CONTACT INFORMATIONCREDENTIALSPUBLICATIONSAntti E. Seppo, Ph.D.Contact InformationLocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 777Rochester, NY 14642Faculty AppointmentsResearch Professor - Department of Pediatrics , Pediatric Allergy/Immunology (SMD) BiographyResearchMy short-term research interest is to develop an understanding of the factors that predispose and cause food allergies in children, and to understand predictive indicators of the severity of allergic reactions in children and adults. Understanding of the predisposing and causative factors will help to develop strategies to prevent allergies in children. My research aims to evaluate genetic factors by applying genomic and transcriptomic techniques and environment related factors by biochemical screening of biomarkers. Generating predictors of food allergy severity will enable better management of newly diagnosed food allergy patients. These predictors will be established by evaluating tests that measure aspects of humoral and cellular immune response in vitro, and selecting promising candidate markers for clinical evaluation. My long-term interest is to understand the fundamental mechanisms in the developing human immune system and particularly mechanisms that upon failure cause allergic disease. This understanding will in part come from observations in the studies of allergy relevant factors, and in part from mechanistic studies involving candidate pathways of early immune system development. Separate form allergy research my research interest also include integration of leading edge biocomputing methods into cell based assay research, especially in connection with image analysis.CredentialsEducation1996PhD | Finland-University of HelsinkiBiotechnologyPublicationsJournal Articles9/2022Davis EC, Castagna VP, Sela DA, Hillard MA, Lindberg S, Mantis NJ, Seppo AE, Järvinen KM. "Gut microbiome and breast-feeding: Implications for early immune development." The Journal of allergy and clinical immunology.. 2022 Sep; 150(3):523-534. 2020McGuire MK, Randall AZ, Seppo AE, Järvinen KM, Meehan CL, Gindola D, Williams JE, Sellen DW, Kamau-Mbuthia EW, Kamundia EW, Mbugua S, Moore SE, Prentice AM, Foster JA, Otoo GE, Rodríguez JM, Pareja RG, Bode L, McGuire MA, Campo JJ. "Multipathogen Analysis of IgA and IgG Antigen Specificity for Selected Pathogens in Milk Produced by Women From Diverse Geographical Regions: The INSPIRE Study." Frontiers in immunology.. 2020 11:614372. Epub 2021 Feb 11. 1/22/2019Seppo AE, Kukkonen AK, Kuitunen M, Savilahti E, Yonemitsu C, Bode L, Järvinen KM. "Association of Maternal Probiotic Supplementation With Human Milk Oligosaccharide Composition." JAMA pediatrics.. 2019 Jan 22; Epub 2019 Jan 22. VIEW ALL PUBLICATIONSClose WindowSchedule an appointment with Antti E. Seppo, Ph.D.Please answer the following questions to help us find the right appointment for you.Important: If you believe that you have a medical or psychiatric emergency, please call 911 or go to the nearest hospital. This website is not intended for emergency care.Have you seen this provider in the last 2 years?YesNoExisting Patient Schedule or request a follow up appointment online through MyChart. If you do not have a MyChart account, please close this window and call the appointment phone number. Antti E. Seppo, Ph.D. is currently scheduling for the following appointment type(s): Our policy does not permit patients to establish care with multiple providers within the same practice or specialty without prior approval. If you choose a new provider in the same office, we will cancel the appointment. Please contact the office directly with questions on this policy.