Publications
Showing all 116 journal articles & 9 books available
Journal Articles
4/26/2023
Liu J, Schiralli-Lester GM, Norman R, Dean DA. "Upregulation of alveolar fluid clearance is not sufficient for Na,K-ATPase ? subunit-mediated gene therapy of LPS-induced acute lung injury in mice." Scientific reports.. 2023 Apr 26; 13(1):6792. Epub 2023 Apr 26.
2/11/2023
Gurunian A, Dean DA. "Multiple conductance states of lipid pores during Voltage-Clamp electroporation." Bioelectrochemistry.. 2023 Feb 11; 151:108396. Epub 2023 Feb 11.
5/19/2022
Gurunian A, Dean DA. "Modeling and simulation of current-clamp electroporation." Bioelectrochemistry.. 2022 May 19; 147:108162. Epub 2022 May 19.
10/21/2021
Liu J, Dean DA. "Gene transfer of MRCK? rescues lipopolysaccharide-induced acute lung injury by restoring alveolar capillary barrier function." Scientific reports.. 2021 Oct 21; 11(1):20862. Epub 2021 Oct 21.
1/28/2021
Bai H, Zhou R, Barravecchia M, Norman R, Friedman AE, Yu D, Lin X, Young JL, Dean DA. "MRCK? interacts with and mediates Na+, K+-ATPase-induced tight junction assembly in the lung epithelium." JCI insight.. 2021 Jan 28; Epub 2021 Jan 28.
1/14/2021
Eliseeva SI, Knowlden ZA, Lester GM, Dean DA, Georas SN, Chapman TJ. "Changes in lung immune cell infiltrates after electric field treatment in mice." Scientific reports.. 2021 Jan 14; 11(1):1453. Epub 2021 Jan 14.
2021
Welch JJ, Dean DA, Nilsson BL. "Synthesis and Application of Peptide-siRNA Nanoparticles from Disulfide-Constrained Cyclic Amphipathic Peptides for the Functional Delivery of Therapeutic Oligonucleotides to the Lung." Methods in molecular biology.. 2021 2208:49-67.
2021
Liu J, Dean DA. "Gene Therapy for Acute Respiratory Distress Syndrome." Frontiers in physiology.. 2021 12:786255. Epub 2022 Jan 17.
11/12/2020
Baliga UK, Dean DA. "Pulmonary gene delivery-Realities and possibilities." Experimental biology and medicine. 2020 Nov 12; :1535370220965985. Epub 2020 Nov 12.
1/16/2020
Ávila-Pérez G, Nogales A, Park JG, Vasquez DM, Dean DA, Barravecchia M, Perez DR, Almazán F, Martínez-Sobrido L. "In vivo rescue of recombinant Zika virus from an infectious cDNA clone and its implications in vaccine development." Scientific reports.. 2020 Jan 16; 10(1):512. Epub 2020 Jan 16.
10/29/2019
Steiner LA, Getman M, Schiralli Lester GM, Iqbal MA, Katzman P, Szafranski P, Stankiewicz P, Bhattacharya S, Mariani T, Pryhuber G, Lin X, Young JL, Dean DA, Scheible K. "Disruption of normal patterns of FOXF1 expression in a lethal disorder of lung development." Journal of medical genetics.. 2019 Oct 29; Epub 2019 Oct 29.
7/27/2019
Jagrosse ML, Dean DA, Rahman A, Nilsson BL. "RNAi therapeutic strategies for acute respiratory distress syndrome." Translational research : the journal of laboratory and clinical medicine.. 2019 Jul 27; Epub 2019 Jul 27.
5/1/2019
Leonard A, Millar MW, Slavin SA, Bijli KM, Dionisio Santos, Dean DA, Fazal F, Rahman A. "Critical role of autophagy regulator Beclin1 in endothelial cell inflammation and barrier disruption." Cellular signalling.. 2019 May 1; Epub 2019 May 01.
12/22/2017
Bai H, Schiralli Lester GM, Petishnok LC, Dean DA. "Cytoplasmic transport and nuclear import of plasmid DNA." Bioscience reports.. 2017 Dec 22; 37(6)Epub 2017 Nov 29.
