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Paul Spencer Brookes, Ph.D.

Contact Information

Phone Numbers

Appointment: (585) 276-3000

Research Labs

Faculty Appointments

Credentials

Education

1993
BS | UK - Non-Medical School
Biochemistry

1997
PhD | UK-Cambridge U Med Sch
Biochemistry

Awards

2006 - 2006
Anthony Linnane Award for outstanding contribution to mitochondrial research
Sponsor: United Mitochondrial Disease Foundation

1999
Young Investigator Award
Sponsor: 6th Annual Meeting, Society for Free Radical Biology & Medicine

Patents

Patent Title: Mitochondria-Targeted Anitoxidant Prodrugs and Methods of Use
Patent #: 8,470,861
Issue Date: Jun 25, 2013
Country: United States
Invented By: Marion W Anders, Paul S Brookes, Leif Olson, Richard L Parton, James L Robotham, Shey-Shing Sheu, Jalai Shojaie

Publications

Journal Articles

8/2018
Nadtochiy SM, Wang YT, Nehrke K, Munger J, Brookes PS. "Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH." Journal of molecular and cellular cardiology.. 2018 Aug 0; 121:155-162. Epub 2018 Jun 26.

6/4/2018
Smith CO, Wang YT, Nadtochiy SM, Miller JH, Jonas EA, Dirksen RT, Nehrke K, Brookes PS. "Cardiac metabolic effects of K1.2 channel deletion and evidence for its mitochondrial localization." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2018 Jun 4; :fj201800139R. Epub 2018 Jun 04.

5/29/2018
Zhang J, Wang YT, Miller JH, Day MM, Munger JC, Brookes PS. "Accumulation of Succinate in Cardiac Ischemia Primarily Occurs via Canonical Krebs Cycle Activity." Cell reports.. 2018 May 29; 23(9):2617-2628.

Books & Chapters

2008
Chapter Title: The interaction of mitochondrial membranes with reactive oxygen and nitrogen species
Book Title: Free Radical Effects on Membranes
Author List: Brookes PS, Wojtovich AP, Burwell LS, Hoffman DL, Nadtochiy SM
Edited By: S Matalon, S Simon, D Benos
Published By: Elsevier 2008 in NY

2008
Chapter Title: Aging & Cardiac Ischemia: Mitochondrial Free Radical Considerations
Book Title: Oxidative Stress in Aging: From Model Systems to Human Diseases
Author List: Brookes PS, Hoffman DL
Edited By: S Miwa, K Beckman, F Muller
Published By: Springer Verlag 2008 in NY

2006
Chapter Title: Methods for measuring the regulation of respiration by nitric oxide
Book Title: Mitochondria - Methods in Cell Biology Series
Author List: Shiva, S; Brookes, PS; Darley-Usmar, VM
Edited By: Eds. L Pon and Eric Schon
Published By: Press/Elsevier 2006 in San Diego

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