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Cesare Orlandi, Ph.D.


Showing all 32 journal articles & 1 books available

Journal Articles

Fu W, Franchini L, Orlandi C. "Comprehensive Spatial Profile of the Orphan G Protein Coupled Receptor GPRC5B Expression in Mouse Brain." Frontiers in neuroscience.. 2022 16:891544. Epub 2022 Jun 23.

Watkins LR, Orlandi C. "In vitro profiling of orphan G protein coupled receptor (GPCR) constitutive activity." British journal of pharmacology.. 2021 Mar 30; Epub 2021 Mar 30.

Cao Y, Wang Y, Dunn HA, Orlandi C, Shultz N, Kamasawa N, Fitzpatrick D, Li W, Zeitz C, Hauswirth W, Martemyanov KA. "Interplay between cell-adhesion molecules governs synaptic wiring of cone photoreceptors." Proceedings of the National Academy of Sciences of the United States of America.. 2020 Sep 2; Epub 2020 Sep 02.

Watkins LR, Orlandi C. "Orphan G Protein Coupled Receptors in Affective Disorders." Genes.. 2020 Jun 24; 11(6)Epub 2020 Jun 24.

Dunn HA, Orlandi C, Martemyanov KA. "Beyond the Ligand: Extracellular and Transcellular G Protein-Coupled Receptor Complexes in Physiology and Pharmacology." Pharmacological reviews.. 2019 Oct; 71(4):503-519.

Sutton LP, Muntean BS, Ostrovskaya O, Zucca S, Dao M, Orlandi C, Song C, Xie K, Martemyanov KA. "NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control." PLoS biology.. 2019 Oct; 17(10):e3000477. Epub 2019 Oct 10.

Wang D, Stoveken HM, Zucca S, Dao M, Orlandi C, Song C, Masuho I, Johnston C, Opperman KJ, Giles AC, Gill MS, Lundquist EA, Grill B, Martemyanov KA. "Genetic behavioral screen identifies an orphan anti-opioid system." Science.. 2019 Sep 20; 365(6459):1267-1273. Epub 2019 Aug 15.

Dunn HA, Zucca S, Dao M, Orlandi C, Martemyanov KA. "ELFN2 is a postsynaptic cell adhesion molecule with essential roles in controlling group III mGluRs in the brain and neuropsychiatric behavior." Molecular psychiatry.. 2019 Sep 4; Epub 2019 Sep 04.

Song C, Orlandi C, Sutton LP, Martemyanov KA. "The signaling proteins GPR158 and RGS7 modulate excitability of L2/3 pyramidal neurons and control A-type potassium channel in the prelimbic cortex." The Journal of biological chemistry.. 2019 Aug 30; 294(35):13145-13157. Epub 2019 Jul 16.

Orlandi C, Sutton LP, Muntean BS, Song C, Martemyanov KA. "Homeostatic cAMP regulation by the RGS7 complex controls depression-related behaviors." Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.. 2019 Feb; 44(3):642-653. Epub 2018 Oct 11.

Ostrovskaya OI, Orlandi C, Fajardo-Serrano A, Young SM, Lujan R, Martemyanov KA. "Inhibitory Signaling to Ion Channels in Hippocampal Neurons Is Differentially Regulated by Alternative Macromolecular Complexes of RGS7." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2018 Nov 14; 38(46):10002-10015. Epub 2018 Oct 12.

Condomitti G, Wierda KD, Schroeder A, Rubio SE, Vennekens KM, Orlandi C, Martemyanov KA, Gounko NV, Savas JN, de Wit J. "An Input-Specific Orphan Receptor GPR158-HSPG Interaction Organizes Hippocampal Mossy Fiber-CA3 Synapses." Neuron.. 2018 Oct 10; 100(1):201-215.e9. Epub 2018 Oct 02.

Orlandi C, Omori Y, Wang Y, Cao Y, Ueno A, Roux MJ, Condomitti G, de Wit J, Kanagawa M, Furukawa T, Martemyanov KA. "Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors." Cell reports.. 2018 Oct 2; 25(1):130-145.e5.

Dunn HA, Patil DN, Cao Y, Orlandi C, Martemyanov KA. "Synaptic adhesion protein ELFN1 is a selective allosteric modulator of group III metabotropic glutamate receptors ." Proceedings of the National Academy of Sciences of the United States of America.. 2018 May 8; 115(19):5022-5027. Epub 2018 Apr 23.

Sarria I, Cao Y, Wang Y, Ingram NT, Orlandi C, Kamasawa N, Kolesnikov AV, Pahlberg J, Kefalov VJ, Sampath AP, Martemyanov KA. "LRIT1 Modulates Adaptive Changes in Synaptic Communication of Cone Photoreceptors." Cell reports.. 2018 Mar 27; 22(13):3562-3573.

Sutton LP, Orlandi C, Song C, Oh WC, Muntean BS, Xie K, Filippini A, Xie X, Satterfield R, Yaeger JDW, Renner KJ, Young SM, Xu B, Kwon H, Martemyanov KA. "Orphan receptor GPR158 controls stress-induced depression." eLife.. 2018 Feb 8; 7Epub 2018 Feb 08.