7/2017
Barnett RC, Lin X, Barravecchia M, Norman RA, de Mesy Bentley KL, Fazal F, Young JL, Dean DA. "Featured Article: Electroporation-mediated gene delivery of surfactant protein B (SP-B) restores expression and improves survival in mouse model of SP-B deficiency." Experimental biology and medicine. 2017 Jul; 242(13):1345-1354. Epub 2017 Jun 05.
6/24/2017
Rahmani K, Dean DA. "Leptomycin B alters the subcellular distribution of CRM1 (Exportin 1)." Biochemical and biophysical research communications.. 2017 Jun 24; 488(2):253-258. Epub 2017 Apr 12.
12/2016
Parikh P, Bai H, Swartz MF, Alfieris GM, Dean DA. "Identification of differentially regulated genes in human patent ductus arteriosus." Experimental biology and medicine. 2016 Dec; 241(18):2112-2118. Epub 2016 Jul 28.
10/2016
Gottfried L, Lin X, Barravecchia M, Dean DA. "Identification of an alveolar type I epithelial cell-specific DNA nuclear import sequence for gene delivery." Gene therapy.. 2016 Oct; 23(10):734-742. Epub 2016 Jul 01.
6/9/2016
Welch JJ, Swanekamp RJ, King C, Dean DA, Nilsson BL. "Functional Delivery of siRNA by Disulfide-Constrained Cyclic Amphipathic Peptides." ACS medicinal chemistry letters.. 2016 Jun 9; 7(6):584-9. Epub 2016 Mar 30.
6/2016
Lin X, Barravecchia M, Kothari P, Young JL, Dean DA. "?1-Na(+),K(+)-ATPase gene therapy upregulates tight junctions to rescue lipopolysaccharide-induced acute lung injury." Gene therapy.. 2016 Jun; 23(6):489-99. Epub 2016 Mar 17.
8/17/2015
Vernon MM, Dean DA, Dobson J. "DNA Targeting Sequence Improves Magnetic Nanoparticle-Based Plasmid DNA Transfection Efficiency in Model Neurons." International journal of molecular sciences.. 2015 Aug 17; 16(8):19369-86. Epub 2015 Aug 17.
7/9/2015
Huber AR, Tan D, Sun J, Dean D, Wu T, Zhou Z. "High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7." BMC gastroenterology.. 2015 Jul 9; 15:80. Epub 2015 Jul 09.
1/2015
Emr BM, Roy S, Kollisch-Singule M, Gatto LA, Barravecchia M, Lin X, Young JL, Wang G, Liu J, Satalin J, Snyder K, Nieman GF, Dean DA. "Electroporation-mediated gene delivery of Na+,K+ -ATPase, and ENaC subunits to the lung attenuates acute respiratory distress syndrome in a two-hit porcine model." Shock.. 2015 Jan; 43(1):16-23.
2015
Young JL, Dean DA. "Electroporation-mediated gene delivery." Advances in genetics.. 2015 89:49-88. Epub 2014 Dec 11.
2014
Young JL, Barravecchia MS, Dean DA. "Electroporation-mediated gene delivery to the lungs." Methods in molecular biology.. 2014 1121:189-204.
11/2013
Emr B, Gatto LA, Roy S, Satalin J, Ghosh A, Snyder K, Andrews P, Habashi N, Marx W, Ge L, Wang G, Dean DA, Vodovotz Y, Nieman G. "Airway pressure release ventilation prevents ventilator-induced lung injury in normal lungs." JAMA surgery.. 2013 Nov; 148(11):1005-12.
10/2013
Dean DA. "Cell-specific targeting strategies for electroporation-mediated gene delivery in cells and animals." The Journal of membrane biology.. 2013 Oct; 246(10):737-44. Epub 2013 Mar 24.
9/2013
Roy SK, Emr B, Sadowitz B, Gatto LA, Ghosh A, Satalin JM, Snyder KP, Ge L, Wang G, Marx W, Dean D, Andrews P, Singh A, Scalea T, Habashi N, Nieman GF. "Preemptive application of airway pressure release ventilation prevents development of acute respiratory distress syndrome in a rat traumatic hemorrhagic shock model." Shock.. 2013 Sep; 40(3):210-6.
