Research Bio
Infection with respiratory syncytial virus (RSV) can cause severe respiratory diseases in infants. My research goal is identify the genetic mechanisms of susceptibility to RSV infection. My current research focuses on discovering the genomic alterations within the immune system of the infants with RSV infection by analyzing the patients' data obtained from high throughput sequencing, particularly RNA-Seq. I am also interested in algorithm discovery and development for next generating sequencing data analysis.
2016
*Chu, CY.; *Qiu, X.; Wang, L.; Bhattacharya, S.; Lofthus, G.; Corbett, A.; Holden-Wiltse, J.; Grier, A,; Tesini, B.; Gill, S.; Falsey, A.; Caserta, M.; Walsh, E.; Mariani, T. "The Healthy Infant Nasal Transcriptome: A Benchmark Study". Scientific Reports. 2016; . |
2015 Aug
Chuang KH, Whitney-Miller CL, Chu CY, Zhou Z, Dokus MK, Schmit S, Barry CT. "MicroRNA-494 is a master epigenetic regulator of multiple invasion-suppressor microRNAs by targeting ten eleven translocation 1 in invasive human hepatocellular carcinoma tumors." Hepatology : official journal of the American Association for the Study of Liver Diseases. 2015 Aug; 62(2):466-80. Epub 2015 May 06. |
2014 Oct 1
Bhattacharya S, Zhou Z, Yee M, Chu CY, Lopez AM, Lunger VA, Solleti SK, Resseguie E, Buczynski BW, Mariani TJ, O'Reilly MA. "The genome-wide transcriptional response to neonatal hyperoxia identifies Ahr as a key regulator." American journal of physiology. Lung cellular and molecular physiology. 2014 Oct 1; 307(7):L516-23. Epub 2014 Aug 22. |
2009 May 11
Chuang KH, Altuwaijri S, Li G, Lai JJ, Chu CY, Lai KP, Lin HY, Hsu JW, Keng P, Wu MC, Chang C. "Neutropenia with impaired host defense against microbial infection in mice lacking androgen receptor." The Journal of experimental medicine. 2009 May 11; 206(5):1181-99. Epub 2009 May 04. |
2007 Jul
Viale A, Li J, Tiesman J, Hester S, Massimi A, Griffin C, Grills G, Khitrov G, Lilley K, Knudtson K, Ward B, Kornacker K, Chu CY, Auer H, Brooks AI. "Big results from small samples: evaluation of amplification protocols for gene expression profiling." Journal of biomolecular techniques : JBT. 2007 Jul; 18(3):150-61. |
