese journal of integrative medicine.. 2015 Sep 0; 21(9):648-55. Epub 2015 Oct 03.

4/2015
Shu L, Beier E, Sheu T, Zhang H, Zuscik MJ, Puzas EJ, Boyce BF, Mooney RA, Xing L. "High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment." Calcified tissue international.. 2015 Apr 0; 96(4):313-23. Epub 2015 Feb 13.

3/27/2015
Boyce BF, Xiu Y, Li J, Xing L, Yao Z. "NF-?B-Mediated Regulation of Osteoclastogenesis." Endocrinology and metabolism.. 2015 Mar 27; 30(1):35-44.

2/2015
Bouta EM, Li J, Ju Y, Brown EB, Ritchlin CT, Xing L, Schwarz EM. "The role of the lymphatic system in inflammatory-erosive arthritis." Seminars in cell & developmental biology.. 2015 Feb 0; 38:90-7. Epub 2015 Jan 15.

10/2014
Wang Z, Wang J, Li X, Xing L, Ding Y, Shi P, Zhang Y, Guo S, Shu X, Shan B. "Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2." International journal of oncology.. 2014 Oct 0; 45(4):1469-78. Epub 2014 Jul 17.

5/2014
Cui HB, Ge HE, Bai XY, Zhang W, Zhang YY, Wang J, Li X, Xing LP, Guo SH, Wang ZY. "Effect of neoadjuvant chemotherapy combined with hyperthermic intraperitoneal perfusion chemotherapy on advanced gastric cancer." Experimental and therapeutic medicine.. 2014 May 0; 7(5):1083-1088. Epub 2014 Mar 04.

4/2014
Yao Z, Li Y, Yin X, Dong Y, Xing L, Boyce BF. "NF-?B RelB negatively regulates osteoblast differentiation and bone formation." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2014 Apr 0; 29(4):866-77.

3/2014
Juneja SC, Vonica A, Zeiss C, Lezon-Geyda K, Yatsula B, Sell DR, Monnier VM, Lin S, Ardito T, Eyre D, Reynolds D, Yao Z, Awad HA, Yu H, Wilson M, Honnons S, Boyce BF, Xing L, Zhang Y, Perkins AS. "Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia." Bone.. 2014 Mar 0; 60:148-61. Epub 2013 Dec 04.

3/2014
Shi J, Liang Q, Zuscik M, Shen J, Chen D, Xu H, Wang YJ, Chen Y, Wood RW, Li J, Boyce BF, Xing L. "Distribution and alteration of lymphatic vessels in knee joints of normal and osteoarthritic mice." Arthritis & rheumatology.. 2014 Mar 0; 66(3):657-66.

1/2014
Wang B, Jin H, Zhu M, Li J, Zhao L, Zhang Y, Tang D, Xiao G, Xing L, Boyce BF, Chen D. "Chondrocyte ?-catenin signaling regulates postnatal bone remodeling through modulation of osteoclast formation in a murine model." Arthritis & rheumatology.. 2014 Jan 0; 66(1):107-20.

2014
Xing L, Boyce BF. "RANKL-based osteoclastogenic assays from murine bone marrow cells." Methods in molecular biology.. 2014 1130:307-313.

2014
Brown ML, Yukata K, Farnsworth CW, Chen DG, Awad H, Hilton MJ, O'Keefe RJ, Xing L, Mooney RA, Zuscik MJ. "Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus." PloS one.. 2014 9(6):e99656. Epub 2014 Jun 09.

12/2013
Xing L, Chen D, Boyce BF. "Mice Deficient in NF-?B p50 and p52 or RANK Have Defective Growth Plate Formation and Post-natal Dwarfism." Bone research.. 2013 Dec 0; 1(4):336-45. Epub 2013 Dec 31.

11/18/2013
Shi J, Liang Q, Zuscik M, Shen J, Chen D, Xu H, Wang Y, Chen Y, Wood RW, Li J, Boyce BF, Xing L. "Alteration of lymphatic vessel and function in osteoarthritic joints." Arthritis and rheumatism.. 2013 Nov 18; Epub 2013 Nov 18.

