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Lauren M. Hablitz, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-0550

Fax: (585) 276-2298

Faculty Appointments

Biography

Dr. Hablitz is a chronobiologist focused on understanding how the body interacts with the environment over the course of a day. Some projects include how sleep affects brain function, how feeding might be used to improve stroke outcomes, and how circadian rhythms, present in every cell and process within the body, synchronize to protect against disease.

Professional Background

Dr. Hablitz earned a B.S. in Biology from The Pennsylvania State University in 2010. In 2015, Dr. Hablitz earned a Ph.D. in Cell, Molecular, and Developmental Biology from the University of Alabama Birmingham from the lab of Dr. Karen Gamble investigating conserved molecular mechanisms of nonphotic entrainment. After completing a postdoctoral research position at Oregon Health & Science University with Dr. Charles Allen, understanding the role of astrocytes in modulating cannabinoid signaling in the suprachiasmatic nucleus, Dr. Hablitz joined the Center for Translational Neuromedicine at the University of Rochester in 2017. Together with Dr. Maiken Nedergaard, Dr. Hablitz defined the endogenous, circadian rhythm of the glymphatic system and discovered a new rhythm in CSF distribution between the brain and the body.

Research

Dr. Hablitz’s research focuses on basic biological mechanisms of circadian synchrony and entrainment in health and disease. Most recently, Dr. Hablitz has been using circadian rhythms and sleep to improve glymphatic, neuronal, and cerebrovascular function in pre-clinical models of chronic neuropathic pain and stroke.

Credentials

Education

2010
BS | Pennsylvania State University
Biology

2015
PhD | University of Alabama at Birmingham
Cell and Molecular Biology

Awards


2021 Outstanding Early Investigator Award
Sponsor: Sleep Research Society


2020 Merit Award
Sponsor: Society for Research on Biological Rhythms


2016 Tartar Trust Foundation Fellowship
Sponsor: Oregon Health and Science University


2014 Trainee Award
Sponsor: Society for Research on Biological Rhythms

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Publications

Journal Articles

9/15/2021
Hablitz LM, Nedergaard M. "The Glymphatic System: A Novel Component of Fundamental Neurobiology." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2021 Sep 15; 41(37):7698-7711.

12/1/2020
Goldman N, Hablitz LM, Mori Y, Nedergaard M. "The Glymphatic System and Pain." . 2020 Dec 1; 32(6):373-376. Epub 2020 Dec 16.

9/30/2020
Giannetto M, Xia M, Stæger FF, Metcalfe T, Vinitsky HS, Dang JAML, Xavier ALR, Kress BT, Nedergaard M, Hablitz LM. "Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice." Scientific reports.. 2020 Sep 30; 10(1):16073. Epub 2020 Sep 30.

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