Publications
Showing all 381 journal articles & 17 books available
Journal Articles
9/4/2023
Holstein-Rønsbo S, Gan Y, Giannetto MJ, Rasmussen MK, Sigurdsson B, Beinlich FRM, Rose L, Untiet V, Hablitz LM, Kelley DH, Nedergaard M. "Publisher Correction: Glymphatic influx and clearance are accelerated by neurovascular coupling." Nature neuroscience.. 2023 Sep 4; Epub 2023 Sep 04.
9/2/2023
Ozawa K, Nagao M, Konno A, Iwai Y, Vittani M, Kusk P, Mishima T, Hirai H, Nedergaard M, Hirase H. "Astrocytic GPCR-Induced Ca Signaling Is Not Causally Related to Local Cerebral Blood Flow Changes." International journal of molecular sciences.. 2023 Sep 2; 24(17)Epub 2023 Sep 02.
9/2023
Gan Y, Holstein-Rønsbo S, Nedergaard M, Boster KAS, Thomas JH, Kelley DH. "Perivascular pumping of cerebrospinal fluid in the brain with a valve mechanism." Journal of the Royal Society, Interface. 2023 Sep; 20(206):20230288. Epub 2023 Sep 20.
8/31/2023
Staudt M, Shalgunov V, Nedergaard M, Herth MM. "Development of C-labeled CRANAD-102 for positron emission tomography imaging of soluble A?-species." Journal of labelled compounds & radiopharmaceuticals.. 2023 Aug 31; Epub 2023 Aug 31.
8/5/2023
Andersen M, Tsopanidou A, Radovanovic T, Compere VN, Hauglund N, Nedergaard M, Kjaerby C. "Using Fiber Photometry in Mice to Estimate Fluorescent Biosensor Levels During Sleep." Bio-protocol.. 2023 Aug 5; 13(15):e4734. Epub 2023 Aug 05.
7/24/2023
Kim D, Gan Y, Nedergaard M, Kelley DH, Tithof J. "Image Analysis Techniques for In Vivo Quantification of Cerebrospinal Fluid Flow." bioRxiv : the preprint server for biology.. 2023 Jul 24; Epub 2023 Jul 24.
7/21/2023
Miyakoshi LM, Stæger FF, Li Q, Pan C, Xie L, Kang H, Pavan C, Dang J, Sun Q, Ertürk A, Nedergaard M. "The state of brain activity modulates cerebrospinal fluid transport." Progress in neurobiology.. 2023 Jul 21; :102512. Epub 2023 Jul 21.
7/17/2023
Raicevic N, Forer JM, Ladrón-de-Guevara A, Du T, Nedergaard M, Kelley DH, Boster K. "Sizes and shapes of perivascular spaces surrounding murine pial arteries." Fluids and barriers of the CNS.. 2023 Jul 17; 20(1):56. Epub 2023 Jul 17.
7/10/2023
Vittani M, Knak PAG, Fukuda M, Nagao M, Wang X, Kjaerby C, Konno A, Hirai H, Nedergaard M, Hirase H. "Virally induced CRISPR/Cas9-based knock-in of fluorescent albumin allows long-term visualization of cerebral circulation in infant and adult mice." bioRxiv : the preprint server for biology.. 2023 Jul 10; Epub 2023 Jul 10.
7/2023
Bork PAR, Ladrón-de-Guevara A, Christensen AH, Jensen KH, Nedergaard M, Bohr T. "Astrocyte endfeet may theoretically act as valves to convert pressure oscillations to glymphatic flow." Journal of the Royal Society, Interface. 2023 Jul; 20(204):20230050. Epub 2023 Jul 12.
6/28/2023
Mathiesen BK, Miyakoshi LM, Cederroth CR, Tserga E, Versteegh C, Bork PAR, Hauglund NL, Gomolka RS, Mori Y, Edvall NK, Rouse S, Møllgård K, Holt JR, Nedergaard M, Canlon B. "Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice." Science translational medicine.. 2023 Jun 28; 15(702):eabq3916. Epub 2023 Jun 28.
6/2023
Holstein-Rønsbo S, Gan Y, Giannetto MJ, Rasmussen MK, Sigurdsson B, Beinlich FRM, Rose L, Untiet V, Hablitz LM, Kelley DH, Nedergaard M. "Glymphatic influx and clearance are accelerated by neurovascular coupling." Nature neuroscience.. 2023 Jun; 26(6):1042-1053. Epub 2023 Jun 01.
5/24/2023
Raizen DM, Mullington J, Anaclet C, Clarke G, Critchley H, Dantzer R, Davis R, Drew KL, Fessel J, Fuller PM, Gibson EM, Harrington M, Lipkin WI, Klerman EB, Klimas N, Komaroff AL, Koroshetz W, Krupp L, Kuppuswamy A, Lasselin J, Lewis LD, Magistretti PJ, Matos HY, Miaskowski C, Miller AH, Nath A, Nedergaard M, Opp MR, Ritchie MD, Rogulja D, Rolls A, Salamone JD, Saper C, Whittemore V, Wylie G, Younger J, Zee PC, Heller HC. "Beyond the Symptom: The Biology of Fatigue." Sleep.. 2023 May 24; Epub 2023 May 24.
5/4/2023
Agarwal N, Lewis LD, Hirschler L, Rivera LR, Naganawa S, Levendovszky SR, Ringstad G, Klarica M, Wardlaw J, Iadecola C, Hawkes C, Carare RO, Wells J, Bakker ENTP, Kurtcuoglu V, Bilston L, Nedergaard M, Mori Y, Stoodley M, Alperin N, de Leon M, van Osch MJP. "Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 "ISMRM Imaging Neurofluids Study group" Workshop in Rome." Journal of magnetic resonance imaging : JMRI.. 2023 May 4; Epub 2023 May 04.
4/20/2023
Kjaerby C, Andersen M, Hauglund N, Untiet V, Dall C, Ding F, Hirase H, Nedergaard M. "Reply to: 'Do all norepinephrine surges disrupt sleep?'." Nature neuroscience.. 2023 Apr 20; Epub 2023 Apr 20.
4/4/2023
Boster KAS, Cai S, Ladrón-de-Guevara A, Sun J, Zheng X, Du T, Thomas JH, Nedergaard M, Karniadakis GE, Kelley DH. "Artificial intelligence velocimetry reveals in vivo flow rates, pressure gradients, and shear stresses in murine perivascular flows." Proceedings of the National Academy of Sciences of the United States of America.. 2023 Apr 4; 120(14):e2217744120. Epub 2023 Mar 29.
4/4/2023
Untiet V, Beinlich FRM, Kusk P, Kang N, Ladrón-de-Guevara A, Song W, Kjaerby C, Andersen M, Hauglund N, Bojarowska Z, Sigurdsson B, Deng S, Hirase H, Petersen NC, Verkhratsky A, Nedergaard M. "Astrocytic chloride is brain state dependent and modulates inhibitory neurotransmission in mice." Nature communications.. 2023 Apr 4; 14(1):1871. Epub 2023 Apr 04.
3/31/2023
Parka A, Volbracht C, Hall B, Bastlund JF, Nedergaard M, Laursen B, Botta P, Sotty F. "Visual Evoked Potentials as an Early-Stage Biomarker in the rTg4510 Tauopathy Mouse Model." Journal of Alzheimer's disease : JAD.. 2023 Mar 31; Epub 2023 Mar 31.
3/30/2023
Ge GR, Rolland JP, Song W, Nedergaard M, Parker KJ. "Fluid compartments influence elastography of the aging mouse brain." Physics in medicine and biology.. 2023 Mar 30; Epub 2023 Mar 30.
3/22/2023
Shalgunov V, Lopes van den Broek S, Vang Andersen I, García Vázquez R, Raval NR, Palner M, Mori Y, Schäfer G, Herrmann B, Mikula H, Beschorner N, Nedergaard M, Syvänen S, Barz M, Moos Knudsen G, Battisti UM, Herth MM. "Pretargeted imaging beyond the blood-brain barrier." RSC medicinal chemistry.. 2023 Mar 22; 14(3):444-453. Epub 2022 Dec 02.
3/13/2023
Delle C, Cankar N, Digebjerg Holgersson C, Hvorup Knudsen H, Schiøler Nielsen E, Kjaerby C, Mori Y, Nedergaard M, Weikop P. "Long-term high-fat diet increases glymphatic activity in the hypothalamus in mice." Scientific reports.. 2023 Mar 13; 13(1):4137. Epub 2023 Mar 13.
2/21/2023
Sigurdsson B, Hauglund NL, Lilius TO, Mogensen FL, Mortensen KN, Beschorner N, Klinger L, Bærentzen SL, Rosenholm MP, Shalgunov V, Herth M, Mori Y, Nedergaard M. "A SPECT-based method for dynamic imaging of the glymphatic system in rats." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2023 Feb 21; :271678X231156982. Epub 2023 Feb 21.
2/17/2023
Raicevic N, Forer JM, Ladron-de-Guevara A, Du T, Nedergaard M, Kelley DH, Boster KAS. "Sizes and Shapes of Perivascular Spaces Surrounding Murine Pial Arteries." Research square.. 2023 Feb 17; Epub 2023 Feb 17.
2/9/2023
Gomolka RS, Hablitz LM, Mestre H, Giannetto M, Du T, Hauglund NL, Xie L, Peng W, Martinez PM, Nedergaard M, Mori Y. "Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation." eLife.. 2023 Feb 9; 12Epub 2023 Feb 09.
1/30/2023
Lilius TO, Mortensen KN, Deville C, Lohela TJ, Stæger FF, Sigurdsson B, Fiordaliso EM, Rosenholm M, Kamphuis C, Beekman FJ, Jensen AI, Nedergaard M. "Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles." Journal of controlled release : official journal of the Controlled Release Society.. 2023 Jan 30; Epub 2023 Jan 30.
1/23/2023
Parka A, Degel C, Dreyer J, Richter U, Hall B, Bastlund JF, Laursen B, Nedergaard M, Sotty F, Botta P. "Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model." Neurobiology of disease.. 2023 Jan 23; 178:106012. Epub 2023 Jan 23.
1/6/2023
Møllgård K, Beinlich FRM, Kusk P, Miyakoshi LM, Delle C, Plá V, Hauglund NL, Esmail T, Rasmussen MK, Gomolka RS, Mori Y, Nedergaard M. "A mesothelium divides the subarachnoid space into functional compartments." Science.. 2023 Jan 6; 379(6627):84-88. Epub 2023 Jan 05.
2023
Hirase H, Nedergaard M. "Locomotion Induces Fundamentally Different Patterns of Ca Signaling in Astrocytes and Neurons." Function.. 2023 4(4):zqad028. Epub 2023 Jun 05.
12/15/2022
Liu G, Ladrón-de-Guevara A, Izhiman Y, Nedergaard M, Du T. "Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies." Fluids and barriers of the CNS.. 2022 Dec 15; 19(1):101. Epub 2022 Dec 15.
11/22/2022
Feng W, Zhang Y, Ding S, Chen S, Wang T, Wang Z, Zou Y, Sheng C, Chen Y, Pang Y, Marshall C, Shi J, Nedergaard M, Li Q, Xiao M. "B lymphocytes ameliorate Alzheimer's disease-like neuropathology via interleukin-35." Brain, behavior, and immunity.. 2022 Nov 22; Epub 2022 Nov 22.
10/27/2022
Ge GR, Song W, Nedergaard M, Rolland JP, Parker KJ. "Theory of sleep/wake cycles affecting brain elastography." Physics in medicine and biology.. 2022 Oct 27; Epub 2022 Oct 27.
10/24/2022
Wang X, Delle C, Asiminas A, Akther S, Vittani M, Brøgger P, Kusk P, Vo CT, Radovanovic T, Konno A, Hirai H, Fukuda M, Weikop P, Goldman SA, Nedergaard M, Hirase H. "Liver-secreted fluorescent blood plasma markers enable chronic imaging of the microcirculation." . 2022 Oct 24; 2(10):100302. Epub 2022 Sep 21.
10/21/2022
Lilius TO, Rosenholm M, Klinger L, Mortensen KN, Sigurdsson B, Mogensen FL, Hauglund NL, Nielsen MSN, Rantamäki T, Nedergaard M. "SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline." iScience.. 2022 Oct 21; 25(10):105250. Epub 2022 Sep 29.
10/21/2022
Persson NDÅ, Uusalo P, Nedergaard M, Lohela TJ, Lilius TO. "Could dexmedetomidine be repurposed as a glymphatic enhancer?" Trends in pharmacological sciences.. 2022 Oct 21; Epub 2022 Oct 21.
9/27/2022
Lopes van den Broek S, Shalgunov V, García Vázquez R, Beschorner N, Bidesi NSR, Nedergaard M, Knudsen GM, Sehlin D, Syvänen S, Herth MM. "Pretargeted Imaging beyond the Blood-Brain Barrier-Utopia or Feasible?" Pharmaceuticals.. 2022 Sep 27; 15(10)Epub 2022 Sep 27.
9/16/2022
Bohr T, Hjorth PG, Holst SC, Hrab?tová S, Kiviniemi V, Lilius T, Lundgaard I, Mardal KA, Martens EA, Mori Y, Nägerl UV, Nicholson C, Tannenbaum A, Thomas JH, Tithof J, Benveniste H, Iliff JJ, Kelley DH, Nedergaard M. "The glymphatic system: Current understanding and modeling." iScience.. 2022 Sep 16; 25(9):104987. Epub 2022 Aug 20.
9/14/2022
Carlsen EMM, Nedergaard M, Rasmussen RN. "Versatile treadmill system for measuring locomotion and neural activity in head-fixed mice." STAR protocols.. 2022 Sep 14; 3(4):101701. Epub 2022 Sep 14.
9/13/2022
Plá V, Bork P, Harnpramukkul A, Olveda G, Ladrón-de-Guevara A, Giannetto MJ, Hussain R, Wang W, Kelley DH, Hablitz LM, Nedergaard M. "A real-time in vivo clearance assay for quantification of glymphatic efflux." Cell reports.. 2022 Sep 13; 40(11):111320.
