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Shawn P. Murphy, Ph.D.


Showing all 36 journal articles & 0 books available

Journal Articles

Agbayani G, Clark K, Sandhu JK, Hewitt M, Sad S, Murphy SP, Krishnan L. "IFN-alpha receptor deficiency enhances host resistance to oral Salmonella enterica serovar Typhimurium infection during murine pregnancy." American journal of reproductive immunology : AJRI.. 2021 May 15; :e13454. Epub 2021 May 15.

Perry ID, Nguyen T, Sherina V, Love TMT, Miller RK, Krishnan L, Murphy SP. "Analysis of the capacity of Salmonella enterica Typhimurium to infect the human Placenta." Placenta.. 2019 Aug 0; 83:43-52. Epub 2019 Jun 26.

Perry ID, Krishnan L, Murphy SP. "SLC11A1 is expressed in the human placenta across multiple gestational ages." Placenta.. 2019 Jan 0; 75:23-26. Epub 2018 Nov 22.

Spinelli P, Latchney SE, Reed JM, Fields A, Baier BS, Lu X, McCall MN, Murphy SP, Mak W, Susiarjo M. "Identification of the novel Ido1 imprinted locus and its potential epigenetic role in pregnancy loss." Human molecular genetics.. 2018 Nov 7; Epub 2018 Nov 07.

Gerber SA, Lim JY, Connolly KA, Sedlacek AL, Barlow ML, Murphy SP, Egilmez NK, Lord EM. "Radio-responsive tumors exhibit greater intratumoral immune activity than nonresponsive tumors." International journal of cancer.. 2014 May 15; 134(10):2383-92. Epub 2013 Nov 11.

Bushway ME, Gerber SA, Fenton BM, Miller RK, Lord EM, Murphy SP. "Morphological and phenotypic analyses of the human placenta using whole mount immunofluorescence." Biology of reproduction.. 2014 May 0; 90(5):110. Epub 2014 Mar 19.

Lim JY, Gerber SA, Murphy SP, Lord EM. "Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells." Cancer immunology, immunotherapy : CII.. 2014 Mar 0; 63(3):259-71. Epub 2013 Dec 20.

Cycon KA, Mulvaney K, Rimsza LM, Persky D, Murphy SP. "Histone deacetylase inhibitors activate CIITA and MHC class II antigen expression in diffuse large B-cell lymphoma." Immunology.. 2013 Oct 0; 140(2):259-72.

Gerber SA, Sedlacek AL, Cron KR, Murphy SP, Frelinger JG, Lord EM. "IFN-? mediates the antitumor effects of radiation therapy in a murine colon tumor." The American journal of pathology.. 2013 Jun 0; 182(6):2345-54. Epub 2013 Apr 12.

Katzman PJ, Shawn M, Oble D. "Immunohistochemical analysis reveals an influx of regulatory T cells and focal trophoblastic STAT-1 phosphorylation in chronic villitis of unknown etiology." Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.. 2011 14(4):284-93. Epub 2011 Feb 23.

Bushway M, Cycon KA, Mulvaney K, Murphy SP. "Coordinate loss of MHC class II expression in the diffuse large B cell lymphoma cell line OCI-Ly2 is due to a novel mutation in RFX-AP." Immunogenetics.. 2010 Feb 0; 62(2):109-16. Epub 2009 Dec 19.

Choi, J.C.; Holtz, R.; Murphy, S.P. "Histone deacetylases inhibit IFN-y-inducible gene expression in mouse trophoblast cells". J Immunol. 2009; 182(10): 6307-6315.

Apps, R.A.; Murphy, S.P.; Fernando, R.; Gardner, L.; Ahad, T.; Moffett, A. "Human Leukocyte Antigen (HLA) expression by normal trophoblast cells and placental cell lines using a novel method to characterize allotype specificities of anti-HLA antibodies" . Immunology. 2009; 127(1): 26-39.

Rimsza, L.M.; Chan, W.C.; Gascoyne, R.D.; Campo, E.; Jaffe, E.S.; Staudt, L.M.; Delabie, J.; Rosenwald, A.; Murphy S.P. "CIITA or RFX Coding Region Loss of Function Mutations Occur Rarely in Diffuse Large B Cell Lymphoma Cases and Cell Lines with Low Levels of Major Histocompatibility Complex Class II Expression." Haematologica. 2009; 94(4): 596-598.

Murphy, S.P.; Tayade, C.; Ashkar, A.A.; Hattta, K.; Zhang, J.; Croy B.A. "Interferon-gamma in successful pregnancies" . Biol Reprod. 2009; 80(5): 848-859.

Cycon, K.; Clements, J; Holtz, R.; Fuji, H.; Murphy, S.P. "The immunogenicity of L1210 lymphoma clones correlates with the ability to function as antigen presenting cells" . Immunology. 2009; 128: e641-651.

Cycon, K.; Rimsza, L.; Murphy, S.P. "Alterations in CIITA constitute a common mechanism accounting for downregulation of MHC class II expression in diffuse large B cell lymphoma (DLBCL)" . Experimental Hematology. 2009; 37(2): 184-194.

