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Eileen M. Redmond, Ph.D.

Publications

Showing all 73 journal articles & 3 books available

Journal Articles

5/2016
Cahill PA; Redmond EM. "Vascular Endothelium; Gatekeeper of Vessel Health." Atherosclerosis. 2016; 248: 97-109.

3/2016
Ghatak S; Reveiller M; Toia L; Ivanov AI; Zhou Z; Redmond EM; Godfrey TE; Peters JH. "Bile Salts at Low pH Cause Dilation of Intercellular Spaces in In Vitro Stratified Primary Esophageal Cells, Possibly by Modulating Wnt Signaling." J Gastrointest Surg. 2016; 20(3): 500-509.

10/2015
Hatch E; Morrow D; Liu W; Cahill PA; Redmond EM. "Ethanol inhibits gamma-secretase proteolytic activity in vascular smooth muscle cells." Alcoholism: Clinical and Experimental Research. 2015; .

8/2015
Doyle AJ; Redmond EM; Gillespie DL; Knight PA; Cullen JP; Cahill PA; Morrow D. "Differential Expression of Hedgehog/Notch and Transforming Growth Factor-Beta in Human Abdominal Aortic Aneurysms." J Vasc Surg. 2015; 62(2): 464-70.

5/2015
Mooney CJ; Hakimjavadi R; Fitzpatrick E; Kennedy E; Walls D; Morrow D; Redmond EM; Cahill PA. "Hedgehog and Resident Vascular Stem Cell Fate." Stem Cells Int. 2015; 2015: 468428.

10/2014
Kennedy E; Mooney CJ; Hakimjavadi R; Fitzpatrick E; Guha S; Collins LE; Loscher CE; Morrow D; Redmond EM; Cahill PA. "Adult vascular smooth muscle cells in culture express neural stem cell markers typical of resident multipotent vascular stem cells." Cell Tissue Res. 2014; 358(1): 203-216.

10/2014
Morrow D; Hatch E; Hamm K; Cahill PA; Redmond EM. "Flk-1/KDR Mediates Ethanol-Stimulated Endothelial Cell Notch Signaling and Angiogenic Activity". Journal of Vascular Research. 2014; 51(4): 315-324.

5/2014
Gao W; Ferguson G; Connell P; Walshe T; O'Brien C; Redmond EM; Cahill PA. "Glucose attenuates hypoxia-induced changes in endothelial cell growth by inhibiting HIF-1? expression." Diab Vasc Dis Res. 2014; 11(4): 270-280.

3/2014
Kennedy E; Greene C; Hakimjavadi R; Mooney CJ; Fitzpatrick E; Collins LE; Loscher CL; Guha S; Morrow D; Redmond EM; Cahill PA. "Embryonic rat vascular smooth muscle cells revisited - a model for neonatal, neointimal vSMC or differentiated vascular stem cells?". Vascular Cell. 2014; 6(1).

2014
Redmond EM; Liu W; Hamm K, Hatch E, Cahill PA, Morrow D. "Perivascular Delivery of Notch1 siRNA Inhibits Injury-induced Arterial Remodeling." PLoS One. 2014; 9(1): e84122.

8/2013
Redmond EM; Hamm K; Cullen JP; Hatch E; Cahill PA; Morrow D. "Inhibition of Patched-1 Prevents Injury-induced Neointimal Hyperplasia." Arteriosclerosis, Thrombosis and Vascular Biology. 2013; 33(8): 1960-1964.

4/2012
Cahill PA; Redmond EM. "Alcohol and Cardiovascular Disease--Modulation of Vascular Cell Function". Nutrients. 2012; 4(4): 297-318.

3/2012
Redmond EM; Cahill PA. "The NOX-ROS connection: targeting Nox1 control of N-cadherin shedding in vascular smooth muscle cells." Cardiovasc Res. 2012; 93(3): 386-387.

12/2011
Liu W, Redmond EM, Morrow D, Cullen JP. "Differential effects of daily-moderate versus weekend-binge alcohol consumption on atherosclerotic plaque development in mice." Atherosclerosis.. 2011 Dec 0; 219(2):448-54. Epub 2011 Aug 30.

12/2011
Redmond EM, Guha S, Walls D, Cahill PA. "Investigational Notch and Hedgehog inhibitors--therapies for cardiovascular disease." Expert opinion on investigational drugs.. 2011 Dec 0; 20(12):1649-64. Epub 2011 Oct 18.

6/2011
Walshe T; Connell P; Cryan L; Ferguson G; Gardiner T; Morrow D; Redmond EM; O'Brien C; Cahill PA. "Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of Hedgehog and Notch." Invest Ophthamol Vis Sci. 2011; 52(7): 4472-83.