6/2013
Badding MA, Dean DA. "Highly acetylated tubulin permits enhanced interactions with and trafficking of plasmids along microtubules." Gene therapy.. 2013 Jun; 20(6):616-24. Epub 2012 Sep 27.
4/2013
Badding MA, Lapek JD, Friedman AE, Dean DA. "Proteomic and functional analyses of protein-DNA complexes during gene transfer." Molecular therapy : the journal of the American Society of Gene Therapy.. 2013 Apr; 21(4):775-85. Epub 2012 Nov 20.
1/2013
Roy S, Habashi N, Sadowitz B, Andrews P, Ge L, Wang G, Roy P, Ghosh A, Kuhn M, Satalin J, Gatto LA, Lin X, Dean DA, Vodovotz Y, Nieman G. "Early airway pressure release ventilation prevents ARDS-a novel preventive approach to lung injury." Shock.. 2013 Jan; 39(1):28-38.
10/2012
Cramer F, Christensen CL, Poulsen TT, Badding MA, Dean DA, Poulsen HS. "Insertion of a nuclear factor kappa B DNA nuclear-targeting sequence potentiates suicide gene therapy efficacy in lung cancer cell lines." Cancer gene therapy.. 2012 Oct; 19(10):675-83. Epub 2012 Aug 17.
8/2012
O'Reilly MA, Yee M, Buczynski BW, Vitiello PF, Keng PC, Welle SL, Finkelstein N, Dean DA, Lawrence BP. "Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1." The American journal of pathology.. 2012 Aug; 181(2):441-51. Epub 2012 Jun 05.
8/2012
Roy S, Sadowitz B, Andrews P, Gatto LA, Marx W, Ge L, Wang G, Lin X, Dean DA, Kuhn M, Ghosh A, Satalin J, Snyder K, Vodovotz Y, Nieman G, Habashi N. "Early stabilizing alveolar ventilation prevents acute respiratory distress syndrome: a novel timing-based ventilatory intervention to avert lung injury." The journal of trauma and acute care surgery.. 2012 Aug; 73(2):391-400.
6/2012
Yao H, Chung S, Hwang JW, Rajendrasozhan S, Sundar IK, Dean DA, McBurney MW, Guarente L, Gu W, Rönty M, Kinnula VL, Rahman I. "SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice." The Journal of clinical investigation.. 2012 Jun; 122(6):2032-45. Epub 2012 May 01.
3/2012
Badding MA, Vaughan EE, Dean DA. "Transcription factor plasmid binding modulates microtubule interactions and intracellular trafficking during gene transfer." Gene therapy.. 2012 Mar; 19(3):338-46. Epub 2011 Jun 30.
3/2012
Badding MA, Vaughan EE, Dean DA. "Transcription factor plasmid binding modulates microtubule interactions and intracellular trafficking during gene transfer." Gene therapy.. 2012 Mar; 19(3):354. Epub 2011 Jul 21.
7/2011
Lin X, Dean DA. "Gene therapy for ALI/ARDS." Critical care clinics.. 2011 Jul; 27(3):705-18.
2/2011
Eldib M, Dean DA. "Cyclic stretch of alveolar epithelial cells alters cytoskeletal micromechanics." Biotechnology and bioengineering.. 2011 Feb; 108(2):446-53.
2011
Dean, D. A., M. Barravecchia, B. Danziger, and X. Lin. "Use of Electroporation for Efficacious Gene Delivery to the Lungs". ECS Trans. 2011; 35: 167-177.
9/2010
Staversky RJ, Vitiello PF, Yee M, Callahan LM, Dean DA, O'Reilly MA. "Epithelial ablation of Bcl-XL increases sensitivity to oxygen without disrupting lung development." American journal of respiratory cell and molecular biology.. 2010 Sep; 43(3):376-85. Epub 2009 Oct 30.
