Collynn Woeller, Ph.D.

Contact Information

Faculty Appointments

Assistant Professor - Department of Ophthalmology (SMD)
Assistant Professor - Department of Environmental Medicine (SMD) - Joint

Biography

Research

Dr. Woeller's current research interest is understanding the key molecular and cellular pathways involved in eye disease, with a particular focus on Thyroid Eye Disease (TED). In TED a degenerative autoimmune response results in the formation of unwanted scar tissue behind the eye. This can cause cosmetic disfigurement resulting in double vision, eyelid retraction and, in some cases, blindness related to excess pressure on the optic nerve. Woeller and his collaborators have already discovered and patented promising new therapies that may arrest this process and could be used in treating diseases that manifest with excessive scar formation and/or excessive fat tissue, like TED. Woeller also has interests related to other vision disorders and the effect of environmental exposures (like airborne contaminants) on the eyes.

Woeller has authored, or co-authored, nearly 50 publications in scientific journals and Is a primary investigator or co-investigator om multiple grants from the National Institute’s for health and other funding sources.

Credentials

Education

2001
B.Sc. | SUNY Geneseo
Biochemistry

2007
Ph.D. | Cornell University
Biochemistry, Cellular and Molecular Biology

Post-doctoral Training & Residency

2009 - 2011
University of Rochester, Dept. of Environmental Medicine

2007 - 2009
University of Rochester, Dept of Biochemistry and Biophysics

Awards

2008 - 2009
F32 Postdoctoral Fellowship
Sponsor: Ruth L. Kirschstein National Research Service Award (NRSA)

2004
Experimental Biology Annual Meeting Graduate Student Research Award
Sponsor: ASNS/Procter & Gamble
Location: Washington DC

2004
Experimental Biology Gene-nutrient interaction RIS Student ward
Location: Washington, DC

2001
Jackson-Ulmer Award Biochemistry Graduate
Sponsor: SUNY Geneseo, Dept. of Chemistry

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Patents

Patent Title: Thy-1 (CD90) As a Novel Therapy to Control Adipose Tissue Accumulation
Patent #: 2908853
Issue Date: Dec 05, 2018
Country: Europe
Invented By: Steven E Feldon, Richard P Phipps, Collynn F Woeller

Patent Title: Thy-1 (CD90) As a Novel Therapy to Control Adipose Tissue Accumulation
Patent #: FR2908853
Issue Date: Dec 05, 2018
Country: France
Invented By: Steven E Feldon, Richard P Phipps, Collynn F Woeller

Patent Title: Thy-1 (CD90) As a Novel Therapy to Control Adipose Tissue Accumulation
Patent #: 602013047940.2
Issue Date: Dec 05, 2018
Country: Germany
Invented By: Steven E Feldon, Richard P Phipps, Collynn F Woeller

Patent Title: Thy-1 (CD90) As a Novel Therapy to Control Adipose Tissue Accumulation
Patent #: GB2908853
Issue Date: Dec 05, 2018
Country: United Kingdom
Invented By: Steven E Feldon, Richard P Phipps, Collynn F Woeller

Patent Title: Thy-1 (CD90) As a Novel Therapy to Control Adipose Tissue Accumulation
Patent #: 9,694,050
Issue Date: Jul 04, 2017
Country: United States
Invented By: Steven E Feldon, Richard P Phipps, Collynn F Woeller

Patent Title: Small Molecule Anti-Scarring Agents
Patent #: 10,548,911
Issue Date: Feb 04, 2020
Country: United States
Invented By: Richard P Phipps, Collynn F Woeller

Patent Title: Hernia Repair Device and Methods
Patent #: 10,285,794
Issue Date: May 14, 2019
Country: United States
Invented By: Lipton Laverne Martin, Richard P Phipps, Collynn F Woeller, E. Aubrey Woodroof

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Publications

Journal Articles

10/1/2019
Woeller CF, Roztocil E, Hammond C, Feldon SE. "TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts." Investigative ophthalmology & visual science.. 2019 Oct 1; 60(13):4336-4345.

3/2019
Flores EM, Woeller CF, Falsetta ML, Susiarjo M, Phipps RP. "Thy1 (CD90) expression is regulated by DNA methylation during adipogenesis." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2019 Mar 0; 33(3):3353-3363. Epub 2018 Oct 30.

2/10/2019
Thatcher TH, Woeller CF, McCarthy CE, Sime PJ. "Quenching the fires: Pro-resolving mediators, air pollution, and smoking." Pharmacology & therapeutics.. 2019 Feb 10; Epub 2019 Feb 10.

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