Brian Marples, Ph.D.

Kerns SL, Hall WA, Marples B, West CML

Seminars in radiation oncology.. 2023 July 33 (3):307-316. Epub 1900 01 01.

Wilson GD, Rogers CL, Mehta MP, Marples B, Michael DB, Welsh JS, Martinez AA, Fontanesi J

Radiation research.. 2023 May 1199 (5):506-516. Epub 1900 01 01.

Verhaegen F, Butterworth KT, Chalmers AJ, Coppes RP, de Ruysscher D, Dobiasch S, Fenwick JD, Granton PV, Heijmans SHJ, Hill MA, Koumenis C, Lauber K, Marples B, Parodi K, Persoon LCGG, Staut N, Subiel A, Vaes RDW, van Hoof S, Verginadis IL, Wilkens JJ, Williams KJ, Wilson GD, Dubois LJ

Physics in medicine and biology.. 2023 March 3168 (6)Epub 03/31/2023.

Kerns SL, Williams JP, Marples B

International journal of radiation biology.. 2023 February 28 :1-13. Epub 02/28/2023.

Influence of the irradiated pulmonary microenvironment on macrophage and T cell dynamics

Groves AM; Misra R; Clair G; Hernady E; Olson H; Orton D; Finkelstein J; Marples B; Johnston CJ.

Radiother Oncol. 2023; 183: 109543.

Williams JP, Anscher MS, Vazquez M, Kronenberg A, Willey JS, Lawrence T, Woloschak GE, Marples B, Wong R, Howell RW

Journal of applied clinical medical physics. 2022 December 23 Suppl 1 :e13743. Epub 1900 01 01.

Newhauser WD, Williams JP, Noska MA, Borrás C, Holahan EV, Dewji SA, Johnson TE, Hiatt JW, Poston JW, Hertel N, Gress DA, Mills MD, Jordan DW, Sutlief SG, Martin MC, Jackson E, Bluth EI, Frush DP, Oates ME, LaBerge J, Pan HY, Rosenthal SA, Townsend LW, Brady L, Lindegard J, Hall HL, McAndrew-Benavides E, Abelquist E, Anscher MS, Vazquez M, Kronenberg A, Willey JS, Lawrence T, Woloschak GE, Marples B, Wong R, Story M, Howell RW, Hei TK, Tolmachev SY, Auxier JD, Rucker TL, Nilsson M, Sudowe R, Powell BA, Jensen MP

Journal of applied clinical medical physics. 2022 December 23 Suppl 1 :e13848. Epub 1900 01 01.

Groves AM, Paris N, Hernady E, Johnston CJ, Aljitawi O, Lee YF, Kerns SL, Marples B

International journal of radiation oncology, biology, physics.. 2022 November 15 Epub 11/15/2022.

Jacobson GM, Bajaj GK, Buatti JM, Dawson L, Deville C, Eichler TJ, Erickson B, Ford E, Gibbs IC, Mantz C, Marples B, Michalski JM, Sandler H, Smith B, Vapiwala N, Yashar C

International journal of radiation oncology, biology, physics.. 2022 November 1114 (3):390-392. Epub 08/10/2022.

Mallela SK, Ge M, Molina J, Santos JV, Kim JJ, Mitrofanova A, Al-Ali H, Marples B, Merscher S, Fornoni A

Genes & diseases.. 2022 November 9 (6):1397-1400. Epub 02/03/2022.

Bodgi L, Francis M, Azzam P, Ahmad A, Youssef T, Bodgi L, Abou Daher A, Azzam P, Eid AA, Youssef T, Fornoni A, Abou Daher A, Pollack A, Eid AA, Marples B, Fornoni A, Zeidan YH, Pollack A, Marples B, Zeidan YH

FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2022 October 36 (10):e22545. Epub 1900 01 01.

Use of angiotensin converting enzyme inhibitors is associated with reduced risk of late bladder toxicity following radiotherapy for prostate cancer

Kerns SL; Amidon Morlang A; Lee SM; Peterson DR; Marples B; Zhang H; Bylund K; Rosenzweig D; Hall W; De Ruyck K; Rosenstein BS; Stock RG; Gómez-Caamaño A; Vega A; Sosa-Fajardo P; Taboada-Valladares B; Aguado-Barrera ME; Parker C; Veldeman L; Fonteyne V; Bultijnck R; Talbot CJ; Symonds RP; Johnson K; Rattay T; Webb A; Lambrecht M; de Ruysscher D; Vanneste B; Choudhury A; Elliott RM; Sperk E; Herskind C; Veldwijk MR; Rancati T; Avuzzi B; Valdagni R; Azria D; Farcy Jacquet MP; Chang-Claude J; et al.

