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AnnaLynn M. Williams, Ph.D.

AnnaLynn M. Williams, Ph.D.

Contact

Call Center (585) 276-3000

About Me

Faculty Appointments

Assistant Professor - Department of Surgery, Cancer Control (SMD)

Assistant Professor - Cancer Center - Joint

Assistant Professor - Department of Public Health Sciences (SMD) - Joint

Credentials

Post-doctoral Training & Residency

Training Program in Pediatric Cancer Survivorship Research, Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital 2019 - 2022

Education

PhD | University of Rochester School of Medicine & Dentistry. Epidemiology. 2019

MS | University at Buffalo, The State University of New York. Epidemiology. 2013

BA | University of Rochester. Biological Science. 2008

Research

Dr. Williams’ research focuses on cancer-related neuropsychological and psychosocial sequelae, their underlying mechanisms, and effective interventions in adolescent and young adult cancer survivors. She is particularly interested in accelerated physiologic and biologic aging as an underlying molecu...
Dr. Williams’ research focuses on cancer-related neuropsychological and psychosocial sequelae, their underlying mechanisms, and effective interventions in adolescent and young adult cancer survivors. She is particularly interested in accelerated physiologic and biologic aging as an underlying molecular mechanism by which cancer-related sequelae arise and in exploiting those pathways to identify potential interventions among high-risk subgroups.

AnnaLynn_Williams@urmc.rochester.edu

Publications

Journal Articles

Hypogonadism and Neurocognitive Outcomes among Childhood Cancer Survivors.

Yoshida T, Alexander T, Xing M, Mirzaei S S, Williams AM, Lubas M, Brinkman TM, Chemaitilly W, Robison LL, Hudson MM, Krull KR, Delaney A

European journal of endocrinology. 2024 March 12 Epub 03/12/2024.

Defining Practice Capacity for Cancer Care Delivery to Adolescents and Young Adults in the Community Setting: 2022 Landscape Assessment Results.

Beauchemin MP, Ji L, Williams AM, Nightingale CL, Dressler EV, Salsman JM, Santacroce SJ, Freyer DR, Roth ME, Parsons SK

Journal of adolescent and young adult oncology.. 2024 February 23 Epub 02/23/2024.

Systemic Biological Mechanisms of Neurocognitive Dysfunction in Long-term Survivors of Childhood Hodgkin Lymphoma.

Williams AM, Liu W, Ehrhardt MJ, Mirzaei Salehabadi S, Panoskaltsis-Mortari A, Phillips NS, Mulrooney DA, Flerlage JE, Yasui Y, Srivastava DK, Robison LL, Hudson MM, Ness KK, Sabin ND, Krull KR

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2024 February 21 Epub 02/21/2024.

Plant Foods Intake and Risk of Premature Aging in Adult Survivors of Childhood Cancer in the St Jude Lifetime Cohort (SJLIFE).

Wang M, Lan T, Williams AM, Ehrhardt MJ, Lanctot JQ, Jiang S, Krull KR, Armstrong GT, Hudson MM, Colditz GA, Robison LL, Ness KK, Park Y

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2024 January 23 :JCO2301260. Epub 01/23/2024.

Exercise and inflammatory cytokine regulation among older adults with myeloid malignancies.

Loh KP, Wang Y, Sanapala C, Gilmore N, Netherby-Winslow C, Mendler JH, Liesveld J, Huselton E, Williams AM, Klepin HD, Jensen-Battaglia M, Mustian K, Vertino P, Susiarjo M, Janelsins MC

Experimental gerontology.. 2024 January 22 :112364. Epub 01/22/2024.

Psychological Outcomes in Adolescent and Young Adult Cancer Survivors.

McGrady ME, Willard VW, Williams AM, Brinkman TM

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2023 November 15 :JCO2301465. Epub 11/15/2023.

PENTEC: Biodevelopmental Considerations in Pediatric Patients With Cancer and Childhood Cancer Survivors.

Bates JE, Marples B, Hudson MM, Williams AM, Marcus K, Howell R, Paulino A, Constine LS

International journal of radiation oncology, biology, physics.. 2023 November 14 Epub 11/14/2023.