9/6/2022
Wu SY, Wen Y, Serre NBC, Laursen CCH, Dietz AG, Taylor BR, Drobizhev M, Molina RS, Aggarwal A, Rancic V, Becker M, Ballanyi K, Podgorski K, Hirase H, Nedergaard M, Fendrych M, Lemieux MJ, Eberl DF, Kay AR, Campbell RE, Shen Y. "A sensitive and specific genetically encoded potassium ion biosensor for in vivo applications across the tree of life." PLoS biology.. 2022 Sep 6; 20(9):e3001772. Epub 2022 Sep 06.
8/10/2022
Lohela TJ, Lilius TO, Nedergaard M. "The glymphatic system: implications for drugs for central nervous system diseases." Nature reviews. Drug discovery.. 2022 Aug 10; Epub 2022 Aug 10.
8/9/2022
Wostyn P, Mader TH, Gibson CR, Nedergaard M. "The effect of long-duration spaceflight on perivascular spaces within the brain." Proceedings of the National Academy of Sciences of the United States of America.. 2022 Aug 9; 119(32):e2207724119. Epub 2022 Jul 18.
7/7/2022
Kjaerby C, Andersen M, Hauglund N, Untiet V, Dall C, Sigurdsson B, Ding F, Feng J, Li Y, Weikop P, Hirase H, Nedergaard M. "Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine." Nature neuroscience.. 2022 Jul 7; Epub 2022 Jul 07.
7/6/2022
Mestre H, Verma N, Greene TD, Lin LA, Ladron-de-Guevara A, Sweeney AM, Liu G, Thomas VK, Galloway CA, de Mesy Bentley KL, Nedergaard M, Mehta RI. "Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer's disease." Nature communications.. 2022 Jul 6; 13(1):3897. Epub 2022 Jul 06.
5/20/2022
Tithof J, Boster KAS, Bork PAR, Nedergaard M, Thomas JH, Kelley DH. "A network model of glymphatic flow under different experimentally-motivated parametric scenarios." iScience.. 2022 May 20; 25(5):104258. Epub 2022 Apr 14.
5/14/2022
Kananen J, Järvelä M, Korhonen V, Tuovinen T, Huotari N, Raitamaa L, Helakari H, Väyrynen T, Raatikainen V, Nedergaard M, Ansakorpi H, Jacobs J, LeVan P, Kiviniemi V. "Increased interictal synchronicity of respiratory related brain pulsations in epilepsy." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2022 May 14; :271678X221099703. Epub 2022 May 14.
3/23/2022
Ladrón-de-Guevara A, Shang JK, Nedergaard M, Kelley DH. "Perivascular pumping in the mouse brain: Improved boundary conditions reconcile theory, simulation, and experiment." Journal of theoretical biology.. 2022 Mar 23; :111103. Epub 2022 Mar 23.
3/18/2022
Monai H, Koketsu S, Shinohara Y, Ueki T, Kusk P, Hauglund NL, Samson AJ, Nedergaard M, Hirase H. "Author Correction: Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization." Scientific reports.. 2022 Mar 18; 12(1):4741. Epub 2022 Mar 18.
2/23/2022
Beaman EE, Bonde AN, Ulv Larsen SM, Ozenne B, Lohela TJ, Nedergaard M, Gíslason GH, Knudsen GM, Holst SC. "Blood-brain barrier permeable ?-blockers linked to lower risk of Alzheimer's disease in hypertension." Brain : a journal of neurology.. 2022 Feb 23; Epub 2022 Feb 23.
2/7/2022
Helakari H, Korhonen V, Holst SC, Piispala J, Kallio M, Väyrynen T, Huotari N, Raitamaa L, Tuunanen J, Kananen J, Järvelä M, Tuovinen T, Raatikainen V, Borchardt V, Kinnunen H, Nedergaard M, Kiviniemi V. "Human NREM Sleep Promotes Brain-Wide Vasomotor and Respiratory Pulsations." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2022 Feb 7; Epub 2022 Feb 07.
2022
Wostyn P, Mader TH, Gibson CR, Nedergaard M. "Does Long-Duration Exposure to Microgravity Lead to Dysregulation of the Brain and Ocular Glymphatic Systems?" Eye and brain.. 2022 14:49-58. Epub 2022 May 04.
2022
Newell DW, Nedergaard M, Aaslid R. "Physiological Mechanisms and Significance of Intracranial B Waves." Frontiers in neurology. 2022 13:872701. Epub 2022 May 16.
12/28/2021
Martikainen MV, Aakko-Saksa P, van den Broek L, Cassee FR, Carare RO, Chew S, Dinnyes A, Giugno R, Kanninen KM, Malm T, Muala A, Nedergaard M, Oudin A, Oyola P, Pfeiffer TV, Rönkkö T, Saarikoski S, Sandström T, Schins RPF, Topinka J, Yang M, Zeng X, Westerink RHS, Jalava PI. "TUBE Project: Transport-Derived Ultrafines and the Brain Effects." International journal of environmental research and public health.. 2021 Dec 28; 19(1)Epub 2021 Dec 28.
10/26/2021
Battistella R, Kritsilis M, Matuskova H, Haswell D, Cheng AX, Meissner A, Nedergaard M, Lundgaard I. "Not All Lectins Are Equally Suitable for Labeling Rodent Vasculature." International journal of molecular sciences.. 2021 Oct 26; 22(21)Epub 2021 Oct 26.
10/25/2021
Hablitz LM, Nedergaard M. "The glymphatic system." Current biology : CB.. 2021 Oct 25; 31(20):R1371-R1375.
9/28/2021
Du T, Mestre H, Kress BT, Liu G, Sweeney AM, Samson AJ, Rasmussen MK, Mortensen KN, Bork PAR, Peng W, Olveda GE, Bashford L, Toro ER, Tithof J, Kelley DH, Thomas JH, Hjorth PG, Martens EA, Mehta RI, Hirase H, Mori Y, Nedergaard M. "Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema." Brain : a journal of neurology.. 2021 Sep 28; Epub 2021 Sep 28.
9/15/2021
Hablitz LM, Nedergaard M. "The Glymphatic System: A Novel Component of Fundamental Neurobiology." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2021 Sep 15; 41(37):7698-7711.
8/16/2021
Pavan C, Xavier AL, Ramos M, Fisher J, Kritsilis M, Linder A, Bentzer P, Nedergaard M, Lundgaard I. "DNase treatment prevents CSF block in early experimental pneumococcal meningitis." Annals of neurology.. 2021 Aug 16; Epub 2021 Aug 16.
8/15/2021
Benveniste H, Nedergaard M. "Cerebral small vessel disease: A glymphopathy?" Current opinion in neurobiology.. 2021 Aug 15; 72:15-21. Epub 2021 Aug 15.
7/13/2021
Mogensen FL, Delle C, Nedergaard M. "The Glymphatic System (En)during Inflammation." International journal of molecular sciences.. 2021 Jul 13; 22(14)Epub 2021 Jul 13.
7/12/2021
Wardlaw JM, Benveniste H, Nedergaard M, Zlokovic BV, Charpak S, Smith KJ, Black SE. "Reply to: Rethink the classical view of cerebrospinal fluid production." Nature reviews. Neurology.. 2021 Jul 12; Epub 2021 Jul 12.
5/5/2021
Rasmussen MK, Mestre H, Nedergaard M. "Fluid Transport in the Brain." Physiological reviews.. 2021 May 5; Epub 2021 May 05.
4/14/2021
Monai H, Koketsu S, Shinohara Y, Ueki T, Kusk P, Hauglund NL, Samson AJ, Nedergaard M, Hirase H. "Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization." Scientific reports.. 2021 Apr 14; 11(1):8150. Epub 2021 Apr 14.
3/31/2021
Rajna Z, Mattila H, Huotari N, Tuovinen T, Krüger J, Holst SC, Korhonen V, Remes AM, Seppänen T, Hennig J, Nedergaard M, Kiviniemi V. "Cardiovascular brain impulses in Alzheimer's disease." Brain : a journal of neurology.. 2021 Mar 31; Epub 2021 Mar 31.
3/19/2021
Yuste R, Hawrylycz M, Aalling N, Aguilar-Valles A, Arendt D, Armañanzas R, Ascoli GA, Bielza C, Bokharaie V, Bergmann TB, Bystron I, Capogna M, Chang Y, Clemens A, de Kock CPJ, DeFelipe J, Dos Santos SE, Dunville K, Feldmeyer D, Fiáth R, Fishell GJ, Foggetti A, Gao X, Ghaderi P, Goriounova NA, Güntürkün O, Hagihara K, Hall VJ, Helmstaedter M, Herculano-Houzel S, Hilscher MM, Hirase H, Hjerling-Leffler J, Hodge R, Huang J, Huda R, Khodosevich K, Kiehn O, Koch H, Kuebler ES, Kühnemund M, Larrañaga P, Lelieveldt B, Louth EL, Lui JH, Mansvelder HD, Marin O, Martinez-Trujillo J, Chameh HM, Mohapatra AN, Munguba H, Nedergaard M, N?mec P, Ofer N, Pfisterer UG, Pontes S, Redmond W, Rossier J, Sanes JR, Scheuermann RH, Serrano-Saiz E, Staiger JF, Somogyi P, Tamás G, Tolias AS, Tosches MA, García MT, Wozny C, Wuttke TV, Liu Y, Yuan J, Zeng H, Lein E. "Author Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types." Nature neuroscience.. 2021 Mar 19; Epub 2021 Mar 19.
3/9/2021
Raghunandan A, Ladron-de-Guevara A, Tithof J, Mestre H, Du T, Nedergaard M, Thomas JH, Kelley DH. "Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection." eLife.. 2021 Mar 9; 10Epub 2021 Mar 09.
1/11/2021
Stanton EH, Persson NDÅ, Gomolka RS, Lilius T, Sigurðsson B, Lee H, Xavier ALR, Benveniste H, Nedergaard M, Mori Y. "Mapping of CSF transport using high spatiotemporal resolution dynamic contrast-enhanced MRI in mice: Effect of anesthesia." Magnetic resonance in medicine.. 2021 Jan 11; Epub 2021 Jan 11.
12/22/2020
Liu G, Mestre H, Sweeney AM, Sun Q, Weikop P, Du T, Nedergaard M. "Direct Measurement of Cerebrospinal Fluid Production in Mice." Cell reports.. 2020 Dec 22; 33(12):108524.
12/9/2020
Tuovinen T, Kananen J, Rajna Z, Lieslehto J, Korhonen V, Rytty R, Mattila H, Huotari N, Raitamaa L, Helakari H, Elseoud AA, Krüger J, LeVan P, Tervonen O, Hennig J, Remes AM, Nedergaard M, Kiviniemi V. "The variability of functional MRI brain signal increases in Alzheimer's disease at cardiorespiratory frequencies." Scientific reports.. 2020 Dec 9; 10(1):21559. Epub 2020 Dec 09.
12/4/2020
Yuste R, Hawrylycz M, Aalling N, Aguilar-Valles A, Arendt D, Arnedillo RA, Ascoli GA, Bielza C, Bokharaie V, Bergmann TB, Bystron I, Capogna M, Chang Y, Clemens A, de Kock CPJ, DeFelipe J, Dos Santos SE, Dunville K, Feldmeyer D, Fiáth R, Fishell GJ, Foggetti A, Gao X, Ghaderi P, Goriounova NA, Güntürkün O, Hagihara K, Hall VJ, Helmstaedter M, Herculano S, Hilscher MM, Hirase H, Hjerling-Leffler J, Hodge R, Huang J, Huda R, Khodosevich K, Kiehn O, Koch H, Kuebler ES, Kühnemund M, Larrañaga P, Lelieveldt B, Louth EL, Lui JH, Mansvelder HD, Marin O, Martinez-Trujillo J, Moradi Chameh H, Nath A, Nedergaard M, N?mec P, Ofer N, Pfisterer UG, Pontes S, Redmond W, Rossier J, Sanes JR, Scheuermann R, Serrano-Saiz E, Steiger JF, Somogyi P, Tamás G, Tolias AS, Tosches MA, García MT, Vieira HM, Wozny C, Wuttke TV, Yong L, Yuan J, Zeng H, Lein E. "Publisher Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types." Nature neuroscience.. 2020 Dec 4; Epub 2020 Dec 04.
12/1/2020
Goldman N, Hablitz LM, Mori Y, Nedergaard M. "The Glymphatic System and Pain." Medical acupuncture.. 2020 Dec 1; 32(6):373-376. Epub 2020 Dec 16.
11/2020
Min Rivas F, Liu J, Martell BC, Du T, Mestre H, Nedergaard M, Tithof J, Thomas JH, Kelley DH. "Surface periarterial spaces of the mouse brain are open, not porous." Journal of the Royal Society, Interface. 2020 Nov; 17(172):20200593. Epub 2020 Nov 11.
10/2/2020
Nedergaard M, Goldman SA. "Glymphatic failure as a final common pathway to dementia." Science.. 2020 Oct 2; 370(6512):50-56.
9/30/2020
Giannetto M, Xia M, Stæger FF, Metcalfe T, Vinitsky HS, Dang JAML, Xavier ALR, Kress BT, Nedergaard M, Hablitz LM. "Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice." Scientific reports.. 2020 Sep 30; 10(1):16073. Epub 2020 Sep 30.
9/2/2020
Hablitz LM, Plá V, Giannetto M, Vinitsky HS, Stæger FF, Metcalfe T, Nguyen R, Benrais A, Nedergaard M. "Circadian control of brain glymphatic and lymphatic fluid flow." Nature communications.. 2020 Sep 2; 11(1):4411. Epub 2020 Sep 02.
8/24/2020
Yuste R, Hawrylycz M, Aalling N, Aguilar-Valles A, Arendt D, Arnedillo RA, Ascoli GA, Bielza C, Bokharaie V, Bergmann TB, Bystron I, Capogna M, Chang Y, Clemens A, de Kock CPJ, DeFelipe J, Dos Santos SE, Dunville K, Feldmeyer D, Fiáth R, Fishell GJ, Foggetti A, Gao X, Ghaderi P, Goriounova NA, Güntürkün O, Hagihara K, Hall VJ, Helmstaedter M, Herculano S, Hilscher MM, Hirase H, Hjerling-Leffler J, Hodge R, Huang J, Huda R, Khodosevich K, Kiehn O, Koch H, Kuebler ES, Kühnemund M, Larrañaga P, Lelieveldt B, Louth EL, Lui JH, Mansvelder HD, Marin O, Martinez-Trujillo J, Moradi Chameh H, Nath A, Nedergaard M, N?mec P, Ofer N, Pfisterer UG, Pontes S, Redmond W, Rossier J, Sanes JR, Scheuermann R, Serrano-Saiz E, Steiger JF, Somogyi P, Tamás G, Tolias AS, Tosches MA, García MT, Vieira HM, Wozny C, Wuttke TV, Yong L, Yuan J, Zeng H, Lein E. "A community-based transcriptomics classification and nomenclature of neocortical cell types." Nature neuroscience.. 2020 Aug 24; Epub 2020 Aug 24.