9/2010
Kaufman CD, Geiger RC, Dean DA. "Electroporation- and mechanical ventilation-mediated gene transfer to the lung." Gene therapy.. 2010 Sep; 17(9):1098-104. Epub 2010 Apr 29.
4/2010
Degiulio JV, Kaufman CD, Dean DA. "The SP-C promoter facilitates alveolar type II epithelial cell-specific plasmid nuclear import and gene expression." Gene therapy.. 2010 Apr; 17(4):541-9. Epub 2010 Jan 07.
4/2010
Lam AP, Dean DA. "Progress and prospects: nuclear import of nonviral vectors." Gene therapy.. 2010 Apr; 17(4):439-47. Epub 2010 Mar 04.
1/2010
Wang Y, Heilig KO, Minto AW, Chen S, Xiang M, Dean DA, Geiger RC, Chang A, Pravtcheva DD, Schlimme M, Deb DK, Wang Y, Heilig CW. "Nephron-deficient Fvb mice develop rapidly progressive renal failure and heavy albuminuria involving excess glomerular GLUT1 and VEGF." Laboratory investigation; a journal of technical methods and pathology.. 2010 Jan; 90(1):83-97. Epub 2009 Nov 16.
11/2009
Miller AM, Munkonge FM, Alton EW, Dean DA. "Identification of protein cofactors necessary for sequence-specific plasmid DNA nuclear import." Molecular therapy : the journal of the American Society of Gene Therapy.. 2009 Nov; 17(11):1897-903. Epub 2009 Jun 16.
10/2009
Yee M, Chess PR, McGrath-Morrow SA, Wang Z, Gelein R, Zhou R, Dean DA, Notter RH, O'Reilly MA. "Neonatal oxygen adversely affects lung function in adult mice without altering surfactant composition or activity." American journal of physiology. Lung cellular and molecular physiology.. 2009 Oct; 297(4):L641-9. Epub 2009 Jul 17.
9/25/2009
Munkonge FM, Amin V, Hyde SC, Green AM, Pringle IA, Gill DR, Smith JW, Hooley RP, Xenariou S, Ward MA, Leeds N, Leung KY, Chan M, Hillery E, Geddes DM, Griesenbach U, Postel EH, Dean DA, Dunn MJ, Alton EW. "Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import." The Journal of biological chemistry.. 2009 Sep 25; 284(39):26978-87. Epub 2009 Jul 28.
8/1/2009
Aistrup GL, Villuendas R, Ng J, Gilchrist A, Lynch TW, Gordon D, Cokic I, Mottl S, Zhou R, Dean DA, Wasserstrom JA, Goldberger JJ, Kadish AH, Arora R. "Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation." Cardiovascular research.. 2009 Aug 1; 83(3):481-92. Epub 2009 May 20.
7/2/2009
Miller AM, Dean DA. "Tissue-specific and transcription factor-mediated nuclear entry of DNA." Advanced drug delivery reviews.. 2009 Jul 2; 61(7-8):603-13. Epub 2009 Apr 23.
1/19/2009
Xavier J, Singh S, Dean DA, Rao NM, Gopal V. "Designed multi-domain protein as a carrier of nucleic acids into cells." Journal of controlled release : official journal of the Controlled Release Society.. 2009 Jan 19; 133(2):154-60. Epub 2008 Oct 11.
1/2009
Geiger RC, Kaufman CD, Lam AP, Budinger GR, Dean DA. "Tubulin acetylation and histone deacetylase 6 activity in the lung under cyclic load." American journal of respiratory cell and molecular biology.. 2009 Jan; 40(1):76-82. Epub 2008 Jul 17.
11/2008
Vaughan EE, Geiger RC, Miller AM, Loh-Marley PL, Suzuki T, Miyata N, Dean DA. "Microtubule acetylation through HDAC6 inhibition results in increased transfection efficiency." Molecular therapy : the journal of the American Society of Gene Therapy.. 2008 Nov; 16(11):1841-7. Epub 2008 Sep 09.