11/2013
Inzana JA, Kung M, Shu L, Hamada D, Xing LP, Zuscik MJ, Awad HA, Mooney RA. "Immature mice are more susceptible to the detrimental effects of high fat diet on cancellous bone in the distal femur." Bone.. 2013 Nov 0; 57(1):174-83. Epub 2013 Aug 14.

9/2013
Shu L, Zhang H, Boyce B, Xing L. "Ubiquitin E3 ligase Wwp1 negatively regulates osteoblast function by inhibiting osteoblast differentiation and migration." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2013 Sep 0; 28(9):1925-35.

9/2013
Ju Y, Li J, Xie C, Ritchlin CT, Xing L, Hilton MJ, Schwarz EM. "Troponin T3 expression in skeletal and smooth muscle is required for growth and postnatal survival: characterization of Tnnt3(tm2a(KOMP)Wtsi) mice." Genesis : the journal of genetics and development.. 2013 Sep 0; 51(9):667-75. Epub 2013 Jul 09.

8/2/2013
Zhang H, Wu C, Matesic LE, Li X, Wang Z, Boyce BF, Xing L. "Ubiquitin E3 ligase Itch negatively regulates osteoclast formation by promoting deubiquitination of tumor necrosis factor (TNF) receptor-associated factor 6." The Journal of biological chemistry.. 2013 Aug 2; 288(31):22359-68. Epub 2013 Jun 19.

8/2013
Zhang H, Xing L. "Ubiquitin e3 ligase itch negatively regulates osteoblast differentiation from mesenchymal progenitor cells." Stem cells.. 2013 Aug 0; 31(8):1574-83.

1/2013
Li J, Ju Y, Bouta EM, Xing L, Wood RW, Kuzin I, Bottaro A, Ritchlin CT, Schwarz EM. "Efficacy of B cell depletion therapy for murine joint arthritis flare is associated with increased lymphatic flow." Arthritis and rheumatism.. 2013 Jan 0; 65(1):130-8.

2013
Bouta EM, Ju Y, Rahimi H, de Mesy-Bentley KL, Wood RW, Xing L, Schwarz EM. "Power Doppler ultrasound phenotyping of expanding versus collapsed popliteal lymph nodes in murine inflammatory arthritis." PloS one.. 2013 8(9):e73766. Epub 2013 Sep 09.

2013
Xing L, Chen D, Boyce BF. "Mice Deficient in NF-?B p50 and p52 or RANK Have Defective Growth Plate Formation and Post-natal Dwarfism." Bone research.. 2013 4:336-345.

12/18/2012
Xing L, Xiu Y, Boyce BF. "Osteoclast fusion and regulation by RANKL-dependent and independent factors." World journal of orthopedics. 2012 Dec 18; 3(12):212-22.

11/2012
Takahata M, Maher JR, Juneja SC, Inzana J, Xing L, Schwarz EM, Berger AJ, Awad HA. "Mechanisms of bone fragility in a mouse model of glucocorticoid-treated rheumatoid arthritis: implications for insufficiency fracture risk." Arthritis and rheumatism.. 2012 Nov 0; 64(11):3649-59.

6/2012
Ju Y, Rahimi H, Li J, Wood RW, Xing L, Schwarz EM. "Validation of 3-dimensional ultrasound versus magnetic resonance imaging quantification of popliteal lymph node volume as a biomarker of erosive inflammatory arthritis in mice." Arthritis and rheumatism.. 2012 Jun 0; 64(6):2048-50. Epub 2012 Feb 21.

4/2012
Subik K, Shu L, Wu C, Liang Q, Hicks D, Boyce B, Schiffhauer L, Chen D, Chen C, Tang P, Xing L. "The ubiquitin E3 ligase WWP1 decreases CXCL12-mediated MDA231 breast cancer cell migration and bone metastasis." Bone.. 2012 Apr 0; 50(4):813-23. Epub 2012 Jan 11.

4/2012
Zhao C, Xiu Y, Ashton J, Xing L, Morita Y, Jordan CT, Boyce BF. "Noncanonical NF-?B signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions." Stem cells.. 2012 Apr 0; 30(4):709-18.

