Skip to main content

Coronavirus (COVID-19): Visitor Restrictions, Resources, and Updates

Explore URMC

Eric M. Small, Ph.D.


Showing all 40 journal articles & 0 books available

Journal Articles

Quijada P, Trembley MA, Small EM. "The Role of the Epicardium During Heart Development and Repair." Circulation research.. 2020 Jan 31; 126(3):377-394. Epub 2020 Jan 30.

Chen S, Zhang Y, Lighthouse JK, Mickelsen DM, Wu J, Yao P, Small EM, Yan C. "A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction." Circulation.. 2019 Dec 5; Epub 2019 Dec 05.

Liu H, Zhang S, Xu S, Koroleva M, Small EM, Jin ZG. "Myofibroblast-specific YY1 promotes liver fibrosis." Biochemical and biophysical research communications.. 2019 Jun 30; 514(3):913-918. Epub 2019 May 10.

Burke RM, Lighthouse JK, Mickelsen DM, Small EM. "Sacubitril/Valsartan Decreases Cardiac Fibrosis in Left Ventricle Pressure Overload by Restoring PKG Signaling in Cardiac Fibroblasts." Circulation. Heart failure.. 2019 Apr 0; 12(4):e005565.

Quijada P, Misra A, Velasquez LS, Burke RM, Lighthouse JK, Mickelsen DM, Dirkx RA, Small EM. "Pre-existing fibroblasts of epicardial origin are the primary source of pathological fibrosis in cardiac ischemia and aging." Journal of molecular and cellular cardiology.. 2019 Feb 13; 129:92-104. Epub 2019 Feb 13.

Hilt ZT, Pariser DN, Ture SK, Mohan A, Quijada P, Asante A, Cameron SJ, Sterling JA, Merkel AR, Johanson AL, Jenkins JL, Small EM, McGrath KE, Palis J, Elliott MR, Morrell CN. "Platelet-derived ?2M regulates monocyte inflammatory responses." JCI insight.. 2019 Jan 31; Epub 2019 Jan 31.

Lighthouse JK, Burke RM, Velasquez LS, Dirkx RA, Aiezza A, Moravec CS, Alexis JD, Rosenberg A, Small EM. "Exercise promotes a cardioprotective gene program in resident cardiac fibroblasts." JCI insight.. 2019 Jan 10; 4(1)Epub 2019 Jan 10.

Chi C, Leonard A, Knight WE, Beussman KM, Zhao Y, Cao Y, Londono P, Aune E, Trembley MA, Small EM, Jeong MY, Walker LA, Xu H, Sniadecki NJ, Taylor MR, Buttrick PM, Song K. "LAMP-2B regulates human cardiomyocyte function by mediating autophagosome-lysosome fusion." Proceedings of the National Academy of Sciences of the United States of America.. 2019 Jan 8; 116(2):556-565. Epub 2018 Dec 24.

Trembley MA, Quijada P, Agullo-Pascual E, Tylock KM, Colpan M, Dirkx RA, Myers JR, Mickelsen DM, de Mesy Bentley K, Rothenberg E, Moravec CS, Alexis JD, Gregorio CC, Dirksen RT, Delmar M, Small EM. "Mechanosensitive Gene Regulation by Myocardin-Related Transcription Factors Is Required for Cardiomyocyte Integrity in Load-Induced Ventricular Hypertrophy." Circulation.. 2018 Oct 23; 138(17):1864-1878.

Lacy SH, Woeller CF, Thatcher TH, Pollock SJ, Small EM, Sime PJ, Phipps RP. "Activated Human Lung Fibroblasts Produce Extracellular Vesicles with Anti-Fibrotic Prostaglandins." American journal of respiratory cell and molecular biology.. 2018 Sep 28; Epub 2018 Sep 28.

Burke RM, Lighthouse JK, Quijada P, Dirkx RA, Rosenberg A, Moravec CS, Alexis JD, Small EM. "Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure." Proceedings of the National Academy of Sciences of the United States of America.. 2018 Apr 10; 115(15):E3436-E3445. Epub 2018 Mar 26.

Guo B, Lyu Q, Slivano OJ, Dirkx R, Christie CK, Czyzyk J, Hezel AF, Gharavi AG, Small EM, Miano JM. "Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function." Journal of the American Society of Nephrology : JASN.. 2018 Feb 0; 29(2):416-422. Epub 2017 Nov 07.

Cao J, Wang J, Jackman CP, Cox AH, Trembley MA, Balowski JJ, Cox BD, De Simone A, Dickson AL, Di Talia S, Small EM, Kiehart DP, Bursac N, Poss KD. "Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue." Developmental cell.. 2017 Sep 25; 42(6):600-615.e4.

Small EM, Burke RM. "?-Adrenergic Blockade in Ischemia-Reperfusion Injury: ?ARKing Up a New Tree." Journal of the American College of Cardiology.. 2017 Aug 22; 70(8):972-974.

Knight WE, Chen S, Zhang Y, Oikawa M, Wu M, Zhou Q, Miller CL, Cai Y, Mickelsen DM, Moravec C, Small EM, Abe J, Yan C. "PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction." Proceedings of the National Academy of Sciences of the United States of America.. 2016 Nov 8; 113(45):E7116-E7125. Epub 2016 Oct 20.

Trembley MA, Velasquez LS, Small EM. "Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration." Journal of visualized experiments : JoVE.. 2016 Mar 18; (109)Epub 2016 Mar 18.

Luna-Zurita L, Stirnimann CU, Glatt S, Kaynak BL, Thomas S, Baudin F, Samee MA, He D, Small EM, Mileikovsky M, Nagy A, Holloway AK, Pollard KS, Müller CW, Bruneau BG. "Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis." Cell.. 2016 Feb 25; 164(5):999-1014. Epub 2016 Feb 11.

