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Brian Marples, Ph.D.

Publications

Showing all 121 journal articles & 0 books available

Journal Articles

2021
Almahariq MF; Quinn TJ; Arden JD; Roskos PT; Wilson GD; Marples B; Grills IS; Chen PY; Krauss DJ; Chinnaiyan P; Dilworth JT. "Pulsed radiation therapy for the treatment of newly diagnosed glioblastoma". Neuro Oncol. 2021; 23(3): 447-456.

2021
Constine LS; Olch AJ; Jackson A; Hua CH; Ronckers CM; Milano MT; Marcus KJ; Yorke E; Hodgson DC; Howell RM; Hudson MM; Williams JP; Marples B; Kremer LCM; Marks LB; Bentzen SM. "Pediatric Normal Tissue Effects in the Clinic (PENTEC): An International Collaboration to Assess Normal Tissue Radiation Dose-Volume-Response Relationships for Children With Cancer". Int J Radiat Oncol Biol Phys. 2021; in press.

2021
Ahmad A; Shi J; Ansari S; Afaghani J; Molina J; Pollack A; Merscher S; Zeidan YH; Fornoni A; Marples B. "Noninvasive assessment of radiation-induced renal injury in mice". Int J Radiat Biol. 2021; in press.

11/10/2020
Prasanna PG, Woloschak GE, DiCarlo AL, Buchsbaum JC, Schaue D, Chakravarti A, Cucinotta FA, Formenti SC, Guha C, Hu DJ, Khan MK, Kirsch DG, Krishnan S, Leitner WW, Marples B, McBride W, Mehta MP, Rafii S, Sharon E, Sullivan JM, Weichselbaum RR, Ahmed MM, Vikram B, Coleman CN, Held KD. "Low-Dose Radiation Therapy (LDRT) for COVID-19: Benefits or Risks?" Radiation research.. 2020 Nov 10; 194(5):452-464.

8/2020
Udayakumar TS, Betancourt DM, Ahmad A, Tao W, Totiger TM, Patel M, Marples B, Barber G, Pollack A. "Radiation Attenuates Prostate Tumor Antiviral Responses to Vesicular Stomatitis Virus Containing IFN?, Resulting in Pronounced Antitumor Systemic Immune Responses." Molecular cancer research : MCR.. 2020 Aug 0; 18(8):1232-1243. Epub 2020 May 04.

2020
Wilson GD; Wilson TG; Hanna A; Dabjan M; Buelow K; Torma J; Marples B; Galoforo S. "Dacomitinib and gedatolisib in combination with fractionated radiation in head and neck cancer". Clin Transl Radiat Oncol. 2020; 26(15-23).

2020
Marples B; Kerns S. "Oncology Scan: Radiation Biology and Genomic Predictors of Response". Int J Radiat Oncol Biol Phys. 2020; 107(3): 393-397.

2020
Abou Daher A; Francis M; Azzam P; Ahmad A; Eid AA; Fornoni A; Marples B; Zeidan YH. "Modulation of radiation-induced damage of human glomerular endothelial cells by SMPDL3B". FASEB J. 2020; 34(6): 7915-7926.

2020
Pollack A; Chinea FM; Bossart E; Kwon D; Abramowitz MC; Lynne C; Jorda M; Marples B; Patel VN; Wu X; Reis I; Studenski MT; Casillas J; Stoyanova R. "Phase I Trial of MRI-Guided Prostate Cancer Lattice Extreme Ablative Dose (LEAD) Boost Radiation Therapy". Int J Radiat Oncol Biol Phys. 2020; 107(2): 305-315.

2020
Marples B; Wilson GD. "Predicting Outcome using Genomic-Based Liquid Biomarkers". Int J Radiat Oncol Biol Phys. 2020; 106(1): 1-4.

2020
Marples B. "The Need for Accurate Reporting of Dosimetric Conditions in Radiobiology Studies". Int J Radiat Oncol Biol Phys. 2020; 106(2): 253-254.

2019
Shah SS; Rodriguez GA; Musick A; Walters WM; de Cordoba N; Barbarite E; Marlow MM; Marples B; Prince JS; Komotar RJ; Vanni S; Graham RM. "Targeting Glioblastoma Stem Cells with 2-Deoxy-D-Glucose (2-DG) Potentiates Radiation-Induced Unfolded Protein Response (UPR)". Cancers (Basel). 2019; 11(2): 159.