Deficit Accumulation Index and Biological Markers of Aging in Survivors of Childhood Cancer.

Williams AM, Mandelblatt JS, Wang M, Dong Q, Armstrong GT, Bhakta N, Brinkman TM, Ehrhardt MJ, Mulrooney DA, Gilmore N, Robison LL, Yasui Y, Small BJ, Srivastava D, Hudson MM, Ness KK, Krull KR, Wang Z

JAMA network open.. 2023 November 16 (11):e2344015. Epub 11/01/2023.

Neurocognitive Impairment Associated with Chronic Morbidity in Long-term Survivors of Hodgkin Lymphoma.

Phillips NS, Mulrooney DA, Williams AM, Liu W, Khan RB, Ehrhardt M, Folse T, Krasin MJ, Srivastava DKS, Ness KK, Hudson MM, Sabin ND, Krull KR

Blood advances.. 2023 September 20 Epub 09/20/2023.

Exercise and epigenetic ages in older adults with myeloid malignancies.

Loh KP, Sanapala C, Jensen-Battaglia M, Rana A, Sohn MB, Watson E, Gilmore N, Klepin HD, Mendler JH, Liesveld J, Huselton E, LoCastro M, Susiarjo M, Netherby-Winslow C, Williams AM, Mustian K, Vertino P, Janelsins MC

European journal of medical research.. 2023 May 3028 (1):180. Epub 05/30/2023.

Late-onset Cognitive Impairment and Modifiable Risk Factors in Adult Childhood Cancer Survivors.

Phillips NS, Stratton KL, Williams AM, Ahles T, Ness KK, Cohen HJ, Edelstein K, Yasui Y, Oeffinger K, Chow EJ, Howell RM, Robison LL, Armstrong GT, Leisenring WM, Krull KR

JAMA network open.. 2023 May 16 (5):e2316077. Epub 05/01/2023.

The role of splenectomy in management of splenic B-cell lymphomas.

Archibald WJ, Baran AM, Williams AM, Salloum RM, Richard Burack W, Evans AG, Syposs CR, Zent CS

Leukemia research.. 2023 March 2128 :107053. Epub 03/02/2023.

Premature Aging as an Accumulation of Deficits in Young Adult Survivors of Pediatric Cancer.

Williams AM, Mandelblatt J, Wang M, Armstrong GT, Bhakta N, Brinkman TM, Chemaitilly W, Ehrhardt MJ, Mulrooney DA, Small BJ, Wang Z, Srivastava D, Robison LL, Hudson MM, Ness KK, Krull KR

Journal of the National Cancer Institute.. 2022 November 12 Epub 11/12/2022.

The association between cancer-related fatigue and diabetes from pre-chemotherapy to 6 months post-chemotherapy.

Kleckner AS, Kleckner IR, Culakova E, Shayne M, Belcher EK, Gudina AT, Williams AM, Onitilo AA, Hopkins JO, Gross H, Mustian KM, Peppone LJ, Janelsins MC

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.. 2022 June 9 Epub 06/09/2022.

Modifiable Risk Factors for Neurocognitive and Psychosocial Problems After Hodgkin Lymphoma.

Williams AM, Mirzaei Salehabadi S, Xing M, Phillips NS, Ehrhardt M, Howell R, Yasui Y, Oeffinger K, Gibson TM, Chow EJ, Leisenring WM, Srivastava DS, Hudson MM, Robison LL, Armstrong G, Krull KR

Blood.. 2021 December 3 Epub 12/03/2021.

Physiologic Frailty and Neurocognitive Decline Among Young-Adult Childhood Cancer Survivors: A Prospective Study From the St Jude Lifetime Cohort.

Williams AM, Krull KR, Howell CR, Banerjee P, Brinkman TM, Kaste SC, Partin RE, Srivastava D, Yasui Y, Armstrong GT, Robison LL, Hudson MM, Ness KK

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2021 November 139 (31):3485-3495. Epub 07/20/2021.

Rethinking Success in Pediatric Oncology: Beyond 5-Year Survival.