Radiother Oncol. 2022; 168: 75-82.

Pulsed radiation therapy for the treatment of newly diagnosed glioblastoma

Almahariq MF; Quinn TJ; Arden JD; Roskos PT; Wilson GD; Marples B; Grills IS; Chen PY; Krauss DJ; Chinnaiyan P; Dilworth JT.

Neuro Oncol. 2021; 23(3): 447-456.

Noninvasive assessment of radiation-induced renal injury in mice

Ahmad A; Shi J; Ansari S; Afaghani J; Molina J; Pollack A; Merscher S; Zeidan YH; Fornoni A; Marples B.

Int J Radiat Biol. 2021; 97(5): 664-674.

Reflections of the Senior Editors for Biology

Brown JM; Freeman ML; Marples B; Boerma M.

Int J Radiat Oncol Biol Phys. 2021; 111(5): 1118-1119.

Crosstalk between SMPDL3b and NADPH oxidases mediates radiation-induced damage of renal podocytes

Azzam P; Francis M; Youssef T; Mroueh M; Daher AA; Eid AA; Fornoni A; Marples B; Zeidan YH.

Front Med (Lausanne). 2021; 8: 732528.

In vivo imaging of the microglial landscape after whole brain radiation therapy

Whitelaw BS; Tanny S; Johnston CJ; Majewska AK; O'Banion MK; Marples B.

Int J Radiat Oncol Biol Phys. 2021; 111(4): 1066-1071.

Prasanna PG, Woloschak GE, DiCarlo AL, Buchsbaum JC, Schaue D, Chakravarti A, Cucinotta FA, Formenti SC, Guha C, Hu DJ, Khan MK, Kirsch DG, Krishnan S, Leitner WW, Marples B, McBride W, Mehta MP, Rafii S, Sharon E, Sullivan JM, Weichselbaum RR, Ahmed MM, Vikram B, Coleman CN, Held KD

Radiation research.. 2020 November 10194 (5):452-464. Epub 1900 01 01.

Udayakumar TS, Betancourt DM, Ahmad A, Tao W, Totiger TM, Patel M, Marples B, Barber G, Pollack A

Molecular cancer research : MCR.. 2020 August 18 (8):1232-1243. Epub 05/04/2020.

Dacomitinib and gedatolisib in combination with fractionated radiation in head and neck cancer

Wilson GD; Wilson TG; Hanna A; Dabjan M; Buelow K; Torma J; Marples B; Galoforo S.

Clin Transl Radiat Oncol. 2020; 26(15-23).

Oncology Scan: Radiation Biology and Genomic Predictors of Response

Marples B; Kerns S.

Int J Radiat Oncol Biol Phys. 2020; 107(3): 393-397.

Modulation of radiation-induced damage of human glomerular endothelial cells by SMPDL3B

Abou Daher A; Francis M; Azzam P; Ahmad A; Eid AA; Fornoni A; Marples B; Zeidan YH.

FASEB J. 2020; 34(6): 7915-7926.

Phase I Trial of MRI-Guided Prostate Cancer Lattice Extreme Ablative Dose (LEAD) Boost Radiation Therapy

Pollack A; Chinea FM; Bossart E; Kwon D; Abramowitz MC; Lynne C; Jorda M; Marples B; Patel VN; Wu X; Reis I; Studenski MT; Casillas J; Stoyanova R.

Int J Radiat Oncol Biol Phys. 2020; 107(2): 305-315.

Predicting Outcome using Genomic-Based Liquid Biomarkers

Marples B; Wilson GD.

Int J Radiat Oncol Biol Phys. 2020; 106(1): 1-4.

The Need for Accurate Reporting of Dosimetric Conditions in Radiobiology Studies

Marples B.

Int J Radiat Oncol Biol Phys. 2020; 106(2): 253-254.

Targeting Glioblastoma Stem Cells with 2-Deoxy-D-Glucose (2-DG) Potentiates Radiation-Induced Unfolded Protein Response (UPR)

Shah SS; Rodriguez GA; Musick A; Walters WM; de Cordoba N; Barbarite E; Marlow MM; Marples B; Prince JS; Komotar RJ; Vanni S; Graham RM.

Cancers (Basel). 2019; 11(2): 159.

Nanotechnology-mediated crossing of two impermeable membranes to modulate the stars of the neurovascular unit for neuroprotection

Surnar B; Basu U; Banik B; Ahmad A; Marples B; Kolishetti N; Dhar S.

Proc Natl Acad Sci U S A. 2018; 115(52): E12333-E12342.