5/2011
Zhao J; Wang W; Hoon Ha C; Kim JY; Wong C; Redmond EM; Hamik A; Jain MK; Feng G-S; Jin ZG. "Endothelial Gab1 is crucial for postnatal angiogenesis". Arteriosclerosis, thrombosis, and vascular biology. 2011; 31(5): 1015-23.

5/2011
Guha S; Cullen JP; Morrow D; Colombo A; Lally C; Walls D; Redmond EM; Cahill PA. "Glycogen synthase kinase 3 beta (GSK-3b) positively regulates Notch signaling in vascular smooth muscle cells; role in cell proliferation and survival." Basic Res Cardiol. 2011; .

1/2011
Banerjee S; Lin C-F; Skinner K; Schiffhauer L; Peacock J; Hicks D; Redmond EM; Morrow D; Huston A; Shayne M; Langstein H; Miller-Graziano C; Strickland J; O'Donoghue L, De A. "Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression." Cancer Research. 2011; 71(2): 318-37.

12/2010
Morrow D, Cullen JP, Liu W, Cahill PA, Redmond EM. "Alcohol inhibits smooth muscle cell proliferation via regulation of the Notch signaling pathway." Arteriosclerosis, thrombosis, and vascular biology.. 2010 Dec 0; 30(12):2597-603. Epub 2010 Oct 07.

10/2009
Morrow D; Avissar NE; Toia L; Redmond EM; Watson TJ; Jones C; Raymond DP; Litle V; Godfrey T; Peters JH. "Pathogenesis of Barrett's Esophagus; Bile Acids Inhibit the Notch Signaling Pathway with Induction of CDX2 Gene Expression in Human Esophageal Cells." Surgery. 2009; 146(4): 714-721.

7/2009
Morrow D, Cullen JP, Liu W, Guha S, Sweeney C, Birney YA, Collins N, Walls D, Redmond EM, Cahill PA. "Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A." Arteriosclerosis, thrombosis, and vascular biology.. 2009 Jul 0; 29(7):1112-8. Epub 2009 Apr 30.

6/2009
Redmond EM, Morrow D, Kundimi S, Miller-Graziano CL, Cullen JP. "Acetaldehyde stimulates monocyte adhesion in a P-selectin- and TNFalpha-dependent manner." Atherosclerosis.. 2009 Jun 0; 204(2):372-80. Epub 2008 Oct 18.

2009
Redmond EM; Morrow D; Kundimi S; Miller-Grazian CL; Cullen JP. "Acetaldehyde stimulates monocyte adhesion in a P-selectin- and TNFalpha-dependent manner". Atherosclerosis. 2009; 204(2): 372-80.

12/5/2008
Morrow D, Guha S, Sweeney C, Birney Y, Walshe T, O'Brien C, Walls D, Redmond EM, Cahill PA. "Notch and vascular smooth muscle cell phenotype." Circulation research.. 2008 Dec 5; 103(12):1370-82.

11/2008
Skill NJ; Wang Y-N; Theodorakis NG; Redmond EM; Cahill PA; Sitzmann JV. "Role of cyclooxygenase isoforms in prostacyclin biosynthesis and murine pre-hepatic portal hypertension". Am J Physiol. 2008; 295(5): G953-64.

7/15/2008
Morrow D, Cullen JP, Cahill PA, Redmond EM. "Ethanol stimulates endothelial cell angiogenic activity via a Notch- and angiopoietin-1-dependent pathway." Cardiovascular research.. 2008 Jul 15; 79(2):313-21. Epub 2008 Apr 30.

11/2007
Cullen JP, Morrow D, Jin Y, von Offenberg Sweeney N, Sitzmann JV, Cahill PA, Redmond EM. "Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocytes." Atherosclerosis.. 2007 Nov 0; 195(1):e125-33. Epub 2007 May 17.

6/2007
Morrow D, Cullen JP, Cahill PA, Redmond EM. "Cyclic strain regulates the Notch/CBF-1 signaling pathway in endothelial cells: role in angiogenic activity." Arteriosclerosis, thrombosis, and vascular biology.. 2007 Jun 0; 27(6):1289-96. Epub 2007 Mar 29.

1/2007
Cummins PM; von Offenberg Sweeney N; Killeen MT; Birney YA; Redmond EM; Cahill PA. "Cyclic strain-mediated matrix metalloproteinase regulation within the vascular endothelium: A force to be reckoned with." AJP Heart and Circulatory Physiol. 2007; 292(1): H28-42.

