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Paul G. Rothberg, Ph.D.

Pathology

Contact Information

Phone Numbers

Appointment: (585) 350-2600

Fax: (585) 273-5120

Office: (585) 273-2229

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Biography

Dr. Rothberg is Director of the Molecular Diagnostics Section of the Strong Health clinical laboratories. The Molecular Diagnostics Section uses the techniques of molecular biology to aid in the diagnosis of human disease. Dr. Rothberg is responsible for the planning and development of laboratory tests that support the care of patients with inherited disease, cancer and infectious disease. His research interests include the development of new testing strategies for the measurement of minimal residual disease in cancer patients, and the development of methods to predict response to therapy.

Research

Dr. Rothberg's research focuses on deciphering the role of human genetic variation in the development of disease. Particular areas of focus include cancer and neurodegeneration. Current areas of investigation include studies on the molecular genetics of neuronal ceroid lipofuscinosis (Batten disease) in collaboration with the Batten Disease Clinical and Research Center, the early prediction of drug resistance in chronic myeloid leukemia, and the role of germline variation in the prognosis of prostate cancer.

Credentials

Faculty Appointments

Specialties

  • Clinical Molecular Genetics - American Board of Pathology

Education

1976
BA | Cuny Queens College
Chemistry

1981
PhD | St Univ at Stony Brook
Molecular Biology

Post-doctoral Training & Residency

03/01/1982 - 08/31/1985
Fellowship in at Fox Chase Cancer Center

Publications

Journal Articles

9/2016
Wang X, Stolla M, Ring BZ, Yang Q, Laughlin TS, Rothberg PG, Skinner K, G Hicks D. "p53 alteration in morphologically normal/benign breast tissue in patients with triple-negative high-grade breast carcinomas: breast p53 signature?" Human pathology.. 2016 Sep 0; 55:196-201. Epub 2016 May 28.

9/2016
Joseph L, Cankovic M, Caughron S, Chandra P, Emmadi R, Hagenkord J, Hallam S, Jewell KE, Klein RD, Pratt VM, Rothberg PG, Temple-Smolkin RL, Lyon E. "The Spectrum of Clinical Utilities in Molecular Pathology Testing Procedures for Inherited Conditions and Cancer: A Report of the Association for Molecular Pathology." The Journal of molecular diagnostics : JMD.. 2016 Sep 0; 18(5):605-19. Epub 2016 Aug 16.

6/18/2015
Evans AG, Rothberg PG, Burack WR, Huntington SF, Porter DL, Friedberg JW, Liesveld JL. "Evolution to plasmablastic lymphoma evades CD19-directed chimeric antigen receptor T cells." British journal of haematology.. 2015 Jun 18; Epub 2015 Jun 18.

Books & Chapters

1997
Chapter Title: Use of DNA plymorphisms to monitor engraftment after allogeneic bone marrow transplantation
Book Title: Clinics in Laboratory Medicine 17
Author List: Rothberg, P.G., Gamis, A.S., Baker, D.
Published By: W. B. Saunders1997

1995
Chapter Title: Adventures in MYC-ology
Book Title: Advances in Genome Biology
Author List: Rothberg, P.G.; Heruth, D.P.
Edited By: Ram S. Verma
Published By: JAI Press Inc1995

1989
Chapter Title: Amplification and activation of the c-myc oncogene in adenocarcinoma of the large bowel.
Book Title: Familial Adenomatous Polyposis
Author List: Herold, K.M.; Rothberg, P.G
Published By: Alan R. Liss, Inc1989

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