8/20/2020
Ng Kee Kwong KC, Mehta AR, Nedergaard M, Chandran S. "Defining novel functions for cerebrospinal fluid in ALS pathophysiology." Acta neuropathologica communications.. 2020 Aug 20; 8(1):140. Epub 2020 Aug 20.
7/24/2020
Rangroo Thrane V, Hynnekleiv L, Wang X, Thrane AS, Krohn J, Nedergaard M. "Twists and turns of ocular glymphatic clearance - new study reveals surprising findings in glaucoma." Acta ophthalmologica.. 2020 Jul 24; Epub 2020 Jul 24.
7/13/2020
Stæger FF, Mortensen KN, Nielsen MSN, Sigurdsson B, Kaufmann LK, Hirase H, Nedergaard M. "A three-dimensional, population-based average of the C57BL/6 mouse brain from DAPI-stained coronal slices." Scientific data.. 2020 Jul 13; 7(1):235. Epub 2020 Jul 13.
5/19/2020
Windrem MS, Schanz SJ, Zou L, Chandler-Militello D, Kuypers NJ, Nedergaard M, Lu Y, Mariani JN, Goldman SA. "Human Glial Progenitor Cells Effectively Remyelinate the Demyelinated Adult Brain." Cell reports.. 2020 May 19; 31(7):107658.
5/15/2020
Mestre H, Mori Y, Nedergaard M. "The Brain's Glymphatic System: Current Controversies." Trends in neurosciences.. 2020 May 15; Epub 2020 May 15.
5/12/2020
Rasmussen R, O'Donnell J, Ding F, Nedergaard M. "Interstitial ions: A key regulator of state-dependent neural activity?" Progress in neurobiology.. 2020 May 12; :101802. Epub 2020 May 12.
5/2020
Ulv Larsen SM, Landolt HP, Berger W, Nedergaard M, Knudsen GM, Holst SC. "Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep." PLoS biology.. 2020 May; 18(5):e3000623. Epub 2020 May 05.
3/31/2020
Viggiano D, Wagner CA, Martino G, Nedergaard M, Zoccali C, Unwin R, Capasso G. "Mechanisms of cognitive dysfunction in CKD." Nature reviews. Nephrology.. 2020 Mar 31; Epub 2020 Mar 31.
3/25/2020
Wang X, Lou N, Eberhardt A, Yang Y, Kusk P, Xu Q, Förstera B, Peng S, Shi M, Ladrón-de-Guevara A, Delle C, Sigurdsson B, Xavier ALR, Ertürk A, Libby RT, Chen L, Thrane AS, Nedergaard M. "An ocular glymphatic clearance system removes ?-amyloid from the rodent eye." Science translational medicine.. 2020 Mar 25; 12(536)
3/11/2020
Hauglund NL, Kusk P, Kornum BR, Nedergaard M. "Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2020 Mar 11; 40(11):2371-2380. Epub 2020 Feb 11.
3/9/2020
Karimy JK, Reeves BC, Damisah E, Duy PQ, Antwi P, David W, Wang K, Schiff SJ, Limbrick DD, Alper SL, Warf BC, Nedergaard M, Simard JM, Kahle KT. "Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets." Nature reviews. Neurology.. 2020 Mar 9; Epub 2020 Mar 09.
3/2020
Reeves BC, Karimy JK, Kundishora AJ, Mestre H, Cerci HM, Matouk C, Alper SL, Lundgaard I, Nedergaard M, Kahle KT. "Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus." Trends in molecular medicine.. 2020 Mar; 26(3):285-295. Epub 2020 Jan 18.
2/27/2020
Koundal S, Elkin R, Nadeem S, Xue Y, Constantinou S, Sanggaard S, Liu X, Monte B, Xu F, Nostrand WV, Nedergaard M, Lee H, Wardlaw J, Benveniste H, Tannenbaum A. "Publisher Correction: Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System." Scientific reports.. 2020 Feb 27; 10(1):3934. Epub 2020 Feb 27.
2/24/2020
Wardlaw JM, Benveniste H, Nedergaard M, Zlokovic BV, Mestre H, Lee H, Doubal FN, Brown R, Ramirez J, MacIntosh BJ, Tannenbaum A, Ballerini L, Rungta RL, Boido D, Sweeney M, Montagne A, Charpak S, Joutel A, Smith KJ, Black SE, . "Perivascular spaces in the brain: anatomy, physiology and pathology." Nature reviews. Neurology.. 2020 Feb 24; Epub 2020 Feb 24.
2/11/2020
Li Q, Aalling NN, Förstera B, Ertürk A, Nedergaard M, Møllgård K, Xavier ALR. "Aquaporin 1 and the Na/K/2Cl cotransporter 1 are present in the leptomeningeal vasculature of the adult rodent central nervous system." Fluids and barriers of the CNS.. 2020 Feb 11; 17(1):15. Epub 2020 Feb 11.
2/6/2020
Koundal S, Elkin R, Nadeem S, Xue Y, Constantinou S, Sanggaard S, Liu X, Monte B, Xu F, Van Nostrand W, Nedergaard M, Lee H, Wardlaw J, Benveniste H, Tannenbaum A. "Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System." Scientific reports.. 2020 Feb 6; 10(1):1990. Epub 2020 Feb 06.
1/30/2020
Mestre H, Du T, Sweeney AM, Liu G, Samson AJ, Peng W, Mortensen KN, Stæger FF, Bork PAR, Bashford L, Toro ER, Tithof J, Kelley DH, Thomas JH, Hjorth PG, Martens EA, Mehta RI, Solis O, Blinder P, Kleinfeld D, Hirase H, Mori Y, Nedergaard M. "Cerebrospinal fluid influx drives acute ischemic tissue swelling." Science.. 2020 Jan 30; Epub 2020 Jan 30.
2020
Kananen J, Helakari H, Korhonen V, Huotari N, Järvelä M, Raitamaa L, Raatikainen V, Rajna Z, Tuovinen T, Nedergaard M, Jacobs J, LeVan P, Ansakorpi H, Kiviniemi V. "Respiratory-related brain pulsations are increased in epilepsy-a two-centre functional MRI study." Brain communications.. 2020 2(2):fcaa076. Epub 2020 Jun 08.
12/1/2019
Yoon C, Qi Y, Mestre H, Canavesi C, Marola OJ, Cogliati A, Nedergaard M, Libby RT, Rolland JP. "Gabor domain optical coherence microscopy combined with laser scanning confocal fluorescence microscopy." Biomedical optics express.. 2019 Dec 1; 10(12):6242-6257. Epub 2019 Nov 14.
11/5/2019
Dietz AG, Goldman SA, Nedergaard M. "Glial cells in schizophrenia: a unified hypothesis." The lancet. Psychiatry.. 2019 Nov 5; Epub 2019 Nov 05.
11/2019
Ji RR, Donnelly CR, Nedergaard M. "Astrocytes in chronic pain and itch." Nature reviews. Neuroscience.. 2019 Nov; 20(11):667-685. Epub 2019 Sep 19.
8/7/2019
Mortensen KN, Sanggaard S, Mestre H, Lee H, Kostrikov S, Xavier ALR, Gjedde A, Benveniste H, Nedergaard M. "Impaired Glymphatic Transport in Spontaneously Hypertensive Rats." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2019 Aug 7; 39(32):6365-6377. Epub 2019 Jun 17.
8/2019
Grutzendler J, Nedergaard M. "Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas." Trends in neurosciences.. 2019 Aug; 42(8):528-536. Epub 2019 Jun 26.
7/30/2019
Rasmussen R, Nicholas E, Petersen NC, Dietz AG, Xu Q, Sun Q, Nedergaard M. "Cortex-wide Changes in Extracellular Potassium Ions Parallel Brain State Transitions in Awake Behaving Mice." Cell reports.. 2019 Jul 30; 28(5):1182-1194.e4.
7/29/2019
Sweeney AM, Plá V, Du T, Liu G, Sun Q, Peng S, Plog BA, Kress BT, Wang X, Mestre H, Nedergaard M. "In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy." Journal of visualized experiments : JoVE.. 2019 Jul 29; (149)Epub 2019 Jul 29.
7/1/2019
Zvietcovich F, Ge GR, Mestre H, Giannetto M, Nedergaard M, Rolland JP, Parker KJ. "Longitudinal shear waves for elastic characterization of tissues in optical coherence elastography." Biomedical optics express.. 2019 Jul 1; 10(7):3699-3718. Epub 2019 Jul 01.
6/28/2019
Lilius TO, Blomqvist K, Hauglund NL, Liu G, Stæger FF, Bærentzen S, Du T, Ahlström F, Backman JT, Kalso EA, Rauhala PV, Nedergaard M. "Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs." Journal of controlled release : official journal of the Controlled Release Society.. 2019 Jun 28; 304:29-38. Epub 2019 May 05.
6/28/2019
Smith NA, Bekar LK, Nedergaard M. "Astrocytic Endocannabinoids Mediate Hippocampal Transient Heterosynaptic Depression." Neurochemical research.. 2019 Jun 28; Epub 2019 Jun 28.
6/25/2019
Liu Z, Osipovitch M, Benraiss A, Huynh NPT, Foti R, Bates J, Chandler-Militello D, Findling RL, Tesar PJ, Nedergaard M, Windrem MS, Goldman SA. "Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling." Cell reports.. 2019 Jun 25; 27(13):3832-3843.e6.
6/20/2019
Tithof J, Kelley DH, Mestre H, Nedergaard M, Thomas JH. "Hydraulic resistance of periarterial spaces in the brain." Fluids and barriers of the CNS.. 2019 Jun 20; 16(1):19. Epub 2019 Jun 20.
5/28/2019
Monai H, Wang X, Yahagi K, Lou N, Mestre H, Xu Q, Abe Y, Yasui M, Iwai Y, Nedergaard M, Hirase H. "Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke." Proceedings of the National Academy of Sciences of the United States of America.. 2019 May 28; 116(22):11010-11019. Epub 2019 May 16.
5/17/2019
Plog BA, Lou N, Pierre CA, Cove A, Kenney HM, Hitomi E, Kang H, Iliff JJ, Zeppenfeld DM, Nedergaard M, Vates GE. "When the air hits your brain: decreased arterial pulsatility after craniectomy leading to impaired glymphatic flow." Journal of neurosurgery.. 2019 May 17; :1-14. Epub 2019 May 17.
5/2019
Zhou S, Giannetto M, DeCourcey J, Kang H, Kang N, Li Y, Zheng S, Zhao H, Simmons WR, Wei HS, Bodine DM, Low PS, Nedergaard M, Wan J. "Oxygen tension-mediated erythrocyte membrane interactions regulate cerebral capillary hyperemia." Science advances.. 2019 May; 5(5):eaaw4466. Epub 2019 May 29.
3/12/2019
Munk AS, Wang W, Bèchet NB, Eltanahy AM, Cheng AX, Sigurdsson B, Benraiss A, Mäe MA, Kress BT, Kelley DH, Betsholtz C, Møllgård K, Meissner A, Nedergaard M, Lundgaard I. "PDGF-B Is Required for Development of the Glymphatic System." Cell reports.. 2019 Mar 12; 26(11):2955-2969.e3.
2/2019
Cai R, Pan C, Ghasemigharagoz A, Todorov MI, Förstera B, Zhao S, Bhatia HS, Parra-Damas A, Mrowka L, Theodorou D, Rempfler M, Xavier ALR, Kress BT, Benakis C, Steinke H, Liebscher S, Bechmann I, Liesz A, Menze B, Kerschensteiner M, Nedergaard M, Ertürk A. "Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections." Nature neuroscience.. 2019 Feb; 22(2):317-327. Epub 2018 Dec 31.
2/2019
Hablitz LM, Vinitsky HS, Sun Q, Stæger FF, Sigurdsson B, Mortensen KN, Lilius TO, Nedergaard M. "Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia." Science advances.. 2019 Feb; 5(2):eaav5447. Epub 2019 Feb 27.
1/25/2019
Koundal S, Liu X, Sanggaard S, Mortensen K, Wardlaw J, Nedergaard M, Benveniste H, Lee H. "Brain morphometry and longitudinal relaxation time of spontaneously hypertensive rats (SHR) in early and intermediate stages of hypertension investigated by 3D VFA-SPGR MRI." Neuroscience.. 2019 Jan 25; Epub 2019 Jan 25.
1/2019
Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, Benveniste H, Dichgans M, Iadecola C, Love S, Bath PM, Markus HS, Salman RA, Allan SM, Quinn TJ, Kalaria RN, Werring DJ, Carare RO, Touyz RM, Williams SCR, Moskowitz MA, Katusic ZS, Lutz SE, Lazarov O, Minshall RD, Rehman J, Davis TP, Wellington CL, González HM, Yuan C, Lockhart SN, Hughes TM, Chen CLH, Sachdev P, O'Brien JT, Skoog I, Pantoni L, Gustafson DR, Biessels GJ, Wallin A, Smith EE, Mok V, Wong A, Passmore P, Barkof F, Muller M, Breteler MMB, Román GC, Hamel E, Seshadri S, Gottesman RF, van Buchem MA, Arvanitakis Z, Schneider JA, Drewes LR, Hachinski V, Finch CE, Toga AW, Wardlaw JM, Zlokovic BV. "Vascular dysfunction-The disregarded partner of Alzheimer's disease." Alzheimer's & dementia : the journal of the Alzheimer's Association.. 2019 Jan; 15(1):158-167.
2019
Ramos M, Burdon Bechet N, Battistella R, Pavan C, Xavier ALR, Nedergaard M, Lundgaard I. "Cisterna Magna Injection in Rats to Study Glymphatic Function." Methods in molecular biology.. 2019 1938:97-104.
