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Paul Spencer Brookes, Ph.D.

Contact Information

Research Labs

Faculty Appointments

Credentials

Education

1993
BS | UK - Non-Medical School
Biochemistry

1997
PhD | UK-Cambridge U Med Sch
Biochemistry

Awards

2006 - 2006
Anthony Linnane Award for outstanding contribution to mitochondrial research
Sponsor: United Mitochondrial Disease Foundation

1999
Young Investigator Award
Sponsor: 6th Annual Meeting, Society for Free Radical Biology & Medicine

Patents

Patent Title: Mitochondria-Targeted Antioxidant Prodrugs and Methods of Use
Patent #: 8,470,861
Issue Date: Jun 25, 2013
Country: United States
Invented By: Marion W Anders, Paul S Brookes, Leif Olson, Richard L Parton, James L Robotham, Shey-Shing Sheu, Jalai Shojaie

Publications

Journal Articles

8/14/2020
Kulkarni CA, Nadtochiy SM, Kennedy L, Zhang J, Chhim S, Alwaseem H, Murphy E, Fu D, Brookes PS. "ALKBH7 mediates necrosis via rewiring of glyoxal metabolism." eLife.. 2020 Aug 14; 9Epub 2020 Aug 14.

7/14/2020
Milliken AS, Brookes PS. "Amber Alert: Getting to the Heart of Succinate Efflux in Reperfusion Injury." Cardiovascular research.. 2020 Jul 14; Epub 2020 Jul 14.

7/13/2020
Bennett JA, Mastrangelo MA, Ture SK, Smith CO, Loelius SG, Berg RA, Shi X, Burke RM, Spinelli SL, Cameron SJ, Carey TE, Brookes PS, Gerszten RE, Sabater-Lleal M, de Vries PS, Huffman JE, Smith NL, Morrell CN, Lowenstein CJ. "The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function." Nature communications.. 2020 Jul 13; 11(1):3479. Epub 2020 Jul 13.

Books & Chapters

2008
Chapter Title: The interaction of mitochondrial membranes with reactive oxygen and nitrogen species
Book Title: Free Radical Effects on Membranes
Author List: Brookes PS, Wojtovich AP, Burwell LS, Hoffman DL, Nadtochiy SM
Edited By: S Matalon, S Simon, D Benos
Published By: Elsevier 2008 in NY

2008
Chapter Title: Aging & Cardiac Ischemia: Mitochondrial Free Radical Considerations
Book Title: Oxidative Stress in Aging: From Model Systems to Human Diseases
Author List: Brookes PS, Hoffman DL
Edited By: S Miwa, K Beckman, F Muller
Published By: Springer Verlag 2008 in NY

2006
Chapter Title: Methods for measuring the regulation of respiration by nitric oxide
Book Title: Mitochondria - Methods in Cell Biology Series
Author List: Shiva, S; Brookes, PS; Darley-Usmar, VM
Edited By: Eds. L Pon and Eric Schon
Published By: Press/Elsevier 2006 in San Diego

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