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Bin Zhang, Ph.D.

Contact Information

Phone Numbers

Office: (585) 276-8707

Faculty Appointments

Biography

Professional Background

Dr. Bin Zhang is an Associate Professor in the Department of Pathology & Laboratory Medicine and the Department of Pediatrics at University of Rochester. He serves as a clinical genomicist in the cytogenetics laboratory at Strong Memorial Hospital. He earned his PhD in Molecular Genetics and Genomics and obtained his Clinical Genomics fellowship at Washington University in Saint Louis. He is board certified in Clinical Cytogenetics and board eligible in Clinical Molecular Genetics by the American Board of Medical Genetics and Genomics. Prior to his doctoral studies, he earned his BS in Biology from Sichuan University in China and MS in Biology from Truman State University. He also completed his post-doctoral training at Cold Spring Harbor Laboratory.

Dr. Zhang' clinical responsibilities include the genetic diagnostic evaluation of blood, bone marrow, lymph nodes, amniotic fluid, chorionic villus, product of conception, and tissues for other malignancies. This includes interpretation of molecular genetics and cytogenetics data from sequencing, karyotyping, FISH and microarray analysis.

Research

His graduate study focused on human genetics and mouse modeling of cohesinopathies, and his postdoctoral work on the function, regulation, and evolution of long (MALAT1 and NEAT1) and small (piRNAs) non-coding RNAs (ncRNAs). He maintains active research interests in chromosome biology and centromere biology. In particular, his research program at University of Rochester focuses on the formation, plasticity, and epigenetic inheritance of neocentromere, and its potential clinical applications in gene therapy and synthetic biology.

Email address: bin_zhang@urmc.rochester.edu.

Credentials

Education

2007
PhD | Washington University in Saint Louis

Post-doctoral Training & Residency

10/01/2012 - 09/30/2015
Clinical Genomics Fellowship at Washington University in Saint Louis

03/01/2009 - 09/30/2012
Postdoctoral Fellowship at Cold Spring Harbor Laboratory

Publications

Journal Articles

6/11/2022
Shi Q, Zhang B, Bsirini C, Li L, Giampoli EJ, Magliocca KR, Reid M, Zhou Z. "NR4A3 Fluorescence In Situ Hybridization Analysis in Cytologic and Surgical Specimens of acinic cell carcinoma." Human pathology.. 2022 Jun 11; Epub 2022 Jun 11.

12/20/2021
Zhang B, Liu M, Fong CT, Iqbal MA. "MEIS2 (15q14) gene deletions in siblings with mild developmental phenotypes and bifid uvula: documentation of mosaicism in an unaffected parent." Molecular cytogenetics. 2021 Dec 20; 14(1):58. Epub 2021 Dec 20.

10/7/2021
Miller C, Gertsen BG, Schroeder AL, Fong CT, Iqbal MA, Zhang B. "Allelic and dosage effects of NHS in X-linked cataract and Nance-Horan syndrome: a family study and literature review." Molecular cytogenetics. 2021 Oct 7; 14(1):48. Epub 2021 Oct 07.

Books & Chapters

2014
Chapter Title: Single Nucleotide Variant Detection Using Next Generation Sequencing
Book Title: Clinical Genomics
Author List: David H. Spencer, Bin Zhang and John Pfeifer
Edited By: Shashikant Kulkarni and John Pfeifer
Published By: Elsevier 2014

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