Reduction of Cisplatin-Induced Ototoxicity without Compromising Its Antitumor Activity

Surnar B; Kolishetti N; Basu U; Ahmad A; Goka E; Marples B; Kolb D; Lippman ME; Dhar S.

Biochemistry. 2018; 57(46): 6500-6513.

A designer bow-tie combination therapeutic platform: An approach to resistant cancer treatment by simultaneous delivery of cytotoxic and anti-inflammatory agents and radiation

Pathak RK; Basu U; Ahmad A; Sarkar S; Kumar A; Surnar B; Ansari S; Wilczek K; Ivan ME; Marples B; Kolishetti N; Dhar S.

Biomaterials. 2018; 187: 117-129.

Dual blockade of PI3K and MEK in combination with radiation in head and neck cancer

Blas K; Wilson TG; Tonlaar N; Galoforo S; Hana A; Marples B; Wilson GD.

Clin Transl Radiat Oncol. 2018; 11: 1-10.

The Future of Radiobiology

Kirsch DG; Diehn M; Kesarwala AH; Maity A; Morgan MA; Schwarz JK; Bristow R; Demaria S; Eke I; Griffin RJ; Haas-Kogan D; Higgins GS; Kimmelman AC; Kimple RJ; Lombaert IM; Ma L; Marples B; Pajonk F; Park CC; Schaue D; Tran PT; Willers H; Wouters BG; Bernhard EJ.

J Natl Cancer Inst. 2018; 110(4): 329-340.

Radiation Biology and Circulating Tumor Cells

Marples B; Welford SM.

Int J Radiat Oncol Biol Phys. 2018; 100(4): 813-815.

Translational Aspects of Sphingolipid Metabolism in Renal Disorders

Abou Daher A; El Jalkh T; Eid AA; Fornoni A; Marples B; Zeidan YH.

Int J Mol Sci. 2017; 18(12): 2528.

Automatic Detection and Quantitative DCE-MRI Scoring of Prostate Cancer Aggressiveness

Parra NA; Pollack A; Chinea FM; Abramowitz MC; Marples B; Munera F; Castillo R; Kryvenko ON; Punnen S; Stoyanova R.

Front Oncol. 2017; 7: 259.

Antitumor activity of the dual PI3K/MTOR inhibitor, PF-04691502, in combination with radiation in head and neck cancer

Tonlaar N; Galoforo S; Thibodeau BJ; Ahmed S; Wilson TG; Yumpo Cardenas P; Marples B; Wilson GD.

Radiother Oncol. 2017; 124(3): 504-512.

Molecular Profiling in the Practice of Radiation Oncology

Marples B; Pollack A.

Oncology (Williston Park). 2017; 31(7): 571-572.

Radiobiology and the Renewed Potential for Nanoparticles

Marples B; Dhar S.

Int J Radiat Oncol Biol Phys. 2017; 98(3): 489-491.

Sphingomyelinase-like phosphodiesterase 3b mediates radiation-induced damage of renal podocytes

Ahmad A; Mitrofanova A; Bielawski J; Yang Y; Marples B; Fornoni A; Zeidan YH.

FASEB J. 2017; 31(2): 771-780.

Modeling of chronic radiation-induced cystitis in mice

Zwaans BM; Krueger S; Bartolone SN; Chancellor MB; Marples B; Lamb LE.

Adv Radiat Oncol. 2016; 1(4): 333-343.

A survey of changing trends in modelling radiation lung injury in mice: bringing out the good, the bad, and the uncertain

Dabjan MB; Buck CM; Jackson IL; Vujaskovic Z; Marples B; Down JD.

Lab Invest. 2016; 96(9): 936-949.

Effect of Irradiation on Tumor Microenvironment and Bone Marrow Cell Migration in a Preclinical Tumor Model

Kane JL; Krueger SA; Hanna A; Raffel TR; Wilson GD; Madlambayan GJ; Marples B.

Int J Radiat Oncol Biol Phys. 2016; 96(1): 170-178.

Pulsed Radiation Therapy With Concurrent Cisplatin Results in Superior Tumor Growth Delay in a Head and Neck Squamous Cell Carcinoma Murine Model

Meyer K; Krueger SA; Kane JL; Wilson TG; Hanna A; Dabjan M; Hege KM; Wilson GD; Grills I; Marples B.

Int J Radiat Oncol Biol Phys. 2016; 96(1): 161-169.

A New Use for an Old Treatment: Radiation Therapy and Alzheimer's Disease

Wilson GD; Marples B.

Radiat Res. 2016; 185(5): 443-448.