1/12/2012
Frisch BJ, Ashton JM, Xing L, Becker MW, Jordan CT, Calvi LM. "Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia." Blood.. 2012 Jan 12; 119(2):540-50. Epub 2011 Sep 28.

12/1/2011
Boyce B, Xing L. "Src inhibitors in the treatment of metastatic bone disease: rationale and clinical data." Clinical investigation.. 2011 Dec 1; 1(12):1695-1706.

12/2011
Bouta EM, Wood RW, Perry SW, Brown EB, Ritchlin CT, Xing L, Schwarz EM. "Measuring intranodal pressure and lymph viscosity to elucidate mechanisms of arthritic flare and therapeutic outcomes." Annals of the New York Academy of Sciences.. 2011 Dec 0; 1240:47-52.

10/2011
Zhao L, Huang J, Zhang H, Wang Y, Matesic LE, Takahata M, Awad H, Chen D, Xing L. "Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1." Stem cells.. 2011 Oct 0; 29(10):1601-10.

8/31/2011
Li J, Zhou Q, Wood R, Kuzin I, Bottaro A, Ritchlin C, Xing L, Schwarz E. "CD23(+)/CD21(hi) B-cell translocation and ipsilateral lymph node collapse is associated with asymmetric arthritic flare in TNF-Tg mice." Arthritis research & therapy.. 2011 Aug 31; 13(4):R138. Epub 2011 Aug 31.

8/2011
Zhou Q, Guo R, Wood R, Boyce BF, Liang Q, Wang YJ, Schwarz EM, Xing L. "Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice." Arthritis and rheumatism.. 2011 Aug 0; 63(8):2318-28.

6/1/2010
Li J, Kuzin I, Moshkani S, Proulx ST, Xing L, Skrombolas D, Dunn R, Sanz I, Schwarz EM, Bottaro A. "Expanded CD23(+)/CD21(hi) B cells in inflamed lymph nodes are associated with the onset of inflammatory-erosive arthritis in TNF-transgenic mice and are targets of anti-CD20 therapy." The Journal of immunology : official journal of the American Association of Immunologists.. 2010 Jun 1; 184(11):6142-50. Epub 2010 Apr 30.

6/1/2010
Xing L, Zhang M, Chen D. "Smurf control in bone cells." Journal of cellular biochemistry.. 2010 Jun 1; 110(3):554-63.

6/2010
Zhao L, Huang J, Guo R, Wang Y, Chen D, Xing L. "Smurf1 inhibits mesenchymal stem cell proliferation and differentiation into osteoblasts through JunB degradation." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2010 Jun 0; 25(6):1246-56.

5/20/2010
Subik K, Lee JF, Baxter L, Strzepek T, Costello D, Crowley P, Xing L, Hung MC, Bonfiglio T, Hicks DG, Tang P. "The Expression Patterns of ER, PR, HER2, CK5/6, EGFR, Ki-67 and AR by Immunohistochemical Analysis in Breast Cancer Cell Lines." Breast cancer : basic and clinical research.. 2010 May 20; 4:35-41. Epub 2010 May 20.

4/2010
Mensah KA, Mathian A, Ma L, Xing L, Ritchlin CT, Schwarz EM. "Mediation of nonerosive arthritis in a mouse model of lupus by interferon-alpha-stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis." Arthritis and rheumatism.. 2010 Apr 0; 62(4):1127-37.

3/2010
Li D, Gromov K, Proulx ST, Xie C, Li J, Crane DP, Søballe K, O'Keefe RJ, Awad HA, Xing L, Schwarz EM. "Effects of antiresorptive agents on osteomyelitis: novel insights into the pathogenesis of osteonecrosis of the jaw." Annals of the New York Academy of Sciences.. 2010 Mar 0; 1192:84-94.

3/2010
Boyce BF, Yao Z, Xing L. "Functions of nuclear factor kappaB in bone." Annals of the New York Academy of Sciences.. 2010 Mar 0; 1192:367-75.

2/2010
Huang J, Zhao L, Xing L, Chen D. "MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation." Stem cells.. 2010 Feb 0; 28(2):357-64.