1/2007
Morrow D, Sweeney C, Birney YA, Guha S, Collins N, Cummins PM, Murphy R, Walls D, Redmond EM, Cahill PA. "Biomechanical regulation of hedgehog signaling in vascular smooth muscle cells in vitro and in vivo." American journal of physiology. Cell physiology.. 2007 Jan 0; 292(1):C488-96. Epub 2006 Aug 30.

2007
Morrow D; Sweeney C; Guha S; Walshe T; O'Brien C; Walls D; Redmond EM; Cahill PA. "Notch signaling and vascular cell fate--how vascular cells respond to stress." Wien Klin Wochenschr. 2007; 119: 7-10.

2007
Cullen JP, Morrow D, Jin Y, Curley B, Robinson A, Sitzmann JV, Cahill PA, Redmond EM. "Resveratrol, a polyphenolic phytostilbene, inhibits endothelial monocyte chemotactic protein-1 synthesis and secretion." Journal of vascular research.. 2007 44(1):75-84. Epub 2006 Dec 21.

11/2005
Morrow D; Scheller A; Birney Y; Sweeney C; Ghua S; Cummins PM; Murphy R; Walls D; Redmond EM; Cahill PA. "Notch-mediated CBF-1/RBP-J{kappa}-dependent regulation of human vascular smooth muscle cell phenotype in vitro." Am J Physiol- Cell Physiology. 2005; 289(5): C1188-96.

10/2005
Cullen JP, Sayeed S, Jin Y, Theodorakis NG, Sitzmann JV, Cahill PA, Redmond EM. "Ethanol inhibits monocyte chemotactic protein-1 expression in interleukin-1{beta}-activated human endothelial cells." American journal of physiology. Heart and circulatory physiology.. 2005 Oct 0; 289(4):H1669-75. Epub 2005 May 20.

9/2005
Cullen JP, Sayeed S, Kim Y, Theodorakis NG, Sitzmann JV, Cahill PA, Redmond EM. "Ethanol inhibits pulse pressure-induced vascular smooth muscle cell migration by differentially modulating plasminogen activator inhibitor type 1, matrix metalloproteinase-2 and -9." Thrombosis and haemostasis.. 2005 Sep 0; 94(3):639-45.

4/8/2005
Von Offenberg Sweeney N, Cummins PM, Cotter EJ, Fitzpatrick PA, Birney YA, Redmond EM, Cahill PA. "Cyclic strain-mediated regulation of vascular endothelial cell migration and tube formation." Biochemical and biophysical research communications.. 2005 Apr 8; 329(2):573-82.

3/18/2005
Morrow D, Sweeney C, Birney YA, Cummins PM, Walls D, Redmond EM, Cahill PA. "Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro." Circulation research.. 2005 Mar 18; 96(5):567-75. Epub 2005 Feb 10.

9/1/2004
von Offenberg Sweeney N, Cummins PM, Birney YA, Cullen JP, Redmond EM, Cahill PA. "Cyclic strain-mediated regulation of endothelial matrix metalloproteinase-2 expression and activity." Cardiovascular research.. 2004 Sep 1; 63(4):625-34.

9/2004
Sweeney C, Morrow D, Birney YA, Coyle S, Hennessy C, Scheller A, Cummins PM, Walls D, Redmond EM, Cahill PA. "Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2004 Sep 0; 18(12):1421-3. Epub 2004 Jul 09.

7/2004
von Offenberg Sweeney N; Cummins PM; Birney YA; Redmond EM; Cahill PA. "Cyclic strain-induced endothelial MMP-2: role in vascular smooth muscle cell migration." Biochem Biopys Res Commun. 2004; 320(2): 325-33.

2004
Cullen JP, Nicholl SM, Sayeed S, Sitzmann JV, Okada SS, Cahill PA, Redmond EM. "Plasminogen activator inhibitor-1 deficiency enhances flow-induced smooth muscle cell migration." Thrombosis research.. 2004 114(1):57-65.

2004
Birney YA, Sweeney CH, Cappadona CR, Sitzmann JV, Cummins PM, Redmond EM, Cahill PA. "Pulse pressure-induced transmural fluid flux increases bovine aortic smooth muscle cell apoptosis in a mitogen activated protein kinase dependent manner." Journal of vascular research.. 2004 41(4):364-74. Epub 2004 Sep 06.

10/2003
Birney Y, Redmond EM, Sitzmann JV, Cahill PA. "Eicosanoids in cirrhosis and portal hypertension." Prostaglandins & other lipid mediators. 2003 Oct 0; 72(1-2):3-18.

