Alan M. Grossfield, Ph.D.

Contact Information

Phone Numbers

Research Labs

My lab's research is focused on understanding the atomic-level interactions that drive the function of membranes and membrane proteins, using computer simulation as our primary tool.

Visit My lab's research is focused on understanding the atomic-level interactions that drive the function of membranes and membrane proteins, using computer simulation as our primary tool. Lab Website

Locations

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 712
Rochester, NY 14642

Faculty Appointments

Associate Professor - Department of Biochemistry and Biophysics (SMD)

Biography

Research

My research interests revolve around the use of computer modeling to understand the structure and thermodynamics of biological molecules. In particular, I am most interested in understanding the biology and physics of lipid-protein interactions. These interactions underlie a fantastic array of biological processes, including cell-signaling by GPCRs and some immune reactions, specifically the action of antimicrobial peptides.

Publications

Journal Articles

2/10/2023
Robinson EN, Grossfield A. "Application of molecular dynamics to elucidate key binding interactions for the development of therapeutics against opioid overdose." Biophysical journal.. 2023 Feb 10; 122(3S1):183a.

2/10/2023
Menon CSK, Karpos K, Grant TD, Struts AV, Fried SDE, Perera SMDC, Kosheleva IV, Salas-Estrada L, Grossfield A, Fromme P, Kirian RA, Brown MF. "X-ray scattering exhibits time-resolved view of rhodopsin activation." Biophysical journal.. 2023 Feb 10; 122(3S1):191a.

2/10/2023
Brown MF, Grant TD, Perera SMDC, Salas-Estrada L, Struts AV, Karpos K, Chawla U, Fried SDE, Menon CSK, Weerasinghe N, Meza D, Mendez D, Grossfield A, Fromme P, Kirian RA. "Femtosecond dynamics of rhodopsin revealed by X-ray laser." Biophysical journal.. 2023 Feb 10; 122(3S1):199a.

VIEW ALL PUBLICATIONS