Publications
Showing all 45 journal articles & 0 books available
Journal Articles
2023
Osborn RM, Leach J, Zanche M, Ashton JM, Chu C, Thakar J, Dewhurst S, Rosenberger S, Pavelka M, Pryhuber GS, Mariani TJ, Anderson CS. "Preparation of noninfectious scRNAseq samples from SARS-CoV-2-infected epithelial cells." PloS one.. 2023 18(2):e0281898. Epub 2023 Feb 24.
4/11/2022
Khazan N, Kim KK, Hansen JN, Singh NA, Moore T, Snyder CWA, Pandita R, Strawderman M, Fujihara M, Takamura Y, Jian Y, Battaglia N, Yano N, Teramoto Y, Arnold LA, Hopson R, Kishor K, Nayak S, Ojha D, Sharon A, Ashton JM, Wang J, Milano MT, Miyamoto H, Linehan DC, Gerber SA, Kawar N, Singh AP, Tabdanov ED, Dokholyan NV, Kakuta H, Jurutka PW, Schor NF, Rowswell-Turner RB, Singh RK, Moore RG. "Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors ." Journal of medicinal chemistry.. 2022 Apr 11; Epub 2022 Apr 11.
3/24/2022
Morrell CN, Mix D, Aggarwal A, Bhandari R, Godwin M, Owens Iii AP, Lyden SP, Doyle A, Krauel K, Rondina MT, Mohan A, Lowenstein CJ, Shim S, Stauffer S, Josyula VP, Ture SK, Yule DI, Wagner Iii LE, Ashton JM, Elbadawi A, Cameron SJ. "Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms." The Journal of clinical investigation.. 2022 Mar 24; Epub 2022 Mar 24.
2/22/2022
Kallenbach JG, Freeberg MAT, Abplanalp D, Alenchery RG, Ajalik RE, Muscat S, Myers JA, Ashton JM, Loiselle A, Buckley MR, van Wijnen AJ, Awad HA. "Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse." Scientific reports.. 2022 Feb 22; 12(1):3026. Epub 2022 Feb 22.
2022
Piekna-Przybylska D, Na D, Zhang J, Baker C, Ashton JM, White PM. "Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor indicates a cell-specific response that promotes CD44 activation." Frontiers in cellular neuroscience.. 2022 16:1096872. Epub 2023 Jan 06.
12/21/2021
Misra A, Baker CD, Pritchett EM, Burgos Villar KN, Ashton JM, Small EM. "Characterizing Neonatal Heart Maturation, Regeneration, and Scar Resolution Using Spatial Transcriptomics." Journal of cardiovascular development and disease.. 2021 Dec 21; 9(1)Epub 2021 Dec 21.
12/15/2021
Ashton JM, Rehrauer H, Myers J, Myers J, Zanche M, Balys M, Foox J, Mason CE, Steen R, Kuentzel M, Aquino C, Garcia-Reyero N, Chittur SV. "Comparative Analysis of Single-Cell RNA Sequencing Platforms and Methods." Journal of biomolecular techniques : JBT.. 2021 Dec 15; 32(4)
7/6/2021
Quijada P, Trembley MA, Misra A, Myers JA, Baker CD, Pérez-Hernández M, Myers JR, Dirkx RA, Cohen ED, Delmar M, Ashton JM, Small EM. "Coordination of endothelial cell positioning and fate specification by the epicardium." Nature communications.. 2021 Jul 6; 12(1):4155. Epub 2021 Jul 06.
5/2021
Ho TC, Kim HS, Chen Y, Li Y, LaMere MW, Chen C, Wang H, Gong J, Palumbo CD, Ashton JM, Kim HW, Xu Q, Becker MW, Leong KW. "Scaffold-mediated CRISPR-Cas9 delivery system for acute myeloid leukemia therapy." Science advances.. 2021 May; 7(21)Epub 2021 May 19.
4/7/2021
Burke RM, Dirkx RA, Quijada P, Lighthouse JK, Mohan A, O'Brien M, Wojciechowski W, Woeller C, Phipps RP, Alexis JD, Ashton J, Small EM. "Prevention of Fibrosis and Pathological Cardiac Remodeling by Salinomycin." Circulation research.. 2021 Apr 7; Epub 2021 Apr 07.