2019
Wang M, Qin C, Luo X, Wang J, Wang X, Xie M, Hu J, Cao J, Hu T, Goldman SA, Nedergaard M, Wang W. "Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease." Theranostics.. 2019 9(15):4474-4493. Epub 2019 Jun 09.
2019
DiNuzzo M, Walls AB, Öz G, Seaquist ER, Waagepetersen HS, Bak LK, Nedergaard M, Schousboe A. "State-Dependent Changes in Brain Glycogen Metabolism." Advances in neurobiology.. 2019 23:269-309.
2019
Verkhratsky A, Nedergaard M, Steardo L, Li B. "Editorial: Sleep and Mood Disorders." Frontiers in psychiatry.. 2019 10:981. Epub 2020 Jan 16.
12/18/2018
Mestre H, Hablitz LM, Xavier AL, Feng W, Zou W, Pu T, Monai H, Murlidharan G, Castellanos Rivera RM, Simon MJ, Pike MM, Plá V, Du T, Kress BT, Wang X, Plog BA, Thrane AS, Lundgaard I, Abe Y, Yasui M, Thomas JH, Xiao M, Hirase H, Asokan A, Iliff JJ, Nedergaard M. "Aquaporin-4-dependent glymphatic solute transport in the rodent brain." eLife.. 2018 Dec 18; 7Epub 2018 Dec 18.
12/6/2018
Plog BA, Mestre H, Olveda GE, Sweeney AM, Kenney HM, Cove A, Dholakia KY, Tithof J, Nevins TD, Lundgaard I, Du T, Kelley DH, Nedergaard M. "Transcranial optical imaging reveals a pathway for optimizing the delivery of immunotherapeutics to the brain." JCI insight.. 2018 Dec 6; 3(23)Epub 2018 Dec 06.
11/19/2018
Mestre H, Tithof J, Du T, Song W, Peng W, Sweeney AM, Olveda G, Thomas JH, Nedergaard M, Kelley DH. "Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension." Nature communications.. 2018 Nov 19; 9(1):4878. Epub 2018 Nov 19.
11/2018
Rasmussen MK, Mestre H, Nedergaard M. "The glymphatic pathway in neurological disorders." The Lancet. Neurology.. 2018 Nov; 17(11):1016-1024.
10/18/2018
Plog BA, Mestre H, Olveda GE, Sweeney AM, Kenney HM, Cove A, Dholakia KY, Tithof J, Nevins TD, Lundgaard I, Du T, Kelley DH, Nedergaard M. "Transcranial optical imaging reveals a pathway for optimizing the delivery of immunotherapeutics to the brain." JCI insight.. 2018 Oct 18; 3(20)Epub 2018 Oct 18.
10/9/2018
Michaelsen SR, Staberg M, Pedersen H, Jensen KE, Majewski W, Broholm H, Nedergaard MK, Meulengracht C, Urup T, Villingshøj M, Lukacova S, Skjøth-Rasmussen J, Brennum J, Kjær A, Lassen U, Stockhausen MT, Poulsen HS, Hamerlik P. "VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance." Neuro-oncology.. 2018 Oct 9; 20(11):1462-1474.
9/1/2018
Brown R, Benveniste H, Black SE, Charpak S, Dichgans M, Joutel A, Nedergaard M, Smith KJ, Zlokovic BV, Wardlaw JM. "Understanding the role of the perivascular space in cerebral small vessel disease." Cardiovascular research.. 2018 Sep 1; 114(11):1462-1473.
9/2018
Obara-Michlewska M, Ding F, Popek M, Verkhratsky A, Nedergaard M, Zielinska M, Albrecht J. "Interstitial ion homeostasis and acid-base balance are maintained in oedematous brain of mice with acute toxic liver failure." Neurochemistry international.. 2018 Sep; 118:286-291. Epub 2018 May 14.
9/2018
Kananen J, Tuovinen T, Ansakorpi H, Rytky S, Helakari H, Huotari N, Raitamaa L, Raatikainen V, Rasila A, Borchardt V, Korhonen V, LeVan P, Nedergaard M, Kiviniemi V. "Altered physiological brain variation in drug-resistant epilepsy." Brain and behavior.. 2018 Sep; 8(9):e01090. Epub 2018 Aug 15.
7/16/2018
Aalling NN, Nedergaard M, DiNuzzo M. "Cerebral Metabolic Changes During Sleep." Current neurology and neuroscience reports.. 2018 Jul 16; 18(9):57. Epub 2018 Jul 16.
5/23/2018
Xavier ALR, Hauglund NL, von Holstein-Rathlou S, Li Q, Sanggaard S, Lou N, Lundgaard I, Nedergaard M. "Cannula Implantation into the Cisterna Magna of Rodents." Journal of visualized experiments : JoVE.. 2018 May 23; (135)Epub 2018 May 23.
4/30/2018
Horsburgh K, Wardlaw JM, van Agtmael T, Allan SM, Ashford MLJ, Bath PM, Brown R, Berwick J, Cader MZ, Carare RO, Davis JB, Duncombe J, Farr TD, Fowler JH, Goense J, Granata A, Hall CN, Hainsworth AH, Harvey A, Hawkes CA, Joutel A, Kalaria RN, Kehoe PG, Lawrence CB, Lockhart A, Love S, Macleod MR, Macrae IM, Markus HS, McCabe C, McColl BW, Meakin PJ, Miller A, Nedergaard M, O'Sullivan M, Quinn TJ, Rajani R, Saksida LM, Smith C, Smith KJ, Touyz RM, Trueman RC, Wang T, Williams A, Williams SCR, Work LM. "Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology." Clinical science.. 2018 Apr 30; 132(8):851-868. Epub 2018 Apr 30.
3/2018
Lee H, Mortensen K, Sanggaard S, Koch P, Brunner H, Quistorff B, Nedergaard M, Benveniste H. "Quantitative Gd-DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA-SPGR at 9.4T." Magnetic resonance in medicine.. 2018 Mar; 79(3):1568-1578. Epub 2017 Jun 19.
2/2/2018
Lundgaard I, Wang W, Eberhardt A, Vinitsky HS, Reeves BC, Peng S, Lou N, Hussain R, Nedergaard M. "Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function." Scientific reports.. 2018 Feb 2; 8(1):2246. Epub 2018 Feb 02.
1/30/2018
Smith NA, Kress BT, Lu Y, Chandler-Militello D, Benraiss A, Nedergaard M. "Fluorescent Ca indicators directly inhibit the Na,K-ATPase and disrupt cellular functions." Science signaling.. 2018 Jan 30; 11(515)Epub 2018 Jan 30.
1/24/2018
Plog BA, Nedergaard M. "The Glymphatic System in Central Nervous System Health and Disease: Past, Present, and Future." Annual review of pathology.. 2018 Jan 24; 13:379-394.
1/1/2018
Holstein-Rathlou SV, Petersen NC, Nedergaard M. "Voluntary running enhances glymphatic influx in awake behaving, young mice." Neuroscience letters.. 2018 Jan 1; 662:253-258. Epub 2017 Oct 25.
1/1/2018
Verkhratsky A, Nedergaard M. "Physiology of Astroglia." Physiological reviews.. 2018 Jan 1; 98(1):239-389.
12/2017
Benveniste H, Lee H, Ding F, Sun Q, Al-Bizri E, Makaryus R, Probst S, Nedergaard M, Stein EA, Lu H. "Anesthesia with Dexmedetomidine and Low-dose Isoflurane Increases Solute Transport via the Glymphatic Pathway in Rat Brain When Compared with High-dose Isoflurane." Anesthesiology.. 2017 Dec; 127(6):976-988.
12/2017
DiNuzzo M, Nedergaard M. "Brain energetics during the sleep-wake cycle." Current opinion in neurobiology.. 2017 Dec; 47:65-72. Epub 2017 Oct 09.
9/1/2017
Mestre H, Kostrikov S, Mehta RI, Nedergaard M. "Perivascular spaces, glymphatic dysfunction, and small vessel disease." Clinical science.. 2017 Sep 1; 131(17):2257-2274. Epub 2017 Aug 10.
9/1/2017
Louveau A, Plog BA, Antila S, Alitalo K, Nedergaard M, Kipnis J. "Understanding the functions and relationships of the glymphatic system and meningeal lymphatics." The Journal of clinical investigation.. 2017 Sep 1; 127(9):3210-3219. Epub 2017 Sep 01.
9/2017
de Leon MJ, Li Y, Okamura N, Tsui WH, Saint Louis LA, Glodzik L, Osorio RS, Fortea J, Butler T, Pirraglia E, Fossati S, Kim HJ, Carare RO, Nedergaard M, Benveniste H, Rusinek H. "Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET." Journal of nuclear medicine : official publication, Society of Nuclear Medicine.. 2017 Sep; 58(9):1471-1476. Epub 2017 Mar 16.
9/2017
Oberheim Bush NA, Nedergaard M. "Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?" Neurochemical research.. 2017 Sep; 42(9):2577-2587. Epub 2017 Aug 19.
8/3/2017
Windrem MS, Osipovitch M, Liu Z, Bates J, Chandler-Militello D, Zou L, Munir J, Schanz S, McCoy K, Miller RH, Wang S, Nedergaard M, Findling RL, Tesar PJ, Goldman SA. "Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia." Cell stem cell.. 2017 Aug 3; 21(2):195-208.e6. Epub 2017 Jul 20.
6/2017
Lundgaard I, Lu ML, Yang E, Peng W, Mestre H, Hitomi E, Deane R, Nedergaard M. "Glymphatic clearance controls state-dependent changes in brain lactate concentration." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2017 Jun; 37(6):2112-2124. Epub 2016 Jan 01.
6/2017
Kjaerby C, Rasmussen R, Andersen M, Nedergaard M. "Does Global Astrocytic Calcium Signaling Participate in Awake Brain State Transitions and Neuronal Circuit Function?" Neurochemical research.. 2017 Jun; 42(6):1810-1822. Epub 2017 Feb 16.
5/15/2017
Ratner V, Gao Y, Lee H, Elkin R, Nedergaard M, Benveniste H, Tannenbaum A. "Cerebrospinal and interstitial fluid transport via the glymphatic pathway modeled by optimal mass transport." NeuroImage.. 2017 May 15; 152:530-537. Epub 2017 Mar 18.
4/26/2017
Sun W, Cornwell A, Li J, Peng S, Osorio MJ, Su Wanga NA, Benraiss A, Lou N, Goldman SA, Nedergaard M. "SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2017 Apr 26; 37(17):4493-4507. Epub 2017 Mar 23.
4/2017
Jiang Q, Zhang L, Ding G, Davoodi-Bojd E, Li Q, Li L, Sadry N, Nedergaard M, Chopp M, Zhang Z. "Impairment of the glymphatic system after diabetes." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2017 Apr; 37(4):1326-1337. Epub 2016 Jan 01.
4/2017
Wang F, Wang X, Shapiro LA, Cotrina ML, Liu W, Wang EW, Gu S, Wang W, He X, Nedergaard M, Huang JH. "NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility." Brain structure & function.. 2017 Apr; 222(3):1543-1556. Epub 2016 Sep 01.
3/15/2017
Wang M, Ding F, Deng S, Guo X, Wang W, Iliff JJ, Nedergaard M. "Focal Solute Trapping and Global Glymphatic Pathway Impairment in a Murine Model of Multiple Microinfarcts." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2017 Mar 15; 37(11):2870-2877. Epub 2017 Feb 10.
2/20/2017
Cotrina ML, Lou N, Tome-Garcia J, Goldman J, Nedergaard M. "Direct comparison of microglial dynamics and inflammatory profile in photothrombotic and arterial occlusion evoked stroke." Neuroscience.. 2017 Feb 20; 343:483-494. Epub 2016 Dec 18.
1/12/2017
Achariyar TM, Li B, Peng W, Verghese PB, Shi Y, McConnell E, Benraiss A, Kasper T, Song W, Takano T, Holtzman DM, Nedergaard M, Deane R. "Erratum to: Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation." Molecular neurodegeneration.. 2017 Jan 12; 12(1):3. Epub 2017 Jan 12.
12/8/2016
Achariyar TM, Li B, Peng W, Verghese PB, Shi Y, McConnell E, Benraiss A, Kasper T, Song W, Takana T, Holtzman DM, Nedergaard M, Deane R. "Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation." Molecular neurodegeneration.. 2016 Dec 8; 11(1):74. Epub 2016 Dec 08.
11/4/2016
Bosetti F, Galis ZS, Bynoe MS, Charette M, Cipolla MJ, Del Zoppo GJ, Gould D, Hatsukami TS, Jones TL, Koenig JI, Lutty GA, Maric-Bilkan C, Stevens T, Tolunay HE, Koroshetz W, . ""Small Blood Vessels: Big Health Problems?": Scientific Recommendations of the National Institutes of Health Workshop." Journal of the American Heart Association.. 2016 Nov 4; 5(11)Epub 2016 Nov 04.
9/2016
McConnell ED, Wei HS, Reitz KM, Kang H, Takano T, Vates GE, Nedergaard M. "Cerebral microcirculatory failure after subarachnoid hemorrhage is reversed by hyaluronidase." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2016 Sep; 36(9):1537-52. Epub 2015 Oct 14.
9/2016
Peng W, Achariyar TM, Li B, Liao Y, Mestre H, Hitomi E, Regan S, Kasper T, Peng S, Ding F, Benveniste H, Nedergaard M, Deane R. "Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease." Neurobiology of disease.. 2016 Sep; 93:215-25. Epub 2016 May 24.
8/17/2016
Wei HS, Kang H, Rasheed ID, Zhou S, Lou N, Gershteyn A, McConnell ED, Wang Y, Richardson KE, Palmer AF, Xu C, Wan J, Nedergaard M. "Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation." Neuron.. 2016 Aug 17; 91(4):851-862. Epub 2016 Aug 04.
8/5/2016
Verkhratsky A, Nedergaard M. "The homeostatic astroglia emerges from evolutionary specialization of neural cells." Philosophical transactions of the Royal Society of London. Series B, Biological sciences.. 2016 Aug 5; 371(1700)
7/26/2016
Rasmussen R, Nedergaard M, Petersen NC. "Sulforhodamine 101, a widely used astrocyte marker, can induce cortical seizure-like activity at concentrations commonly used." Scientific reports.. 2016 Jul 26; 6:30433. Epub 2016 Jul 26.