Williams AM, Liu Q, Bhakta N, Krull KR, Hudson MM, Robison LL, Yasui Y

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2021 July 1039 (20):2227-2231. Epub 03/26/2021.

Biomarkers of Cognitive Impairment in Pediatric Cancer Survivors.

Williams AM, Cole PD

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2021 June 139 (16):1766-1774. Epub 04/22/2021.

Cumulative burden of chronic health conditions among adolescent and young adult survivors of childhood cancer: Identification of vulnerable groups at key medical transitions.

Ehrhardt MJ, Williams AM, Liu Q, Hudson Scholle S, Bhakta N, Yasui Y, Robison LL, Hudson MM

Pediatric blood & cancer.. 2021 June 68 (6):e29030. Epub 03/31/2021.

Childhood Neurotoxicity and Brain Resilience to Adverse Events during Adulthood.

Williams AM, Cheung YT, Hyun G, Liu W, Ness KK, Ehrhardt MJ, Mulrooney DA, Bhakta N, Banerjee P, Brinkman TM, Green DM, Chemaitilly W, Huang IC, Srivastava D, Hudson MM, Robison LL, Krull KR

Annals of neurology.. 2021 March 89 (3):534-545. Epub 12/31/2020.

Fatigue, anxiety, and quality of life in breast cancer patients compared to non-cancer controls: a nationwide longitudinal analysis.

Williams AM, Khan CP, Heckler CE, Barton DL, Ontko M, Geer J, Kleckner AS, Dakhil S, Mitchell J, Mustian KM, Peppone LJ, Kipnis V, Kamen CS, O'Mara AM, Janelsins MC

Breast cancer research and treatment.. 2021 January 4 Epub 01/04/2021.

Toxicity patterns of novel PI3K combinations in patients with non-Hodgkin lymphoma.

Rodgers TD, Williams AM, Baran A, Reagan PM, Casulo C, Zent CS, Evans A, Friedberg JW, Barr PM

Leukemia & lymphoma.. 2020 October 25 :1-8. Epub 10/25/2020.

Additional B-cell malignancies in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL).

Meacham PJ, Williams AM, Strawderman M, Baran AM, Archibald WJ, Wallace DS, Tschernia NP, Burack WR, Barr PM, Zent CS

Leukemia & lymphoma.. 2020 March 16 :1-9. Epub 03/16/2020.

Cognitive function in patients with chronic lymphocytic leukemia: a cross-sectional study examining effects of disease and treatment.

Williams AM, van Wijngaarden E, Seplaki CL, Heckler CE, Weber MT, Barr PM, Zent CS, Janelsins MC

Leukemia & lymphoma.. 2020 March 9 :1-9. Epub 03/09/2020.

Impact of Respiratory Developmental Stage on Sensitivity to Late Effects of Radiation in Pediatric Cancer Survivors.

Khan F, Williams AM, Weiner DJ, Constine LS

Advances in radiation oncology.. 2020 5 (3):426-433. Epub 12/11/2019.

Efficacy of lenalidomide in high-risk diffuse large B-cell lymphoma.

Rodgers TD, Baran A, Reagan PM, Casulo C, Zent C, Evans A, Burack R, Williams AM, Friedberg JW, Barr PM

British journal of haematology.. 2019 December 17 Epub 12/17/2019.

Significant weight gain in CLL patients treated with Ibrutinib: A potentially deleterious consequence of therapy.

Williams AM, Baran AM, Schaffer M, Bushart J, Rich L, Moore J, Barr PM, Zent CS

American journal of hematology.. 2019 October 17 Epub 10/17/2019.

Tumor Lysis, Adverse Events, and Dose Adjustments in 297 Venetoclax-Treated CLL Patients in Routine Clinical Practice.

Roeker LE, Fox CP, Eyre TA, Brander DM, Allan JN, Schuster SJ, Nabhan C, Hill BT, Shah NN, Lansigan F, Yazdy M, Cheson BD, Lamanna N, Singavi AK, Coombs CC, Barr PM, Skarbnik AP, Shadman M, Ujjani CS, Tuncer HH, Winter AM, Rhodes J, Dorsey C, Morse H, Kabel C, Pagel JM, Williams AM, Jacobs R, Goy A, Muralikrishnan S, Pearson L, Sitlinger A, Bailey N, Schuh A, Kirkwood AA, Mato AR

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2019 July 1525 (14):4264-4270. Epub 04/19/2019.