6/29/2020
Schroeder GM, Dutta D, Cavender CE, Jenkins JL, Pritchett EM, Baker CD, Ashton JM, Mathews DH, Wedekind JE. "Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation." Nucleic acids research.. 2020 Jun 29; Epub 2020 Jun 29.
4/2020
Mische SM, Fisher NC, Meyn SM, Church KS, Hegstad-Davies RL, Weis-Garcia F, Adams M, Ashton JM, Delventhal KM, Dragon JA, Holmes L, Jagtap P, Kubow KE, Mason CE, Palmblad M, Searle BC, Turck CW, Knudtson KL. "A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups." Journal of biomolecular techniques : JBT.. 2020 Apr; 31(1):11-26.
4/2020
Pei S, Pollyea DA, Gustafson A, Stevens BM, Minhajuddin M, Fu R, Riemondy KA, Gillen AE, Sheridan RM, Kim J, Costello JC, Amaya ML, Inguva A, Winters A, Ye H, Krug A, Jones CL, Adane B, Khan N, Ponder J, Schowinsky J, Abbott D, Hammes A, Myers JR, Ashton JM, Nemkov T, D'Alessandro A, Gutman JA, Ramsey HE, Savona MR, Smith CA, Jordan CT. "Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia." Cancer discovery.. 2020 Apr; 10(4):536-551. Epub 2020 Jan 23.
1/10/2020
Herbert ZT, Thimmapuram J, Xie S, Kershner JP, Kolling FW, Ringelberg CS, LeClerc A, Alekseyev YO, Fan J, Podnar JW, Stevenson HS, Sommerville G, Gupta S, Berkeley M, Koeman J, Perera A, Scott AR, Grenier JK, Malik J, Ashton JM, Pivarski KL, Wang X, Kuffel G, Mesa TE, Smith AT, Shen J, Takata Y, Volkert TL, Love JA, Zhang Y, Wang J, Xuei X, Adams M, Levine SS. "Multisite Evaluation of Next-Generation Methods for Small RNA Quantification." Journal of biomolecular techniques : JBT.. 2020 Jan 10; Epub 2020 Jan 10.
4/9/2019
Li D, Chiu G, Lipe B, Hopkins RA, Lillis J, Ashton JM, Paul S, Aljitawi OS. "Decellularized Wharton jelly matrix: a biomimetic scaffold for ex vivo hematopoietic stem cell culture." Blood advances.. 2019 Apr 9; 3(7):1011-1026.
4/2/2019
Adane B, Ye H, Khan N, Pei S, Minhajuddin M, Stevens BM, Jones CL, D'Alessandro A, Reisz JA, Zaberezhnyy V, Gasparetto M, Ho TC, Kelly KK, Myers JR, Ashton JM, Siegenthaler J, Kume T, Campbell EL, Pollyea DA, Becker MW, Jordan CT. "The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells." Cell reports.. 2019 Apr 2; 27(1):238-254.e6.
10/8/2018
Ye H, Adane B, Khan N, Alexeev E, Nusbacher N, Minhajuddin M, Stevens BM, Winters AC, Lin X, Ashton JM, Purev E, Xing L, Pollyea DA, Lozupone CA, Serkova NJ, Colgan SP, Jordan CT. "Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells." Cancer cell.. 2018 Oct 8; 34(4):659-673.e6. Epub 2018 Sep 27.
9/18/2018
Wang W, Friedland SC, Guo B, O'Dell MR, Alexander WB, Whitney-Miller CL, Agostini-Vulaj D, Huber AR, Myers JR, Ashton JM, Dunne RF, Steiner LA, Hezel AF. "ARID1A, a SWI/SNF subunit, is critical to acinar cell homeostasis and regeneration and is a barrier to transformation and epithelial-mesenchymal transition in the pancreas." Gut.. 2018 Sep 18; Epub 2018 Sep 18.
7/5/2018
Pei S, Minhajuddin M, Adane B, Khan N, Stevens BM, Mack SC, Lai S, Rich JN, Inguva A, Shannon KM, Kim H, Tan AC, Myers JR, Ashton JM, Neff T, Pollyea DA, Smith CA, Jordan CT. "AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells." Cell stem cell.. 2018 Jul 5; 23(1):86-100.e6. Epub 2018 Jun 14.