5/2003
Theodorakis NG, Wang YN, Skill NJ, Metz MA, Cahill PA, Redmond EM, Sitzmann JV. "The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: studies in gene-knockout mice." Gastroenterology.. 2003 May 0; 124(5):1500-8.

10/1/2002
Cullen JP, Sayeed S, Sawai RS, Theodorakis NG, Cahill PA, Sitzmann JV, Redmond EM. "Pulsatile flow-induced angiogenesis: role of G(i) subunits." Arteriosclerosis, thrombosis, and vascular biology.. 2002 Oct 1; 22(10):1610-6.

6/12/2002
Sayeed S, Cullen JP, Coppage M, Sitzmann JV, Redmond EM. "Ethanol differentially modulates the expression and activity of cell cycle regulatory proteins in rat aortic smooth muscle cells." European journal of pharmacology.. 2002 Jun 12; 445(3):163-70.

3/2001
Cahill PA, Redmond EM, Sitzmann JV. "Endothelial dysfunction in cirrhosis and portal hypertension." Pharmacology & therapeutics.. 2001 Mar 0; 89(3):273-93.

1/30/2001
Redmond EM, Cullen JP, Cahill PA, Sitzmann JV, Stefansson S, Lawrence DA, Okada SS. "Endothelial cells inhibit flow-induced smooth muscle cell migration: role of plasminogen activator inhibitor-1." Circulation.. 2001 Jan 30; 103(4):597-603.

5/2000
Redmond EM, Sitzmann JV, Cahill PA. "Potential mechanisms for cardiovascular protective effect of ethanol." Acta pharmacologica Sinica.. 2000 May 0; 21(5):385-90.

7/10/1999
Cappadona C, Redmond EM, Theodorakis NG, McKillop IH, Hendrickson R, Chhabra A, Sitzmann JV, Cahill PA. "Phenotype dictates the growth response of vascular smooth muscle cells to pulse pressure in vitro." Experimental cell research.. 1999 Jul 10; 250(1):174-86.

6/1/1999
Hendrickson RJ, Okada SS, Cahill PA, Yankah E, Sitzmann JV, Redmond EM. "Ethanol inhibits basal and flow-induced vascular smooth muscle cell migration in vitro." The Journal of surgical research.. 1999 Jun 1; 84(1):64-70.

6/1999
Hendrickson RJ, Cahill PA, Sitzmann JV, Redmond EM. "Ethanol enhances basal and flow-stimulated nitric oxide synthase activity in vitro by activating an inhibitory guanine nucleotide binding protein." The Journal of pharmacology and experimental therapeutics.. 1999 Jun 0; 289(3):1293-300.

3/1999
Hendrickson RJ, Cappadona C, Yankah EN, Sitzmann JV, Cahill PA, Redmond EM. "Sustained pulsatile flow regulates endothelial nitric oxide synthase and cyclooxygenase expression in co-cultured vascular endothelial and smooth muscle cells." Journal of molecular and cellular cardiology.. 1999 Mar 0; 31(3):619-29.

2/1999
Redmond EM, Cahill PA, Hirsch M, Wang YN, Sitzmann JV, Okada SS. "Effect of pulse pressure on vascular smooth muscle cell migration: the role of urokinase and matrix metalloproteinase." Thrombosis and haemostasis.. 1999 Feb 0; 81(2):293-300.

12/1998
Hendrickson RJ; Cahill PA; McKillop IH; Sitzmann JV; Redmond EM. "Ethanol inhibits mitogen activated protein kinase activity and growth of vascular smooth muscle cells in vitro." Eur J Parmacol. 1998; 362(2-3): 251-9.

12/1998
Kouretas PC, Hannan RL, Kapur NK, Hendrickson R, Redmond EM, Myers AK, Kim YD, Cahill PA, Sitzmann JV. "Non-anticoagulant heparin increases endothelial nitric oxide synthase activity: role of inhibitory guanine nucleotide proteins." Journal of molecular and cellular cardiology.. 1998 Dec 0; 30(12):2669-82.

11/1998
Mebazaa A, Wetzel RC, Dodd-o JM, Redmond EM, Shah AM, Maeda K, Maistre G, Lakatta EG, Robotham JL. "Potential paracrine role of the pericardium in the regulation of cardiac function." Cardiovascular research.. 1998 Nov 0; 40(2):332-42.

8/1998
Cahill PA, Hou MC, Hendrickson R, Wang YN, Zhang S, Redmond EM, Sitzman JV. "Increased expression of endothelin receptors in the vasculature of portal hypertensive rats: role in splanchnic hemodynamics." Hepatology : official journal of the American Association for the Study of Liver Diseases.. 1998 Aug 0; 28(2):396-403.