8/2008
Miller AM, Dean DA. "Cell-specific nuclear import of plasmid DNA in smooth muscle requires tissue-specific transcription factors and DNA sequences." Gene therapy.. 2008 Aug; 15(15):1107-15. Epub 2008 May 22.
7/2008
Young JL, Zimmer WE, Dean DA. "Smooth muscle-specific gene delivery in the vasculature based on restriction of DNA nuclear import." Experimental biology and medicine. 2008 Jul; 233(7):840-8. Epub 2008 Apr 29.
6/2008
Lam AP, Dean DA. "Cyclic stretch-induced nuclear localization of transcription factors results in increased nuclear targeting of plasmids in alveolar epithelial cells." The journal of gene medicine.. 2008 Jun; 10(6):668-78.
3/2008
Dean DA, Ramanathan T, Machado D, Sundararajan R. "Electrical Impedance Spectroscopy Study of Biological Tissues." Journal of electrostatics.. 2008 Mar; 66(3-4):165-177.
2008
Capaccio, C.; Stoykov, N.S.; Sundarajan, R.; and D.A. Dean. "Quantifying Induced Electric Field Strengths During Gene Transfer to the Intact Rat Vasculature." J Electrostatics. 2008; : (in press).
2008
Zhou R, Norton JE, Dean DA. "Electroporation-mediated gene delivery to the lungs." Methods in molecular biology.. 2008 423:233-47.
12/2007
Gasiorowski JZ, Dean DA. "Intranuclear trafficking of episomal DNA is transcription-dependent." Molecular therapy : the journal of the American Society of Gene Therapy.. 2007 Dec; 15(12):2132-9. Epub 2007 Jul 31.
10/2007
Mutlu GM, Green D, Bellmeyer A, Baker CM, Burgess Z, Rajamannan N, Christman JW, Foiles N, Kamp DW, Ghio AJ, Chandel NS, Dean DA, Sznajder JI, Budinger GR. "Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway." The Journal of clinical investigation.. 2007 Oct; 117(10):2952-61.
9/15/2007
Mutlu GM, Machado-Aranda D, Norton JE, Bellmeyer A, Urich D, Zhou R, Dean DA. "Electroporation-mediated gene transfer of the Na+,K+ -ATPase rescues endotoxin-induced lung injury." American journal of respiratory and critical care medicine.. 2007 Sep 15; 176(6):582-90. Epub 2007 Jun 07.
5/2007
Zhou R, Norton JE, Zhang N, Dean DA. "Electroporation-mediated transfer of plasmids to the lung results in reduced TLR9 signaling and inflammation." Gene therapy.. 2007 May; 14(9):775-80. Epub 2007 Mar 08.
3/15/2007
Bellmeyer A, Martino JM, Chandel NS, Scott Budinger GR, Dean DA, Mutlu GM. "Leptin resistance protects mice from hyperoxia-induced acute lung injury." American journal of respiratory and critical care medicine.. 2007 Mar 15; 175(6):587-94. Epub 2006 Dec 21.
3/2007
Zhou R, Dean DA. "Gene transfer of interleukin 10 to the murine cornea using electroporation." Experimental biology and medicine. 2007 Mar; 232(3):362-9.
2/2007
Kopp K, Gasiorowski JZ, Chen D, Gilmore R, Norton JT, Wang C, Leary DJ, Chan EK, Dean DA, Huang S. "Pol I transcription and pre-rRNA processing are coordinated in a transcription-dependent manner in mammalian cells." Molecular biology of the cell.. 2007 Feb; 18(2):394-403. Epub 2006 Nov 15.
2007
Capaccio, C., N. S. Stoykov, R. Sundararajan, and D. A. Dean. "Quantifying Induced Electric Field Strengths During Gene Transfer to the Intact Rat Vasculature." IEEE Trans. Biomed. Eng. 2007; .
12/2006
Vaughan EE, DeGiulio JV, Dean DA. "Intracellular trafficking of plasmids for gene therapy: mechanisms of cytoplasmic movement and nuclear import." Current gene therapy.. 2006 Dec; 6(6):671-681.