4/19/2018
Schott EM, Farnsworth CW, Grier A, Lillis JA, Soniwala S, Dadourian GH, Bell RD, Doolittle ML, Villani DA, Awad H, Ketz JP, Kamal F, Ackert-Bicknell C, Ashton JM, Gill SR, Mooney RA, Zuscik MJ. "Targeting the gut microbiome to treat the osteoarthritis of obesity." JCI insight.. 2018 Apr 19; 3(8)Epub 2018 Apr 19.
2/22/2018
Scheible KM, Emo J, Laniewski N, Baran AM, Peterson DR, Holden-Wiltse J, Bandyopadhyay S, Straw AG, Huyck H, Ashton JM, Tripi KS, Arul K, Werner E, Scalise T, Maffett D, Caserta M, Ryan RM, Reynolds AM, Ren CL, Topham DJ, Mariani TJ, Pryhuber GS. "T cell developmental arrest in former premature infants increases risk of respiratory morbidity later in infancy." JCI insight.. 2018 Feb 22; 3(4)Epub 2018 Feb 22.
1/2018
Wong EL, Lutz NM, Hogan VA, Lamantia CE, McMurray HR, Myers JR, Ashton JM, Majewska AK. "Developmental alcohol exposure impairs synaptic plasticity without overtly altering microglial function in mouse visual cortex." Brain, behavior, and immunity.. 2018 Jan; 67:257-278. Epub 2017 Sep 14.
7/26/2017
Bhattacharya S, Rosenberg AF, Peterson DR, Grzesik K, Baran AM, Ashton JM, Gill SR, Corbett AM, Holden-Wiltse J, Topham DJ, Walsh EE, Mariani TJ, Falsey AR. "Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness." Scientific reports.. 2017 Jul 26; 7(1):6548. Epub 2017 Jul 26.
6/16/2017
Hilimire TA, Chamberlain JM, Anokhina V, Bennett RP, Swart O, Myers JR, Ashton JM, Stewart RA, Featherston AL, Gates K, Helms ED, Smith HC, Dewhurst S, Miller BL. "HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi-Drug-Resistant HIV in Human Cells." ACS chemical biology.. 2017 Jun 16; 12(6):1674-1682. Epub 2017 May 05.
6/15/2017
Shen J, Wang C, Li D, Xu T, Myers J, Ashton JM, Wang T, Zuscik MJ, McAlinden A, O'Keefe RJ. "DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism." JCI insight.. 2017 Jun 15; 2(12)Epub 2017 Jun 15.
6/2017
Gasparetto M, Pei S, Minhajuddin M, Khan N, Pollyea DA, Myers JR, Ashton JM, Becker MW, Vasiliou V, Humphries KR, Jordan CT, Smith CA. "Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1." Haematologica.. 2017 Jun; 102(6):1054-1065. Epub 2017 Mar 09.
5/26/2017
Elbarbary RA, Miyoshi K, Myers JR, Du P, Ashton JM, Tian B, Maquat LE. "Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G/S phase transition." Science.. 2017 May 26; 356(6340):859-862.
3/14/2017
Ram J, Flamm G, Balys M, Sivagnanalingam U, Rothberg PG, Iqbal A, Myers JR, Corbett A, Ashton JM, Mendler JH. "Index case of acute myeloid leukemia in a family harboring a novel germ line mutation." Blood advances.. 2017 Mar 14; 1(8):500-503. Epub 2017 Mar 14.
11/25/2016
Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT. "Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells." The Journal of biological chemistry.. 2016 Nov 25; 291(48):25280.
10/14/2016
Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT. "Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells." The Journal of biological chemistry.. 2016 Oct 14; 291(42):21984-22000. Epub 2016 Aug 29.
9/29/2016
Ho TC, LaMere M, Stevens BM, Ashton JM, Myers JR, O'Dwyer KM, Liesveld JL, Mendler JH, Guzman M, Morrissette JD, Zhao J, Wang ES, Wetzler M, Jordan CT, Becker MW. "Evolution of acute myelogenous leukemia stem cell properties after treatment and progression." Blood.. 2016 Sep 29; 128(13):1671-8. Epub 2016 Jul 15.
