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Lauren M. Hablitz, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-0550

Fax: (585) 276-2298

Research Labs

Faculty Appointments

Biography

Dr. Hablitz is a chronobiologist focused on understanding how the body interacts with the environment over the course of a day. Some projects include how sleep affects brain function, how feeding might be used to improve stroke outcomes, and how circadian rhythms, present in every cell and process within the body, synchronize to protect against disease.

Professional Background

Dr. Hablitz earned a B.S. in Biology from The Pennsylvania State University in 2010. In 2015, Dr. Hablitz earned a Ph.D. in Cell, Molecular, and Developmental Biology from the University of Alabama Birmingham from the lab of Dr. Karen Gamble investigating conserved molecular mechanisms of nonphotic entrainment. After completing a postdoctoral research position at Oregon Health & Science University with Dr. Charles Allen, understanding the role of astrocytes in modulating cannabinoid signaling in the suprachiasmatic nucleus, Dr. Hablitz joined the Center for Translational Neuromedicine at the University of Rochester in 2017. Together with Dr. Maiken Nedergaard, Dr. Hablitz defined the endogenous, circadian rhythm of the glymphatic system and discovered a new rhythm in CSF distribution between the brain and the body.

Research

Dr. Hablitz’s research focuses on basic biological mechanisms of circadian synchrony and entrainment in health and disease. Most recently, Dr. Hablitz has been using circadian rhythms and sleep to improve glymphatic, neuronal, and cerebrovascular function in pre-clinical models of chronic neuropathic pain and stroke.

Credentials

Education

2010
BS | Pennsylvania State University
Biology

2015
PhD | University of Alabama at Birmingham
Cell and Molecular Biology

Awards


2021 Outstanding Early Investigator Award
Sponsor: Sleep Research Society


2020 Merit Award
Sponsor: Society for Research on Biological Rhythms


2016 Tartar Trust Foundation Fellowship
Sponsor: Oregon Health and Science University


2014 Trainee Award
Sponsor: Society for Research on Biological Rhythms

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Publications

Journal Articles

8/25/2022
Giannetto MJ, Hablitz LM. "Reading to the end(foot): translational readthrough of AQP4 increases amyloid-? clearance." Brain : a journal of neurology.. 2022 Aug 25; Epub 2022 Aug 25.

2022
Plá, V.; Bork, P.; Harnpramukkul, A.; Olveda, G.; Ladrón-de-Guevara, A.; Giannetto, M.; Hussain, R.; Wang, W.; Kelley, D.; Hablitz, L.; and Nedergaard, M. "A novel real-time in vivo clearance assay for quantification of glymphatic efflux". Cell Reports. 2022; .

10/25/2021
Hablitz LM, Nedergaard M. "The glymphatic system." Current biology : CB.. 2021 Oct 25; 31(20):R1371-R1375.

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