2018
Surnar B; Basu U; Banik B; Ahmad A; Marples B; Kolishetti N; Dhar S. "Nanotechnology-mediated crossing of two impermeable membranes to modulate the stars of the neurovascular unit for neuroprotection". Proc Natl Acad Sci U S A. 2018; 115(52): E12333-E12342.

2018
Surnar B; Kolishetti N; Basu U; Ahmad A; Goka E; Marples B; Kolb D; Lippman ME; Dhar S. "Reduction of Cisplatin-Induced Ototoxicity without Compromising Its Antitumor Activity". Biochemistry. 2018; 57(46): 6500-6513.

2018
Pathak RK; Basu U; Ahmad A; Sarkar S; Kumar A; Surnar B; Ansari S; Wilczek K; Ivan ME; Marples B; Kolishetti N; Dhar S. "A designer bow-tie combination therapeutic platform: An approach to resistant cancer treatment by simultaneous delivery of cytotoxic and anti-inflammatory agents and radiation". Biomaterials. 2018; 187: 117-129.

2018
Blas K; Wilson TG; Tonlaar N; Galoforo S; Hana A; Marples B; Wilson GD. "Dual blockade of PI3K and MEK in combination with radiation in head and neck cancer". Clin Transl Radiat Oncol. 2018; 11: 1-10.

2018
Kirsch DG; Diehn M; Kesarwala AH; Maity A; Morgan MA; Schwarz JK; Bristow R; Demaria S; Eke I; Griffin RJ; Haas-Kogan D; Higgins GS; Kimmelman AC; Kimple RJ; Lombaert IM; Ma L; Marples B; Pajonk F; Park CC; Schaue D; Tran PT; Willers H; Wouters BG; Bernhard EJ. "The Future of Radiobiology". J Natl Cancer Inst. 2018; 110(4): 329-340.

2018
Marples B; Welford SM. "Radiation Biology and Circulating Tumor Cells". Int J Radiat Oncol Biol Phys. 2018; 100(4): 813-815.

2017
Abou Daher A; El Jalkh T; Eid AA; Fornoni A; Marples B; Zeidan YH. "Translational Aspects of Sphingolipid Metabolism in Renal Disorders". Int J Mol Sci. 2017; 18(12): 2528.

2017
Parra NA; Pollack A; Chinea FM; Abramowitz MC; Marples B; Munera F; Castillo R; Kryvenko ON; Punnen S; Stoyanova R. "Automatic Detection and Quantitative DCE-MRI Scoring of Prostate Cancer Aggressiveness". Front Oncol. 2017; 7: 259.

2017
Tonlaar N; Galoforo S; Thibodeau BJ; Ahmed S; Wilson TG; Yumpo Cardenas P; Marples B; Wilson GD. "Antitumor activity of the dual PI3K/MTOR inhibitor, PF-04691502, in combination with radiation in head and neck cancer". Radiother Oncol. 2017; 124(3): 504-512.

2017
Marples B; Pollack A. "Molecular Profiling in the Practice of Radiation Oncology". Oncology (Williston Park). 2017; 31(7): 571-572.

2017
Marples B; Dhar S. "Radiobiology and the Renewed Potential for Nanoparticles". Int J Radiat Oncol Biol Phys. 2017; 98(3): 489-491.

2017
Ahmad A; Mitrofanova A; Bielawski J; Yang Y; Marples B; Fornoni A; Zeidan YH. "Sphingomyelinase-like phosphodiesterase 3b mediates radiation-induced damage of renal podocytes". FASEB J. 2017; 31(2): 771-780.

2016
Zwaans BM; Krueger S; Bartolone SN; Chancellor MB; Marples B; Lamb LE. "Modeling of chronic radiation-induced cystitis in mice". Adv Radiat Oncol. 2016; 1(4): 333-343.

2016
Dabjan MB; Buck CM; Jackson IL; Vujaskovic Z; Marples B; Down JD. "A survey of changing trends in modelling radiation lung injury in mice: bringing out the good, the bad, and the uncertain". Lab Invest. 2016; 96(9): 936-949.