6/7/2016
Benraiss A, Wang S, Herrlinger S, Li X, Chandler-Militello D, Mauceri J, Burm HB, Toner M, Osipovitch M, Jim Xu Q, Ding F, Wang F, Kang N, Kang J, Curtin PC, Brunner D, Windrem MS, Munoz-Sanjuan I, Nedergaard M, Goldman SA. "Human glia can both induce and rescue aspects of disease phenotype in Huntington disease." Nature communications.. 2016 Jun 7; 7:11758. Epub 2016 Jun 07.
6/2016
Kiviniemi V, Wang X, Korhonen V, Keinänen T, Tuovinen T, Autio J, LeVan P, Keilholz S, Zang YF, Hennig J, Nedergaard M. "Ultra-fast magnetic resonance encephalography of physiological brain activity - Glymphatic pulsation mechanisms?" Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2016 Jun; 36(6):1033-45. Epub 2015 Dec 21.
4/29/2016
Ding F, O'Donnell J, Xu Q, Kang N, Goldman N, Nedergaard M. "Changes in the composition of brain interstitial ions control the sleep-wake cycle." Science.. 2016 Apr 29; 352(6285):550-5.
4/2016
Sreetama SC, Takano T, Nedergaard M, Simon SM, Jaiswal JK. "Injured astrocytes are repaired by Synaptotagmin XI-regulated lysosome exocytosis." Cell death and differentiation.. 2016 Apr; 23(4):596-607. Epub 2015 Oct 09.
3/2016
Nedergaard M, Goldman SA. "BRAIN DRAIN." Scientific American.. 2016 Mar; 314(3):44-9.
1/26/2016
Lou N, Takano T, Pei Y, Xavier AL, Goldman SA, Nedergaard M. "Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier." Proceedings of the National Academy of Sciences of the United States of America.. 2016 Jan 26; 113(4):1074-9. Epub 2016 Jan 11.
2016
Staberg M, Michaelsen SR, Olsen LS, Nedergaard MK, Villingshøj M, Stockhausen MT, Hamerlik P, Poulsen HS. "Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro." Cancer cell international.. 2016 16:34. Epub 2016 Apr 26.
2016
Xie L, Kang H, Nedergaard M. "A Novel Model of Transient Occlusion of the Middle Cerebral Artery in Awake Mice." Journal of nature and science.. 2016 2(2)
12/2015
Jessen NA, Munk AS, Lundgaard I, Nedergaard M. "The Glymphatic System: A Beginner's Guide." Neurochemical research.. 2015 Dec; 40(12):2583-99. Epub 2015 May 07.
10/2015
Iliff JJ, Goldman SA, Nedergaard M. "Implications of the discovery of brain lymphatic pathways." The Lancet. Neurology.. 2015 Oct; 14(10):977-9.
9/1/2015
Benveniste H, Hof PR, Nedergaard M, Bechter K. "Modern cerebrospinal fluid flow research and Heinrich Quincke's seminal 1872 article on the distribution of cinnabar in freely moving animals." The Journal of comparative neurology.. 2015 Sep 1; 523(13):2017-8.
9/2015
Liu X, Wang C, Fujita T, Malmstrom HS, Nedergaard M, Ren YF, Dirksen RT. "External Dentin Stimulation Induces ATP Release in Human Teeth." Journal of dental research.. 2015 Sep; 94(9):1259-66. Epub 2015 Jun 30.
9/2015
Makaryus R, Lee H, Feng T, Park JH, Nedergaard M, Jacob Z, Enikolopov G, Benveniste H. "Brain maturation in neonatal rodents is impeded by sevoflurane anesthesia." Anesthesiology.. 2015 Sep; 123(3):557-68.
8/26/2015
Ribeiro Xavier AL, Kress BT, Goldman SA, Lacerda de Menezes JR, Nedergaard M. "A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2015 Aug 26; 35(34):11848-61.
8/15/2015
Benveniste H, Hof PR, Nedergaard M, Bechter K. "Modern cerebrospinal fluid flow research and Heinrich Quincke's seminal 1872 article on the distribution of cinnabar in freely moving animals." The Journal of comparative neurology.. 2015 Aug 15; 523(12):1748-55. Epub 2015 May 12.
8/5/2015
Lee H, Xie L, Yu M, Kang H, Feng T, Deane R, Logan J, Nedergaard M, Benveniste H. "The Effect of Body Posture on Brain Glymphatic Transport." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2015 Aug 5; 35(31):11034-44.
8/2015
Goldman SA, Nedergaard M, Windrem MS. "Modeling cognition and disease using human glial chimeric mice." Glia.. 2015 Aug; 63(8):1483-93. Epub 2015 May 24.
8/2015
Wei HS, Rasheed ID, Takano T, Kang H, Reitz KM, Gershteyn A, Vates GE, Nedergaard M. "156?Capillary-Level Control of Cerebrovascular Tone." Neurosurgery.. 2015 Aug; 62 Suppl 1:216-7.
6/2015
Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, Bain LJ, Bosetti F, Galis ZS, Koroshetz W, Carrillo MC. "Vascular contributions to cognitive impairment and dementia including Alzheimer's disease." Alzheimer's & dementia : the journal of the Alzheimer's Association.. 2015 Jun; 11(6):710-7. Epub 2014 Dec 12.
6/2015
Thrane AS, Rangroo Thrane V, Plog BA, Nedergaard M. "Filtering the muddied waters of brain edema." Trends in neurosciences.. 2015 Jun; 38(6):333-5. Epub 2015 May 22.
5/2015
Plog BA, Nedergaard M. "Why have we not yet developed a simple blood test for TBI?" Expert review of neurotherapeutics.. 2015 May; 15(5):465-8. Epub 2015 Mar 30.
4/23/2015
Lundgaard I, Li B, Xie L, Kang H, Sanggaard S, Haswell JD, Sun W, Goldman S, Blekot S, Nielsen M, Takano T, Deane R, Nedergaard M. "Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism." Nature communications.. 2015 Apr 23; 6:6807. Epub 2015 Apr 23.
3/2015
O'Donnell J, Ding F, Nedergaard M. "Distinct functional states of astrocytes during sleep and wakefulness: Is norepinephrine the master regulator?" Current sleep medicine reports.. 2015 Mar; 1(1):1-8. Epub 2015 Jan 29.
2/21/2015
Ratner V, Zhu L, Kolesov I, Nedergaard M, Benveniste H, Tannenbaum A. "Optimal-mass-transfer-based estimation of glymphatic transport in living brain." Proceedings of SPIE--the International Society for Optical Engineering.. 2015 Feb 21; 9413Epub 2015 Mar 20.
2/2015
Verkhratsky A, Nedergaard M, Hertz L. "Why are astrocytes important?" Neurochemical research.. 2015 Feb; 40(2):389-401. Epub 2014 Aug 12.
1/14/2015
Plog BA, Dashnaw ML, Hitomi E, Peng W, Liao Y, Lou N, Deane R, Nedergaard M. "Biomarkers of traumatic injury are transported from brain to blood via the glymphatic system." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2015 Jan 14; 35(2):518-26.
2015
Nedergaard MK, Michaelsen SR, Urup T, Broholm H, El Ali H, Poulsen HS, Stockhausen MT, Kjaer A, Lassen U. "18F-FET microPET and microMRI for anti-VEGF and anti-PlGF response assessment in an orthotopic murine model of human glioblastoma." PloS one.. 2015 10(2):e0115315. Epub 2015 Feb 13.
2015
Xavier AL, Lima FR, Nedergaard M, Menezes JR. "Ontogeny of CX3CR1-EGFP expressing cells unveil microglia as an integral component of the postnatal subventricular zone." Frontiers in cellular neuroscience.. 2015 9:37. Epub 2015 Feb 17.
12/11/2014
Haydon PG, Nedergaard M. "How do astrocytes participate in neural plasticity?" Cold Spring Harbor perspectives in biology.. 2014 Dec 11; 7(3):a020438. Epub 2014 Dec 11.
12/10/2014
Fujita T, Chen MJ, Li B, Smith NA, Peng W, Sun W, Toner MJ, Kress BT, Wang L, Benraiss A, Takano T, Wang S, Nedergaard M. "Neuronal transgene expression in dominant-negative SNARE mice." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2014 Dec 10; 34(50):16594-604.
12/3/2014
Iliff JJ, Chen MJ, Plog BA, Zeppenfeld DM, Soltero M, Yang L, Singh I, Deane R, Nedergaard M. "Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2014 Dec 3; 34(49):16180-93.
12/2014
Kress BT, Iliff JJ, Xia M, Wang M, Wei H, Zeppenfeld D, Xie L, Kang H, Xu Q, Liew J, Plog BA, Ding F, Deane R, Nedergaard M. "Impairment of paravascular clearance pathways in the aging brain." Annals of neurology.. 2014 Dec; 76(6):845-61. Epub 2014 Sep 26.
11/2014
Thrane AS, Rangroo Thrane V, Nedergaard M. "Drowning stars: reassessing the role of astrocytes in brain edema." Trends in neurosciences.. 2014 Nov; 37(11):620-8. Epub 2014 Sep 15.
10/19/2014
Xavier AL, Menezes JR, Goldman SA, Nedergaard M. "Fine-tuning the central nervous system: microglial modelling of cells and synapses." Philosophical transactions of the Royal Society of London. Series B, Biological sciences.. 2014 Oct 19; 369(1654):20130593.
10/19/2014
Verkhratsky A, Nedergaard M. "Astroglial cradle in the life of the synapse." Philosophical transactions of the Royal Society of London. Series B, Biological sciences.. 2014 Oct 19; 369(1654):20130595.
10/2014
Fields RD, Araque A, Johansen-Berg H, Lim SS, Lynch G, Nave KA, Nedergaard M, Perez R, Sejnowski T, Wake H. "Glial biology in learning and cognition." The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.. 2014 Oct; 20(5):426-31. Epub 2013 Oct 11.
9/25/2014
Cotrina ML, Chen M, Han X, Iliff J, Ren Z, Sun W, Hagemann T, Goldman J, Messing A, Nedergaard M. "Effects of traumatic brain injury on reactive astrogliosis and seizures in mouse models of Alexander disease." Brain research.. 2014 Sep 25; 1582:211-9. Epub 2014 Jul 25.
9/12/2014
Lundgaard I, Osório MJ, Kress B, Sanggaard S, Nedergaard M. "White matter astrocytes in health and disease." Neuroscience.. 2014 Sep 12; 276:161-73. Epub 2013 Nov 11.
8/2014
Chen G, Park CK, Xie RG, Berta T, Nedergaard M, Ji RR. "Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice." Brain : a journal of neurology.. 2014 Aug; 137(Pt 8):2193-209. Epub 2014 Jun 11.
7/1/2014
Petraglia AL, Plog BA, Dayawansa S, Chen M, Dashnaw ML, Czerniecka K, Walker CT, Viterise T, Hyrien O, Iliff JJ, Deane R, Nedergaard M, Huang JH. "The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: a novel mouse model of chronic traumatic encephalopathy." Journal of neurotrauma.. 2014 Jul 1; 31(13):1211-24. Epub 2014 Jun 12.
7/2014
Tong J, Ren Y, Wang X, Dimopoulos VG, Kesler HN, Liu W, He X, Nedergaard M, Huang JH. "Assessment of Nogo-66 receptor 1 function in vivo after spinal cord injury." Neurosurgery.. 2014 Jul; 75(1):51-60.
7/2014
Kristoffersen K, Nedergaard MK, Villingshøj M, Borup R, Broholm H, Kjær A, Poulsen HS, Stockhausen MT. "Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature." Cancer biology & therapy.. 2014 Jul; 15(7):862-77. Epub 2014 Apr 22.
5/30/2014
Plog BA, Moll KM, Kang H, Iliff JJ, Nedergaard M, Vates GE, Dashnaw ML. "A novel technique for morphometric quantification of subarachnoid hemorrhage-induced microglia activation." Journal of neuroscience methods.. 2014 May 30; 229:44-52. Epub 2014 Apr 13.
4/2014
Larsen BR, Assentoft M, Cotrina ML, Hua SZ, Nedergaard M, Kaila K, Voipio J, Macaulay N. "Contributions of the Na?/K?-ATPase, NKCC1, and Kir4.1 to hippocampal K? clearance and volume responses." Glia.. 2014 Apr; 62(4):608-22. Epub 2014 Jan 30.
1/2014
Takano T, He W, Han X, Wang F, Xu Q, Wang X, Oberheim Bush NA, Cruz N, Dienel GA, Nedergaard M. "Rapid manifestation of reactive astrogliosis in acute hippocampal brain slices." Glia.. 2014 Jan; 62(1):78-95. Epub 2013 Nov 06.
2014
Nedergaard MK, Kristoffersen K, Michaelsen SR, Madsen J, Poulsen HS, Stockhausen MT, Lassen U, Kjaer A. "The use of longitudinal 18F-FET MicroPET imaging to evaluate response to irinotecan in orthotopic human glioblastoma multiforme xenografts." PloS one.. 2014 9(2):e100009. Epub 2014 Jun 11.
2014
Petraglia AL, Plog BA, Dayawansa S, Dashnaw ML, Czerniecka K, Walker CT, Chen M, Hyrien O, Iliff JJ, Deane R, Huang JH, Nedergaard M. "The pathophysiology underlying repetitive mild traumatic brain injury in a novel mouse model of chronic traumatic encephalopathy." Surgical neurology international.. 2014 5:184. Epub 2014 Dec 23.
12/2013
Ji RR, Berta T, Nedergaard M. "Glia and pain: is chronic pain a gliopathy?" Pain.. 2013 Dec; 154 Suppl 1:S10-28. Epub 2013 Jun 20.
12/2013
Ding F, O'Donnell J, Thrane AS, Zeppenfeld D, Kang H, Xie L, Wang F, Nedergaard M. "?1-Adrenergic receptors mediate coordinated Ca2+ signaling of cortical astrocytes in awake, behaving mice." Cell calcium.. 2013 Dec; 54(6):387-94. Epub 2013 Sep 24.
12/2013
Thrane VR, Thrane AS, Wang F, Cotrina ML, Smith NA, Chen M, Xu Q, Kang N, Fujita T, Nagelhus EA, Nedergaard M. "Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering." Nature medicine.. 2013 Dec; 19(12):1643-8. Epub 2013 Nov 17.
