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Arshad Rahman, Ph.D.

Publications

Showing all 60 journal articles & 3 books available

Journal Articles

10/26/2017
Slavin SA, Leonard A, Grose V, Fazal F, Rahman A. "Autophagy Inhibitor 3-Methyladenine Protects against Endothelial Cell Barrier Dysfunction in Acute Lung Injury." American journal of physiology. Lung cellular and molecular physiology.. 2017 Oct 26; :ajplung.00555.2016. Epub 2017 Oct 26.

11/2016
Angara S, Syed M, Das P, Janér C, Pryhuber G, Rahman A, Andersson S, Homer RJ, Bhandari V. "Inhibition of Regulatory-Associated Protein of Mechanistic Target of Rapamycin Prevents Hyperoxia-Induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice." American journal of respiratory cell and molecular biology.. 2016 Nov 0; 55(5):722-735.

8/1/2016
Bijli KM, Fazal F, Slavin SA, Leonard A, Grose V, Alexander WB, Smrcka AV, Rahman A. "Phospholipase C-? signaling mediates endothelial cell inflammation and barrier disruption in acute lung injury." American journal of physiology. Lung cellular and molecular physiology.. 2016 Aug 1; 311(2):L517-24. Epub 2016 Jul 01.

8/1/2015
Solleti SK, Simon DM, Srisuma S, Arikan MC, Bhattacharya S, Rangasamy T, Bijli KM, Rahman A, Crossno JT, Shapiro SD, Mariani TJ. "Airway epithelial cell PPAR? modulates cigarette smoke-induced chemokine expression and emphysema susceptibility in mice." American journal of physiology. Lung cellular and molecular physiology.. 2015 Aug 1; 309(3):L293-304. Epub 2015 May 29.

12/2014
Bijli KM, Kanter BG, Minhajuddin M, Leonard A, Xu L, Fazal F, Rahman A. "Regulation of endothelial cell inflammation and lung polymorphonuclear lymphocyte infiltration by transglutaminase 2." Shock.. 2014 Dec 0; 42(6):562-9.

2013
Leonard A, Marando C, Rahman A, Fazal F. "Thrombin selectively engages LIM kinase1 and slingshot-1L phosphatase to regulate NF-?B activation and endothelial cell inflammation." Am J Physiol: Lung Cell Mol Physiol. 2013; 305: L651-64.

2013
Fazal F, Bijli KM, Murrill M, Leonard A, Minhajuddin M, Anwar KN, Finkelstein JN, Watterson DM, Rahman A. "Critical role of non-muscle myosin light chain kinase in thrombin-induced endothelial cell inflammation and lung PMN infiltration." PloS one. 2013 8(3):e59965. Epub 2013 Mar 21.

11/2012
Bijli KM, Fazal F, Rahman A. "Regulation of Rela/p65 and endothelial cell inflammation by proline-rich tyrosine kinase 2." American journal of respiratory cell and molecular biology.. 2012 Nov 0; 47(5):660-8. Epub 2012 Jul 27.

8/15/2011
Yang L, Chen G, Mohanty S, Scott G, Fazal F, Rahman A, Begum S, Hynes R, Xu L. "GPR56 Regulates VEGF production and angiogenesis during melanoma progression." Cancer research.. 2011 Aug 15; 71(16):5558-68. Epub 2011 Jul 01.

7/31/2009
Fazal F, Bijli KM, Minhajuddin M, Rein T, Finkelstein JN, Rahman A. "Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells." The Journal of biological chemistry.. 2009 Jul 31; 284(31):21047-56. Epub 2009 May 29.

2/13/2009
Minhajuddin M, Bijli KM, Fazal F, Sassano A, Nakayama KI, Hay N, Platanias LC, Rahman A. "Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells." The Journal of biological chemistry.. 2009 Feb 13; 284(7):4052-61. Epub 2008 Dec 13.

7/2008
Edirisinghe I, Yang SR, Yao H, Rajendrasozhan S, Caito S, Adenuga D, Wong C, Rahman A, Phipps RP, Jin ZG, Rahman I. "VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2008 Jul 0; 22(7):2297-310. Epub 2008 Feb 08.

5/23/2008
Bijli KM, Fazal F, Minhajuddin M, Rahman A. "Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65." The Journal of biological chemistry.. 2008 May 23; 283(21):14674-84. Epub 2008 Mar 24.

2/9/2007
Fazal F, Minhajuddin M, Bijli KM, McGrath JL, Rahman A. "Evidence for actin cytoskeleton-dependent and -independent pathways for RelA/p65 nuclear translocation in endothelial cells." The Journal of biological chemistry.. 2007 Feb 9; 282(6):3940-50. Epub 2006 Dec 08.