2016
Kane JL; Krueger SA; Hanna A; Raffel TR; Wilson GD; Madlambayan GJ; Marples B. "Effect of Irradiation on Tumor Microenvironment and Bone Marrow Cell Migration in a Preclinical Tumor Model". Int J Radiat Oncol Biol Phys. 2016; 96(1): 170-178.

2016
Meyer K; Krueger SA; Kane JL; Wilson TG; Hanna A; Dabjan M; Hege KM; Wilson GD; Grills I; Marples B. "Pulsed Radiation Therapy With Concurrent Cisplatin Results in Superior Tumor Growth Delay in a Head and Neck Squamous Cell Carcinoma Murine Model". Int J Radiat Oncol Biol Phys. 2016; 96(1): 161-169.

2016
Wilson GD; Marples B. "A New Use for an Old Treatment: Radiation Therapy and Alzheimer's Disease". Radiat Res. 2016; 185(5): 443-448.

2016
Marples B; McGee M; Callan S; Bowen SE; Thibodeau BJ; Michael DB; Wilson GD; Maddens ME; Fontanesi J; Martinez AA. "Cranial irradiation significantly reduces beta amyloid plaques in the brain and improves cognition in a murine model of Alzheimer's Disease (AD)". Radiother Oncol. 2016; 118(3): 579-580.

2016
Wilson GD; Thibodeau BJ; Fortier LE; Pruetz BL; Galoforo S; Marples B; Baschnagel AM; Akervall J; Huang J. "Cancer Stem Cell Signaling during Repopulation in Head and Neck Cancer". Stem Cells Int. 2016; 2016(1894782).

2016
Marples B; McGee M; Callan S; Bowen SE; Thibodeau BJ; Michael DB; Wilson GD; Maddens ME; Fontanesi J; Martinez AA. "Cranial irradiation significantly reduces beta amyloid plaques in the brain and improves cognition in a murine model of Alzheimer's Disease (AD)". Radiother Oncol. 2016; 118(1): 43-51.

2016
McDermott N; Meunier A; Mooney B; Nortey G; Hernandez C; Hurley S; Lynam-Lennon N; Barsoom SH; Bowman KJ; Marples B; Jones GD; Marignol L. "Fractionated radiation exposure amplifies the radioresistant nature of prostate cancer cells". Sci Rep. 2016; 6: 34796.

2015
Purcell DJ; Chauhan S; Jimenez-Stinson D; Elliott KR; Tsewang TD; Lee YH; Marples B; Lee DY. "Novel CARM1-Interacting Protein, DZIP3, Is a Transcriptional Coactivator of Estrogen Receptor-?". Mol Endocrinol. 2015; 29(12): 1708-1719.

2015
Wobb J; Krueger SA; Kane JL; Galoforo S; Grills IS; Wilson GD; Marples B. "The Effects of Pulsed Radiation Therapy on Tumor Oxygenation in 2 Murine Models of Head and Neck Squamous Cell Carcinoma". Int J Radiat Oncol Biol Phys. 2015; 92(4): 820-828.

2015
Rajaganapathy BR; Janicki JJ; Levanovich P; Tyagi P; Hafron J; Chancellor MB; Krueger S; Marples B. "Intravesical Liposomal Tacrolimus Protects against Radiation Cystitis Induced by 3-Beam Targeted Bladder Radiation". J Urol. 2015; 194(2): 578-584.

2015
Enns L; Rasouli-Nia A; Hendzel M; Marples B; Weinfeld M. "Association of ATM activation and DNA repair with induced radioresistance after low-dose irradiation". Radiat Prot Dosimetry. 2015; 166(1-4): 131-136.

2014
Wilson GD; Thibodeau BJ; Fortier LE; Pruetz BL; Galoforo S; Baschnagel AM; Chunta J; Oliver Wong CY; Yan D; Marples B; Huang J. "Glucose metabolism gene expression patterns and tumor uptake of ¹?F-fluorodeoxyglucose after radiation treatment". Int J Radiat Oncol Biol Phys. 2014; 90(3): 620-627.