11/19/2013
Bekar LK, Nedergaard M. "Is potassium a ubiquitous mediator of vasodilation in the central nervous system?" Biophysical journal.. 2013 Nov 19; 105(10):2238-9.
11/13/2013
Iliff JJ, Wang M, Zeppenfeld DM, Venkataraman A, Plog BA, Liao Y, Deane R, Nedergaard M. "Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2013 Nov 13; 33(46):18190-9.
10/30/2013
Wang F, Smith NA, Xu Q, Goldman S, Peng W, Huang JH, Takano T, Nedergaard M. "Photolysis of caged Ca2+ but not receptor-mediated Ca2+ signaling triggers astrocytic glutamate release." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2013 Oct 30; 33(44):17404-12.
10/18/2013
Xie L, Kang H, Xu Q, Chen MJ, Liao Y, Thiyagarajan M, O'Donnell J, Christensen DJ, Nicholson C, Iliff JJ, Takano T, Deane R, Nedergaard M. "Sleep drives metabolite clearance from the adult brain." Science.. 2013 Oct 18; 342(6156):373-7.
9/2013
Langevin H, Fujita T, Bouffard N, Takano T, Koptiuch C, Badger G, Nedergaard M. "Fibroblast cytoskeletal remodeling induced by tissue stretch involves ATP signaling." Journal of cellular physiology.. 2013 Sep; 228(9):1922-6.
8/2013
Langevin HM, Nedergaard M, Howe A. "Cellular control of connective tissue matrix tension." Journal of cellular biochemistry.. 2013 Aug; 114(8):1714-9.
7/2013
Thrane AS, Takano T, Thrane VR, Wang F, Peng W, Ottersen OP, Nedergaard M, Nagelhus EA. "In vivo NADH fluorescence imaging indicates effect of aquaporin-4 deletion on oxygen microdistribution in cortical spreading depression." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2013 Jul; 33(7):996-9. Epub 2013 Apr 24.
6/28/2013
Nedergaard M. "Neuroscience. Garbage truck of the brain." Science.. 2013 Jun 28; 340(6140):1529-30.
6/25/2013
Chen X, Yang J, Kress BT, Tong J, Liu H, Takano T, Zhao Y, Nedergaard M, Ren Z. "Improved axonal regeneration after spinal cord injury in mice with conditional deletion of ephrin B2 under the GFAP promoter." Neuroscience.. 2013 Jun 25; 241:89-99. Epub 2013 Mar 19.
6/6/2013
Benraiss A, Toner MJ, Xu Q, Bruel-Jungerman E, Rogers EH, Wang F, Economides AN, Davidson BL, Kageyama R, Nedergaard M, Goldman SA. "Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease." Cell stem cell.. 2013 Jun 6; 12(6):787-99.
6/2013
Ren Z, Iliff JJ, Yang L, Yang J, Chen X, Chen MJ, Giese RN, Wang B, Shi X, Nedergaard M. "'Hit & Run' model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2013 Jun; 33(6):834-45. Epub 2013 Feb 27.
6/2013
Iliff JJ, Nedergaard M. "Is there a cerebral lymphatic system?" Stroke.. 2013 Jun; 44(6 Suppl 1):S93-5.
5/1/2013
Yang L, Kress BT, Weber HJ, Thiyagarajan M, Wang B, Deane R, Benveniste H, Iliff JJ, Nedergaard M. "Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer." Journal of translational medicine.. 2013 May 1; 11:107. Epub 2013 May 01.
4/2013
Goldman N, Chandler-Militello D, Langevin HM, Nedergaard M, Takano T. "Purine receptor mediated actin cytoskeleton remodeling of human fibroblasts." Cell calcium.. 2013 Apr; 53(4):297-301. Epub 2013 Feb 22.
3/7/2013
Han X, Chen M, Wang F, Windrem M, Wang S, Shanz S, Xu Q, Oberheim NA, Bekar L, Betstadt S, Silva AJ, Takano T, Goldman SA, Nedergaard M. "Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice." Cell stem cell.. 2013 Mar 7; 12(3):342-53.
3/2013
Iliff JJ, Lee H, Yu M, Feng T, Logan J, Nedergaard M, Benveniste H. "Brain-wide pathway for waste clearance captured by contrast-enhanced MRI." The Journal of clinical investigation.. 2013 Mar; 123(3):1299-309. Epub 2013 Feb 22.
2/2013
Iliff JJ, Nedergaard M. "A link between glial Ca2+ signaling and hypoxia in aging?" Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2013 Feb; 33(2):170. Epub 2012 Dec 05.
1/11/2013
Sun W, McConnell E, Pare JF, Xu Q, Chen M, Peng W, Lovatt D, Han X, Smith Y, Nedergaard M. "Glutamate-dependent neuroglial calcium signaling differs between young and adult brain." Science.. 2013 Jan 11; 339(6116):197-200.
2013
Rangroo Thrane V, Thrane AS, Plog BA, Thiyagarajan M, Iliff JJ, Deane R, Nagelhus EA, Nedergaard M. "Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain." Scientific reports.. 2013 3:2582.
2013
Ji RR, Berta T, Nedergaard M. "Glia and pain: Is chronic pain a gliopathy?" Pain.. 2013 154 Suppl 1
12/12/2012
Wang M, Iliff JJ, Liao Y, Chen MJ, Shinseki MS, Venkataraman A, Cheung J, Wang W, Nedergaard M. "Cognitive deficits and delayed neuronal loss in a mouse model of multiple microinfarcts." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2012 Dec 12; 32(50):17948-60.
12/3/2012
Cotrina ML, Nedergaard M. "Brain connexins in demyelinating diseases: therapeutic potential of glial targets." Brain research.. 2012 Dec 3; 1487:61-8. Epub 2012 Jul 10.
12/3/2012
Bennett MV, Garré JM, Orellana JA, Bukauskas FF, Nedergaard M, Sáez JC. "Connexin and pannexin hemichannels in inflammatory responses of glia and neurons." Brain research.. 2012 Dec 3; 1487:3-15. Epub 2012 Sep 10.
12/2012
Bekar LK, Wei HS, Nedergaard M. "The locus coeruleus-norepinephrine network optimizes coupling of cerebral blood volume with oxygen demand." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2012 Dec; 32(12):2135-45. Epub 2012 Aug 08.
12/2012
Enger R, Gundersen GA, Haj-Yasein NN, Eilert-Olsen M, Thoren AE, Vindedal GF, Petersen PH, Skare O, Nedergaard M, Ottersen OP, Nagelhus EA. "Molecular scaffolds underpinning macroglial polarization: an analysis of retinal Müller cells and brain astrocytes in mouse." Glia.. 2012 Dec; 60(12):2018-26. Epub 2012 Sep 17.
12/2012
Takano T, Chen X, Luo F, Fujita T, Ren Z, Goldman N, Zhao Y, Markman JD, Nedergaard M. "Traditional acupuncture triggers a local increase in adenosine in human subjects." The journal of pain.. 2012 Dec; 13(12):1215-23.
11/13/2012
Thrane AS, Thrane VR, Zeppenfeld D, Lou N, Xu Q, Nagelhus EA, Nedergaard M. "General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex." Proceedings of the National Academy of Sciences of the United States of America.. 2012 Nov 13; 109(46):18974-9. Epub 2012 Oct 29.
11/2012
O'Donnell J, Zeppenfeld D, McConnell E, Pena S, Nedergaard M. "Norepinephrine: a neuromodulator that boosts the function of multiple cell types to optimize CNS performance." Neurochemical research.. 2012 Nov; 37(11):2496-512. Epub 2012 Jun 21.
11/2012
Chen MJ, Kress B, Han X, Moll K, Peng W, Ji RR, Nedergaard M. "Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury." Glia.. 2012 Nov; 60(11):1660-70. Epub 2012 Aug 01.
10/26/2012
Goldman SA, Nedergaard M, Windrem MS. "Glial progenitor cell-based treatment and modeling of neurological disease." Science.. 2012 Oct 26; 338(6106):491-5.
9/18/2012
Thrane VR, Thrane AS, Chang J, Alleluia V, Nagelhus EA, Nedergaard M. "Real-time analysis of microglial activation and motility in hepatic and hyperammonemic encephalopathy." Neuroscience.. 2012 Sep 18; 220:247-55. Epub 2012 Jun 21.
8/15/2012
Iliff JJ, Wang M, Liao Y, Plogg BA, Peng W, Gundersen GA, Benveniste H, Vates GE, Deane R, Goldman SA, Nagelhus EA, Nedergaard M. "A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid ?." Science translational medicine.. 2012 Aug 15; 4(147):147ra111.
7/2012
Nedergaard M, Verkhratsky A. "Artifact versus reality--how astrocytes contribute to synaptic events." Glia.. 2012 Jul; 60(7):1013-23. Epub 2012 Jan 06.
5/15/2012
Wang F, Xu Q, Wang W, Takano T, Nedergaard M. "Bergmann glia modulate cerebellar Purkinje cell bistability via Ca2+-dependent K+ uptake." Proceedings of the National Academy of Sciences of the United States of America.. 2012 May 15; 109(20):7911-6. Epub 2012 Apr 30.
4/17/2012
Lovatt D, Xu Q, Liu W, Takano T, Smith NA, Schnermann J, Tieu K, Nedergaard M. "Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity." Proceedings of the National Academy of Sciences of the United States of America.. 2012 Apr 17; 109(16):6265-70. Epub 2012 Mar 15.
4/11/2012
Messing A, Brenner M, Feany MB, Nedergaard M, Goldman JE. "Alexander disease." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2012 Apr 11; 32(15):5017-23.
4/5/2012
Verkhratsky A, Sofroniew MV, Messing A, Delanerolle NC, Rempe D, Rodriguez Arellano JJ, Nedergaard M. "Neurological diseases as primary gliopathies: a reassessment of neurocentrism." ASN neuro.. 2012 Apr 5; 4(3)Epub 2012 Apr 05.
4/3/2012
Wang F, Smith NA, Xu Q, Fujita T, Baba A, Matsuda T, Takano T, Bekar L, Nedergaard M. "Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+." Science signaling.. 2012 Apr 3; 5(218):ra26. Epub 2012 Apr 03.
4/1/2012
Nedergaard MK, Hedegaard CJ, Poulsen HS. "Targeting the epidermal growth factor receptor in solid tumor malignancies." BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy.. 2012 Apr 1; 26(2):83-99.
3/7/2012
Huang C, Han X, Li X, Lam E, Peng W, Lou N, Torres A, Yang M, Garre JM, Tian GF, Bennett MV, Nedergaard M, Takano T. "Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2012 Mar 7; 32(10):3333-8.
1/24/2012
Torres A, Wang F, Xu Q, Fujita T, Dobrowolski R, Willecke K, Takano T, Nedergaard M. "Extracellular Ca²? acts as a mediator of communication from neurons to glia." Science signaling.. 2012 Jan 24; 5(208):ra8. Epub 2012 Jan 24.
1/2012
Fujita T, Williams EK, Jensen TK, Smith NA, Takano T, Tieu K, Nedergaard M. "Cultured astrocytes do not release adenosine during hypoxic conditions." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2012 Jan; 32(1):e1-7. Epub 2011 Oct 12.
1/2012
Christensen DJ, Nedergaard M. "Random access multiphoton (RAMP) microscopy for investigation of cerebral blood flow regulation mechanisms." Proceedings of SPIE--the International Society for Optical Engineering.. 2012 Jan; 8226Epub 2012 Feb 09.
2012
Oberheim NA, Goldman SA, Nedergaard M. "Heterogeneity of astrocytic form and function." Methods in molecular biology.. 2012 814:23-45.
2012
Verkhratsky A, Pankratov Y, Lalo U, Nedergaard M. "P2X receptors in neuroglia." Wiley interdisciplinary reviews. Membrane transport and signaling. 2012 1(2)
9/2011
Christensen DJ, Nedergaard M. "Two-photon in vivo imaging of cells." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2011 Sep; 26(9):1483-9. Epub 2011 Mar 15.
1/11/2011
Thrane AS, Rappold PM, Fujita T, Torres A, Bekar LK, Takano T, Peng W, Wang F, Thrane VR, Enger R, Haj-Yasein NN, Skare O, Holen T, Klungland A, Ottersen OP, Nedergaard M, Nagelhus EA. "Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema." Proceedings of the National Academy of Sciences of the United States of America.. 2011 Jan 11; 108(2):846-51. Epub 2010 Dec 27.
1/2011
Kasischke KA, Lambert EM, Panepento B, Sun A, Gelbard HA, Burgess RW, Foster TH, Nedergaard M. "Two-photon NADH imaging exposes boundaries of oxygen diffusion in cortical vascular supply regions." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2011 Jan; 31(1):68-81. Epub 2010 Sep 22.
11/2010
Hertz L, Lovatt D, Goldman SA, Nedergaard M. "Adrenoceptors in brain: cellular gene expression and effects on astrocytic metabolism and [Ca(2+)]i." Neurochemistry international.. 2010 Nov; 57(4):411-20. Epub 2010 Apr 07.
10/2010
Rempe DA, Nedergaard M. "Targeting glia for treatment of neurological disease." Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics.. 2010 Oct; 7(4):335-7.
10/2010
Kimelberg HK, Nedergaard M. "Functions of astrocytes and their potential as therapeutic targets." Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics.. 2010 Oct; 7(4):338-53.
9/15/2010
Kang J, Kang N, Yu Y, Zhang J, Petersen N, Tian GF, Nedergaard M. "Sulforhodamine 101 induces long-term potentiation of intrinsic excitability and synaptic efficacy in hippocampal CA1 pyramidal neurons." Neuroscience.. 2010 Sep 15; 169(4):1601-9. Epub 2010 Jun 19.
9/2010
Vates GE, Takano T, Zlokovic B, Nedergaard M. "Pericyte constriction after stroke: the jury is still out." Nature medicine.. 2010 Sep; 16(9):959; author reply 960.
7/2010
Goldman N, Chen M, Fujita T, Xu Q, Peng W, Liu W, Jensen TK, Pei Y, Wang F, Han X, Chen JF, Schnermann J, Takano T, Bekar L, Tieu K, Nedergaard M. "Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture." Nature neuroscience.. 2010 Jul; 13(7):883-8. Epub 2010 May 30.
