CONTACT INFORMATIONBIOGRAPHYCREDENTIALSPUBLICATIONSBin Zhang, Ph.D.Contact InformationPhone NumbersOffice: (585) 276-8707LocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 608Rochester, NY 14642Faculty AppointmentsAssistant Professor - Department of Pathology and Laboratory Medicine (SMD) BiographyProfessional BackgroundDr. Bin Zhang is an Assistant Professor in the Department of Pathology & Laboratory Medicine and the Department of Pediatrics at University of Rochester. He serves as a clinical genomicist in the cytogenetics laboratory at Strong Memorial Hospital. He earned his PhD in Molecular Genetics and Genomics and obtained his Clinical Genomics fellowship at Washington University in Saint Louis. He is board certified in Clinical Cytogenetics and board eligible in Clinical Molecular Genetics by the American Board of Medical Genetics and Genomics. Prior to his doctoral studies, he earned his BS in Biology from Sichuan University in China and MS in Biology from Truman State University. He also completed his post-doctoral training at Cold Spring Harbor Laboratory. Dr. Zhang' clinical responsibilities include the genetic diagnostic evaluation of blood, bone marrow, lymph nodes, amniotic fluid, chorionic villus, product of conception, and tissues for other malignancies. This includes interpretation of molecular genetics and cytogenetics data from sequencing, karyotyping, FISH and microarray analysis.ResearchHis graduate study focused on human genetics and mouse modeling of cohesinopathies, and his postdoctoral work on studying function, regulation, and evolution of long (MALAT1 and NEAT1) and small (piRNAs) non-coding RNAs (ncRNAs). He maintains active research interests in RNA-based disease biology, cancer biology, and biomarker discovery using genomic approaches. In particular, his research program at University of Rochester focuses on studying molecular and cellular functions of ncRNAs during tumoriogenesis, and developing novel NGS-based methodologies for efficient circulating tumor DNA (ctDNA) detection and nucleotide-level mapping of disease-associated chromosomal rearrangements.CredentialsEducation2007PhD | Washington University in Saint LouisPost-doctoral Training & Residency10/01/2012 - 09/30/2015Clinical Genomics Fellowship at Washington University in Saint Louis03/01/2009 - 09/30/2012Postdoctoral Fellowship at Cold Spring Harbor LaboratoryPublicationsJournal Articles2018Reyes-Barron C, Evans AG, Miyamoto H, Zhang B, Iqbal MA. "Novel 1.3 Mb germline duplication in chromosome 8q21.11 by microarray comparative genomic hybridization plus single nucleotide polymorphism analysis in an adult patient with pancytopenia and urinary bladder complications". Clinical Case Reports. 2018; 0(0): 1-6.6/2017Katzman PJ, Metlay LA, McMahon LA, LiQiong L, Zhang B. "Chorionic Histiocytic Hyperplasia is Associated With Chronic Inflammatory Lesions in the Placenta." Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.. 2017 Jun 0; 20(3):197-205. Epub 2017 Feb 08. 5/23/2017Zhang B, Mao YS, Diermeier SD, Novikova IV, Nawrocki EP, Jones TA, Lazar Z, Tung CS, Luo W, Eddy SR, Sanbonmatsu KY, Spector DL. "Identification and Characterization of a Class of MALAT1-like Genomic Loci." Cell reports.. 2017 May 23; 19(8):1723-1738. Books & Chapters2014 Chapter Title: Single Nucleotide Variant Detection Using Next Generation Sequencing Book Title: Clinical Genomics Author List: David H. Spencer, Bin Zhang and John Pfeifer Edited By: Shashikant Kulkarni and John Pfeifer Published By: Elsevier 2014VIEW ALL PUBLICATIONS