2014
Wilson GD; Thibodeau BJ; Fortier LE; Pruetz BL; Galoforo S; Akervall J; Marples B; Huang J. "Gene expression changes during repopulation in a head and neck cancer xenograft". Radiother Oncol. 2014; 113(1): 139-145.

2014
Martin LM; Marples B; Lynch TH; Hollywood D; Marignol L. "Exposure to low dose ionising radiation: Molecular and clinical consequences". Cancer Lett. 2014; 349(1): 98-106.

2014
Dilworth JT; Krueger SA; Wilson GD; Marples B. "Preclinical models for translational research should maintain pace with modern clinical practice". Int J Radiat Oncol Biol Phys. 2014; 88(3): 540-544.

2014
Huang J; Chunta JL; Amin M; Lee DY; Grills IS; Oliver Wong CY; Marples B; Yan D; Wilson GD. "Early treatment response monitoring using 2-deoxy-2-[ 18F]fluoro-D-glucose positron emission tomography imaging during fractionated radiotherapy of head neck cancer xenografts". Biomed Res Int. 2014; 2014: 598052.

2014
Wallner PE; Anscher MS; Barker CA; Bassetti M; Bristow RG; Cha YI; Dicker AP; Formenti SC; Graves EE; Hahn SM; Hei TK; Kimmelman AC; Kirsch DG; Kozak KR; Lawrence TS; Marples B; McBride WH; Mikkelsen RB; Park CC; Weidhaas JB; Zietman AL; Steinberg M. "Current status and recommendations for the future of research, teaching, and testing in the biological sciences of radiation oncology: report of the American Society for Radiation Oncology Cancer Biology/Radiation Biology Task Force, executive summary". Int J Radiat Oncol Biol Phys. 2014; 88(1): 11-17.

2013
Kane J; Krueger SA; Dilworth JT; Torma JT; Wilson GD; Marples B; Madlambayan GJ. "Hematopoietic stem and progenitor cell migration after hypofractionated radiation therapy in a murine model". Int J Radiat Oncol Biol Phys. 2013; 87(5): 1162-1170.

2013
Schoenherr D; Krueger SA; Martin L; Marignol L; Wilson GD; Marples B. "Determining if low dose hyper-radiosensitivity (HRS) can be exploited to provide a therapeutic advantage: a cell line study in four glioblastoma multiforme (GBM) cell lines". Int J Radiat Biol. 2013; 89(12): 1009-1016.

2013
Lee DY, Chunta JL, Park SS, Huang J, Martinez AA, Grills IS, Krueger SA, Wilson GD, Marples B. "Pulsed versus conventional radiation therapy in combination with temozolomide in a murine orthotopic model of glioblastoma multiforme". Int J Radiat Oncol Biol Phys. 2013; 86(5): 978-985.

2013
Dilworth JT; Krueger SA; Dabjan M; Grills IS; Torma J; Wilson GD; Marples B. "Pulsed low-dose irradiation of orthotopic glioblastoma multiforme (GBM) in a pre-clinical model: effects on vascularization and tumor control". Radiother Oncol. 2013; 108(1): 149-154.

2013
Martin LM; Marples B; Lynch TH; Hollywood D; Marignol L. "Exposure to low dose ionising radiation: molecular and clinical consequences". Cancer Lett. 2013; 338(2): 209-218.

2013
Martin LM; Marples B; Davies AM; Atzberger A; Edwards C; Lynch TH; Hollywood D; Marignol L. "DNA mismatch repair protein MSH2 dictates cellular survival in response to low dose radiation in endometrial carcinoma cells". Cancer Lett. 2013; 335(1): 19-25.

2013
Tyagi N; Yang K; Sandhu R; Yan D; Park SS; Chen PY; Marples B. "External beam pulsed low dose radiotherapy using volumetric modulated arc therapy: planning and delivery". Med Phys. 2013; 40(1): 011704.

2013
Wilson GD; Marples B; Galoforo S; Geddes TJ; Thibodeau BJ; Grénman R; Akervall J. "Isolation and genomic characterization of stem cells in head and neck cancer". Head Neck. 2013; 35(11): 1573-1582.