7/7/2016
Ye H, Adane B, Khan N, Sullivan T, Minhajuddin M, Gasparetto M, Stevens B, Pei S, Balys M, Ashton JM, Klemm DJ, Woolthuis CM, Stranahan AW, Park CY, Jordan CT. "Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche." Cell stem cell.. 2016 Jul 7; 19(1):23-37. Epub 2016 Jun 30.
2015
Sivagnanalingam U, Balys M, Eberhardt A, Wang N, Myers JR, Ashton JM, Becker MW, Calvi LM, Mendler JH. "Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia." PloS one.. 2015 10(7):e0132375. Epub 2015 Jul 15.
2015
Baras AS, Mitchell CJ, Myers JR, Gupta S, Weng LC, Ashton JM, Cornish TC, Pandey A, Halushka MK. "miRge - A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy." PloS one.. 2015 10(11):e0143066. Epub 2015 Nov 16.
11/22/2013
Pei S, Minhajuddin M, Callahan KP, Balys M, Ashton JM, Neering SJ, Lagadinou ED, Corbett C, Ye H, Liesveld JL, O'Dwyer KM, Li Z, Shi L, Greninger P, Settleman J, Benes C, Hagen FK, Munger J, Crooks PA, Becker MW, Jordan CT. "Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells." The Journal of biological chemistry.. 2013 Nov 22; 288(47):33542-58. Epub 2013 Oct 02.
7/8/2013
Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL. "In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling." Cancer cell.. 2013 Jul 8; 24(1):45-58. Epub 2013 Jun 13.
3/7/2013
Lagadinou ED, Sach A, Callahan K, Rossi RM, Neering SJ, Minhajuddin M, Ashton JM, Pei S, Grose V, O'Dwyer KM, Liesveld JL, Brookes PS, Becker MW, Jordan CT. "BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells." Cell stem cell.. 2013 Mar 7; 12(3):329-41. Epub 2013 Jan 17.
3/2013
Ganeshan V, Ashton J, Schor NF. "p75NTR: an enhancer of fenretinide toxicity in neuroblastoma." Cancer chemotherapy and pharmacology.. 2013 Mar; 71(3):777-87. Epub 2013 Jan 13.
9/7/2012
Ashton JM, Balys M, Neering SJ, Hassane DC, Cowley G, Root DE, Miller PG, Ebert BL, McMurray HR, Land H, Jordan CT. "Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells." Cell stem cell.. 2012 Sep 7; 11(3):359-72. Epub 2012 Aug 02.
4/2012
Zhao C, Xiu Y, Ashton J, Xing L, Morita Y, Jordan CT, Boyce BF. "Noncanonical NF-?B signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions." Stem cells.. 2012 Apr; 30(4):709-18.
1/12/2012
Frisch BJ, Ashton JM, Xing L, Becker MW, Jordan CT, Calvi LM. "Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia." Blood.. 2012 Jan 12; 119(2):540-50. Epub 2011 Sep 28.
11/2010
Galloway CA, Ashton J, Sparks JD, Mooney RA, Smith HC. "Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes." Biochimica et biophysica acta.. 2010 Nov; 1802(11):976-85. Epub 2010 Jun 09.
10/1/2007
Neering SJ, Bushnell T, Sozer S, Ashton J, Rossi RM, Wang PY, Bell DR, Heinrich D, Bottaro A, Jordan CT. "Leukemia stem cells in a genetically defined murine model of blast-crisis CML." Blood.. 2007 Oct 1; 110(7):2578-85. Epub 2007 Jun 29.
9/2006
Delvecchio VG, Connolly JP, Alefantis TG, Walz A, Quan MA, Patra G, Ashton JM, Whittington JT, Chafin RD, Liang X, Grewal P, Khan AS, Mujer CV. "Proteomic profiling and identification of immunodominant spore antigens of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis." Applied and environmental microbiology.. 2006 Sep; 72(9):6355-63.
12/2004
Alefantis T, Grewal P, Ashton J, Khan AS, Valdes JJ, Del Vecchio VG. "A rapid and sensitive magnetic bead-based immunoassay for the detection of staphylococcal enterotoxin B for high-through put screening." Molecular and cellular probes.. 2004 Dec; 18(6):379-82.