2/2007
Bijli KM, Minhajuddin M, Fazal F, O'Reilly MA, Platanias LC, Rahman A. "c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells." American journal of physiology. Lung cellular and molecular physiology.. 2007 Feb 0; 292(2):L396-404. Epub 2006 Sep 29.

2007
Garin G, Abe J, Mohan A, Lu W, Yan C, Newby AC, Rhaman A, Berk BC. "Berk BC. Flow antagonizes TNF? signaling in endothelial cells by inhibiting caspase-dependent PKC zeta processing." Circ Res. 2007; 101(1): 97-105.

10/2006
Orrington-Myers J, Gao X, Kouklis P, Broman M, Rahman A, Vogel SM, Malik AB. "Regulation of lung neutrophil recruitment by VE-cadherin." American journal of physiology. Lung cellular and molecular physiology.. 2006 Oct 0; 291(4):L764-71. Epub 2006 Jun 16.

8/15/2006
Staversky RJ, Vitiello PF, Gehen SC, Helt CE, Rahman A, Keng PC, O'Reilly MA. "p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L)." Free radical biology & medicine.. 2006 Aug 15; 41(4):601-9. Epub 2006 May 23.

6/9/2006
Frey RS, Gao X, Javaid K, Siddiqui SS, Rahman A, Malik AB. "Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells." The Journal of biological chemistry.. 2006 Jun 9; 281(23):16128-38. Epub 2006 Mar 09.

5/1/2005
Minhajuddin M, Fazal F, Bijli KM, Amin MR, Rahman A. "Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells." The Journal of immunology : official journal of the American Association of Immunologists.. 2005 May 1; 174(9):5823-9.

12/1/2004
Anwar KN, Fazal F, Malik AB, Rahman A. "RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65." The Journal of immunology : official journal of the American Association of Immunologists.. 2004 Dec 1; 173(11):6965-72.

11/2004
Rahman A, Anwar KN, Minhajuddin M, Bijli KM, Javaid K, True AL, Malik AB. "cAMP targeting of p38 MAP kinase inhibits thrombin-induced NF-kappaB activation and ICAM-1 expression in endothelial cells." American journal of physiology. Lung cellular and molecular physiology.. 2004 Nov 0; 287(5):L1017-24. Epub 2004 Jul 09.

10/2003
Ong ES, Gao XP, Xu N, Predescu D, Rahman A, Broman MT, Jho DH, Malik AB. "E. coli pneumonia induces CD18-independent airway neutrophil migration in the absence of increased lung vascular permeability." American journal of physiology. Lung cellular and molecular physiology.. 2003 Oct 0; 285(4):L879-88. Epub 2003 Jun 20.

9/26/2003
Paria BC, Malik AB, Kwiatek AM, Rahman A, May MJ, Ghosh S, Tiruppathi C. "Tumor necrosis factor-alpha induces nuclear factor-kappaB-dependent TRPC1 expression in endothelial cells." The Journal of biological chemistry.. 2003 Sep 26; 278(39):37195-203. Epub 2003 Jul 10.

8/29/2003
Kambhampati S, Li Y, Verma A, Sassano A, Majchrzak B, Deb DK, Parmar S, Giafis N, Kalvakolanu DV, Rahman A, Uddin S, Minucci S, Tallman MS, Fish EN, Platanias LC. "Activation of protein kinase C delta by all-trans-retinoic acid." The Journal of biological chemistry.. 2003 Aug 29; 278(35):32544-51. Epub 2003 Jun 12.

7/1/2003
Deb DK, Sassano A, Lekmine F, Majchrzak B, Verma A, Kambhampati S, Uddin S, Rahman A, Fish EN, Platanias LC. "Activation of protein kinase C delta by IFN-gamma." The Journal of immunology : official journal of the American Association of Immunologists.. 2003 Jul 1; 171(1):267-73.

5/30/2003
Javaid K, Rahman A, Anwar KN, Frey RS, Minshall RD, Malik AB. "Tumor necrosis factor-alpha induces early-onset endothelial adhesivity by protein kinase Czeta-dependent activation of intercellular adhesion molecule-1." Circulation research.. 2003 May 30; 92(10):1089-97. Epub 2003 Apr 24.

2003
Babcock TA, Kurland A, Helton WS, Rahman A, Anwar KN, Espat NJ. "Inhibition of activator protein-1 transcription factor activation by omega-3 fatty acid modulation of mitogen-activated protein kinase signaling kinases." JPEN. Journal of parenteral and enteral nutrition.. 2003 27(3):176-80; discussion 181.

9/6/2002
Rahman A, True AL, Anwar KN, Ye RD, Voyno-Yasenetskaya TA, Malik AB. "Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells." Circulation research.. 2002 Sep 6; 91(5):398-405.

