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Gowrishankar Muthukrishnan, Ph.D.

Contact Information

Phone Numbers

Office: (585) 273-5632

Social Links

@MuthukrishnanLab

Research Labs

Faculty Appointments

Biography

Professional Background

Gowrishankar Muthukrishnan earned his Ph.D. in Biomedical Sciences. He is a microbial immunologist with expertise in host-microbe interactions, bacterial pathogenesis, and immunobiology of Staphylococcus aureus infections. His graduate work aimed at understanding the S. aureus nasal carriage dynamics, in addition to identifying important host and microbial determinants that influence S. aureus nasal colonization in humans. His postdoctoral studies at the University of Rochester Medical Center involved numerous basic research projects related to human immune mechanisms and the development of supporting immunological methods for viral and bacterial vaccine research. He also worked on assessing functional humoral and cell-mediated responses in patients with S. aureus osteomyelitis, diabetic foot ulcer infections, and spine infections. As a faculty member within the Center for Musculoskeletal Research (CMSR), University of Rochester Medical Center, his research group is focused on understanding host-pathogen interactions and the osteoimmunology of orthopaedic infections. His research group is also developing novel small animal models (humanized mice) to study bone infections.

Credentials

Education

2007
Masters in Engineering | Birla Institute of Technology and Science, Pilani, India
Biotechnology

2010
MS | University of Central Florida
Molecular Biology and Microbiology

2014
PhD | University of Central Florida College of Medicine
Biomedical Sciences

Post-doctoral Training & Residency

2017 - 2019
Center for Musculoskeletal Research, Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center

2015 - 2017
Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center

Awards

2019 - 2021
AO Research Institute Fellowship (Davos, Switzerland)
Sponsor: AO Trauma

2016
Great Lakes International Imaging and Flow Cytometry Association (GLIIFCA 2016) Travel Award

2016
Great Lakes International Imaging and Flow Cytometry Association (GLIIFCA 2016) Best Poster Award

2011 - 2012
Rudy Wodzinski Memorial Scholarship

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Publications

Journal Articles

8/26/2022
Morita Y, Saito M, Rangel-Moreno J, Franchini AM, Owen JR, Martinez JC, Daiss JL, de Mesy Bentley KL, Kates SL, Schwarz EM, Muthukrishnan G. "Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation." Bone research.. 2022 Aug 26; 10(1):56. Epub 2022 Aug 26.

2/15/2022
Masters EA, Ricciardi BF, Bentley KLM, Moriarty TF, Schwarz EM, Muthukrishnan G. "Skeletal infections: microbial pathogenesis, immunity and clinical management." Nature reviews. Microbiology.. 2022 Feb 15; Epub 2022 Feb 15.

2/4/2022
Campbell MP, Mott MD, Owen JR, Reznicek JE, Beck CA, Muthukrishnan G, Golladay GJ, Kates SL. "Low albumin level is more strongly associated with adverse outcomes and Staphylococcus aureus infection than hemoglobin A1C or smoking tobacco." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2022 Feb 4; Epub 2022 Feb 04.

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