2010
Schwarz EM, Proulx ST, Ritchlin CT, Boyce BF, Xing L. "The role of bone marrow edema and lymphangiogenesis in inflammatory-erosive arthritis." Advances in experimental medicine and biology.. 2010 658:1-10.

11/1/2009
Zhang M, Yan Y, Lim YB, Tang D, Xie R, Chen A, Tai P, Harris SE, Xing L, Qin YX, Chen D. "BMP-2 modulates beta-catenin signaling through stimulation of Lrp5 expression and inhibition of beta-TrCP expression in osteoblasts." Journal of cellular biochemistry.. 2009 Nov 1; 108(4):896-905.

11/2009
Xing L. "Regulation of osteoclast precursors in inflammatory bone loss." Current opinion in investigational drugs (London, England : 2000). 2009 Nov 0; 10(11):1195-203.

10/2009
Yao Z, Xing L, Boyce BF. "NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism." The Journal of clinical investigation.. 2009 Oct 0; 119(10):3024-34. Epub 2009 Sep 21.

9/2009
Guo R, Zhou Q, Proulx ST, Wood R, Ji RC, Ritchlin CT, Pytowski B, Zhu Z, Wang YJ, Schwarz EM, Xing L. "Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis." Arthritis and rheumatism.. 2009 Sep 0; 60(9):2666-76.

8/2009
Jonason JH, Xiao G, Zhang M, Xing L, Chen D. "Post-translational Regulation of Runx2 in Bone and Cartilage." Journal of dental research.. 2009 Aug 0; 88(8):693-703.

2009
Boyce BF, Yao Z, Xing L. "Osteoclasts have multiple roles in bone in addition to bone resorption." Critical reviews in eukaryotic gene expression.. 2009 19(3):171-80.

9/2008
Xing L, Ji RC. "Lymphangiogenesis, myeloid cells and inflammation." Expert review of clinical immunology.. 2008 Sep 0; 4(5):599-613.

8/22/2008
Guo R, Yamashita M, Zhang Q, Zhou Q, Chen D, Reynolds DG, Awad HA, Yanoso L, Zhao L, Schwarz EM, Zhang YE, Boyce BF, Xing L. "Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins." The Journal of biological chemistry.. 2008 Aug 22; 283(34):23084-92. Epub 2008 Jun 19.

7/2008
Proulx ST, Kwok E, You Z, Papuga MO, Beck CA, Shealy DJ, Calvi LM, Ritchlin CT, Awad HA, Boyce BF, Xing L, Schwarz EM. "Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging." Arthritis and rheumatism.. 2008 Jul 0; 58(7):2019-29.

5/15/2008
Boyce BF, Xing L. "Functions of RANKL/RANK/OPG in bone modeling and remodeling." Archives of biochemistry and biophysics.. 2008 May 15; 473(2):139-46. Epub 2008 Mar 25.

5/9/2008
Zhang Q, Guo R, Lu Y, Zhao L, Zhou Q, Schwarz EM, Huang J, Chen D, Jin ZG, Boyce BF, Xing L. "VEGF-C, a lymphatic growth factor, is a RANKL target gene in osteoclasts that enhances osteoclastic bone resorption through an autocrine mechanism." The Journal of biological chemistry.. 2008 May 9; 283(19):13491-9. Epub 2008 Mar 20.

4/11/2008
Yao Z, Xing L, Qin C, Schwarz EM, Boyce BF. "Osteoclast precursor interaction with bone matrix induces osteoclast formation directly by an interleukin-1-mediated autocrine mechanism." The Journal of biological chemistry.. 2008 Apr 11; 283(15):9917-24. Epub 2008 Feb 04.

4/2008
Boyce BF, Xing L. "Bruton and Tec: new links in osteoimmunology." Cell metabolism.. 2008 Apr 0; 7(4):283-5.

3/2008
Usui M, Xing L, Drissi H, Zuscik M, O'Keefe R, Chen D, Boyce BF. "Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2008 Mar 0; 23(3):314-25.

