Research Bio
My research is practically driven, a combination of active collaborations in HIV, Influenza, and other diseases and independent research. In summary it falls in three areas: statistical processing of assay data (e.g., Elispot, Elisa, Hemagglutination assays), mixed-effect models for correlated data, and variable selection for high dimensional data.
2013
Yang H, Topham DJ, Holden-Wiltse J, Wu H. "Statistical estimation & inference of cell counts from ELISPOT limiting dilution assays." Journal of biopharmaceutical statistics. 2013 23(4):921-36. |
2012
Yang, H.; Topham, D.J.; Holden-Wiltse, J. and Wu, H. "Statistical Estimation & Inference of Cell Counts from ELISPOT Limiting Dilution Assays". Journal of Biopharmaceutical Statistics. 2012; . Link |
2012
Sundararajan A, Huan L, Richards KA, Marcelin G, Alam S, Joo H, Yang H, Webby RJ, Topham DJ, Sant AJ, Sangster MY. "Host differences in influenza-specific CD4 T cell and B cell responses are modulated by viral strain and route of immunization." PloS one. 2012 7(3):e34377. Epub 2012 Mar 23. |
2012
Henn AD, Laski M, Yang H, Welle S, Qiu X, Miao H, Barry CT, Wu H, Zand MS. "Functionally Distinct Subpopulations of CpG-Activated Memory B Cells." Scientific reports.. 2012 2:345. Epub 2012 Mar 30. |
2011 Apr 15
Quách TD, Manjarrez-Orduño N, Adlowitz DG, Silver L, Yang H, Wei C, Milner EC, Sanz I. "Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM." The Journal of immunology : official journal of the American Association of Immunologists.. 2011 Apr 15; 186(8):4640-8. Epub 2011 Mar 11. |