2012
Huang J; Chunta JL; Amin M; Lee DY; Grills IS; Wong CY; Yan D, Marples B, Martinez AA, Wilson GD. "Detailed characterization of the early response of head-neck cancer xenografts to irradiation using (18)F-FDG-PET imaging". Int J Radiat Oncol Biol Phys. 2012; 84(2): 485-491.

2011
Park SS; Chunta JL; Robertson JM; Martinez AA; Oliver Wong CY; Amin M; Wilson GD; Marples B. "MicroPET/CT imaging of an orthotopic model of human glioblastoma multiforme and evaluation of pulsed low-dose irradiation". Int J Radiat Oncol Biol Phys. 2011; 80(3): 885-892.

2011
Swanson TA; Krueger SA; Galoforo S; Thibodeau BJ; Martinez AA; Wilson GD; Marples B. "TMPRSS2/ERG fusion gene expression alters chemo- and radio-responsiveness in cell culture models of androgen independent prostate cancer". Prostate. 2011; 71(14): 1548-1558.

2011
Marples B; Downing L; Sawarynski KE; Finkelstein JN; Williams JP; Martinez AA; Wilson GD; Sims MD. "Pulmonary injury after combined exposures to low-dose low-LET radiation and fungal spores". Radiat Res. 2011; 175(4): 501-509.

2010
Suen AW, Galoforo S, Marples B, McGonagle M, Downing L, Martinez AA, Robertson JM, Wilson GD. "Sorafenib and radiation: a promising combination in colorectal cancer". Int J Radiat Oncol Biol Phys. 2010; 78(1): 213-220.

2010
Krueger SA; Wilson GD; Piasentin E; Joiner MC; Marples B. "The effects of G2-phase enrichment and checkpoint abrogation on low-dose hyper-radiosensitivity". Int J Radiat Oncol Biol Phys. 2010; 77(5): 1509-1517.

2010
Joiner MC; Mogili N; Marples B; Burmeister J. "Significant dose can be lost by extended delivery times in IMRT with x rays but not high-LET radiations". Med Phys. 2010; 37(6): 2457-2465.

2010
Kulkarni R; Marples B; Balasubramaniam M; Thomas RA; Tucker JD. "Mitochondrial gene expression changes in normal and mitochondrial mutant cells after exposure to ionizing radiation". Radiat Res. 2010; 173(5): 635-644.

2010
Martin LM; Marples B; Coffey M; Lawler M; Lynch TH; Hollywood D; Marignol L. "DNA mismatch repair and the DNA damage response to ionizing radiation: making sense of apparently conflicting data". Cancer Treat Rev. 2010; 36(7): 518-527.

2010
Hasan Y; Schoenherr D; Martinez AA; Wilson GD; Marples B. "Prostate-specific natural health products (dietary supplements) radiosensitize normal prostate cells". Int J Radiat Oncol Biol Phys. 2010; 76(3): 896-904.

2010
Asur R; Balasubramaniam M; Marples B; Thomas RA; Tucker JD. "Bystander effects induced by chemicals and ionizing radiation: evaluation of changes in gene expression of downstream MAPK targets". Mutagenesis. 2010; 25(3): 271-279.

2010
Asur R; Balasubramaniam M; Marples B; Thomas RA; Tucker JD. "Involvement of MAPK proteins in bystander effects induced by chemicals and ionizing radiation". Mutat Res. 2010; 686(1-2): 15-29.

2010
Downing L; Sawarynski KE; Li J; McGonagle M; Sims MD; Marples B. "A simple quantitative method for assessing pulmonary damage after x irradiation". Radiat Res. 2010; 173(4): 536-544.

2009
Martin L; Marples B; Coffey M; Lawler M; Hollywood D; Marignol L. "Recognition of O6MeG lesions by MGMT and mismatch repair proficiency may be a prerequisite for low-dose radiation hypersensitivity". Radiat Res. 2009; 172(4): 405-413.

2009
Campbell JM; Wong CO; Muzik O; Marples B; Joiner M; Burmeister J. "Early dose response to yttrium-90 microsphere treatment of metastatic liver cancer by a patient-specific method using single photon emission computed tomography and positron emission tomography". Int J Radiat Oncol Biol Phys. 2009; 74(1): 313-320.