Lighthouse JK, Small EM. "Transcriptional control of cardiac fibroblast plasticity." Journal of molecular and cellular cardiology.. 2016 Feb 0; 91:52-60. Epub 2015 Dec 22.

Trembley MA, Velasquez LS, de Mesy Bentley KL, Small EM. "Myocardin-related transcription factors control the motility of epicardium-derived cells and the maturation of coronary vessels." Development.. 2015 Jan 1; 142(1):21-30.

Rodés-Cabau J, Dauerman HL, Cohen MG, Mehran R, Small EM, Smyth SS, Costa MA, Mega JL, O'Donoghue ML, Ohman EM, Becker RC. "Antithrombotic treatment in transcatheter aortic valve implantation: insights for cerebrovascular and bleeding events." Journal of the American College of Cardiology.. 2013 Dec 24; 62(25):2349-2359. Epub 2013 Apr 10.

Velasquez LS, Sutherland LB, Liu Z, Grinnell F, Kamm KE, Schneider JW, Olson EN, Small EM. "Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing." Proceedings of the National Academy of Sciences of the United States of America.. 2013 Oct 15; 110(42):16850-5. Epub 2013 Sep 30.

Small EM. "The actin-MRTF-SRF gene regulatory axis and myofibroblast differentiation." Journal of cardiovascular translational research. 2012 Dec 0; 5(6):794-804. Epub 2012 Aug 17.

Miano JM, Small EM. "MicroRNA133a: a new variable in vascular smooth muscle cell phenotypic switching." Circulation research.. 2011 Sep 30; 109(8):825-7.

Small EM, Olson EN. "Pervasive roles of microRNAs in cardiovascular biology." Nature.. 2011 Jan 20; 469(7330):336-42.

Small EM, Sutherland LB, Rajagopalan KN, Wang S, Olson EN. "MicroRNA-218 regulates vascular patterning by modulation of Slit-Robo signaling." Circulation research.. 2010 Nov 26; 107(11):1336-44. Epub 2010 Oct 14.

Small EM, Thatcher JE, Sutherland LB, Kinoshita H, Gerard RD, Richardson JA, Dimaio JM, Sadek H, Kuwahara K, Olson EN. "Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction." Circulation research.. 2010 Jul 23; 107(2):294-304. Epub 2010 Jun 17.

Small EM, O'Rourke JR, Moresi V, Sutherland LB, McAnally J, Gerard RD, Richardson JA, Olson EN. "Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486." Proceedings of the National Academy of Sciences of the United States of America.. 2010 Mar 2; 107(9):4218-23. Epub 2010 Feb 08.

Small EM, Frost RJ, Olson EN. "MicroRNAs add a new dimension to cardiovascular disease." Circulation.. 2010 Mar 2; 121(8):1022-32.

Xin M, Small EM, Sutherland LB, Qi X, McAnally J, Plato CF, Richardson JA, Bassel-Duby R, Olson EN. "MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury." Genes & development.. 2009 Sep 15; 23(18):2166-78. Epub 2009 Aug 31.

Meadows SM, Warkman AS, Salanga MC, Small EM, Krieg PA. "The myocardin-related transcription factor, MASTR, cooperates with MyoD to activate skeletal muscle gene expression." Proceedings of the National Academy of Sciences of the United States of America.. 2008 Feb 5; 105(5):1545-50. Epub 2008 Jan 29.

Xin M, Small EM, van Rooij E, Qi X, Richardson JA, Srivastava D, Nakagawa O, Olson EN. "Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function." Proceedings of the National Academy of Sciences of the United States of America.. 2007 May 8; 104(19):7975-80. Epub 2007 Apr 27.

Small EM, Warkman AS, Wang DZ, Sutherland LB, Olson EN, Krieg PA. "Myocardin is sufficient and necessary for cardiac gene expression in Xenopus." Development.. 2005 Mar 0; 132(5):987-97. Epub 2005 Jan 26.

Small EM, Krieg PA. "Molecular regulation of cardiac chamber-specific gene expression." Trends in cardiovascular medicine.. 2004 Jan 0; 14(1):13-8.

Small EM, Krieg PA. "Transgenic analysis of the atrialnatriuretic factor (ANF) promoter: Nkx2-5 and GATA-4 binding sites are required for atrial specific expression of ANF." Developmental biology.. 2003 Sep 1; 261(1):116-31.

Small EM, Krieg PA. "Molecular mechanisms of chamber-specific myocardial gene expression: transgenic analysis of the ANF promoter." Cold Spring Harbor symposia on quantitative biology.. 2002 67:71-9.

Wang D, Passier R, Liu ZP, Shin CH, Wang Z, Li S, Sutherland LB, Small E, Krieg PA, Olson EN. "Regulation of cardiac growth and development by SRF and its cofactors." Cold Spring Harbor symposia on quantitative biology.. 2002 67:97-105.

Wang D, Chang PS, Wang Z, Sutherland L, Richardson JA, Small E, Krieg PA, Olson EN. "Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor." Cell.. 2001 Jun 29; 105(7):851-62.

Garriock RJ, Vokes SA, Small EM, Larson R, Krieg PA. "Developmental expression of the Xenopus Iroquois-family homeobox genes, Irx4 and Irx5." Development genes and evolution. 2001 May 0; 211(5):257-60.

Small EM, Krieg PA. "Expression of atrial natriuretic factor (ANF) during Xenopus cardiac development." Development genes and evolution. 2000 Dec 0; 210(12):638-40.

Small EM, Vokes SA, Garriock RJ, Li D, Krieg PA. "Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes." Mechanisms of development.. 2000 Sep 0; 96(2):259-62.