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Yan Victoria Zhang, Ph.D.

Contact Information

Phone Numbers

Office: (585) 276-4192

Faculty Appointments


Professional Background

Victoria Zhang, PhD, MBA, has one foot planted in strategic planning and the other in the real world trenches of clinical lab operations. As the Vice Chair for Clinical Enterprise Strategy, she is focused on developing a vision for standardization and efficiency across all entities within the UR Medicine network. This includes an ever-evolving plan to expand that same network and develop sustainable strategies to support this growth.

"I think people in this region deserve the same quality of care and clinical expertise as those in Rochester. That's the vision of the Enterprise," she said.

While actively manifesting this vision to reality, Zhang has her other foot planted firmly in the lab where she is the Director of the Clinical Mass Spectrometry and Toxicology lab, and Associate Director of Clinical Chemistry. Being involved in the trenches with the front line staff has helped her continuously appreciate the daily challenges of clinical operations, and inform her long-term vision for the Enterprise.

Zhang came to the U.S. after studying Microbiology and Engineering at the Chinese Academy of Sciences and Tsinghua University. She earned her PhD in Biochemistry and Bioinformatics from the University of Minnesota specializing in proteomics and biomarker discovery. Combining her interests in healthcare and translational research, she then pursued her Clinical Chemistry Fellowship at Harvard Medical School to make a direct impact on patient care. Inspired to be an effective leader, she later earned her MBA from the Wharton School.

Since Zhang joined the faculty at URMC in 2011, she has taken on key leadership responsibilities both within the department and in national and international organizations. She is the Past Chair and Treasurer of the American Association for Clinical Chemistry (AACC) regional section and the Past President and Advisor of the North American Chinese Clinical Chemists Association (NACCCA).

Zhang was the Founding Chair who spearheaded the effort to create a new AACC division called Mass Spectrometry and Separation Sciences. She represented the AACC to deliver public comments regarding laboratory developed tests oversight issues to the FDA and was invited as the sole official Clinical Chemist representative on the "Cancer Moonshot" APOLLO Project Technology Working Group. Zhang is currently the Founding Faculty Chair of the AACC Asian Pacific Working group, an international lab quality initiative.

All of this experience in leading national and international programs has equipped her to take on the challenge of spurring growth and integration across the healthcare system as the Vice Chair for Clinical Enterprise. As she explains, teams within the clinical enterprise have complementary functions and talents. Pathologists and medical directors at the affiliated hospitals use their broad knowledge and an intimate understanding of the local community to serve their unique needs. The flagship medical center has experts who continuously develop cutting-edge technologies and best practices to provide in-depth insights into specialized clinical services. Working together, she envisions a wide-reaching service that allows everyone within the Enterprise to benefit.

"The ultimate goal of the lab Enterprise is to have an integrated and synergistic system to serve our patients and enable UR Medicine to become the care of choice in this region."

Outside of work, Victoria is experienced in mixed martial arts, ballroom dance and likes to collect stuffed animals from the conferences she attends around the world. She enjoys watching historical biographies, animated movies and nerdy TV shows like The Big Bang Theory. Her personal motto is "For all the things you do in life, do it like you mean it!"


Dr. Zhang has more than 15 years' experience in transnational research in biomarker discovery and clinical diagnostics. Her graduate school training in proteomics and bioinformatics provided her a solid foundation for applications of mass spectrometry for complex proteome analysis and her fellowship training in clinical chemistry provided her expertise in clinical understanding of in vitro diagnosis.

Dr. Zhang is the leading expert in mass spectrometry in clinical applications. She is the Founding Chair of the AACC Mass Spectrometry and Separation Sciences (MSSS) division and she grew the MSSS to over 400 members nationally within 3 years to become the leading resources for clinical mass spectrometry applications. Dr. Zhang is the faculty Chair of two online certificate programs for mass spectrometry, spearheaded the national mass spectrometry workshops during AACC and AACC/MSSS annual conferences. She has been on and Chaired several national and international conferences on clinical mass spectrometry and laboratory medicine. She was invited as the sole official clinical chemist representative on the "Cancer Moonshot" APOLLO Technology Working group. She is now on the CLSI committee to develop guidelines for targeted mass spectrometry assays for proteins and peptides.

Dr. Zhang is also interested in lab test utilization and how to use different tools particularly laboratory formulary to guide proper usage of lab tests to best serve the patient needs and improve efficiency for lab tests in healthcare as a whole.