2008
Zhang Q, Guo R, Schwarz EM, Boyce BF, Xing L. "TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood." Arthritis research & therapy.. 2008 10(2):R37. Epub 2008 Mar 27.

12/2007
Proulx ST, Kwok E, You Z, Papuga MO, Beck CA, Shealy DJ, Ritchlin CT, Awad HA, Boyce BF, Xing L, Schwarz EM. "Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography." Arthritis and rheumatism.. 2007 Dec 0; 56(12):4024-37.

11/2007
Proulx ST, Kwok E, You Z, Beck CA, Shealy DJ, Ritchlin CT, Boyce BF, Xing L, Schwarz EM. "MRI and quantification of draining lymph node function in inflammatory arthritis." Annals of the New York Academy of Sciences.. 2007 Nov 0; 1117:106-23. Epub 2007 Jul 23.

11/2007
Boyce BF, Yao Z, Zhang Q, Guo R, Lu Y, Schwarz EM, Xing L. "New roles for osteoclasts in bone." Annals of the New York Academy of Sciences.. 2007 Nov 0; 1116:245-54.

9/2007
Boyce BF, Xing L. "The RANKL/RANK/OPG pathway." Current osteoporosis reports.. 2007 Sep 0; 5(3):98-104.

6/22/2007
Yamashita T, Yao Z, Li F, Zhang Q, Badell IR, Schwarz EM, Takeshita S, Wagner EF, Noda M, Matsuo K, Xing L, Boyce BF. "NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1." The Journal of biological chemistry.. 2007 Jun 22; 282(25):18245-53. Epub 2007 May 07.

2007
Proulx, S.T.; Kwok, E.; You, Z.; Beck, C.A.; Shealy, D.J.; Ritchlin, C.T.; Boyce. B.F.; Xing, L.; Schwarz, E.M. "MRI and Quantification of Draining Lymph Node Function in Inflammatory Arthritis." Ann N Y Acad Sci. 2007; [Epub ahead of print].

2007
Boyce, B.F.; Xing, L. "Biology of RANK, RANKL, and osteoprotegerin." Arthritis Res Ther. 2007; 9(Suppl 1): S1.

2007
Boyce BF, Xing L. "Biology of RANK, RANKL, and osteoprotegerin." Arthritis research & therapy.. 2007 9 Suppl 1:S1.

2007
Zhang Q, Lu Y, Proulx ST, Guo R, Yao Z, Schwarz EM, Boyce BF, Xing L. "Increased lymphangiogenesis in joints of mice with inflammatory arthritis." Arthritis research & therapy.. 2007 9(6):R118.

12/2006
Boyce BF, Xing L. "Osteoclasts, no longer osteoblast slaves." Nature medicine.. 2006 Dec 0; 12(12):1356-8.

10/15/2006
Boyce BF, Xing L, Yao Z, Yamashita T, Shakespeare WC, Wang Y, Metcalf CA, Sundaramoorthi R, Dalgarno DC, Iuliucci JD, Sawyer TK. "SRC inhibitors in metastatic bone disease." Clinical cancer research : an official journal of the American Association for Cancer Research.. 2006 Oct 15; 12(20 Pt 2):6291s-6295s.

7/2006
Boyce BF, Schwarz EM, Xing L. "Osteoclast precursors: cytokine-stimulated immunomodulators of inflammatory bone disease." Current opinion in rheumatology.. 2006 Jul 0; 18(4):427-32.

4/28/2006
Yao Z, Li P, Zhang Q, Schwarz EM, Keng P, Arbini A, Boyce BF, Xing L. "Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression." The Journal of biological chemistry.. 2006 Apr 28; 281(17):11846-55. Epub 2006 Feb 06.

4/2006
Schwarz EM, Looney RJ, Drissi MH, O'Keefe RJ, Boyce BF, Xing L, Ritchlin CT. "Autoimmunity and bone." Annals of the New York Academy of Sciences.. 2006 Apr 0; 1068:275-83.