8/15/2002
Skidgel RA, Gao XP, Brovkovych V, Rahman A, Jho D, Predescu S, Standiford TJ, Malik AB. "Nitric oxide stimulates macrophage inflammatory protein-2 expression in sepsis." The Journal of immunology : official journal of the American Association of Immunologists.. 2002 Aug 15; 169(4):2093-101.

5/17/2002
Frey RS, Rahman A, Kefer JC, Minshall RD, Malik AB. "PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells." Circulation research.. 2002 May 17; 90(9):1012-9.

4/26/2002
Uddin S, Sassano A, Deb DK, Verma A, Majchrzak B, Rahman A, Malik AB, Fish EN, Platanias LC. "Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727." The Journal of biological chemistry.. 2002 Apr 26; 277(17):14408-16. Epub 2002 Feb 11.

4/15/2002
Gao XP, Standiford TJ, Rahman A, Newstead M, Holland SM, Dinauer MC, Liu QH, Malik AB. "Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice." The Journal of immunology : official journal of the American Association of Immunologists.. 2002 Apr 15; 168(8):3974-82.

4/2002
Xu N, Gao XP, Minshall RD, Rahman A, Malik AB. "Time-dependent reversal of sepsis-induced PMN uptake and lung vascular injury by expression of CD18 antagonist." American journal of physiology. Lung cellular and molecular physiology.. 2002 Apr 0; 282(4):L796-802.

2/1/2002
Fan J, Frey RS, Rahman A, Malik AB. "Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-alpha -induced NF-kappa B activation and intercellular adhesion molecule-1 expression in endothelial cells." The Journal of biological chemistry.. 2002 Feb 1; 277(5):3404-11. Epub 2001 Nov 29.

9/1/2001
Gao X, Xu N, Sekosan M, Mehta D, Ma SY, Rahman A, Malik AB. "Differential role of CD18 integrins in mediating lung neutrophil sequestration and increased microvascular permeability induced by Escherichia coli in mice." The Journal of immunology : official journal of the American Association of Immunologists.. 2001 Sep 1; 167(5):2895-901.

8/2001
Rahman A, Anwar KN, Uddin S, Xu N, Ye RD, Platanias LC, Malik AB. "Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase." Molecular and cellular biology.. 2001 Aug 0; 21(16):5554-65.

6/22/2001
Mehta D, Rahman A, Malik AB. "Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function." The Journal of biological chemistry.. 2001 Jun 22; 276(25):22614-20. Epub 2001 Apr 17.

6/1/2001
Yang M, Sang H, Rahman A, Wu D, Malik AB, Ye RD. "G alpha 16 couples chemoattractant receptors to NF-kappa B activation." The Journal of immunology : official journal of the American Association of Immunologists.. 2001 Jun 1; 166(11):6885-92.

1/2001
Kefer J, Rahman A, Anwar KN, Malik AB. "Decreased oxidant buffering impairs NF-kappaB activation and ICAM-1 transcription in endothelial cells." Shock.. 2001 Jan 0; 15(1):11-5.

10/2000
Rahman A, Anwar KN, Malik AB. "Protein kinase C-zeta mediates TNF-alpha-induced ICAM-1 gene transcription in endothelial cells." American journal of physiology. Cell physiology.. 2000 Oct 0; 279(4):C906-14.

8/4/2000
Xu N, Rahman A, Minshall RD, Tiruppathi C, Malik AB. "beta(2)-Integrin blockade driven by E-selectin promoter prevents neutrophil sequestration and lung injury in mice." Circulation research.. 2000 Aug 4; 87(3):254-60.

2000
True, A.L., Rahman, A., Malik, A.B. "Activation of NF-kB induced by H2O2 and TNFa in endothelial cells and effect on ICAM-1 expression." Am. J. Physiol: Lung Mol. Cell. Physiolol. 2000; 279: L302-L311.

11/1999
Lo SK, Rahman A, Xu N, Zhou MY, Nagpala P, Jaffe HA, Malik AB. "Neutrophil inhibitory factor abrogates neutrophil adhesion by blockade of CD11a and CD11b beta(2) integrins." Molecular pharmacology.. 1999 Nov 0; 56(5):926-32.

5/1/1999
Rahman A, Anwar KN, True AL, Malik AB. "Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion." The Journal of immunology : official journal of the American Association of Immunologists.. 1999 May 1; 162(9):5466-76.

3/1999
Rahman A, Bando M, Kefer J, Anwar KN, Malik AB. "Protein kinase C-activated oxidant generation in endothelial cells signals intercellular adhesion molecule-1 gene transcription." Molecular pharmacology.. 1999 Mar 0; 55(3):575-83.