She has published over 50 peer-reviewed articles and book chapters, more than 15 other journal publication, over 90 podium presentations including more than 50 national and international invited presentations, and over a dozen media reports and interviews. Dr. Zhang has been on organizing committee for nearly 20 regional and national conferences with similar number of international and national symposia, workshops and short courses. She is on several the Editorial Boards in the field of clinical chemistry and laboratory medicine.



PhD | University of Minnesota
Biochemistry and Bioinformatics

Fellowship | Harvard Medical School

MBA | The Wharton School, University of Pennsylvania

Post-doctoral Training & Residency

10/2006 - 10/2008
Post-doctoral Research Associate, University of Minnesota, Medical School, Department of Biochemistry, Molecular Biology and Biophysics


2017 - Present
Outstanding Leadership Award, Wallace H Coulter Foundation and AACC
Sponsor: For leadership in designing, organizing, and delivering the Glob

2017 - Present
Excellence in Education Award, AACC MSSS Division
Sponsor: For contributions and leadership for online educations for clini

2017 - Present
Outstanding Speaker Award, AACC
Sponsor: Based on audience evaluation among all speakers for AACC continu

2017 - 2017
Founders Award, American Association for Clinical Chemistry (AACC)
Sponsor: For dedication and leadership in establishing the AACC MSSS Divi

2017 - 2017
Director's List, the Wharton School
Sponsor: For top 10% academic performance
Location: University of Pennsylvania

AACC Outstanding Speaker Award
Sponsor: American Association for Clinical Chemistry

AACC Research Grant Award
Sponsor: American Association for Clinical Chemistry

2014 - Present
Founding Chair, Mass Spectrometry and Separation Sciences Division, AACC

2014 - Present
Chair, Upstate New York Local Section, AACC

2014 - Present
President, North American Chinese Clinical Chemistry Association

Young Investigator Award
Sponsor: Association for Mass Spec (MSACL)

Laboratory Director Award
Sponsor: Association for Mass Spec (MSACL)

Domestic Travel Grant from Society for Young Clinical Laboratorians (SYCL)
Sponsor: Van Slyke Foundation

Cyrus P. and Anne R. Barnum Travel Award
Sponsor: Minnesota Medical Foundation
Location: ASMS Conference, University of Minnesota

2006 - 2017
Cyrus P. and Anne R. Barnum Travel Award
Sponsor: Minnesota Medical Foundation
Location: 5th HUPO Conference, University of Minnesota

Excellent Leadership Award
Sponsor: Chinese Academy of Sciences

Summa Cum Laude
Sponsor: Shandong University

1995 - 1998
First Prize Scholarship
Sponsor: Shandong University

1994 - 1998
Excellent Leadership Award
Sponsor: Shandong University

1994 - 1998
Excellent Student Award
Sponsor: Shandong University

1994 - 1995
Second Prize Scholarship
Sponsor: Shandong University

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Journal Articles

Zhang YV, Fan SL, Kellogg MD. "Effect of hemolysis, icterus, and lipemia on three acetaminophen assays: Potential medical consequences of false positive results." Clinica chimica acta; international journal of clinical chemistry.. 2018 Oct 11; 487:287-292. Epub 2018 Oct 11.

Jackson TC, Zhang YV, Sime PJ, Phipps RP, Kottmann RM. "Development of an accurate and sensitive method for lactate analysis in exhaled breath condensate by LC MS/MS." Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.. 2017 Sep 1; 1061-1062:468-473. Epub 2017 Jul 24.

Zhang YV, Smoller BR, Levy PC. "Laboratory Formulary: A Model for High-Value Evidence-Based Medicine." Clinical chemistry.. 2017 Jul 0; 63(7):1299-1300. Epub 2017 May 17.

Books & Chapters

Chapter Title: LC-MS/MS as Emerging Technique in Toxicology Laboratory
Book Title: Clinical Toxicology
Author List: Zhang, Y.V., Wei, B., Zhu, Y., Zhang, Y.H.
Edited By: Editor, Martin Bluth
Published By: - 2016

Chapter Title: Principles f Laboratory Management
Book Title: Comtemporary Practice in Clinical Chemistry
Author List: Zhang, Y.V.
Edited By: Submitted, Editors: William Clarke and D. Robert Dufour
Published By: - 2016

Chapter Title: Mass Spectrometry in Clinical Laboratory: Applications in Biomolecular Analysis
Book Title: Clinical Applications of Mass Spectrometry in Biomolecular Analysis
Author List: Garg, U., Zhang, Y.V.
Edited By: Editor, Uttam Garg
Published By: - 2016