4/2006
Boyce BF, Xing L, Yao Z, Shakespeare WC, Wang Y, Metcalf CA, Sundaramoorthi R, Dalgarno DC, Iuliucci JD, Sawyer TK. "Future anti-catabolic therapeutic targets in bone disease." Annals of the New York Academy of Sciences.. 2006 Apr 0; 1068:447-57.

2/17/2006
Kaneki H, Guo R, Chen D, Yao Z, Schwarz EM, Zhang YE, Boyce BF, Xing L. "Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts." The Journal of biological chemistry.. 2006 Feb 17; 281(7):4326-33. Epub 2005 Dec 22.

2/10/2006
Shen R, Chen M, Wang YJ, Kaneki H, Xing L, O'keefe RJ, Chen D. "Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation." The Journal of biological chemistry.. 2006 Feb 10; 281(6):3569-76. Epub 2005 Nov 18.

12/2005
Xing L, Schwarz EM, Boyce BF. "Osteoclast precursors, RANKL/RANK, and immunology." Immunological reviews.. 2005 Dec 0; 208:19-29.

12/2005
Boyce BF, Xing L, Chen D. "Osteoprotegerin, the bone protector, is a surprising target for beta-catenin signaling." Cell metabolism.. 2005 Dec 0; 2(6):344-5.

9/2005
Zhang Q, Badell IR, Schwarz EM, Boulukos KE, Yao Z, Boyce BF, Xing L. "Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2." Arthritis and rheumatism.. 2005 Sep 0; 52(9):2708-18.

9/2005
Boyce BF, Li P, Yao Z, Zhang Q, Badell IR, Schwarz EM, O'Keefe RJ, Xing L. "TNF-alpha and pathologic bone resorption." The Keio journal of medicine.. 2005 Sep 0; 54(3):127-31.

3/18/2005
Xing L, Boyce BF. "Regulation of apoptosis in osteoclasts and osteoblastic cells." Biochemical and biophysical research communications.. 2005 Mar 18; 328(3):709-20.

2005
Schwarz, E.M.; O'Keefe, R.J.; Xing, L.; Looney, J.; and Ritchlin, C.T. "Receptor activator of nuclear kB ligand and osteoprotegerin: where are we now and what about future treatment uses?". Curr Opin Orthop. 2005; 16: 370-375.

2005
Xing, L.; and Boyce, B.F. "Regulation of apoptosis in osteoclasts and osteoblastic cells." Biochem Biophys Res Commun 709-20. 2005; 328(3): 709-20.

2005
Xing, L.; and Schwarz, E.M. "Circulating osteoclast precursors: A mechanism and a marker of erosive arthritis." Curr Rheu Rev. 2005; 1: 21-28.

2005
Boyce, B.F.; Yamashita, T.; Yao, Z.; Zhang, Q.; Li, F.; and Xing, L. "Roles for NF-?B and c-Fos in osteoclasts." J Bone Miner Metab 11-5. 2005; 23 Suppl: 11-25.

2005
Boyce BF, Yamashita T, Yao Z, Zhang Q, Li F, Xing L. "Roles for NF-kappaB and c-Fos in osteoclasts." Journal of bone and mineral metabolism. 2005 23 Suppl:11-5.

10/2004
Kapur RP, Yao Z, Iida MH, Clarke CM, Doggett B, Xing L, Boyce BF. "Malignant autosomal recessive osteopetrosis caused by spontaneous mutation of murine Rank." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2004 Oct 0; 19(10):1689-97. Epub 2004 Jul 21.

2/2004
Li P, Schwarz EM, O'Keefe RJ, Ma L, Boyce BF, Xing L. "RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2004 Feb 0; 19(2):207-13.

1/2004
Li P, Schwarz EM, O'Keefe RJ, Ma L, Looney RJ, Ritchlin CT, Boyce BF, Xing L. "Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice." Arthritis and rheumatism.. 2004 Jan 0; 50(1):265-76.

2004
Li, P.; Schwarz, E.M.; O'Keefe, R.J.; Ma, L.; Looney, J.; Ritchlin, C.T.; Boyce, B.F.; and Xing, L. "Systemic TNFa mediates an increase in peripheral CD11bhi osteoclast precursors in TNFa transgenic mice." Arthritis & Rheum. 2004; 50: 256-76.