1/1998
Hou MC, Cahill PA, Zhang S, Wang YN, Hendrickson RJ, Redmond EM, Sitzmann JV. "Enhanced cyclooxygenase-1 expression within the superior mesenteric artery of portal hypertensive rats: role in the hyperdynamic circulation." Hepatology : official journal of the American Association for the Study of Liver Diseases.. 1998 Jan 0; 27(1):20-7.

1/1998
Redmond EM, Cahill PA, Sitzmann JV. "Flow-mediated regulation of G-protein expression in cocultured vascular smooth muscle and endothelial cells." Arteriosclerosis, thrombosis, and vascular biology.. 1998 Jan 0; 18(1):75-83.

7/1997
Hou MC, Cahill PA, Zhang S, Redmond EM, Sitzmann JV. "Enhanced G-protein-induced relaxation in portal hypertensive rats: role of nitric oxide." Hepatology : official journal of the American Association for the Study of Liver Diseases.. 1997 Jul 0; 26(1):27-33.

1997
Redmond EM, Cahill PA, Sitzmann JV. "Flow-mediated regulation of endothelin receptors in cocultured vascular smooth muscle cells: an endothelium-dependent effect." Journal of vascular research.. 1997 34(6):425-35.

9/1996
Cahill PA, Redmond EM, Hodges R, Zhang S, Sitzmann JV. "Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats." Journal of hepatology.. 1996 Sep 0; 25(3):370-8.

3/1996
Redmond EM, Cahill PA, Hodges R, Zhang S, Sitzmann JV. "Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells." Journal of cellular physiology.. 1996 Mar 0; 166(3):469-79.

2/1996
Cahill PA, Redmond EM, Wu Y, Sitzmann JV. "Regulation of atrial natriuretic factor receptors in portal hypertensive rabbits." Journal of hepatology.. 1996 Feb 0; 24(2):185-93.

9/1995
Redmond EM, Cahill PA, Sitzmann JV. "Perfused transcapillary smooth muscle and endothelial cell co-culture--a novel in vitro model." In vitro cellular & developmental biology. Animal.. 1995 Sep 0; 31(8):601-9.

8/1995
Cahill PA, Foster C, Redmond EM, Gingalewski C, Wu Y, Sitzmann JV. "Enhanced nitric oxide synthase activity in portal hypertensive rabbits." Hepatology : official journal of the American Association for the Study of Liver Diseases.. 1995 Aug 0; 22(2):598-606.

1/16/1995
Cahill PA, Redmond EM, Foster C, Sitzmann JV. "Nitric oxide regulates angiotensin II receptors in vascular smooth muscle cells." European journal of pharmacology.. 1995 Jan 16; 288(2):219-29.

11/1994
Redmond EM, Cherian MN, Wetzel RC. "17 beta-Estradiol inhibits flow- and acute hypoxia-induced prostacyclin release from perfused endocardial endothelial cells." Circulation.. 1994 Nov 0; 90(5):2519-24.

1992
Kent A, Redmond EM, Keenan AK. "The ANF-C receptor is not linked to adenylyl cyclase inhibition in bovine pulmonary artery endothelial cells." Life sciences.. 1992 51(18):1439-44.

12/1990
Cahill PA; Redmond EM; Keenan AK. "Vascular atrial natriuretic factor receptor subtypes are not independently regulated by atrial peptides." J Biol Chem. 1990; 265(35): 1896-906.

8/1990
Redmond EM; Cahill PA; Keenan AK. "Atrial natriuretic factor recognizes two receptor subtypes in endothelial cells cultured from bovine pulmonary artery." FEBS Lett. 1990; 269(1): 157-162.

Books & Chapters

2016
Chapter Title: Common Pathways in Cancer, Angiogenesis and Vascular Disease.
Book Title: Molecular Mechanisms In Cardiac Complications Of Cancer Therapy
Author List: Redmond EM, Lally C, Cahill PA.
Edited By: Roberta Gottleib and Puja Mehta
Published By: Elsevier Ltd2016

2012
Chapter Title: Hemodynamic control of vascular smooth muscle cell function.
Book Title: Vascular Smooth Muscle: Fundamental Biology and Mechanisms of Disease
Author List: Redmond EM , Lally T, Cahill PA.
Edited By: Hill and Olsen
Published By: Elsevier2012

2002
Chapter Title: Alcohol, Vascular Cells and Hemodynamic Forces
Book Title: Alcohol and Heart Disease
Author List: Redmond EM and Cahill PA
Edited By: RR Watson and AK Myers
Published By: Taylor and Francis2002 in London