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Md Nasir Uddin, Ph.D.

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Faculty Appointments



Dr. Uddin is an Assistant Professor in the Department of Neurology and Department of Biomedical Engineering at the University of Rochester, New York. He received his B.Sc. Honours and M.Sc. in Physics and Ph.D. in Biomedical Engineering.

His research focuses on the development and application of MRI techniques to understand the structure and function in the human brain of both healthy and diseased states (e.g., Multiple Sclerosis, HIV, Cerebral Small Vessel Disease, Stroke, Parkinson's Disease, and Hypertension). Specifically, some of his interests and expertise include 1) developing MRI methods for neuroinflammation/neuronal injury and image processing pipelines; 2) investigating neuroinflammation/neurodegeneration via diffusion MRI methods such as free water imaging (FWI), neurite orientation dispersion and density imaging (NODDI), and b-tensor encoding, T2 based myelin water imaging (MWI), and multifrequency MR Elastography; 3) investigating iron sensitive measures to find potential biomarkers using quantitative susceptibility mapping (QSM) and relaxometry mappings (T2, T2*, T2’); 4) investigating vascular dysfunction via perfusion MRI and resting-state fMRI based cerebrovascular reactivity, as well as vascular remodeling using time of flight MR Angiography; and 5) investigating the relationship between structural and functional MRI measures, blood markers and cognitive performance in both healthy, aging and clinical populations.

Key Words: MRI, Brain, Neuroimaging, Iron, Myelin, Neuroinflammation, diffusion MRI, Free Water, Machine Learning, Multiple Sclerosis, HIV, CSVD.



PhD | University of Alberta
Biomedical Engineering


Magna Cum Laude
Sponsor: ISMRM

Student Scholarship
Sponsor: MS Society of Canada

SGS Merit Award
Sponsor: Memorial University

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Journal Articles

Patel R, Marrie RA, Bernstein CN, Bolton JM, Graff LA, Marriott JJ, Figley CR, Kornelsen J, Mazerolle EL, Uddin MN, Fisk JD, . "Vascular comorbidity is associated with decreased cognitive functioning in inflammatory bowel disease." Scientific reports.. 2023 Mar 15; 13(1):4317. Epub 2023 Mar 15.

Murray KD, Tivarus ME, Schifitto G, Uddin MN, Zhong J. "Brain iron imaging markers in the presence of white matter hyperintensities." Magnetic resonance imaging.. 2023 Jan 19; Epub 2023 Jan 19.

Patel, R; Marrie, RA; Bernstein, CN; Bolton, JM; Graff, LA; Marriott, JJ; Figley, CR; Kornelsen, J; Mazerolle, EL; Uddin, MN; Fisk, JD. "Vascular comorbidity is associated with decreased cognitive functioning in inflammatory bowel disease" . 2022; .