5/15/2006
Hillery E, Munkonge FM, Xenariou S, Dean DA, Alton EW. "Nondisruptive, sequence-specific coupling of fluorochromes to plasmid DNA." Analytical biochemistry.. 2006 May 15; 352(2):169-75. Epub 2006 Mar 09.
4/2006
Geiger RC, Taylor W, Glucksberg MR, Dean DA. "Cyclic stretch-induced reorganization of the cytoskeleton and its role in enhanced gene transfer." Gene therapy.. 2006 Apr; 13(8):725-31.
2/2006
Vaughan EE, Dean DA. "Intracellular trafficking of plasmids during transfection is mediated by microtubules." Molecular therapy : the journal of the American Society of Gene Therapy.. 2006 Feb; 13(2):422-8. Epub 2005 Nov 21.
9/2005
Gasiorowski JZ, Dean DA. "Postmitotic nuclear retention of episomal plasmids is altered by DNA labeling and detection methods." Molecular therapy : the journal of the American Society of Gene Therapy.. 2005 Sep; 12(3):460-7.
8/2005
Dean DA. "Nonviral gene transfer to skeletal, smooth, and cardiac muscle in living animals." American journal of physiology. Cell physiology.. 2005 Aug; 289(2):C233-45.
6/15/2005
Jones JC, Lane K, Hopkinson SB, Lecuona E, Geiger RC, Dean DA, Correa-Meyer E, Gonzales M, Campbell K, Sznajder JI, Budinger S. "Laminin-6 assembles into multimolecular fibrillar complexes with perlecan and participates in mechanical-signal transduction via a dystroglycan-dependent, integrin-independent mechanism." Journal of cell science.. 2005 Jun 15; 118(Pt 12):2557-66. Epub 2005 May 31.
6/2005
Dean DA, Strong DD, Zimmer WE. "Nuclear entry of nonviral vectors." Gene therapy.. 2005 Jun; 12(11):881-90.
2/1/2005
Machado-Aranda D, Adir Y, Young JL, Briva A, Budinger GR, Yeldandi AV, Sznajder JI, Dean DA. "Gene transfer of the Na+,K+-ATPase beta1 subunit using electroporation increases lung liquid clearance." American journal of respiratory and critical care medicine.. 2005 Feb 1; 171(3):204-11. Epub 2004 Oct 29.
1/2005
Wang L, Dean DA, Macdonald RC. "Effect of vinblastine on transfection: influence of cell types, cationic lipids and promoters." Current drug delivery.. 2005 Jan; 2(1):93-6.
11/2004
Zhou R, Geiger RC, Dean DA. "Intracellular trafficking of nucleic acids." Expert opinion on drug delivery.. 2004 Nov; 1(1):127-40.
4/2004
Zhang G, Gao X, Song YK, Vollmer R, Stolz DB, Gasiorowski JZ, Dean DA, Liu D. "Hydroporation as the mechanism of hydrodynamic delivery." Gene therapy.. 2004 Apr; 11(8):675-82.
12/2003
Dean DA. "Electroporation of the vasculature and the lung." DNA and cell biology.. 2003 Dec; 22(12):797-806.
11/2003
Nunamaker EA, Zhang HY, Shirasawa Y, Benoit JN, Dean DA. "Electroporation-mediated delivery of catalytic oligodeoxynucleotides for manipulation of vascular gene expression." American journal of physiology. Heart and circulatory physiology.. 2003 Nov; 285(5):H2240-7. Epub 2003 Jul 24.
9/2003
Dean DA, Machado-Aranda D, Blair-Parks K, Yeldandi AV, Young JL. "Electroporation as a method for high-level nonviral gene transfer to the lung." Gene therapy.. 2003 Sep; 10(18):1608-15.
8/2003
Young JL, Benoit JN, Dean DA. "Effect of a DNA nuclear targeting sequence on gene transfer and expression of plasmids in the intact vasculature." Gene therapy.. 2003 Aug; 10(17):1465-70.
6/16/2003
Gasiorowski JZ, Dean DA. "Mechanisms of nuclear transport and interventions." Advanced drug delivery reviews.. 2003 Jun 16; 55(6):703-16.
