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Christopher L. Seplaki, Ph.D.

Contact Information

Phone Numbers

Administrative: (585) 275-8784

Office: (585) 273-1549

Fax: (585) 461-4532

Faculty Appointments



Dr. Seplaki's overarching goals are to understand how challenges in the social and physical environment interact with the biological processes of aging, and how to translate that understanding into effective interventions that reduce disability and mortality among older adults. His research, spanning both the individual and population level, encompasses physical and social characteristics of the home environment that support or challenge elders, life stressors, and socioeconomic status, and examines how these factors are related to changes in biological indicators of several physiological systems and self-reports of physical and mental health. Key themes in his work include an emphasis on measurement and estimation issues and a focus on subclinical disease processes related to geriatric frailty and allostatic load, including development of measures of health risk related to multi-system dysregulation. Taken together, Dr. Seplaki's research seeks to provide an integrated perspective on trajectories of health in late life and, ultimately, identify opportunities to reduce disability and mortality and improve the ability of older adults to continue to live independently.

Keywords: Aging, disability, environment, frailty, biomarkers, measurement, health disparities



BA | Rutgers University

MS | Univ Wisconsin-Madison

PhD | Univ Wisconsin-Madison
Population Health


2014 - 2015
University of Rochester, Strategic Plan Pilot Grant in Aging Research, 2014-2015

Behavioral and Social Sciences Section
Sponsor: Gerontological Association of America

Mason F. Lord Poster Competition Honoring Dr. James Fries
Location: Johns Hopkins School of Medicine, Division of Geriatrics

RAND Summer Institute Full Scholarship

Conference Student Competition, Highly Commended
Location: International Health Economics Association

Conference Pre- and Post Doctoral Poster Award
Location: Association for Health Services Research

Distinguished Teaching Assistant
Location: Department of Economics, University of Wisconsin-Madison

Rutgers Scholar

John C. Daniel Memorial Award, Economics

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Journal Articles

Wolf DA; VA Freedman; JI Ondrich; CL Seplaki; BC Spillman. "Reply. Journals of Gerontology B: Social Sciences. [Epub ahead of print] April 1, 2015. PMCID Pending. Wolf, DA; VA Freedom; JL Ondrich; CL Seplaki; BC Spillman. "Disability Trajectories At The End Of Life: A Countdown Model." Journals of Gerontology B: Social Sciences. 2015; : [Epub ahead of print] PMCID Pending." Journals of Gerontology B: Social Sciences. 2015; .

Seplaki CL, Agree EM, Weiss CO, Szanton SL, Bandeen-Roche K, Fried LP. "Assistive devices in context: cross-sectional association between challenges in the home environment and use of assistive devices for mobility." The Gerontologist.. 2014 Aug 0; 54(4):651-60. Epub 2013 Apr 24.

Treviño LA†, L Baker, S McIntosh, K Mustian, CL Seplaki, JJ Guido, & DJ Ossip. ""Physical Activity as a Coping Strategy for Smoking Cessation in Mid-Life and Older Adults."". Addictive Behaviors. 2014; : May 2014; 39(5):885-8. Epub 2014 Feb 4. PMCID: PMC3999960.

Books & Chapters

Chapter Title: Reversing the impact of SES disparities over the life course on cognitive and brain aging
Book Title: The Biological Consequences of Socioeconomic Inequalities
Author List: Carlson MC, CL Seplaki, TE Seeman
Edited By: B. Wolfe, W. Evans & T. E. Seeman
Published By: Russell Sage Foundation 2012 in New York

Chapter Title: Frailty and Robustness
Book Title: Encyclopedia of the Life Course and Human Development
Author List: Seplaki, CL; Szanton, SL
Edited By: Deborah Carr
Published By: Macmillan Reference USA 2009 in Detroit

Chapter Title: Variation in Living Environments Among Community-Dwelling Elders
Book Title: Office of Population Research Working Paper Series
Author List: Seplaki CL, MA Smith, BH Singer
Published By: Princeton 2004 in Princeton University