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Edward Brown, Ph.D.

Contact Information

Research Labs

Faculty Appointments

Credentials

Education

1992
BS | Wake Forest University
Physics

1995
MS | Cornell University
Physics

1999
PhD | Cornell University
Physics

Post-doctoral Training & Residency

07/1999 - 12/2001
Post-Doctoral Fellow, Department of Radiation Oncology, Harvard Medical School / Massachusetts General Hospital. Laboratory of Dr. Rakesh K. Jain.

Awards

2009 - 2014
NIH Director's New Innovator Award
Sponsor: NIH

2007 - 2011
Pew Scholar in the Biomedical Sciences Award
Sponsor: Pew Charitable Trusts

2005 - 2010
Era of Hope Scholar Award
Sponsor: Department of Defense Breast Cancer Research Program

2000
AACR-Aflac Scholars in Cancer Research Award
Sponsor: AFLAC

1992
Phi Beta Kappa
Sponsor: Wake Forest University
Location: Winston-Salem, NC

1992
Speas Award for Excellence in Physics
Sponsor: Wake Forest University
Location: Winston-Salem, NC

1984 - 1988
Reynolds Scholarship (full room, full board, full tuition, stipend)
Sponsor: Wake Forest University
Location: Winston-Salem, NC

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Patents

Patent Title: System and Method for Measuring the Ratio of Forward-Propagating to Back-Propagating Second Harmonic-Generation Signal, and Applications Thereof
Patent #: 8,812,085
Issue Date: Aug 19, 2014
Country: United States
Invented By: Edward Brown III, Xiaoxing Han

Patent Title: Methods of Treating Cancer Using The Calcitonin-Gene Related Peptide ("CGRP") Receptor Antagonist CGRP8-37
Patent #: 8,394,767
Issue Date: Mar 12, 2013
Country: United States
Invented By: Edward Brown III, Ian Dickerson

Patent Title: Method and Apparatus to Diagnose the Metatstatic or Progressive Potential of Cancer, Fibrosis and other Diseases
Patent #: 10,765,376
Issue Date: Sep 08, 2020
Country: United States
Invented By: Edward Brown III, Kathleen Burke, Robert Matthew Kottmann, Seth W Perry, Jesse W Sharpe, Patricia Janet Sime

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Publications

Journal Articles

2/9/2022
Desa DE, Wu W, Brown RM, Brown EB, Hill RL, Turner BM, Brown EB. "Second-Harmonic Generation Imaging Reveals Changes in Breast Tumor Collagen Induced by Neoadjuvant Chemotherapy." Cancers.. 2022 Feb 9; 14(4)Epub 2022 Feb 09.

11/12/2021
Schilling K, Brown E, Zhang X. "NAD(P)H autofluorescence lifetime imaging enables single cell analyses of cellular metabolism of osteoblasts in vitro and in vivo via two-photon microscopy." Bone.. 2021 Nov 12; :116257. Epub 2021 Nov 12.

7/26/2021
Zhai Y, Schilling K, Wang T, El Khatib M, Vinogradov S, Brown EB, Zhang X. "Spatiotemporal blood vessel specification at the osteogenesis and angiogenesis interface of biomimetic nanofiber-enabled bone tissue engineering." Biomaterials.. 2021 Jul 26; 276:121041. Epub 2021 Jul 26.

Books & Chapters

2011
Chapter Title: Single and Multiphoton Fluorescence Recovery After Photobleaching
Book Title: Imaging: A Laboratory Manual
Author List: Sullivan K, Majewska A, Brown E
Edited By: Yuste R
Published By: Cold Spring Harbor Laboratory Press 2011 in Cold Spring Harbor

2011
Chapter Title: Imaging Tumors in the Brain
Book Title: Imaging in Neuroscience: A Laboratory Manual
Author List: Madden K, Zettel M, Majewska A, Brown E
Edited By: Helmchen F, Konnerth A
Published By: Cold Spring Harbor Laboratory Press, In Press 2011 in Cold Spring Harbor

2011
Chapter Title: Second Harmonic Imaging of Tumors
Book Title: Second Harmonic Generation Imaging
Author List: Han X, Perry S, Brown E
Edited By: Campagnola P, Pavone F
Published By: Taylor and Francis Press, In Preparation 2011

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