5/2010
Zhang S, Li B, Lovatt D, Xu J, Song D, Goldman SA, Nedergaard M, Hertz L, Peng L. "5-HT2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional 'serotonin-specific reuptake inhibitors'." Neuron glia biology. 2010 May; 6(2):113-25. Epub 2010 Sep 16.
2/2010
Nedergaard M, Rodríguez JJ, Verkhratsky A. "Glial calcium and diseases of the nervous system." Cell calcium.. 2010 Feb; 47(2):140-9. Epub 2009 Dec 31.
2/2010
Nedergaard M, Verkhratsky A. "Calcium dyshomeostasis and pathological calcium signalling in neurological diseases." Cell calcium.. 2010 Feb; 47(2):101-2. Epub 2010 Jan 15.
10/2009
Rempe DA, Takano T, Nedergaard M. "TR(I)Pping towards treatment for ischemia." Nature neuroscience.. 2009 Oct; 12(10):1215-6.
7/28/2009
Peng W, Cotrina ML, Han X, Yu H, Bekar L, Blum L, Takano T, Tian GF, Goldman SA, Nedergaard M. "Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury." Proceedings of the National Academy of Sciences of the United States of America.. 2009 Jul 28; 106(30):12489-93. Epub 2009 Jul 27.
6/2009
Cotrina ML, Nedergaard M. "Physiological and pathological functions of P2X7 receptor in the spinal cord." Purinergic signalling. 2009 Jun; 5(2):223-32. Epub 2009 Feb 11.
3/11/2009
Oberheim NA, Takano T, Han X, He W, Lin JH, Wang F, Xu Q, Wyatt JD, Pilcher W, Ojemann JG, Ransom BR, Goldman SA, Nedergaard M. "Uniquely hominid features of adult human astrocytes." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2009 Mar 11; 29(10):3276-87.
3/2009
Takano T, Oberheim N, Cotrina ML, Nedergaard M. "Astrocytes and ischemic injury." Stroke.. 2009 Mar; 40(3 Suppl):S8-12. Epub 2008 Dec 08.
2/2009
Hedley-Whyte ET, Goldman JE, Nedergaard M, Friedman A, Han X, Schmidt RE, Powers JM. "Hyaline protoplasmic astrocytopathy of neocortex." Journal of neuropathology and experimental neurology.. 2009 Feb; 68(2):136-47.
1/2009
Takano T, Nedergaard M. "Deciphering migraine." The Journal of clinical investigation.. 2009 Jan; 119(1):16-9.
2009
Wang X, Takano T, Nedergaard M. "Astrocytic calcium signaling: mechanism and implications for functional brain imaging." Methods in molecular biology.. 2009 489:93-109.
12/2008
Bekar LK, He W, Nedergaard M. "Locus coeruleus alpha-adrenergic-mediated activation of cortical astrocytes in vivo." Cerebral cortex.. 2008 Dec; 18(12):2789-95. Epub 2008 Mar 27.
12/2008
Cotrina ML, Lin JH, Nedergaard M. "Adhesive properties of connexin hemichannels." Glia.. 2008 Dec; 56(16):1791-8.
6/5/2008
Windrem MS, Schanz SJ, Guo M, Tian GF, Washco V, Stanwood N, Rasband M, Roy NS, Nedergaard M, Havton LA, Wang S, Goldman SA. "Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse." Cell stem cell.. 2008 Jun 5; 2(6):553-65.
5/15/2008
Xu H, Hu F, Sado Y, Ninomiya Y, Borza DB, Ungvari Z, Lagamma EF, Csiszar A, Nedergaard M, Ballabh P. "Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone." Journal of neuroscience research.. 2008 May 15; 86(7):1482-500.
4/30/2008
Kang J, Kang N, Lovatt D, Torres A, Zhao Z, Lin J, Nedergaard M. "Connexin 43 hemichannels are permeable to ATP." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2008 Apr 30; 28(18):4702-11.
3/26/2008
Oberheim NA, Tian GF, Han X, Peng W, Takano T, Ransom B, Nedergaard M. "Loss of astrocytic domain organization in the epileptic brain." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2008 Mar 26; 28(13):3264-76.
1/16/2008
Lin JH, Lou N, Kang N, Takano T, Hu F, Han X, Xu Q, Lovatt D, Torres A, Willecke K, Yang J, Kang J, Nedergaard M. "A central role of connexin 43 in hypoxic preconditioning." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2008 Jan 16; 28(3):681-95.
1/2008
Neuwelt E, Abbott NJ, Abrey L, Banks WA, Blakley B, Davis T, Engelhardt B, Grammas P, Nedergaard M, Nutt J, Pardridge W, Rosenberg GA, Smith Q, Drewes LR. "Strategies to advance translational research into brain barriers." The Lancet. Neurology.. 2008 Jan; 7(1):84-96.
1/2008
Bekar L, Libionka W, Tian GF, Xu Q, Torres A, Wang X, Lovatt D, Williams E, Takano T, Schnermann J, Bakos R, Nedergaard M. "Adenosine is crucial for deep brain stimulation-mediated attenuation of tremor." Nature medicine.. 2008 Jan; 14(1):75-80. Epub 2007 Dec 23.
11/7/2007
Lovatt D, Sonnewald U, Waagepetersen HS, Schousboe A, He W, Lin JH, Han X, Takano T, Wang S, Sim FJ, Goldman SA, Nedergaard M. "The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2007 Nov 7; 27(45):12255-66.
11/2007
Iadecola C, Nedergaard M. "Glial regulation of the cerebral microvasculature." Nature neuroscience.. 2007 Nov; 10(11):1369-76.
10/31/2007
Braun A, Xu H, Hu F, Kocherlakota P, Siegel D, Chander P, Ungvari Z, Csiszar A, Nedergaard M, Ballabh P. "Paucity of pericytes in germinal matrix vasculature of premature infants." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2007 Oct 31; 27(44):12012-24.
8/28/2007
Jaiswal JK, Fix M, Takano T, Nedergaard M, Simon SM. "Resolving vesicle fusion from lysis to monitor calcium-triggered lysosomal exocytosis in astrocytes." Proceedings of the National Academy of Sciences of the United States of America.. 2007 Aug 28; 104(35):14151-6. Epub 2007 Aug 21.
6/2007
Takano T, Tian GF, Peng W, Lou N, Lovatt D, Hansen AJ, Kasischke KA, Nedergaard M. "Cortical spreading depression causes and coincides with tissue hypoxia." Nature neuroscience.. 2007 Jun; 10(6):754-62. Epub 2007 Apr 29.
5/2007
Takano T, Nedergaard M. "DM-nitrophen provides physiologically significant increases of intracellular [Ca2+] in the presence of Mg2+." Cell calcium.. 2007 May; 41(5):503-4. Epub 2006 Oct 19.
4/2007
Ballabh P, Xu H, Hu F, Braun A, Smith K, Rivera A, Lou N, Ungvari Z, Goldman SA, Csiszar A, Nedergaard M. "Angiogenic inhibition reduces germinal matrix hemorrhage." Nature medicine.. 2007 Apr; 13(4):477-85. Epub 2007 Apr 01.
2/1/2007
Lin JH, Takano T, Arcuino G, Wang X, Hu F, Darzynkiewicz Z, Nunes M, Goldman SA, Nedergaard M. "Purinergic signaling regulates neural progenitor cell expansion and neurogenesis." Developmental biology.. 2007 Feb 1; 302(1):356-66. Epub 2006 Sep 16.
2/2007
Takano T, Han X, Deane R, Zlokovic B, Nedergaard M. "Two-photon imaging of astrocytic Ca2+ signaling and the microvasculature in experimental mice models of Alzheimer's disease." Annals of the New York Academy of Sciences.. 2007 Feb; 1097:40-50.
10/2006
Oberheim NA, Wang X, Goldman S, Nedergaard M. "Astrocytic complexity distinguishes the human brain." Trends in neurosciences.. 2006 Oct; 29(10):547-53. Epub 2006 Aug 30.
9/15/2006
Tian GF, Takano T, Lin JH, Wang X, Bekar L, Nedergaard M. "Imaging of cortical astrocytes using 2-photon laser scanning microscopy in the intact mouse brain." Advanced drug delivery reviews.. 2006 Sep 15; 58(7):773-87. Epub 2006 Aug 04.
6/2006
Wang X, Lou N, Xu Q, Tian GF, Peng WG, Han X, Kang J, Takano T, Nedergaard M. "Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo." Nature neuroscience.. 2006 Jun; 9(6):816-23. Epub 2006 May 14.
5/2006
Anderson CM, Nedergaard M. "Emerging challenges of assigning P2X7 receptor function and immunoreactivity in neurons." Trends in neurosciences.. 2006 May; 29(5):257-62. Epub 2006 Mar 27.
5/2006
El-Khoury N, Braun A, Hu F, Pandey M, Nedergaard M, Lagamma EF, Ballabh P. "Astrocyte end-feet in germinal matrix, cerebral cortex, and white matter in developing infants." Pediatric research.. 2006 May; 59(5):673-9.
2/2006
Takano T, Tian GF, Peng W, Lou N, Libionka W, Han X, Nedergaard M. "Astrocyte-mediated control of cerebral blood flow." Nature neuroscience.. 2006 Feb; 9(2):260-7. Epub 2005 Dec 25.
12/2005
Kang N, Xu J, Xu Q, Nedergaard M, Kang J. "Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons." Journal of neurophysiology.. 2005 Dec; 94(6):4121-30. Epub 2005 Sep 14.
12/2005
Singh Roy N, Nakano T, Xuing L, Kang J, Nedergaard M, Goldman SA. "Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells." Experimental neurology.. 2005 Dec; 196(2):224-34. Epub 2005 Sep 29.
11/8/2005
Takano T, Kang J, Jaiswal JK, Simon SM, Lin JH, Yu Y, Li Y, Yang J, Dienel G, Zielke HR, Nedergaard M. "Receptor-mediated glutamate release from volume sensitive channels in astrocytes." Proceedings of the National Academy of Sciences of the United States of America.. 2005 Nov 8; 102(45):16466-71. Epub 2005 Oct 27.
10/2005
Ballabh P, Hu F, Kumarasiri M, Braun A, Nedergaard M. "Development of tight junction molecules in blood vessels of germinal matrix, cerebral cortex, and white matter." Pediatric research.. 2005 Oct; 58(4):791-8.
9/2005
Tian GF, Azmi H, Takano T, Xu Q, Peng W, Lin J, Oberheim N, Lou N, Wang X, Zielke HR, Kang J, Nedergaard M. "An astrocytic basis of epilepsy." Nature medicine.. 2005 Sep; 11(9):973-81. Epub 2005 Aug 14.
6/2005
Nedergaard M, Dirnagl U. "Role of glial cells in cerebral ischemia." Glia.. 2005 Jun; 50(4):281-6.
2/16/2005
Xu J, Kang N, Jiang L, Nedergaard M, Kang J. "Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2005 Feb 16; 25(7):1750-60.
11/2004
Liu QS, Xu Q, Kang J, Nedergaard M. "Astrocyte activation of presynaptic metabotropic glutamate receptors modulates hippocampal inhibitory synaptic transmission." Neuron glia biology. 2004 Nov; 1(4):307-16.
8/2004
Kang N, Jiang L, He W, Xu J, Nedergaard M, Kang J. "Presynaptic inactivation of action potentials and postsynaptic inhibition of GABAA currents contribute to KA-induced disinhibition in CA1 pyramidal neurons." Journal of neurophysiology.. 2004 Aug; 92(2):873-82. Epub 2004 Mar 03.
8/2004
Wang X, Arcuino G, Takano T, Lin J, Peng WG, Wan P, Li P, Xu Q, Liu QS, Goldman SA, Nedergaard M. "P2X7 receptor inhibition improves recovery after spinal cord injury." Nature medicine.. 2004 Aug; 10(8):821-7. Epub 2004 Jul 18.
7/2004
Ballabh P, Braun A, Nedergaard M. "Anatomic analysis of blood vessels in germinal matrix, cerebral cortex, and white matter in developing infants." Pediatric research.. 2004 Jul; 56(1):117-24. Epub 2004 May 05.
6/2004
Ballabh P, Braun A, Nedergaard M. "The blood-brain barrier: an overview: structure, regulation, and clinical implications." Neurobiology of disease.. 2004 Jun; 16(1):1-13.
3/2/2004
Liu QS, Xu Q, Arcuino G, Kang J, Nedergaard M. "Astrocyte-mediated activation of neuronal kainate receptors." Proceedings of the National Academy of Sciences of the United States of America.. 2004 Mar 2; 101(9):3172-7. Epub 2004 Feb 06.
3/2004
Roy NS, Nakano T, Keyoung HM, Windrem M, Rashbaum WK, Alonso ML, Kang J, Peng W, Carpenter MK, Lin J, Nedergaard M, Goldman SA. "Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord." Nature biotechnology.. 2004 Mar; 22(3):297-305. Epub 2004 Feb 15.
2004
Simard M, Nedergaard M. "The neurobiology of glia in the context of water and ion homeostasis." Neuroscience.. 2004 129(4):877-96.
10/8/2003
Simard M, Arcuino G, Takano T, Liu QS, Nedergaard M. "Signaling at the gliovascular interface." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2003 Oct 8; 23(27):9254-62.
10/2003
Ransom B, Behar T, Nedergaard M. "New roles for astrocytes (stars at last)." Trends in neurosciences.. 2003 Oct; 26(10):520-2.
10/2003
Nedergaard M, Ransom B, Goldman SA. "New roles for astrocytes: redefining the functional architecture of the brain." Trends in neurosciences.. 2003 Oct; 26(10):523-30.
7/2003
Anderson CM, Nedergaard M. "Astrocyte-mediated control of cerebral microcirculation." Trends in neurosciences.. 2003 Jul; 26(7):340-4; author reply 344-5.
4/2003
Nunes MC, Roy NS, Keyoung HM, Goodman RR, McKhann G, Jiang L, Kang J, Nedergaard M, Goldman SA. "Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain." Nature medicine.. 2003 Apr; 9(4):439-47. Epub 2003 Mar 10.
1/15/2003
Lin JH, Yang J, Liu S, Takano T, Wang X, Gao Q, Willecke K, Nedergaard M. "Connexin mediates gap junction-independent resistance to cellular injury." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2003 Jan 15; 23(2):430-41.