2008
Marples B; Collis SJ. "Low-dose hyper-radiosensitivity: past, present, and future". Int J Radiat Oncol Biol Phys. 2008; 70(5): 1310-1318.

2007
Krueger SA; Collis SJ; Joiner MC; Wilson GD; Marples B. "Transition in survival from low-dose hyper-radiosensitivity to increased radioresistance is independent of activation of ATM Ser1981 activity". Int J Radiat Oncol Biol Phys. 2007; 69(4): 1262-1271.

2007
Wilson GD; Marples B. "Flow cytometry in radiation research: past, present and future". Radiat Res. 2007; 168(4): 391-403.

2007
Krueger SA; Joiner MC; Weinfeld M; Piasentin E; Marples B. "Role of apoptosis in low-dose hyper-radiosensitivity". Radiat Res. 2007; 167(3): 260-267.

2006
Colen CB; Seraji-Bozorgzad N; Marples B; Galloway MP; Sloan AE; Mathupala SP. "Metabolic remodeling of malignant gliomas for enhanced sensitization during radiotherapy: an in vitro study". Neurosurgery. 2006; 59(6): 1313-1323.

2006
Wykes SM; Piasentin E; Joiner MC; Wilson GD; Marples B. "Low-dose hyper-radiosensitivity is not caused by a failure to recognize DNA double-strand breaks". Radiat Res. 2006; 165(5): 516-524.

2005
Greco O; Powell TM; Marples B; Joiner MC; Scott SD. "Gene therapy vectors containing CArG elements from the Egr1 gene are activated by neutron irradiation, cisplatin and doxorubicin". Cancer Gene Ther. 2005; 12(7): 655-662.

2005
Greco O; Marples B; Wilson GD; Joiner MC; Scott SD. "Radiation-induced gene therapy". Radiat Res. 2005; 163(6): 707-708.

2004
Hillman GG; Wang Y; Kucuk O; Che M; Doerge DR; Yudelev M; Joiner MC; Marples B; Forman JD; Sarkar FH. "Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model". Mol Cancer Ther. 2004; 3(10): 1271-1279.

2004
Tucker JD; Marples B; Ramsey MJ; Lutze-Mann LH. "Persistence of chromosome aberrations in mice acutely exposed to 56Fe+26 ions". Radiat Res. 2004; 161(6): 648-655.

2004
Page PC; Barros D; Buckley BR; Ardakani A; Marples BA. "Organocatalysis of asymmetric epoxidation mediated by iminium salts under nonaqueous conditions". J Org Chem. 2004; 69(10): 3595-3597.

2004
Chalmers A; Johnston P; Woodcock M; Joiner M; Marples B. "PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation". Int J Radiat Oncol Biol Phys. 2004; 58(2): 410-419.

2004
Scott SD; Marples B. "Radiation-activated antitumor vectors". Methods Mol Med. 2004; 90: 389-402.

2004
Marples B; Wouters BG; Collis SJ; Chalmers AJ; Joiner MC. "Low-dose hyper-radiosensitivity: a consequence of ineffective cell cycle arrest of radiation-damaged G2-phase cells". Radiat Res. 2004; 161(3): 247-255.

2004
Marples B. "Is low-dose hyper-radiosensitivity a measure of G2-phase cell radiosensitivity?". Cancer Metastasis Rev. 2004; 23(3-4): 197-207.

2003
Greco O; Marples B; Joiner MC; Scott SD. "How to overcome (and exploit) tumor hypoxia for targeted gene therapy". J Cell Physiol. 2003; 197(3): 312-325.

2003
Marples B; Greco O; Joiner MC; Scott SD. "Radiogenetic therapy: strategies to overcome tumor resistance". Curr Pharm Des. 2003; 9(26): 2105-2112.

2003
Short SC; Woodcock M; Marples B; Joiner MC. "Effects of cell cycle phase on low-dose hyper-radiosensitivity". Int J Radiat Biol. 2003; 79(2): 99-105.

2003
Marples B; Wouters BG; Joiner MC. "An association between the radiation-induced arrest of G2-phase cells and low-dose hyper-radiosensitivity: a plausible underlying mechanism?". Radiat Res. 2003; 160(1): 38-45.