6/16/2003
Munkonge FM, Dean DA, Hillery E, Griesenbach U, Alton EW. "Emerging significance of plasmid DNA nuclear import in gene therapy." Advanced drug delivery reviews.. 2003 Jun 16; 55(6):749-60.
5/1/2003
Shirasawa Y, Rutland TJ, Young JL, Dean DA, Joseph BN. "Modulation of protein kinase C (PKC)-mediated contraction and the possible role of PKC epsilon in rat mesenteric arteries." Frontiers in bioscience : a journal and virtual library.. 2003 May 1; 8:a133-8. Epub 2003 May 01.
4/2003
Taylor W, Gokay KE, Capaccio C, Davis E, Glucksberg M, Dean DA. "The effects of cyclic stretch on gene transfer in alveolar epithelial cells." Molecular therapy : the journal of the American Society of Gene Therapy.. 2003 Apr; 7(4):542-9.
5/3/2002
Budinger GR, Tso M, McClintock DS, Dean DA, Sznajder JI, Chandel NS. "Hyperoxia-induced apoptosis does not require mitochondrial reactive oxygen species and is regulated by Bcl-2 proteins." The Journal of biological chemistry.. 2002 May 3; 277(18):15654-60. Epub 2002 Feb 27.
2/22/2002
Hirschi KK, Lai L, Belaguli NS, Dean DA, Schwartz RJ, Zimmer WE. "Transforming growth factor-beta induction of smooth muscle cell phenotpye requires transcriptional and post-transcriptional control of serum response factor." The Journal of biological chemistry.. 2002 Feb 22; 277(8):6287-95. Epub 2001 Dec 11.
1/2002
Young JL, Dean DA. "Nonviral gene transfer strategies for the vasculature." Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2002 Jan; 9(1):35-49.
2002
Blair-Parks K, Weston BC, Dean DA. "High-level gene transfer to the cornea using electroporation." The journal of gene medicine.. 2002 4(1):92-100.
2002
Filmore RA, Dean DA, Zimmer WE. "The smooth muscle gamma-actin gene is androgen responsive in prostate epithelia." Gene expression.. 2002 10(5-6):201-11.
5/1/2001
Dean DA, Perkin RA. "Gene therapy: if at first you don't succeed..." American family physician.. 2001 May 1; 63(9):1707, 1710, 1715-6.
3/2001
Li S, MacLaughlin FC, Fewell JG, Gondo M, Wang J, Nicol F, Dean DA, Smith LC. "Muscle-specific enhancement of gene expression by incorporation of SV40 enhancer in the expression plasmid." Gene therapy.. 2001 Mar; 8(6):494-7.
2001
Dean DA, Urban G, Aragon IV, Swingle M, Miller B, Rusconi S, Bueno M, Dean NM, Honkanen RE. "Serine/threonine protein phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling." BMC cell biology.. 2001 2:6. Epub 2001 May 17.
11/15/2000
Dean DA. "Peptide nucleic acids: versatile tools for gene therapy strategies." Advanced drug delivery reviews.. 2000 Nov 15; 44(2-3):81-95.
11/2000
Norwood N, Moore TM, Dean DA, Bhattacharjee R, Li M, Stevens T. "Store-operated calcium entry and increased endothelial cell permeability." American journal of physiology. Lung cellular and molecular physiology.. 2000 Nov; 279(5):L815-24.
4/2000
Bustamante JO, Michelette ER, Geibel JP, Hanover JA, McDonnell TJ, Dean DA. "Dendrimer-assisted patch-clamp sizing of nuclear pores." Pflu?gers Archiv : European journal of physiology.. 2000 Apr; 439(6):829-37.
2/2000
Bustamante JO, Michelette ER, Geibel JP, Dean DA, Hanover JA, McDonnell TJ. "Calcium, ATP and nuclear pore channel gating." Pflu?gers Archiv : European journal of physiology.. 2000 Feb; 439(4):433-44.
2000
Martin JB, Young JL, Benoit JN, Dean DA. "Gene transfer to intact mesenteric arteries by electroporation." Journal of vascular research.. 2000 37(5):372-80.