Cranial irradiation significantly reduces beta amyloid plaques in the brain and improves cognition in a murine model of Alzheimer's Disease (AD)

Marples B; McGee M; Callan S; Bowen SE; Thibodeau BJ; Michael DB; Wilson GD; Maddens ME; Fontanesi J; Martinez AA.

Radiother Oncol. 2016; 118(3): 579-580.

Cancer Stem Cell Signaling during Repopulation in Head and Neck Cancer

Wilson GD; Thibodeau BJ; Fortier LE; Pruetz BL; Galoforo S; Marples B; Baschnagel AM; Akervall J; Huang J.

Stem Cells Int. 2016; 2016(1894782).

Cranial irradiation significantly reduces beta amyloid plaques in the brain and improves cognition in a murine model of Alzheimer's Disease (AD)

Marples B; McGee M; Callan S; Bowen SE; Thibodeau BJ; Michael DB; Wilson GD; Maddens ME; Fontanesi J; Martinez AA.

Radiother Oncol. 2016; 118(1): 43-51.

Fractionated radiation exposure amplifies the radioresistant nature of prostate cancer cells

McDermott N; Meunier A; Mooney B; Nortey G; Hernandez C; Hurley S; Lynam-Lennon N; Barsoom SH; Bowman KJ; Marples B; Jones GD; Marignol L.

Sci Rep. 2016; 6: 34796.

Novel CARM1-Interacting Protein, DZIP3, Is a Transcriptional Coactivator of Estrogen Receptor-?

Purcell DJ; Chauhan S; Jimenez-Stinson D; Elliott KR; Tsewang TD; Lee YH; Marples B; Lee DY.

Mol Endocrinol. 2015; 29(12): 1708-1719.

The Effects of Pulsed Radiation Therapy on Tumor Oxygenation in 2 Murine Models of Head and Neck Squamous Cell Carcinoma

Wobb J; Krueger SA; Kane JL; Galoforo S; Grills IS; Wilson GD; Marples B.

Int J Radiat Oncol Biol Phys. 2015; 92(4): 820-828.

Intravesical Liposomal Tacrolimus Protects against Radiation Cystitis Induced by 3-Beam Targeted Bladder Radiation

Rajaganapathy BR; Janicki JJ; Levanovich P; Tyagi P; Hafron J; Chancellor MB; Krueger S; Marples B.

J Urol. 2015; 194(2): 578-584.

Association of ATM activation and DNA repair with induced radioresistance after low-dose irradiation

Enns L; Rasouli-Nia A; Hendzel M; Marples B; Weinfeld M.

Radiat Prot Dosimetry. 2015; 166(1-4): 131-136.

Glucose metabolism gene expression patterns and tumor uptake of ¹?F-fluorodeoxyglucose after radiation treatment

Wilson GD; Thibodeau BJ; Fortier LE; Pruetz BL; Galoforo S; Baschnagel AM; Chunta J; Oliver Wong CY; Yan D; Marples B; Huang J.

Int J Radiat Oncol Biol Phys. 2014; 90(3): 620-627.

Gene expression changes during repopulation in a head and neck cancer xenograft

Wilson GD; Thibodeau BJ; Fortier LE; Pruetz BL; Galoforo S; Akervall J; Marples B; Huang J.

Radiother Oncol. 2014; 113(1): 139-145.

Exposure to low dose ionising radiation: Molecular and clinical consequences

Martin LM; Marples B; Lynch TH; Hollywood D; Marignol L.

Cancer Lett. 2014; 349(1): 98-106.

Preclinical models for translational research should maintain pace with modern clinical practice

Dilworth JT; Krueger SA; Wilson GD; Marples B.

Int J Radiat Oncol Biol Phys. 2014; 88(3): 540-544.

Early treatment response monitoring using 2-deoxy-2-[ 18F]fluoro-D-glucose positron emission tomography imaging during fractionated radiotherapy of head neck cancer xenografts

Huang J; Chunta JL; Amin M; Lee DY; Grills IS; Oliver Wong CY; Marples B; Yan D; Wilson GD.

Biomed Res Int. 2014; 2014: 598052.

Current status and recommendations for the future of research, teaching, and testing in the biological sciences of radiation oncology: report of the American Society for Radiation Oncology Cancer Biology/Radiation Biology Task Force, executive summary

Wallner PE; Anscher MS; Barker CA; Bassetti M; Bristow RG; Cha YI; Dicker AP; Formenti SC; Graves EE; Hahn SM; Hei TK; Kimmelman AC; Kirsch DG; Kozak KR; Lawrence TS; Marples B; McBride WH; Mikkelsen RB; Park CC; Weidhaas JB; Zietman AL; Steinberg M.

Int J Radiat Oncol Biol Phys. 2014; 88(1): 11-17.

