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Alayna E. Loiselle, Ph.D.

Publications

Showing all 25 journal articles & 0 books available

Journal Articles

6/15/2018
Studentsova V, Mora KM, Glasner MF, Buckley MR, Loiselle AE. "Obesity/Type II Diabetes Promotes Function-limiting Changes in Murine Tendons that are not reversed by Restoring Normal Metabolic Function." Scientific reports.. 2018 Jun 15; 8(1):9218. Epub 2018 Jun 15.

12/2017
Ackerman JE, Bah I, Jonason JH, Buckley MR, Loiselle AE. "Aging does not alter tendon mechanical properties during homeostasis, but does impair flexor tendon healing." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2017 Dec 0; 35(12):2716-2724. Epub 2017 May 03.

8/17/2017
Ackerman JE, Best KT, O'Keefe RJ, Loiselle AE. "Deletion of EP4 in S100a4-lineage cells reduces scar tissue formation during early but not later stages of tendon healing." Scientific reports.. 2017 Aug 17; 7(1):8658. Epub 2017 Aug 17.

2017
Ackerman JE, Geary MB, Orner CA, Bawany F, Loiselle AE. "Obesity/Type II diabetes alters macrophage polarization resulting in a fibrotic tendon healing response." PloS one.. 2017 12(7):e0181127. Epub 2017 Jul 07.

9/19/2016
Ackerman JE, Loiselle AE. "Murine Flexor Tendon Injury and Repair Surgery." Journal of visualized experiments : JoVE.. 2016 Sep 19; (115)Epub 2016 Sep 19.

3/2016
Orner CA, Geary MB, Hammert WC, O'Keefe RJ, Loiselle AE. "Low-Dose and Short-Duration Matrix Metalloproteinase 9 Inhibition Does Not Affect Adhesion Formation during Murine Flexor Tendon Healing." Plastic and reconstructive surgery.. 2016 Mar 0; 137(3):545e-553e.

1/2016
Loiselle AE, Kelly M, Hammert WC. "Biological Augmentation of Flexor Tendon Repair: A Challenging Cellular Landscape." The Journal of hand surgery.. 2016 Jan 0; 41(1):144-9; quiz 149. Epub 2015 Dec 01.

6/2015
Loiselle AE, Yukata K, Geary MB, Kondabolu S, Shi S, Jonason JH, Awad HA, O'Keefe RJ. "Development of antisense oligonucleotide (ASO) technology against Tgf-? signaling to prevent scarring during flexor tendon repair." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2015 Jun 0; 33(6):859-66.

3/2015
Zhang M, Feigenson M, Sheu TJ, Awad HA, Schwarz EM, Jonason JH, Loiselle AE, O'Keefe RJ. "Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength." Bone.. 2015 Mar 0; 72:92-100. Epub 2014 Nov 29.

1/2015
Lee DJ, Southgate RD, Farhat YM, Loiselle AE, Hammert WC, Awad HA, O'Keefe RJ. "Parathyroid hormone 1-34 enhances extracellular matrix deposition and organization during flexor tendon repair." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2015 Jan 0; 33(1):17-24. Epub 2014 Sep 29.

6/3/2014
Govey PM, Jacobs JM, Tilton SC, Loiselle AE, Zhang Y, Freeman WM, Waters KM, Karin NJ, Donahue HJ. "Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways." Journal of biomechanics.. 2014 Jun 3; 47(8):1838-45. Epub 2014 Mar 25.

4/9/2014
Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ. "Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysis." BMC musculoskeletal disorders. 2014 Apr 9; 15:122. Epub 2014 Apr 09.

2/2014
Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ. "Shifting paradigms on the role of connexin43 in the skeletal response to mechanical load." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2014 Feb 0; 29(2):275-86.

11/2013
Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ. "Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling." Bone.. 2013 Nov 0; 57(1):76-83. Epub 2013 Jul 24.

8/2013
Loiselle AE, Wei L, Faryad M, Paul EM, Lewis GS, Gao J, Lakhtakia A, Donahue HJ. "Specific biomimetic hydroxyapatite nanotopographies enhance osteoblastic differentiation and bone graft osteointegration." Tissue engineering. Part A.. 2013 Aug 0; 19(15-16):1704-12. Epub 2013 Apr 25.

6/2013
Loiselle AE, Jiang JX, Donahue HJ. "Gap junction and hemichannel functions in osteocytes." Bone.. 2013 Jun 0; 54(2):205-12. Epub 2012 Oct 13.

6/2013
Govey PM, Loiselle AE, Donahue HJ. "Biophysical regulation of stem cell differentiation." Current osteoporosis reports.. 2013 Jun 0; 11(2):83-91.

1/2013
Loiselle AE, Paul EM, Lewis GS, Donahue HJ. "Osteoblast and osteocyte-specific loss of Connexin43 results in delayed bone formation and healing during murine fracture healing." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2013 Jan 0; 31(1):147-54. Epub 2012 Jun 20.

2013
Loiselle AE, Lloyd SA, Paul EM, Lewis GS, Donahue HJ. "Inhibition of GSK-3? rescues the impairments in bone formation and mechanical properties associated with fracture healing in osteoblast selective connexin 43 deficient mice." PloS one.. 2013 8(11):e81399. Epub 2013 Nov 08.

2012
Loiselle AE, Frisch BJ, Wolenski M, Jacobson JA, Calvi LM, Schwarz EM, Awad HA, O'Keefe RJ. "Bone marrow-derived matrix metalloproteinase-9 is associated with fibrous adhesion formation after murine flexor tendon injury." PloS one.. 2012 7(7):e40602. Epub 2012 Jul 11.

11/2011
Lim JY, Loiselle AE, Lee JS, Zhang Y, Salvi JD, Donahue HJ. "Optimizing the osteogenic potential of adult stem cells for skeletal regeneration." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2011 Nov 0; 29(11):1627-33. Epub 2011 Apr 20.

5/2011
Katzel EB, Wolenski M, Loiselle AE, Basile P, Flick LM, Langstein HN, Hilton MJ, Awad HA, Hammert WC, O'Keefe RJ. "Impact of Smad3 loss of function on scarring and adhesion formation during tendon healing." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2011 May 0; 29(5):684-93. Epub 2010 Sep 14.

8/2010
Gunnell LM, Jonason JH, Loiselle AE, Kohn A, Schwarz EM, Hilton MJ, O'Keefe RJ. "TAK1 regulates cartilage and joint development via the MAPK and BMP signaling pathways." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2010 Aug 0; 25(8):1784-97.

8/2009
Xie C, Liang B, Xue M, Lin AS, Loiselle A, Schwarz EM, Guldberg RE, O'Keefe RJ, Zhang X. "Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4." The American journal of pathology.. 2009 Aug 0; 175(2):772-85. Epub 2009 Jul 23.

6/2009
Loiselle AE, Bragdon GA, Jacobson JA, Hasslund S, Cortes ZE, Schwarz EM, Mitten DJ, Awad HA, O'Keefe RJ. "Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2009 Jun 0; 27(6):833-40.