2002
Greco O; Scott SD; Marples B; Dachs GU. "Cancer gene therapy: 'delivery, delivery, delivery'". Front Biosci. 2002; 7: d1516-24.

2002
Marples B; Greco O; Joiner MC; Scott SD. "Molecular approaches to chemo-radiotherapy". Eur J Cancer. 2002; 38(2): 231-239.

2002
Schaue D; Marples B; Trott KR. "The effects of low-dose X-irradiation on the oxidative burst in stimulated macrophages". Int J Radiat Biol. 2002; 78(7): 567-576.

2002
Scott SD; Joiner MC; Marples B. "Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy". Gene Ther. 2002; 9(20): 1396-1402.

2002
Greco O; Marples B; Dachs GU; Williams KJ; Patterson AV; Scott SD. "Novel chimeric gene promoters responsive to hypoxia and ionizing radiation". Gene Ther. 2002; 9(20): 1403-1411.

2002
Marples B; Cann NE; Mitchell CR; Johnston PJ; Joiner MC. "Evidence for the involvement of DNA-dependent protein kinase in the phenomena of low dose hyper-radiosensitivity and increased radioresistance". Int J Radiat Biol. 2002; 78(12): 1139-1147.

2001
Joiner MC; Marples B; Lambin P; Short SC; Turesson I. "Low-dose hypersensitivity: current status and possible mechanisms". Int J Radiat Oncol Biol Phys. 2001; 49(2): 379-389.

2000
Ward TH; Marples B. "Technical report: SYBR Green I and the improved sensitivity of the single-cell electrophoresis assay". Int J Radiat Biol. 2000; 76(1): 61-65.

2000
Marples B; Joiner MC. "Modification of survival by DNA repair modifiers: a probable explanation for the phenomenon of increased radioresistance". Int J Radiat Biol. 2000; 76(3): 305-312.

2000
Marples B; Scott SD; Hendry JH; Embleton MJ; Lashford LS; Margison GP. "Development of synthetic promoters for radiation-mediated gene therapy". Gene Ther. 2000; 7(6): 511-517.

2000
Scott SD; Marples B; Hendry JH; Lashford LS; Embleton MJ; Hunter RD; Howell A; Margison GP. "A radiation-controlled molecular switch for use in gene therapy of cancer". Gene Ther. 2000; 7(13): 1121-1125.

2000
Scott SD; Marples B. "Comment on the use of the cre/loxP recombinase system for gene therapy vectors". Gene Ther. 2000; 7(19): 1706.

1999
Joiner MC; Lambin P; Marples B. "Adaptive response and induced resistance". C R Acad Sci III. 1999; 322(2-3): 167-175.

1999
Eastham AM; Marples B; Kiltie AE; Orton CJ; West CM. "Fibroblast radiosensitivity measured using the comet DNA-damage assay correlates with clonogenic survival parameters". Br J Cancer. 1999; 79(9-10): 1366-1371.

1998
Haines G; Marples B; Daniel P; Morris I. "DNA damage in human and mouse spermatozoa after in vitro-irradiation assessed by the comet assay". Adv Exp Med Biol. 1998; 444(79-91).

1998
Marples B; Longhurst D; Eastham AM; West CM. "The ratio of initial/residual DNA damage predicts intrinsic radiosensitivity in seven cervix carcinoma cell lines". Br J Cancer. 1998; 77(7): 1108-1114.

1998
Zhou PK; Sproston AR; Marples B; West CM; Margison GP; Hendry JH. "The radiosensitivity of human fibroblast cell lines correlates with residual levels of DNA double-strand breaks". Radiother Oncol. 1998; 47(3): 271-276.

1998
Foray N; Monroco C; Marples B; Hendry JH; Fertil B; Goodhead DT; Arlett CF; Malaise EP. "Repair of radiation-induced DNA double-strand breaks in human fibroblasts is consistent with a continuous spectrum of repair probability". Int J Radiat Biol. 1998; 74(5): 551-560.

1997
McNair FI; Marples B; West CM; Moore JV. "A comet assay of DNA damage and repair in K562 cells after photodynamic therapy using haematoporphyrin derivative, methylene blue and meso-tetrahydroxyphenylchlorin". Br J Cancer. 1997; 75(12): 1721-1729.