Hematopoietic stem and progenitor cell migration after hypofractionated radiation therapy in a murine model

Kane J; Krueger SA; Dilworth JT; Torma JT; Wilson GD; Marples B; Madlambayan GJ.

Int J Radiat Oncol Biol Phys. 2013; 87(5): 1162-1170.

Determining if low dose hyper-radiosensitivity (HRS) can be exploited to provide a therapeutic advantage: a cell line study in four glioblastoma multiforme (GBM) cell lines

Schoenherr D; Krueger SA; Martin L; Marignol L; Wilson GD; Marples B.

Int J Radiat Biol. 2013; 89(12): 1009-1016.

Pulsed versus conventional radiation therapy in combination with temozolomide in a murine orthotopic model of glioblastoma multiforme

Lee DY, Chunta JL, Park SS, Huang J, Martinez AA, Grills IS, Krueger SA, Wilson GD, Marples B.

Int J Radiat Oncol Biol Phys. 2013; 86(5): 978-985.

Pulsed low-dose irradiation of orthotopic glioblastoma multiforme (GBM) in a pre-clinical model: effects on vascularization and tumor control

Dilworth JT; Krueger SA; Dabjan M; Grills IS; Torma J; Wilson GD; Marples B.

Radiother Oncol. 2013; 108(1): 149-154.

Exposure to low dose ionising radiation: molecular and clinical consequences

Martin LM; Marples B; Lynch TH; Hollywood D; Marignol L.

Cancer Lett. 2013; 338(2): 209-218.

DNA mismatch repair protein MSH2 dictates cellular survival in response to low dose radiation in endometrial carcinoma cells

Martin LM; Marples B; Davies AM; Atzberger A; Edwards C; Lynch TH; Hollywood D; Marignol L.

Cancer Lett. 2013; 335(1): 19-25.

External beam pulsed low dose radiotherapy using volumetric modulated arc therapy: planning and delivery

Tyagi N; Yang K; Sandhu R; Yan D; Park SS; Chen PY; Marples B.

Med Phys. 2013; 40(1): 011704.

Isolation and genomic characterization of stem cells in head and neck cancer

Wilson GD; Marples B; Galoforo S; Geddes TJ; Thibodeau BJ; Grénman R; Akervall J.

Head Neck. 2013; 35(11): 1573-1582.

Detailed characterization of the early response of head-neck cancer xenografts to irradiation using (18)F-FDG-PET imaging

Huang J; Chunta JL; Amin M; Lee DY; Grills IS; Wong CY; Yan D, Marples B, Martinez AA, Wilson GD.

Int J Radiat Oncol Biol Phys. 2012; 84(2): 485-491.

MicroPET/CT imaging of an orthotopic model of human glioblastoma multiforme and evaluation of pulsed low-dose irradiation

Park SS; Chunta JL; Robertson JM; Martinez AA; Oliver Wong CY; Amin M; Wilson GD; Marples B.

Int J Radiat Oncol Biol Phys. 2011; 80(3): 885-892.

TMPRSS2/ERG fusion gene expression alters chemo- and radio-responsiveness in cell culture models of androgen independent prostate cancer

Swanson TA; Krueger SA; Galoforo S; Thibodeau BJ; Martinez AA; Wilson GD; Marples B.

Prostate. 2011; 71(14): 1548-1558.

Pulmonary injury after combined exposures to low-dose low-LET radiation and fungal spores

Marples B; Downing L; Sawarynski KE; Finkelstein JN; Williams JP; Martinez AA; Wilson GD; Sims MD.

Radiat Res. 2011; 175(4): 501-509.

Sorafenib and radiation: a promising combination in colorectal cancer

Suen AW, Galoforo S, Marples B, McGonagle M, Downing L, Martinez AA, Robertson JM, Wilson GD.

Int J Radiat Oncol Biol Phys. 2010; 78(1): 213-220.

The effects of G2-phase enrichment and checkpoint abrogation on low-dose hyper-radiosensitivity

Krueger SA; Wilson GD; Piasentin E; Joiner MC; Marples B.

Int J Radiat Oncol Biol Phys. 2010; 77(5): 1509-1517.

Significant dose can be lost by extended delivery times in IMRT with x rays but not high-LET radiations

Joiner MC; Mogili N; Marples B; Burmeister J.

Med Phys. 2010; 37(6): 2457-2465.

Mitochondrial gene expression changes in normal and mitochondrial mutant cells after exposure to ionizing radiation

Kulkarni R; Marples B; Balasubramaniam M; Thomas RA; Tucker JD.

Radiat Res. 2010; 173(5): 635-644.

