CONTACT INFORMATIONCREDENTIALSAWARDSPUBLICATIONSJennetta W. Hammond, Ph.D.Contact InformationPhone NumbersOffice: (585) 273-2872LocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 645Rochester, NY 14642Faculty AppointmentsAssistant Professor - Department of Neurology , Neuroimmunology (SMD) Assistant Professor - Department of Neuroscience (SMD) - JointBiographyResearchMy research interests are focused on uncovering neuro-immune mechanisms driving synapse and neuron turnover as well as microglia dysregulation throughout the lifespan. Most of my current projects focus on regulation of the complement pathway in the CNS. I have identified and begun characterizing novel complement inhibitory proteins that are specifically expressed in neurons, namely the Sez6 family and Srpx2. These complement inhibitors may serve as protective factors to preserve neurons and neuronal connections during critical windows in brain development when complement is engaged to prune away excess connections. These same complement inhibitors also appear to play a protective role in aging and are likely very important in pathological conditions with heightened inflammation and complement activation like multiple sclerosis.CredentialsEducation2002BS | Brigham Young UniversityZoology2008PhD | University of MichiganCell and Developmental BiologyPost-doctoral Training & Residency11/01/2012 - 01/31/2018University of Rochester Medical Center; Center for Neurotherapeutics Discovery. Advisor: Harris GelbardAwards2015Trainee Professional Development AwardSponsor: Society for NeurosciencePublicationsJournal Articles3/8/2021Urban JM, Chiang W, Hammond JW, Cogan NMB, Litzburg A, Burke R, Stern HA, Gelbard HA, Nilsson BL, Krauss TD. "Quantum Dots for Improved Single-Molecule Localization Microscopy." The journal of physical chemistry. B. 2021 Mar 8; Epub 2021 Mar 08. 2021Qiu WQ, Luo S, Ma SA, Saminathan P, Li H, Gunnersen JM, Gelbard HA, Hammond JW. "The Sez6 Family Inhibits Complement by Facilitating Factor I Cleavage of C3b and Accelerating the Decay of C3 Convertases." Frontiers in immunology.. 2021 12:607641. Epub 2021 Apr 15. 10/1/2020Nguyen L, Laboissonniere LA, Guo S, Pilotto F, Scheidegger O, Oestmann A, Hammond JW, Li H, Hyysalo A, Peltola R, Pattamatta A, Zu T, Voutilainen MH, Gelbard HA, Saxena S, Ranum LPW. "Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs." Neuron.. 2020 Oct 1; Epub 2020 Oct 01. VIEW ALL PUBLICATIONSClose WindowSchedule an appointment with Jennetta W. Hammond, Ph.D.Please answer the following questions to help us find the right appointment for you.Important: If you believe that you have a medical or psychiatric emergency, please call 911 or go to the nearest hospital. This website is not intended for emergency care.Have you seen this provider in the last 2 years?YesNoExisting Patient Schedule or request a follow up appointment online through MyChart. If you do not have a MyChart account, please close this window and call the appointment phone number. Jennetta W. Hammond, Ph.D. is currently scheduling for the following appointment type(s): Our policy does not permit patients to establish care with multiple providers within the same practice or specialty without prior approval. If you choose a new provider in the same office, we will cancel the appointment. Please contact the office directly with questions on this policy.