9/2002
Nedergaard M, Takano T, Hansen AJ. "Beyond the role of glutamate as a neurotransmitter." Nature reviews. Neuroscience.. 2002 Sep; 3(9):748-55.
8/2002
Goldman SA, Nedergaard M. "Erythropoietin strikes a new cord." Nature medicine.. 2002 Aug; 8(8):785-7.
7/23/2002
Arcuino G, Lin JH, Takano T, Liu C, Jiang L, Gao Q, Kang J, Nedergaard M. "Intercellular calcium signaling mediated by point-source burst release of ATP." Proceedings of the National Academy of Sciences of the United States of America.. 2002 Jul 23; 99(15):9840-5. Epub 2002 Jul 03.
6/1/2002
Lin JH, Takano T, Cotrina ML, Arcuino G, Kang J, Liu S, Gao Q, Jiang L, Li F, Lichtenberg-Frate H, Haubrich S, Willecke K, Goldman SA, Nedergaard M. "Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2002 Jun 1; 22(11):4302-11.
1/1/2002
Cotrina ML, Nedergaard M. "Astrocytes in the aging brain." Journal of neuroscience research.. 2002 Jan 1; 67(1):1-10.
9/2001
Takano T, Lin JH, Arcuino G, Gao Q, Yang J, Nedergaard M. "Glutamate release promotes growth of malignant gliomas." Nature medicine.. 2001 Sep; 7(9):1010-5.
5/18/2001
Cotrina ML, Gao Q, Lin JH, Nedergaard M. "Expression and function of astrocytic gap junctions in aging." Brain research.. 2001 May 18; 901(1-2):55-61.
5/2001
Jiang L, Xu J, Nedergaard M, Kang J. "A kainate receptor increases the efficacy of GABAergic synapses." Neuron.. 2001 May; 30(2):503-13.
10/1/2000
Zhang W, Couldwell WT, Song H, Takano T, Lin JH, Nedergaard M. "Tamoxifen-induced enhancement of calcium signaling in glioma and MCF-7 breast cancer cells." Cancer research.. 2000 Oct 1; 60(19):5395-400.
4/15/2000
Cotrina ML, Lin JH, López-García JC, Naus CC, Nedergaard M. "ATP-mediated glia signaling." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2000 Apr 15; 20(8):2835-44.
4/2000
Martins-Ferreira H, Nedergaard M, Nicholson C. "Perspectives on spreading depression." Brain research. Brain research reviews. 2000 Apr; 32(1):215-34.
3/1/2000
Jiang L, Sun S, Nedergaard M, Kang J. "Paired-pulse modulation at individual GABAergic synapses in rat hippocampus." The Journal of physiology.. 2000 Mar 1; 523 Pt 2:425-39.
3/2000
Roy NS, Wang S, Jiang L, Kang J, Benraiss A, Harrison-Restelli C, Fraser RA, Couldwell WT, Kawaguchi A, Okano H, Nedergaard M, Goldman SA. "In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus." Nature medicine.. 2000 Mar; 6(3):271-7.
2/1/2000
Roy NS, Benraiss A, Wang S, Fraser RA, Goodman R, Couldwell WT, Nedergaard M, Kawaguchi A, Okano H, Goldman SA. "Promoter-targeted selection and isolation of neural progenitor cells from the adult human ventricular zone." Journal of neuroscience research.. 2000 Feb 1; 59(3):321-31.
1/2000
Grafstein B, Liu S, Cotrina ML, Goldman SA, Nedergaard M. "Meningeal cells can communicate with astrocytes by calcium signaling." Annals of neurology.. 2000 Jan; 47(1):18-25.
2000
Cotrina, M.; Nedergaard, M. "ATP as a messenger in astrocyte-neuronal communication". The Neuroscientist. 2000; 6(2): 120-126.
10/1999
Simard M, Couldwell WT, Zhang W, Song H, Liu S, Cotrina ML, Goldman S, Nedergaard M. "Glucocorticoids-potent modulators of astrocytic calcium signaling." Glia.. 1999 Oct; 28(1):1-12.
4/15/1999
Zhang W, Couldwell WT, Simard MF, Song H, Lin JH, Nedergaard M. "Direct gap junction communication between malignant glioma cells and astrocytes." Cancer research.. 1999 Apr 15; 59(8):1994-2003.
1/1999
Williams S, Leventhal C, Lemmon V, Nedergaard M, Goldman SA. "Estrogen promotes the initial migration and inception of NgCAM-dependent calcium-signaling by new neurons of the adult songbird brain." Molecular and cellular neurosciences.. 1999 Jan; 13(1):41-55.
12/22/1998
Cotrina ML, Lin JH, Alves-Rodrigues A, Liu S, Li J, Azmi-Ghadimi H, Kang J, Naus CC, Nedergaard M. "Connexins regulate calcium signaling by controlling ATP release." Proceedings of the National Academy of Sciences of the United States of America.. 1998 Dec 22; 95(26):15735-40.
12/1998
Kang J, Jiang L, Goldman SA, Nedergaard M. "Astrocyte-mediated potentiation of inhibitory synaptic transmission." Nature neuroscience.. 1998 Dec; 1(8):683-92.
11/1/1998
Cotrina ML, Lin JH, Nedergaard M. "Cytoskeletal assembly and ATP release regulate astrocytic calcium signaling." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1998 Nov 1; 18(21):8794-804.
10/1998
Lin JH, Weigel H, Cotrina ML, Liu S, Bueno E, Hansen AJ, Hansen TW, Goldman S, Nedergaard M. "Gap-junction-mediated propagation and amplification of cell injury." Nature neuroscience.. 1998 Oct; 1(6):494-500.
5/1998
Pincus DW, Keyoung HM, Harrison-Restelli C, Goodman RR, Fraser RA, Edgar M, Sakakibara S, Okano H, Nedergaard M, Goldman SA. "Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells." Annals of neurology.. 1998 May; 43(5):576-85.
4/1/1998
Cotrina ML, Kang J, Lin JH, Bueno E, Hansen TW, He L, Liu Y, Nedergaard M. "Astrocytic gap junctions remain open during ischemic conditions." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1998 Apr 1; 18(7):2520-37.
4/1998
Pincus DW, Goodman RR, Fraser RA, Nedergaard M, Goldman SA. "Neural stem and progenitor cells: a strategy for gene therapy and brain repair." Neurosurgery.. 1998 Apr; 42(4):858-67; discussion 867-8.
12/19/1997
Goldman SA, Nedergaard M, Crystal RG, Fraser RA, Goodman R, Harrison-Restelli C, Jiang J, Keyoung HM, Leventhal C, Pincus DW, Shahar A, Wang S. "Neural precursors and neuronal production in the adult mammalian forebrain." Annals of the New York Academy of Sciences.. 1997 Dec 19; 835:30-55.
12/1997
Rawanduzy A, Hansen A, Hansen TW, Nedergaard M. "Effective reduction of infarct volume by gap junction blockade in a rodent model of stroke." Journal of neurosurgery.. 1997 Dec; 87(6):916-20.
10/1/1997
Wang Z, Tymianski M, Jones OT, Nedergaard M. "Impact of cytoplasmic calcium buffering on the spatial and temporal characteristics of intercellular calcium signals in astrocytes." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1997 Oct 1; 17(19):7359-71.
5/15/1997
Rawanduzy A, Hansen A, Hansen TW, Nedergaard M. "Effective reduction of infarct volume by gap junction blockade in a rodent model of stroke." Neurosurgical focus.. 1997 May 15; 2(5):E1; discussion 1 p following E1.
1997
Pincus DW, Harrison-Restelli C, Barry J, Goodman RR, Fraser RA, Nedergaard M, Goldman SA. "In vitro neurogenesis by adult human epileptic temporal neocortex." Clinical neurosurgery. 1997 44:17-25.
1/1996
Goldman SA, Williams S, Barami K, Lemmon V, Nedergaard M. "Transient coupling of Ng-CAM expression to NgCAM-dependent calcium signaling during migration of new neurons in the adult songbird brain." Molecular and cellular neurosciences.. 1996 Jan; 7(1):29-45.
1996
Nedergaard M. "Spreading depression as a contributor to ischemic brain damage." Advances in neurology.. 1996 71:75-83; discussion 83-4.
12/1995
Nedergaard M, Cooper AJ, Goldman SA. "Gap junctions are required for the propagation of spreading depression." Journal of neurobiology.. 1995 Dec; 28(4):433-44.
2/1995
Nedergaard M. "Intracellular Ca2+ transients evoked by lactic acid in cultured mammalian neurons." The American journal of physiology.. 1995 Feb; 268(2 Pt 2):R506-13.
5/1994
Makar TK, Nedergaard M, Preuss A, Hertz L, Cooper AJ. "Glutamine transaminase K and omega-amidase activities in primary cultures of astrocytes and neurons and in embryonic chick forebrain: marked induction of brain glutamine transaminase K at time of hatching." Journal of neurochemistry.. 1994 May; 62(5):1983-8.
3/25/1994
Nedergaard M. "Direct signaling from astrocytes to neurons in cultures of mammalian brain cells." Science.. 1994 Mar 25; 263(5154):1768-71.
1/1994
Makar TK, Nedergaard M, Preuss A, Gelbard AS, Perumal AS, Cooper AJ. "Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain." Journal of neurochemistry.. 1994 Jan; 62(1):45-53.
1994
Kirschenbaum,B., Nedergaard,M., Preuss,A., Barami,K., Fraser,R. A., Goldman,S. A. "In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain." Cereb. Cortex. 1994; 4: 576-589.
1994
Kirschenbaum B, Nedergaard M, Preuss A, Barami K, Fraser RA, Goldman SA. "In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain." Cerebral cortex.. 1994 4(6):576-89.
8/1993
Nedergaard M, Goldman SA. "Carrier-mediated transport of lactic acid in cultured neurons and astrocytes." The American journal of physiology.. 1993 Aug; 265(2 Pt 2):R282-9.
7/1993
Nedergaard M, Hansen AJ. "Characterization of cortical depolarizations evoked in focal cerebral ischemia." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 1993 Jul; 13(4):568-74.
8/21/1992
Goldman SA, Nedergaard M. "Newly generated neurons of the adult songbird brain become functionally active in long-term culture." Brain research. Developmental brain research.. 1992 Aug 21; 68(2):217-23.
8/1991
Nedergaard M, Goldman SA, Desai S, Pulsinelli WA. "Acid-induced death in neurons and glia." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1991 Aug; 11(8):2489-97.
3/1991
Nedergaard M, Kraig RP, Tanabe J, Pulsinelli WA. "Dynamics of interstitial and intracellular pH in evolving brain infarct." The American journal of physiology.. 1991 Mar; 260(3 Pt 2):R581-8.
5/15/1990
Nedergaard M, Desai S, Pulsinelli W. "Dicarboxy-dichlorofluorescein: a new fluorescent probe for measuring acidic intracellular pH." Analytical biochemistry.. 1990 May 15; 187(1):109-14.
4/1990
Jakobsen J, Nedergaard M, Aarslew-Jensen M, Diemer NH. "Regional brain glucose metabolism and blood flow in streptozocin-induced diabetic rats." Diabetes.. 1990 Apr; 39(4):437-40.
10/1988
Nedergaard M, Diemer NH. "Experimental cerebral ischemia: barbiturate resistant increase in regional glucose utilization." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 1988 Oct; 8(5):763-6.
5/24/1988
Nedergaard M, Hansen AJ. "Spreading depression is not associated with neuronal injury in the normal brain." Brain research.. 1988 May 24; 449(1-2):395-8.
3/1988
Sillesen H, Nedergaard M, Schroeder T, Buchardt Hansen HJ. "Middle cerebral artery occlusion in presence of low perfusion pressure increases infarct size in rats." Neurological research.. 1988 Mar; 10(1):61-3.
2/1988
Nedergaard M. "Mechanisms of brain damage in focal cerebral ischemia." Acta neurologica Scandinavica.. 1988 Feb; 77(2):81-101.
2/1988
Nedergaard M, Jakobsen J, Diemer NH. "Autoradiographic determination of cerebral glucose content, blood flow, and glucose utilization in focal ischemia of the rat brain: influence of the plasma glucose concentration." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 1988 Feb; 8(1):100-8.
1988
Hansen AJ, Nedergaard M. "Brain ion homeostasis in cerebral ischemia." Neurochemical pathology. 1988 9:195-209.
12/1987
Nedergaard M, Gjedde A, Diemer NH. "Hyperglycaemia protects against neuronal injury around experimental brain infarcts." Neurological research.. 1987 Dec; 9(4):241-4.
4/7/1987
Nedergaard M. "Transient focal ischemia in hyperglycemic rats is associated with increased cerebral infarction." Brain research.. 1987 Apr 7; 408(1-2):79-85.
1987
Nedergaard M, Diemer NH. "Focal ischemia of the rat brain, with special reference to the influence of plasma glucose concentration." Acta neuropathologica.. 1987 73(2):131-7.
1987
Nedergaard M. "Neuronal injury in the infarct border: a neuropathological study in the rat." Acta neuropathologica.. 1987 73(3):267-74.
10/1986
Nedergaard M, Astrup J. "Infarct rim: effect of hyperglycemia on direct current potential and [14C]2-deoxyglucose phosphorylation." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 1986 Oct; 6(5):607-15.
8/1986
Nedergaard M, Gjedde A, Diemer NH. "Focal ischemia of the rat brain: autoradiographic determination of cerebral glucose utilization, glucose content, and blood flow." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 1986 Aug; 6(4):414-24.
1986
Nedergaard M, Vorstrup S, Astrup J. "Cell density in the border zone around old small human brain infarcts." Stroke.. 1986 17(6):1129-37.
5/1983
Nedergaard M, Egeberg J, Kromann H. "Irradiation protects against pancreatic islet degeneration and hyperglycaemia following streptozotocin treatment of mice." Diabetologia.. 1983 May; 24(5):382-6.
1983
Nedergaard M, Klinken L, Paulson OB. "Secondary brain stem hemorrhage in stroke." Stroke.. 1983 14(4):501-5.
3/1982
Kromann H, Christy M, Lernmark A, Nedergaard M, Nerup J. "The low dose streptozotocin murine model of type 1 (insulin-dependent) diabetes mellitus: studies in vivo and in vitro of the modulating effect of sex hormones." Diabetologia.. 1982 Mar; 22(3):194-8.