8/1/2003
Feng JQ, Xing L, Zhang JH, Zhao M, Horn D, Chan J, Boyce BF, Harris SE, Mundy GR, Chen D. "NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro." The Journal of biological chemistry.. 2003 Aug 1; 278(31):29130-5. Epub 2003 May 20.

6/2003
Boyce BF, Xing L, Shakespeare W, Wang Y, Dalgarno D, Iuliucci J, Sawyer T. "Regulation of bone remodeling and emerging breakthrough drugs for osteoporosis and osteolytic bone metastases." Kidney international. Supplement. 2003 Jun 0; (85):S2-5.

2/2003
Xing L, Carlson L, Story B, Tai Z, Keng P, Siebenlist U, Boyce BF. "Expression of either NF-kappaB p50 or p52 in osteoclast precursors is required for IL-1-induced bone resorption." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2003 Feb 0; 18(2):260-9.

2003
Boyce, B.F.; Xing, L.; Shakespeare, W.; Wang, Y.; Dalgarno, D.; Iuliucci, J.; and Sawyer, T. "Regulation of bone remodeling and emerging breakthrough drugs for osteoporosis and osteolytic bone metastases." Kidney Int. 2003; Suppl 85: S2-5.

10/15/2002
Yeh S, Tsai MY, Xu Q, Mu XM, Lardy H, Huang KE, Lin H, Yeh SD, Altuwaijri S, Zhou X, Xing L, Boyce BF, Hung MC, Zhang S, Gan L, Chang C, Hung MC. "Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues." Proceedings of the National Academy of Sciences of the United States of America.. 2002 Oct 15; 99(21):13498-503. Epub 2002 Oct 07.

7/2002
Xing L, Bushnell TP, Carlson L, Tai Z, Tondravi M, Siebenlist U, Young F, Boyce BF. "NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2002 Jul 0; 17(7):1200-10.

2/2002
Childs LM, Paschalis EP, Xing L, Dougall WC, Anderson D, Boskey AL, Puzas JE, Rosier RN, O'Keefe RJ, Boyce BF, Schwarz EM. "In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2002 Feb 0; 17(2):192-9.

4/2001
Zhang X, Morham SG, Langenbach R, Young DA, Xing L, Boyce BF, Puzas EJ, Rosier RN, O'Keefe RJ, Schwarz EM. "Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2001 Apr 0; 16(4):660-70.

1/15/2001
Xing L, Venegas AM, Chen A, Garrett-Beal L, Boyce BF, Varmus HE, Schwartzberg PL. "Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival." Genes & development.. 2001 Jan 15; 15(2):241-53.

2001
Xing, L.; Venegas, A.M.; Chen, A.; Garrett-Beal, L.; Boyce, B.F.; Varmus, H.E.; Schwartzberg, P.L. "Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival." Genes Dev. 2001; 15: 5241-5321.

2001
Choi, J.Y.; Pratap, J.; Javed, A.; Zaidi, S.K.; Balint, E.; Xing, L.; Boyce, B.; Wilnen, A.; Lian, J.B.; Stain, J.L.; Jones, S.N.; Stain, G.S. "The C terminal subnuclear targeting signal and regulatory functions of the Runx2/Cbfa1/AML3 transcription factor are required for skeletal development." PANS. 2001; 98: 8650-55.

7/1999
Boyce BF, Xing L, Franzoso G, Siebenlist U. "Required and nonessential functions of nuclear factor-kappa B in bone cells." Bone.. 1999 Jul 0; 25(1):137-9.

2/1999
Boyce BF, Hughes DE, Wright KR, Xing L, Dai A. "Recent advances in bone biology provide insight into the pathogenesis of bone diseases." Laboratory investigation; a journal of technical methods and pathology.. 1999 Feb 0; 79(2):83-94.

1999
Tiffee, J.; Xing, L.; Nilsson, S.; Boyce, B.F. "Dental abnormalities associated with failure of tooth eruption in src knockout and op/op mice." Cal Tissue Int. 1999; 65: 53-8.