A retrospective comparison of venetoclax alone or in combination with an anti-CD20 monoclonal antibody in R/R CLL.

Mato AR, Roeker LE, Eyre TA, Nabhan C, Lamanna N, Hill BT, Brander DM, Barr PM, Lansigan F, Cheson BD, Singavi AK, Yazdy MS, Shah NN, Allan JN, Bhavsar EB, Rhodes J, Kennard K, Schuster SJ, Williams AM, Skarbnik AP, Goy AH, Goodfriend JM, Dorsey C, Coombs CC, Tuncer H, Ujjani CS, Jacobs R, Winter AM, Pagel JM, Bailey N, Schuh A, Shadman M, Sitlinger A, Weissbrot H, Muralikrishnan S, Zelenetz A, Kirkwood AA, Fox CP

Blood advances.. 2019 May 283 (10):1568-1573. Epub 1900 01 01.

Ibrutinib Dose Adherence and Therapeutic Efficacy in Non-Hodgkin Lymphoma: A Single-Center Experience.

Williams AM, Baran AM, Casulo C, Reagan P, Friedberg JW, Helber M, Moore J, Baloga E, Zent CS, Barr PM

Clinical lymphoma, myeloma & leukemia.. 2018 October 13 Epub 10/13/2018.

Longitudinal Trajectory and Characterization of Cancer-Related Cognitive Impairment in a Nationwide Cohort Study.

Janelsins MC, Heckler CE, Peppone LJ, Ahles TA, Mohile SG, Mustian KM, Palesh O, O'Mara AM, Minasian LM, Williams AM, Magnuson A, Geer J, Dakhil SR, Hopkins JO, Morrow GR

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2018 September 21 :JCO2018786624. Epub 09/21/2018.

Real-world outcomes and management strategies for venetoclax-treated chronic lymphocytic leukemia patients in the United States.

Mato AR, Thompson M, Allan JN, Brander DM, Pagel JM, Ujjani CS, Hill BT, Lamanna N, Lansigan F, Jacobs R, Shadman M, Skarbnik AP, Pu JJ, Barr PM, Sehgal AR, Cheson BD, Zent CS, Tuncer HH, Schuster SJ, Pickens PV, Shah NN, Goy A, Winter AM, Garcia C, Kennard K, Isaac K, Dorsey C, Gashonia LM, Singavi AK, Roeker LE, Zelenetz A, Williams A, Howlett C, Weissbrot H, Ali N, Khajavian S, Sitlinger A, Tranchito E, Rhodes J, Felsenfeld J, Bailey N, Patel B, Burns TF, Yacur M, Malhotra M, Svoboda J, Furman RR, Nabhan C

Haematologica.. 2018 September 103 (9):1511-1517. Epub 06/07/2018.

Predicting Cardiovascular Disease Among Testicular Cancer Survivors After Modern Cisplatin-based Chemotherapy: Application of the Framingham Risk Score.

Feldman DR, Ardeshir-Rouhani-Fard S, Monahan P, Sesso HD, Fung C, Williams AM, Hamilton RJ, Vaughn DJ, Beard CJ, Cook R, Zaid MA, Lipshultz SE, Einhorn LH, Oeffinger KC, Travis LB, Fossa SD,

Clinical genitourinary cancer.. 2018 August 16 (4):e761-e769. Epub 02/05/2018.

Management of melanoma in patients with chronic lymphocytic leukemia.

Archibald WJ, Meacham PJ, Williams AM, Baran AM, Victor AI, Barr PM, Sahasrahbudhe DM, Zent CS

Leukemia research.. 2018 August 71 :43-46. Epub 07/06/2018.

Cumulative Burden of Morbidity Among Testicular Cancer Survivors After Standard Cisplatin-Based Chemotherapy: A Multi-Institutional Study.