DNA mismatch repair and the DNA damage response to ionizing radiation: making sense of apparently conflicting data

Martin LM; Marples B; Coffey M; Lawler M; Lynch TH; Hollywood D; Marignol L.

Cancer Treat Rev. 2010; 36(7): 518-527.

Prostate-specific natural health products (dietary supplements) radiosensitize normal prostate cells

Hasan Y; Schoenherr D; Martinez AA; Wilson GD; Marples B.

Int J Radiat Oncol Biol Phys. 2010; 76(3): 896-904.

Bystander effects induced by chemicals and ionizing radiation: evaluation of changes in gene expression of downstream MAPK targets

Asur R; Balasubramaniam M; Marples B; Thomas RA; Tucker JD.

Mutagenesis. 2010; 25(3): 271-279.

Involvement of MAPK proteins in bystander effects induced by chemicals and ionizing radiation

Asur R; Balasubramaniam M; Marples B; Thomas RA; Tucker JD.

Mutat Res. 2010; 686(1-2): 15-29.

A simple quantitative method for assessing pulmonary damage after x irradiation

Downing L; Sawarynski KE; Li J; McGonagle M; Sims MD; Marples B.

Radiat Res. 2010; 173(4): 536-544.

Recognition of O6MeG lesions by MGMT and mismatch repair proficiency may be a prerequisite for low-dose radiation hypersensitivity

Martin L; Marples B; Coffey M; Lawler M; Hollywood D; Marignol L.

Radiat Res. 2009; 172(4): 405-413.

Early dose response to yttrium-90 microsphere treatment of metastatic liver cancer by a patient-specific method using single photon emission computed tomography and positron emission tomography

Campbell JM; Wong CO; Muzik O; Marples B; Joiner M; Burmeister J.

Int J Radiat Oncol Biol Phys. 2009; 74(1): 313-320.

Low-dose hyper-radiosensitivity: past, present, and future

Marples B; Collis SJ.

Int J Radiat Oncol Biol Phys. 2008; 70(5): 1310-1318.

Transition in survival from low-dose hyper-radiosensitivity to increased radioresistance is independent of activation of ATM Ser1981 activity

Krueger SA; Collis SJ; Joiner MC; Wilson GD; Marples B.

Int J Radiat Oncol Biol Phys. 2007; 69(4): 1262-1271.

Flow cytometry in radiation research: past, present and future

Wilson GD; Marples B.

Radiat Res. 2007; 168(4): 391-403.

Role of apoptosis in low-dose hyper-radiosensitivity

Krueger SA; Joiner MC; Weinfeld M; Piasentin E; Marples B.

Radiat Res. 2007; 167(3): 260-267.

Metabolic remodeling of malignant gliomas for enhanced sensitization during radiotherapy: an in vitro study

Colen CB; Seraji-Bozorgzad N; Marples B; Galloway MP; Sloan AE; Mathupala SP.

Neurosurgery. 2006; 59(6): 1313-1323.

Low-dose hyper-radiosensitivity is not caused by a failure to recognize DNA double-strand breaks

Wykes SM; Piasentin E; Joiner MC; Wilson GD; Marples B.

Radiat Res. 2006; 165(5): 516-524.

Gene therapy vectors containing CArG elements from the Egr1 gene are activated by neutron irradiation, cisplatin and doxorubicin

Greco O; Powell TM; Marples B; Joiner MC; Scott SD.

Cancer Gene Ther. 2005; 12(7): 655-662.

Radiation-induced gene therapy

Greco O; Marples B; Wilson GD; Joiner MC; Scott SD.

Radiat Res. 2005; 163(6): 707-708.

Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model

Hillman GG; Wang Y; Kucuk O; Che M; Doerge DR; Yudelev M; Joiner MC; Marples B; Forman JD; Sarkar FH.

Mol Cancer Ther. 2004; 3(10): 1271-1279.

Persistence of chromosome aberrations in mice acutely exposed to 56Fe+26 ions

Tucker JD; Marples B; Ramsey MJ; Lutze-Mann LH.

Radiat Res. 2004; 161(6): 648-655.

Organocatalysis of asymmetric epoxidation mediated by iminium salts under nonaqueous conditions

Page PC; Barros D; Buckley BR; Ardakani A; Marples BA.

J Org Chem. 2004; 69(10): 3595-3597.

PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation

Chalmers A; Johnston P; Woodcock M; Joiner M; Marples B.

Int J Radiat Oncol Biol Phys. 2004; 58(2): 410-419.

Radiation-activated antitumor vectors

Scott SD; Marples B.

Methods Mol Med. 2004; 90: 389-402.