1998
Rahman, A., Kefer, J., Bando, M., Niles, W.D., Malik, A.B. "E-selectin expression in human endothelial cells by TNFa-induced oxidant generation and NF-kB activation." Am. J. Physiol. 1998; 19: L533-L544.

8/11/1995
Roebuck KA, Rahman A, Lakshminarayanan V, Janakidevi K, Malik AB. "H2O2 and tumor necrosis factor-alpha activate intercellular adhesion molecule 1 (ICAM-1) gene transcription through distinct cis-regulatory elements within the ICAM-1 promoter." The Journal of biological chemistry.. 1995 Aug 11; 270(32):18966-74.

7/1995
Rahman A, Malhotra P, Dhar R, Kewalramani T, Thimmapaya B. "Effect of single-base substitutions in the central domain of virus-associated RNA I on its function." Journal of virology.. 1995 Jul 0; 69(7):4299-307.

1994
Fazal, F., Rahman, A., Hadi, S.M. "Generation of superoxide anion and hydroxyl radical by methylglyoxal." Med. Sci. Res. 1994; 22: 21-24.

4/1992
Said Ahmad M, Fazal F, Rahman A, Hadi SM, Parish JH. "Activities of flavonoids for the cleavage of DNA in the presence of Cu(II): correlation with generation of active oxygen species." Carcinogenesis.. 1992 Apr 0; 13(4):605-8.

4/1992
Rahman A, Fazal F, Greensill J, Ainley K, Parish JH, Hadi SM. "Strand scission in DNA induced by dietary flavonoids: role of Cu(I) and oxygen free radicals and biological consequences of scission." Molecular and cellular biochemistry.. 1992 Apr 0; 111(1-2):3-9.

10/1991
Shahabuddin , Rahman A, Hadi SM. "Reaction of furfural and methylfurfural with DNA: use of single-strand-specific nucleases." Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.. 1991 Oct 0; 29(10):719-21.

11/1990
Fazal F, Rahman A, Greensill J, Ainley K, Hadi SM, Parish JH. "Strand scission in DNA by quercetin and Cu(II): identification of free radical intermediates and biological consequences of scission." Carcinogenesis.. 1990 Nov 0; 11(11):2005-8.

11/1990
Rahman A, Shahabuddin , Hadi SM, Parish JH. "Complexes involving quercetin, DNA and Cu(II)." Carcinogenesis.. 1990 Nov 0; 11(11):2001-3.

3/1990
Shahabuddin , Rahman A, Hadi SM. "Specificity of the in vitro interaction of methylfurfural with DNA." Mutagenesis.. 1990 Mar 0; 5(2):131-6.

1990
Rahman A, Shahabuddin , Hadi SM. "Formation of strand breaks and interstrand cross-links in DNA by methylglyoxal." Journal of biochemical toxicology.. 1990 5(3):161-6.

10/1989
Rahman A, Shahabuddin , Hadi SM, Parish JH, Ainley K. "Strand scission in DNA induced by quercetin and Cu(II): role of Cu(I) and oxygen free radicals." Carcinogenesis.. 1989 Oct 0; 10(10):1833-9.

3/1989
Hadi SM, Shahabuddin , Rehman A. "Specificity of the interaction of furfural with DNA." Mutation research.. 1989 Mar 0; 225(3):101-6.

1986
Rizvi, R.Y., Uddin, S., Rahman, A., Hadi, S. M. "Effect of alkylation with streptozotocin on the secondary structure of DNA." Biosc. Rep. 1986; 6: 557-564.

Books & Chapters

2007
Chapter Title: Nuclear Factor-kappaB Signaling in Endothelium
Book Title: Endothelial Biomedicine
Author List: Bijli KM, Rahman A
Edited By: Aird WC
Published By: Cambridge University Press2007

1996
Chapter Title: Transcriptional regulation of endothelial adhesion molecule gene expression by oxidants and cytokines.
Book Title: Nitric Oxide and Radicals in the Pulmonary Vasculature. Proceedings of the VII
Author List: Rahman A, Roebuck KA, Malik AB
Edited By: Weir EK, Archer SL, Reeves JT
Published By: Futura Publishing Co.1996 in New York, NY

1993
Chapter Title: Strand scission in DNA induced by dietary flavonoids: role of Cu(I) and oxygen free radicals.
Book Title: Glimpses in Plant Research XI: Medicinal Plants; New Vistas of Research-Part 2
Author List: Rahman A, Fazal F, Hadi SM
Edited By: Govil JN, Singh VK, Hashmi S
Published By: Today and Tomorrow's Printers and Publishers1993 in New Delhi, India