1/1998
Xing L, Karinch AM, Kauffman GL. "Mesolimbic expression of neurotensin and neurotensin receptor during stress-induced gastric mucosal injury." The American journal of physiology.. 1998 Jan 0; 274(1 Pt 2):R38-45.

12/15/1997
Franzoso G, Carlson L, Xing L, Poljak L, Shores EW, Brown KD, Leonardi A, Tran T, Boyce BF, Siebenlist U. "Requirement for NF-kappaB in osteoclast and B-cell development." Genes & development.. 1997 Dec 15; 11(24):3482-96.

11/1/1997
Schwartzberg PL, Xing L, Hoffmann O, Lowell CA, Garrett L, Boyce BF, Varmus HE. "Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice." Genes & development.. 1997 Nov 1; 11(21):2835-44.

7/21/1995
Xing L, Gopal VK, Quinn PG. "cAMP response element-binding protein (CREB) interacts with transcription factors IIB and IID." The Journal of biological chemistry.. 1995 Jul 21; 270(29):17488-93.

11/18/1994
Xing L, Quinn PG. "Three distinct regions within the constitutive activation domain of cAMP regulatory element-binding protein (CREB) are required for transcription activation." The Journal of biological chemistry.. 1994 Nov 18; 269(46):28732-6.

11/1993
Xing L, Quinn PG. "Involvement of 3',5'-cyclic adenosine monophosphate regulatory element binding protein (CREB) in both basal and hormone-mediated expression of the phosphoenolpyruvate carboxykinase (PEPCK) gene." Molecular endocrinology.. 1993 Nov 0; 7(11):1484-94.

1/1991
Xing LP, Balaban C, Seaton J, Washington J, Kauffman G. "Mesolimbic dopamine mediates gastric mucosal protection by central neurotensin." The American journal of physiology.. 1991 Jan 0; 260(1 Pt 1):G34-8.

1991
Xing, L.; Washington, J.; Seaton, J.; Kauffman, G. "Mesolimbic oxidase B inhibition reduces gastric mucosal blood flow, basal acid secretion, and cold water restraint-induced gastric mucosal injury in rats." Digestive Diseases & Sciences. 1991; 35: 61-65.

4/1990
Xing LP, King JC, Bryan RM, Kauffman GL. "Effect of neurotensin on regional cerebral glucose utilization in cold water-restrained rats." The American journal of physiology.. 1990 Apr 0; 258(4 Pt 1):G591-5.

1990
Kauffman GL, Zhang L, Xing LP, Seaton J, Colony P, Demers L. "Central neurotensin protects the mucosa by a prostaglandin-mediated mechanism and inhibits gastric acid secretion in the rat." Annals of the New York Academy of Sciences.. 1990 597:175-90.

11/1989
Zhang L, Xing LP, Demers L, Washington J, Kauffman GL. "Central neurotensin inhibits gastric acid secretion: an adrenergic mechanism in rats." Gastroenterology.. 1989 Nov 0; 97(5):1130-4.

1988
Zheng, Z.; Xing, L. "Effect of furazolidone on gut catecholamine levels in cysteamine-induced duodenal ulcer in rats." Scand J Gastroenterology. 1988; 23: 1020-1024.

Books & Chapters

2001
Chapter Title: Bone
Book Title: Yearbook of Science and Technology
Author List: Boyce BF and Xing L.
Published By: McGraw-Hill2001 in New York

2001
Chapter Title: Bone Cell Apoptosis
Book Title: Principles of Bone Biology
Author List: Boyce, B. F., Xing, L., Jilka, R. L., Bellido, T., Weinstein, R. S., Parfitt, A. M., Manolagas, S. C.
Edited By: Blezikian, J. P., Raisz, L. G., and Rodan, G. A.
Published By: Academic Press2001 in San Diego

1998
Chapter Title: Apoptosis in Bone Cells.
Book Title: Novel Approaches to Treatment of Osteoporosis
Author List: Boyce, B.F.; Hughes, D.E.; Wright, K.R.; Xing, L.; Dai, A.
Edited By: Russell, R.G.G.; Skerry, T.M.
Published By: Kollenkirchen U.1998