Department of Pediatrics - Critical Care Research

Investigators

We are proud of the accomplishments of our faculty who inspire and lead our research efforts, and continuously push the boundaries of current knowledge helping to make tomorrow’s state-of-the-art even better.  Here are just a few of their achievements.
  • As part of the BloodNet and PALISI networks Drs. Cholette and Daugherty are site Co-PIs for the ABC-trial, an international study examining the impact of the age of blood cells in pediatric critically ill patients.
  • Through the PALISI network Drs. Ackerman, Daugherty and Cholette, are participating in PANGEA (the Prevalence of Acute critical Neurological disease in children; a Global Epidemiological Assessment study) led by Dr. Adrienne Randolph at Boston Children’s Hospital.
  • Dr. van der Jagt is the university’s Site PI for an NHLBI (NIH) study, “THAPCA Trials (Therapeutic Hypothermia After Cardiac Arrest),” a 6 year multi-center study project involving 34 institutions.  Dr. van der Jagt has also been an active as a National Faculty Member of the American Heart Association's Advanced Pediatric Life Support Course (PALS). 
  • Dr Ackerman has recently taken a leadership position in The Society for Pediatric Research (SPR).

Investigators' Research Interests

Kate Ackerman, M.D.

  • diaphragmLaboratory investigation of the developmental mechanisms and genetics of structural birth defects that cause critical illness in neonates
  • Laboratory focus on developmental diaphragmatic defects, pulmonary hypoplasia, and early lung patterning
  • Investigating models of congenital heart disease and fetal obstructive uropathy

Jill Cholette, M.D.

  • Blood cell utilization, modification and impact on inflammation and immune modulation
  • Clinical outcomes after blood transfusions in children with congenital heart disease status post cardiac surgery
  • Venous thrombosis prevention, as well as management, particularly in pediatric cardiac surgery and in association with central venous lines

Barbara R. Ferdman, M.D.

  • Clinical studies and images to determine brain development and neurodevelopmental outcomes in children with congenital heart disease and other critical illness

Karen Powers, M.D.

  • Non-invasive measures of cardiac output and volume measurements in critically ill infants and children

Elise van der Jagt, M.D.

  • Multi-center control trials studying the morbidity and mortality of cooling pediatric patients status post cardiac arrest
  • Effectiveness of medical simulation as both a teaching tool and assessment tool in the Pediatric Intensive Care Unit