Low-dose hyper-radiosensitivity: a consequence of ineffective cell cycle arrest of radiation-damaged G2-phase cells

Marples B; Wouters BG; Collis SJ; Chalmers AJ; Joiner MC.

Radiat Res. 2004; 161(3): 247-255.

Is low-dose hyper-radiosensitivity a measure of G2-phase cell radiosensitivity?

Marples B.

Cancer Metastasis Rev. 2004; 23(3-4): 197-207.

How to overcome (and exploit) tumor hypoxia for targeted gene therapy

Greco O; Marples B; Joiner MC; Scott SD.

J Cell Physiol. 2003; 197(3): 312-325.

Radiogenetic therapy: strategies to overcome tumor resistance

Marples B; Greco O; Joiner MC; Scott SD.

Curr Pharm Des. 2003; 9(26): 2105-2112.

Effects of cell cycle phase on low-dose hyper-radiosensitivity

Short SC; Woodcock M; Marples B; Joiner MC.

Int J Radiat Biol. 2003; 79(2): 99-105.

An association between the radiation-induced arrest of G2-phase cells and low-dose hyper-radiosensitivity: a plausible underlying mechanism?

Marples B; Wouters BG; Joiner MC.

Radiat Res. 2003; 160(1): 38-45.

Cancer gene therapy: 'delivery, delivery, delivery'

Greco O; Scott SD; Marples B; Dachs GU.

Front Biosci. 2002; 7: d1516-24.

Molecular approaches to chemo-radiotherapy

Marples B; Greco O; Joiner MC; Scott SD.

Eur J Cancer. 2002; 38(2): 231-239.

The effects of low-dose X-irradiation on the oxidative burst in stimulated macrophages

Schaue D; Marples B; Trott KR.

Int J Radiat Biol. 2002; 78(7): 567-576.

Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy

Scott SD; Joiner MC; Marples B.

Gene Ther. 2002; 9(20): 1396-1402.

Novel chimeric gene promoters responsive to hypoxia and ionizing radiation

Greco O; Marples B; Dachs GU; Williams KJ; Patterson AV; Scott SD.

Gene Ther. 2002; 9(20): 1403-1411.

Evidence for the involvement of DNA-dependent protein kinase in the phenomena of low dose hyper-radiosensitivity and increased radioresistance

Marples B; Cann NE; Mitchell CR; Johnston PJ; Joiner MC.

Int J Radiat Biol. 2002; 78(12): 1139-1147.

Low-dose hypersensitivity: current status and possible mechanisms

Joiner MC; Marples B; Lambin P; Short SC; Turesson I.

Int J Radiat Oncol Biol Phys. 2001; 49(2): 379-389.

Technical report: SYBR Green I and the improved sensitivity of the single-cell electrophoresis assay

Ward TH; Marples B.

Int J Radiat Biol. 2000; 76(1): 61-65.

Modification of survival by DNA repair modifiers: a probable explanation for the phenomenon of increased radioresistance

Marples B; Joiner MC.

Int J Radiat Biol. 2000; 76(3): 305-312.

Development of synthetic promoters for radiation-mediated gene therapy

Marples B; Scott SD; Hendry JH; Embleton MJ; Lashford LS; Margison GP.

Gene Ther. 2000; 7(6): 511-517.

A radiation-controlled molecular switch for use in gene therapy of cancer

Scott SD; Marples B; Hendry JH; Lashford LS; Embleton MJ; Hunter RD; Howell A; Margison GP.

Gene Ther. 2000; 7(13): 1121-1125.

Comment on the use of the cre/loxP recombinase system for gene therapy vectors

Scott SD; Marples B.

Gene Ther. 2000; 7(19): 1706.

Adaptive response and induced resistance

Joiner MC; Lambin P; Marples B.

C R Acad Sci III. 1999; 322(2-3): 167-175.

Fibroblast radiosensitivity measured using the comet DNA-damage assay correlates with clonogenic survival parameters

Eastham AM; Marples B; Kiltie AE; Orton CJ; West CM.

Br J Cancer. 1999; 79(9-10): 1366-1371.

DNA damage in human and mouse spermatozoa after in vitro-irradiation assessed by the comet assay

Haines G; Marples B; Daniel P; Morris I.

Adv Exp Med Biol. 1998; 444(79-91).

The ratio of initial/residual DNA damage predicts intrinsic radiosensitivity in seven cervix carcinoma cell lines

Marples B; Longhurst D; Eastham AM; West CM.

Br J Cancer. 1998; 77(7): 1108-1114.

The radiosensitivity of human fibroblast cell lines correlates with residual levels of DNA double-strand breaks

Zhou PK; Sproston AR; Marples B; West CM; Margison GP; Hendry JH.