12/15/1999
Dean DA, Dean BS, Muller S, Smith LC. "Sequence requirements for plasmid nuclear import." Experimental cell research.. 1999 Dec 15; 253(2):713-22.
11/1999
Reddy JA, Dean D, Kennedy MD, Low PS. "Optimization of folate-conjugated liposomal vectors for folate receptor-mediated gene therapy." Journal of pharmaceutical sciences.. 1999 Nov; 88(11):1112-8.
7/30/1999
Wilson GL, Dean BS, Wang G, Dean DA. "Nuclear import of plasmid DNA in digitonin-permeabilized cells requires both cytoplasmic factors and specific DNA sequences." The Journal of biological chemistry.. 1999 Jul 30; 274(31):22025-32.
7/1/1999
Wang G, Xu X, Pace B, Dean DA, Glazer PM, Chan P, Goodman SR, Shokolenko I. "Peptide nucleic acid (PNA) binding-mediated induction of human gamma-globin gene expression." Nucleic acids research.. 1999 Jul 1; 27(13):2806-13.
7/1999
Dean DA, Byrd JN, Dean BS. "Nuclear targeting of plasmid DNA in human corneal cells." Current eye research.. 1999 Jul; 19(1):66-75.
6/1999
Vacik J, Dean BS, Zimmer WE, Dean DA. "Cell-specific nuclear import of plasmid DNA." Gene therapy.. 1999 Jun; 6(6):1006-14.
4/25/1998
Tran MT, Dean DA, Lausch RN, Oakes JE. "Membranes of herpes simplex virus type-1-infected human corneal epithelial cells are not permeabilized to macromolecules and therefore do not release IL-1alpha." Virology.. 1998 Apr 25; 244(1):74-8.
2/1/1997
Dean DA. "Import of plasmid DNA into the nucleus is sequence specific." Experimental cell research.. 1997 Feb 1; 230(2):293-302.
2/1995
Dean DA, Li PP, Lee LM, Kasamatsu H. "Essential role of the Vp2 and Vp3 DNA-binding domain in simian virus 40 morphogenesis." Journal of virology.. 1995 Feb; 69(2):1115-21.
2/18/1994
Dean DA, Kasamatsu H. "Signal- and energy-dependent nuclear transport of SV40 Vp3 by isolated nuclei. Establishment of a filtration assay for nuclear protein import." The Journal of biological chemistry.. 1994 Feb 18; 269(7):4910-6.
10/5/1993
Clever J, Dean DA, Kasamatsu H. "Identification of a DNA binding domain in simian virus 40 capsid proteins Vp2 and Vp3." The Journal of biological chemistry.. 1993 Oct 5; 268(28):20877-83.
8/1992
Dean DA, Hor LI, Shuman HA, Nikaido H. "Interaction between maltose-binding protein and the membrane-associated maltose transporter complex in Escherichia coli." Molecular microbiology.. 1992 Aug; 6(15):2033-40.
12/5/1990
Dean DA, Reizer J, Nikaido H, Saier MH. "Regulation of the maltose transport system of Escherichia coli by the glucose-specific enzyme III of the phosphoenolpyruvate-sugar phosphotransferase system. Characterization of inducer exclusion-resistant mutants and reconstitution of inducer exclusion in proteoliposomes." The Journal of biological chemistry.. 1990 Dec 5; 265(34):21005-10.
1990
Dean DA, Davidson AL, Nikaido H. "The role of ATP as the energy source for maltose transport in Escherichia coli." Research in microbiology. 1990 141(3):348-52.
12/1989
Dean DA, Davidson AL, Nikaido H. "Maltose transport in membrane vesicles of Escherichia coli is linked to ATP hydrolysis." Proceedings of the National Academy of Sciences of the United States of America.. 1989 Dec; 86(23):9134-8.
1/1989
Dean DA, Fikes JD, Gehring K, Bassford PJ, Nikaido H. "Active transport of maltose in membrane vesicles obtained from Escherichia coli cells producing tethered maltose-binding protein." Journal of bacteriology.. 1989 Jan; 171(1):503-10.