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David M. MacLean, Ph.D.

Publications

Showing all 21 journal articles & 1 books available

Journal Articles

2/27/2018
Chen J, Li L, Chen SR, Chen H, Xie JD, Sirrieh RE, MacLean DM, Zhang Y, Zhou MH, Jayaraman V, Pan HL. "The ?2?-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions." Cell reports.. 2018 Feb 27; 22(9):2307-2321.

12/2017
Dolino DM, Chatterjee S, MacLean DM, Flatebo C, Bishop LDC, Shaikh SA, Landes CF, Jayaraman V. "The structure-energy landscape of NMDA receptor gating." Nature chemical biology.. 2017 Dec 0; 13(12):1232-1238. Epub 2017 Oct 09.

8/1/2017
Coombs ID, MacLean DM, Jayaraman V, Farrant M, Cull-Candy SG. "Dual Effects of TARP ?-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation." Cell reports.. 2017 Aug 1; 20(5):1123-1135.

3/21/2017
MacLean DM, Jayaraman V. "Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive." Proceedings of the National Academy of Sciences of the United States of America.. 2017 Mar 21; 114(12):E2504-E2513. Epub 2017 Mar 06.

2/3/2017
Vitrac H, MacLean DM, Karlstaedt A, Taegtmeyer H, Jayaraman V, Bogdanov M, Dowhan W. "Dynamic Lipid-dependent Modulation of Protein Topology by Post-translational Phosphorylation." The Journal of biological chemistry.. 2017 Feb 3; 292(5):1613-1624. Epub 2016 Dec 14.

10/4/2016
Shaikh SA, Dolino DM, Lee G, Chatterjee S, MacLean DM, Flatebo C, Landes CF, Jayaraman V. "Stargazin Modulation of AMPA Receptors." Cell reports.. 2016 Oct 4; 17(2):328-335.

5/15/2016
MacLean DM, Jayaraman V. "Acid-sensing ion channels are tuned to follow high-frequency stimuli." The Journal of physiology.. 2016 May 15; 594(10):2629-45. Epub 2016 Apr 10.

11/10/2015
Vitrac H, MacLean DM, Jayaraman V, Bogdanov M, Dowhan W. "Dynamic membrane protein topological switching upon changes in phospholipid environment." Proceedings of the National Academy of Sciences of the United States of America.. 2015 Nov 10; 112(45):13874-9. Epub 2015 Oct 28.

8/2015
Sirrieh RE, MacLean DM, Jayaraman V. "A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc." The Journal of general physiology.. 2015 Aug 0; 146(2):173-81. Epub 2015 Jul 13.

5/15/2015
Sirrieh RE, MacLean DM, Jayaraman V. "Subtype-dependent N-methyl-D-aspartate receptor amino-terminal domain conformations and modulation by spermine." The Journal of biological chemistry.. 2015 May 15; 290(20):12812-20. Epub 2015 Mar 31.

12/2014
MacLean DM, Ramaswamy SS, Du M, Howe JR, Jayaraman V. "Stargazin promotes closure of the AMPA receptor ligand-binding domain." The Journal of general physiology.. 2014 Dec 0; 144(6):503-12.

7/16/2014
Lee G, MacLean DM, Ulrich H, Zhao X, Aronowski J, Jayaraman V. "RNA based antagonist of NMDA receptors." ACS chemical neuroscience.. 2014 Jul 16; 5(7):559-67. Epub 2014 Apr 16.

12/13/2013
Ramaswamy SS, MacLean DM, Gorfe AA, Jayaraman V. "Proton-mediated conformational changes in an acid-sensing ion channel." The Journal of biological chemistry.. 2013 Dec 13; 288(50):35896-903. Epub 2013 Nov 06.

8/2/2013
Sirrieh RE, MacLean DM, Jayaraman V. "Amino-terminal domain tetramer organization and structural effects of zinc binding in the N-methyl-D-aspartate (NMDA) receptor." The Journal of biological chemistry.. 2013 Aug 2; 288(31):22555-64. Epub 2013 Jun 21.

4/1/2013
MacLean DM. "CrossTalk opposing view: TARPs modulate AMPA receptor conformations before the gating transitions." The Journal of physiology.. 2013 Apr 1; 591(7):1585-6; discussion 1587.

12/21/2012
Ramaswamy S, Cooper D, Poddar N, MacLean DM, Rambhadran A, Taylor JN, Uhm H, Landes CF, Jayaraman V. "Role of conformational dynamics in ?-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor partial agonism." The Journal of biological chemistry.. 2012 Dec 21; 287(52):43557-64. Epub 2012 Oct 31.

11/15/2011
Maclean DM, Bowie D. "Transmembrane AMPA receptor regulatory protein regulation of competitive antagonism: a problem of interpretation." The Journal of physiology.. 2011 Nov 15; 589(Pt 22):5383-90. Epub 2011 Oct 03.

2/9/2011
Maclean DM, Wong AY, Fay AM, Bowie D. "Cations but not anions regulate the responsiveness of kainate receptors." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2011 Feb 9; 31(6):2136-44.

5/27/2009
MacLean DM. "The delta2 glutamate-like receptor undergoes similar conformational changes as other ionotropic glutamate receptors." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2009 May 27; 29(21):6767-8.

6/20/2007
Wong AY, MacLean DM, Bowie D. "Na+/Cl- dipole couples agonist binding to kainate receptor activation." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2007 Jun 20; 27(25):6800-9.

9/19/2006
Kuang D, Yao Y, Maclean D, Wang M, Hampson DR, Chang BS. "Ancestral reconstruction of the ligand-binding pocket of Family C G protein-coupled receptors." Proceedings of the National Academy of Sciences of the United States of America.. 2006 Sep 19; 103(38):14050-5. Epub 2006 Sep 11.

Books & Chapters

2015
Chapter Title: Constructing a rapid solution exchange system
Book Title: Ionotropic Glutamate Receptor Technologies
Author List: MacLean, DM
Edited By: Dr. Gabriela Popescu
Published By: Springer2015