Choi JC, Holtz R, Petroff MG, Alfaidy N, Murphy SP. "Dampening of IFN-gamma-inducible gene expression in human choriocarcinoma cells is due to phosphatase-mediated inhibition of the JAK/STAT-1 pathway." The Journal of immunology : official journal of the American Association of Immunologists.. 2007 Feb 1; 178(3):1598-607.

Choi, J.C.; Petroff, M.G.; Holtz, R.; Alfaidy, N.; Challis, J.R.; Murphy, S.P. "Dampening of IFN-y-inducible gene expression in human choriocarcinoma cells is due to phosphatase-mediated inhibition of the JAK/STAT-1 pathway" . J Immunol. 2007; 178(3): 1589-1607.

Murphy SP, Choi JC, Holtz R. "Regulation of major histocompatibility complex class II gene expression in trophoblast cells." Reproductive biology and endocrinology : RB&E.. 2004 Jul 5; 2:52. Epub 2004 Jul 05.

Chang CC, Murphy SP, Ferrone S. "Differential in vivo and in vitro HLA-G expression in melanoma cells: potential mechanisms." Human immunology.. 2003 Nov 0; 64(11):1057-63.

Holtz R, Choi JC, Petroff MG, Piskurich JF, Murphy SP. "Class II transactivator (CIITA) promoter methylation does not correlate with silencing of CIITA transcription in trophoblasts." Biology of reproduction.. 2003 Sep 0; 69(3):915-24. Epub 2003 May 14.

Murphy SP, Holtz R, Lewandowski N, Tomasi TB, Fuji H. "DNA alkylating agents alleviate silencing of class II transactivator gene expression in L1210 lymphoma cells." The Journal of immunology : official journal of the American Association of Immunologists.. 2002 Sep 15; 169(6):3085-93.

Li LH, Sen A, Murphy SP, Jahreis GP, Fuji H, Hui SW. "Apoptosis induced by DNA uptake limits transfection efficiency." Experimental cell research.. 1999 Dec 15; 253(2):541-50.

Murphy SP, Tomasi TB. "Absence of MHC class II antigen expression in trophoblast cells results from a lack of class II transactivator (CIITA) gene expression." Molecular reproduction and development.. 1998 Sep 0; 51(1):1-12.

Murphy SP, Gollnick SO, Pazmany T, Maier P, Elkin G, Tomasi TB. "Repression of MHC class II gene transcription in trophoblast cells by novel single-stranded DNA binding proteins." Molecular reproduction and development.. 1997 Aug 0; 47(4):390-403.

Pazmany T, Murphy SP, Gollnick SO, Brooks SP, Tomasi TB. "Activation of multiple transcription factors and fos and jun gene family expression in cells exposed to a single electric pulse." Experimental cell research.. 1995 Nov 0; 221(1):103-10.

Bhattacharyya T, Karnezis AN, Murphy SP, Hoang T, Freeman BC, Phillips B, Morimoto RI. "Cloning and subcellular localization of human mitochondrial hsp70." The Journal of biological chemistry.. 1995 Jan 27; 270(4):1705-10.

Mathur SK, Sistonen L, Brown IR, Murphy SP, Sarge KD, Morimoto RI. "Deficient induction of human hsp70 heat shock gene transcription in Y79 retinoblastoma cells despite activation of heat shock factor 1." Proceedings of the National Academy of Sciences of the United States of America.. 1994 Aug 30; 91(18):8695-9.

Murphy SP, Gorzowski JJ, Sarge KD, Phillips B. "Characterization of constitutive HSF2 DNA-binding activity in mouse embryonal carcinoma cells." Molecular and cellular biology.. 1994 Aug 0; 14(8):5309-17.

Carr, V.M.; Murphy, S.P.; Morimoto, R.I.; Farbman, A. "Small subclass of olfactory neurons with specific bulbar projections reactive with monoclonal antibodies to the hsp70 heat shock protein." Carr, V.M., Murphy, S.P., Morimoto, R.I. and Farbman, A. 1994; 348: 150-160.

Sarge, K.D.; Murphy, S.P.; Morimoto, R.I. "Activation of heat shock gene transcription of HSF1 involves oligomerization, nuclear translocation and acquisition of DNA binding and can occur in the absence of stress." Mol. Cell. Biol. 1993; 13(1392-1407).

Kroeger, P.E.; Sarge, K.D.; Murphy, S.P.; Naki, A.; Morimoto, R.I. "Differential regulation of Heat shock gene transcription by a family of heat shock factors. (Review)." J. Occup. Environ. Health (Japan). 1993; 15: 55-63.

Abravaya K, Myers MP, Murphy SP, Morimoto RI. "The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression." Genes & development.. 1992 Jul 0; 6(7):1153-64.

Espeseth, A.; Murphy, S.P.; Linney, E. "Retinoic acid receptor expression vector inhibits differentiation of F9 embryonal carcinoma cells". Espeseth, A., Murphy, S.P. and Linney, E. 1989; 3: 1647-1656.

Murphy SP, Garbern J, Odenwald WF, Lazzarini RA, Linney E. "Differential expression of the homeobox gene Hox-1.3 in F9 embryonal carcinoma cells." Proceedings of the National Academy of Sciences of the United States of America.. 1988 Aug 0; 85(15):5587-91.