Kerns SL, Fung C, Monahan PO, Ardeshir-Rouhani-Fard S, Abu Zaid MI, Williams AM, Stump TE, Sesso HD, Feldman DR, Hamilton RJ, Vaughn DJ, Beard C, Huddart RA, Kim J, Kollmannsberger C, Sahasrabudhe DM, Cook R, Fossa SD, Einhorn LH, Travis LB,

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2018 May 2036 (15):1505-1512. Epub 04/04/2018.

Analysis of the risk of infection in patients with chronic lymphocytic leukemia in the era of novel therapies.

Williams AM, Baran AM, Meacham PJ, Feldman MM, Valencia HE, Newsom-Stewart C, Gupta N, Janelsins MC, Barr PM, Zent CS

Leukemia & lymphoma.. 2018 March 59 (3):625-632. Epub 07/11/2017.

Clinical and Genetic Risk Factors for Adverse Metabolic Outcomes in North American Testicular Cancer Survivors.

Zaid MA, Gathirua-Mwangi WG, Fung C, Monahan PO, El-Charif O, Williams AM, Feldman DR, Hamilton RJ, Vaughn DJ, Beard CJ, Cook R, Althouse SK, Ardeshir-Rouhani-Fard S, Dinh PC, Sesso HD, Einhorn LH, Fossa SD, Travis LB,

Journal of the National Comprehensive Cancer Network : JNCCN.. 2018 March 16 (3):257-265. Epub 1900 01 01.

Associations between inflammatory markers and cognitive function in breast cancer patients receiving chemotherapy.

Williams AM, Shah R, Shayne M, Huston AJ, Krebs M, Murray N, Thompson BD, Doyle K, Korotkin J, van Wijngaarden E, Hyland S, Moynihan JA, Cory-Slechta DA, Janelsins MC

Journal of neuroimmunology.. 2018 January 15314 :17-23. Epub 10/18/2017.

Ibrutinib therapy for lymphoplasmacytic lymphoma.

Helber MJ, Moore JE, Williams AM, Meacham PJ, Rothberg PG, Zent CS

American journal of hematology.. 2017 September 92 (9):E542-E544. Epub 06/09/2017.

Multi-Institutional Assessment of Adverse Health Outcomes Among North American Testicular Cancer Survivors After Modern Cisplatin-Based Chemotherapy.

Fung C, Sesso HD, Williams AM, Kerns SL, Monahan P, Abu Zaid M, Feldman DR, Hamilton RJ, Vaughn DJ, Beard CJ, Kollmannsberger CK, Cook R, Althouse S, Ardeshir-Rouhani-Fard S, Lipshultz SE, Einhorn LH, Fossa SD, Travis LB,

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2017 April 1035 (11):1211-1222. Epub 02/27/2017.

What is known and unknown about chemotherapy-related cognitive impairment in patients with haematological malignancies and areas of needed research.

Williams AM, Zent CS, Janelsins MC

British journal of haematology.. 2016 September 174 (6):835-46. Epub 07/08/2016.

Cognitive function in cancer survivors: analysis of the 1999-2002 National Health and Nutrition Examination Survey.

Williams AM, Janelsins MC, van Wijngaarden E

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.. 2016 May 24 (5):2155-2162. Epub 11/09/2015.

Long-term Morbidity of Testicular Cancer Treatment.

Fung C, Fossa SD, Williams A, Travis LB

The Urologic clinics of North America.. 2015 August 42 (3):393-408. Epub 06/10/2015.

Dietary lignan intake and androgen receptor expression in breast tumors.

Williams AM, Bonner M, Ochs-Balcom HM, Hwang H, Morrison C, McCann SE

Cancer causes & control : CCC.. 2015 February 26 (2):311-317. Epub 12/04/2014.

Association between metabolic syndrome and periodontal disease measures in postmenopausal women: the Buffalo OsteoPerio study.

LaMonte MJ, Williams AM, Genco RJ, Andrews CA, Hovey KM, Millen AE, Browne RW, Trevisan M, Wactawski-Wende J

Journal of periodontology.. 2014 November 85 (11):1489-501. Epub 05/26/2014.