Xie K, Colgan LA, Dao MT, Muntean BS, Sutton LP, Orlandi C, Boye SL, Boye SE, Shih CC, Li Y, Xu B, Smith RG, Yasuda R, Martemyanov KA. "NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum." Current biology : CB.. 2016 Nov 21; 26(22):2992-3003. Epub 2016 Oct 20.

Sutton LP, Ostrovskaya O, Dao M, Xie K, Orlandi C, Smith R, Wee S, Martemyanov KA. "Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum." Biological psychiatry.. 2016 Aug 1; 80(3):235-45. Epub 2015 Aug 14.

Tayou J, Wang Q, Jang GF, Pronin AN, Orlandi C, Martemyanov KA, Crabb JW, Slepak VZ. "Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by G?o and R7-binding Protein." The Journal of biological chemistry.. 2016 Apr 22; 291(17):9133-47. Epub 2016 Feb 19.

Sarria I, Orlandi C, McCall MA, Gregg RG, Martemyanov KA. "Intermolecular Interaction between Anchoring Subunits Specify Subcellular Targeting and Function of RGS Proteins in Retina ON-Bipolar Neurons." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2016 Mar 9; 36(10):2915-25.

Xu Y, Orlandi C, Cao Y, Yang S, Choi CI, Pagadala V, Birnbaumer L, Martemyanov KA, Vardi N. "The TRPM1 channel in ON-bipolar cells is gated by both the ? and the ?? subunits of the G-protein Go." Scientific reports.. 2016 Feb 17; 6:20940. Epub 2016 Feb 17.

Aguado C, Orlandi C, Fajardo-Serrano A, Gil-Minguez M, Martemyanov KA, Luján R. "Cellular and Subcellular Localization of the RGS7/G?5/R7BP Complex in the Cerebellar Cortex." Frontiers in neuroanatomy.. 2016 10:114. Epub 2016 Nov 30.

Cao Y, Sarria I, Fehlhaber KE, Kamasawa N, Orlandi C, James KN, Hazen JL, Gardner MR, Farzan M, Lee A, Baker S, Baldwin K, Sampath AP, Martemyanov KA. "Mechanism for Selective Synaptic Wiring of Rod Photoreceptors into the Retinal Circuitry and Its Role in Vision." Neuron.. 2015 Sep 23; 87(6):1248-1260.

Orlandi C, Xie K, Masuho I, Fajardo-Serrano A, Lujan R, Martemyanov KA. "Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain." The Journal of biological chemistry.. 2015 May 29; 290(22):13622-39. Epub 2015 Mar 19.

Orlandi C, Cao Y, Martemyanov KA. "Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons." Investigative ophthalmology & visual science.. 2013 Oct 29; 54(10):7153-61. Epub 2013 Oct 29.

La Via L, Bonini D, Russo I, Orlandi C, Barlati S, Barbon A. "Modulation of dendritic AMPA receptor mRNA trafficking by RNA splicing and editing." Nucleic acids research.. 2013 Jan 7; 41(1):617-31. Epub 2012 Nov 19.

Orlandi C, Posokhova E, Masuho I, Ray TA, Hasan N, Gregg RG, Martemyanov KA. "GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes." The Journal of cell biology.. 2012 Jun 11; 197(6):711-9.

Orlandi C, Barbon A, Barlati S. "Activity regulation of adenosine deaminases acting on RNA (ADARs)." Molecular neurobiology.. 2012 Feb; 45(1):61-75. Epub 2011 Nov 20.

Barbon A, Caracciolo L, Orlandi C, Musazzi L, Mallei A, La Via L, Bonini D, Mora C, Tardito D, Gennarelli M, Racagni G, Popoli M, Barlati S. "Chronic antidepressant treatments induce a time-dependent up-regulation of AMPA receptor subunit protein levels." Neurochemistry international.. 2011 Nov; 59(6):896-905. Epub 2011 Aug 03.

Barbon A, Orlandi C, La Via L, Caracciolo L, Tardito D, Musazzi L, Mallei A, Gennarelli M, Racagni G, Popoli M, Barlati S. "Antidepressant treatments change 5-HT2C receptor mRNA expression in rat prefrontal/frontal cortex and hippocampus." Neuropsychobiology. 2011 63(3):160-8. Epub 2011 Jan 13.

Orlandi C, La Via L, Bonini D, Mora C, Russo I, Barbon A, Barlati S. "AMPA receptor regulation at the mRNA and protein level in rat primary cortical cultures." PloS one.. 2011 6(9):e25350. Epub 2011 Sep 22.

Barbon A, Gervasoni A, LaVia L, Orlandi C, Jaskolski F, Perrais D, Barlati S. "Human GluR6c, a functional splicing variants of GluR6, is mainly expressed in non-nervous cells." Neuroscience letters.. 2008 Mar 21; 434(1):77-82. Epub 2008 Feb 02.

Books & Chapters

Chapter Title: Probing the orphan receptors: Tools and directions
Book Title: Progress in Molecular Biology and Translational Science
Author List: Luca Franchini Cesare Orlandi
Published By: Elsevier2022