1997
Marples B; Lambin P; Skov KA; Joiner MC. "Low dose hyper-radiosensitivity and increased radioresistance in mammalian cells". Int J Radiat Biol. 1997; 71(6): 721-735.

1997
Kiltie AE; Orton CJ; Ryan AJ; Roberts SA; Marples B; Davidson SE; Hunter RD; Margison GP; West CM; Hendry JH. "A correlation between residual DNA double-strand breaks and clonogenic measurements of radiosensitivity in fibroblasts from preradiotherapy cervix cancer patients". Int J Radiat Oncol Biol Phys. 1997; 39(5): 1137-1144.

1996
Marples B; Adomat H; Koch CJ; Skov KA. "Response of V79 cells to low doses of X-rays and negative pi-mesons: clonogenic survival and DNA strand breaks". Int J Radiat Biol. 1996; 70(4): 429-436.

1996
Marples B; Skov KA. "Small doses of high-linear energy transfer radiation increase the radioresistance of Chinese hamster V79 cells to subsequent X irradiation". Radiat Res. 1996; 146(4): 382-387.

1996
Joiner MC; Lambin P; Malaise EP; Robson T; Arrand JE; Skov KA; Marples B. "Hypersensitivity to very-low single radiation doses: its relationship to the adaptive response and induced radioresistance". Mutat Res. 1996; 358(2): 171-183.

1995
Marples B; Joiner MC. "The elimination of low-dose hypersensitivity in Chinese hamster V79-379A cells by pretreatment with X rays or hydrogen peroxide". Radiat Res. 1995; 141(2): 160-169.

1994
Spadinger I; Marples B; Matthews J; Skov K. "Can colony size be used to detect low-dose effects?". Radiat Res. 1994; 138(1 Suppl): S21-24.

1994
Skov K; Marples B; Matthews JB; Joiner MC; Zhou H. "A preliminary investigation into the extent of increased radioresistance or hyper-radiosensitivity in cells of hamster cell lines known to be deficient in DNA repair". Radiat Res. 1994; 138(1 Suppl): S126-129.

1994
Marples B, Joiner MC, Skov KA. "The effect of oxygen on low-dose hypersensitivity and increased radioresistance in Chinese hamster V79-379A cells". Radiat Res. 1994; 138(1 Suppl): S17-20.

1994
Skov K; Zhou H; Marples B. "The effect of two topoisomerase inhibitors on low-dose hypersensitivity and increased radioresistance in Chinese hamster V79 cells". Radiat Res. 1994; 138(1 Suppl): S117-120.

1994
Skov KA; MacPhail HS; Marples B. "The effect of radiosensitizers on the survival response of hypoxic mammalian cells: the low X-ray dose region, hypersensitivity and induced radioresistance". Radiat Res. 1994; 138(1 Suppl): S113-116.

1994
Marples B; Lam GK; Zhou H; Skov KA. "The response of Chinese hamster V79-379A cells exposed to negative pi-mesons: evidence that increased radioresistance is dependent on linear energy transfer". Radiat Res. 1994; 138(1 Suppl): S81-84.

1994
Marples B; Adomat H; Billings PC; Farrell NP; Koch CJ; Skov KA. "Recognition of platinum-induced DNA damage by nuclear proteins: screening for mechanisms". Anticancer Drug Des. 1994; 9(5): 389-399.

1993
Marples B; Joiner MC. "The response of Chinese hamster V79 cells to low radiation doses: evidence of enhanced sensitivity of the whole cell population". Radiat Res. 1993; 133(1): 41-51.

1993
Joiner MC; Marples B; Johns H. "The response of tissues to very low doses per fraction: a reflection of induced repair? Recent Results". Cancer Res. 1993; 130: 27-40.

1993
Lambin P; Marples B; Fertil B; Malaise EP; Joiner MC. "Hypersensitivity of a human tumour cell line to very low radiation doses". Int J Radiat Biol. 1993; 63(5): 639-650.

1992
Joiner MC; Marples B. "Does induced repair determine the lethal effects of very low radiation doses?". BJR Suppl. 1992; 24: 74-78.