Radiother Oncol. 1998; 47(3): 271-276.

Repair of radiation-induced DNA double-strand breaks in human fibroblasts is consistent with a continuous spectrum of repair probability

Foray N; Monroco C; Marples B; Hendry JH; Fertil B; Goodhead DT; Arlett CF; Malaise EP.

Int J Radiat Biol. 1998; 74(5): 551-560.

A comet assay of DNA damage and repair in K562 cells after photodynamic therapy using haematoporphyrin derivative, methylene blue and meso-tetrahydroxyphenylchlorin

McNair FI; Marples B; West CM; Moore JV.

Br J Cancer. 1997; 75(12): 1721-1729.

Low dose hyper-radiosensitivity and increased radioresistance in mammalian cells

Marples B; Lambin P; Skov KA; Joiner MC.

Int J Radiat Biol. 1997; 71(6): 721-735.

A correlation between residual DNA double-strand breaks and clonogenic measurements of radiosensitivity in fibroblasts from preradiotherapy cervix cancer patients

Kiltie AE; Orton CJ; Ryan AJ; Roberts SA; Marples B; Davidson SE; Hunter RD; Margison GP; West CM; Hendry JH.

Int J Radiat Oncol Biol Phys. 1997; 39(5): 1137-1144.

Response of V79 cells to low doses of X-rays and negative pi-mesons: clonogenic survival and DNA strand breaks

Marples B; Adomat H; Koch CJ; Skov KA.

Int J Radiat Biol. 1996; 70(4): 429-436.

Small doses of high-linear energy transfer radiation increase the radioresistance of Chinese hamster V79 cells to subsequent X irradiation

Marples B; Skov KA.

Radiat Res. 1996; 146(4): 382-387.

Hypersensitivity to very-low single radiation doses: its relationship to the adaptive response and induced radioresistance

Joiner MC; Lambin P; Malaise EP; Robson T; Arrand JE; Skov KA; Marples B.

Mutat Res. 1996; 358(2): 171-183.

The elimination of low-dose hypersensitivity in Chinese hamster V79-379A cells by pretreatment with X rays or hydrogen peroxide

Marples B; Joiner MC.

Radiat Res. 1995; 141(2): 160-169.

Can colony size be used to detect low-dose effects?

Spadinger I; Marples B; Matthews J; Skov K.

Radiat Res. 1994; 138(1 Suppl): S21-24.

A preliminary investigation into the extent of increased radioresistance or hyper-radiosensitivity in cells of hamster cell lines known to be deficient in DNA repair

Skov K; Marples B; Matthews JB; Joiner MC; Zhou H.

Radiat Res. 1994; 138(1 Suppl): S126-129.

The effect of oxygen on low-dose hypersensitivity and increased radioresistance in Chinese hamster V79-379A cells

Marples B, Joiner MC, Skov KA.

Radiat Res. 1994; 138(1 Suppl): S17-20.

The effect of two topoisomerase inhibitors on low-dose hypersensitivity and increased radioresistance in Chinese hamster V79 cells

Skov K; Zhou H; Marples B.

Radiat Res. 1994; 138(1 Suppl): S117-120.

The effect of radiosensitizers on the survival response of hypoxic mammalian cells: the low X-ray dose region, hypersensitivity and induced radioresistance

Skov KA; MacPhail HS; Marples B.

Radiat Res. 1994; 138(1 Suppl): S113-116.

The response of Chinese hamster V79-379A cells exposed to negative pi-mesons: evidence that increased radioresistance is dependent on linear energy transfer

Marples B; Lam GK; Zhou H; Skov KA.

Radiat Res. 1994; 138(1 Suppl): S81-84.

Recognition of platinum-induced DNA damage by nuclear proteins: screening for mechanisms

Marples B; Adomat H; Billings PC; Farrell NP; Koch CJ; Skov KA.

Anticancer Drug Des. 1994; 9(5): 389-399.

The response of Chinese hamster V79 cells to low radiation doses: evidence of enhanced sensitivity of the whole cell population

Marples B; Joiner MC.

Radiat Res. 1993; 133(1): 41-51.

The response of tissues to very low doses per fraction: a reflection of induced repair? Recent Results

Joiner MC; Marples B; Johns H.

Cancer Res. 1993; 130: 27-40.

Hypersensitivity of a human tumour cell line to very low radiation doses

Lambin P; Marples B; Fertil B; Malaise EP; Joiner MC.

Int J Radiat Biol. 1993; 63(5): 639-650.

Does induced repair determine the lethal effects of very low radiation doses?

Joiner MC; Marples B.

BJR Suppl. 1992; 24: 74-78.